Search Our Scientific Publications & Authors

J Matern Fetal Neonatal Med 2021 May 12:1-3. Epub 2021 May 12.

Department of Paediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland.

Introduction: Centralization of very preterm deliveries to level 3 hospitals is recommended to improve infant survival and prevent brain injury. We studied the clinical practices of centralization from level 2 to level 3 hospitals in cases of threatening very preterm delivery in Finland.

Materials And Methods: Obstetricians in all 16 level 2 hospitals in Finland were invited to participate in an online survey regarding antenatal transfer to level 3 hospitals among women with threatened delivery below 32 gestational weeks. Read More

J Matern Fetal Neonatal Med 2021 May 12:1-10. Epub 2021 May 12.

Department of Obstetrics and Gynecology, Maternité Aliénor d'Aquitaine, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.

Objective: To define for women at low obstetric risk methods of management that respect the rhythm and the spontaneous course of giving birth as well as each woman's preferences.

Methods: These clinical practice guidelines were developed through professional consensus based on an analysis of the literature and of the French and international guidelines available on this topic.

Results: Labor should be monitored with a partograph (professional consensus). Read More

Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399

Department of Obstetrics and Gynecology, USC/Keck School of Medicine, 2020 Zonal Avenue, IRD 236, Los Angeles, CA 90033, USA. Electronic address:

Macrosomia results from abnormal fetal growth and can lead to serious consequences for the mother and fetus. In cases of suspected macrosomia, patients must be counseled carefully regarding a delivery plan, and Cesarean section should be considered when indicated. Techniques to assess for suspected macrosomia include clinical measurements, ultrasound, and MRI. Read More

Obstet Gynecol Clin North Am 2021 Jun;48(2):325-337

Department of Obstetrics and Gynecology, Indiana University School of Medicine, 550 N. University Boulevard, UH 2440, Indianapolis, IN 46202, USA. Electronic address:

Large for gestational age birth weight is associated with adverse short- and long-term outcomes. Infants born with large for gestational age birth weight are at increased risk for neonatal intensive care unit admission, respiratory distress, neonatal metabolic abnormalities including hypoglycemia, birth trauma, and even stillbirth or neonatal death. The risk for many of these complications increases with higher birth weights. Read More

Am J Obstet Gynecol MFM 2021 May 5:100387. Epub 2021 May 5.

Department of Medicine and Surgery, Obstetrics and Gynecology Unit, University of Parma, Parma, Italy.

Zoonoses Public Health 2021 May 5. Epub 2021 May 5.

Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.

Staphylococcus aureus infection led to a case of goat abortion, and four veterinarians contracted S. aureus infection from the goat during and after the abortion. Three veterinarians assisted a doe during the dystocic delivery of a dead foetus. Read More

J Hand Ther 2021 Mar 6. Epub 2021 Mar 6.

Clinical Fellow, Trauma & Orthopaedics, Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom.

Animals (Basel) 2021 Apr 30;11(5). Epub 2021 Apr 30.

Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.

Prediction of hyperketonemia (HYK), a postpartum metabolic disorder in dairy cows, through use of cow and milk data has allowed for high-throughput detection and monitoring during monthly milk sampling. The objective of this study was to determine associations between predicted HYK (pHYK) and production parameters in a dataset generated from routine milk analysis samples. Data from 240,714 lactations across 335 farms were analyzed with multiple linear regression models to determine HYK status. Read More

Am J Perinatol 2021 May 3. Epub 2021 May 3.

Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon.

Objective:  The aim of the study is to evaluate differences in maternal and neonatal outcomes based on updated criteria for defining active labor at 6 cm of cervical dilation and to determine if these recommendations are cost-effective.

Study Design:  A decision-analytic model was built using TreeAge Pro 2020 software. We included maternal outcomes of mode of delivery, endometritis, postpartum hemorrhage requiring transfusion, and death. Read More

Prenat Diagn 2021 May 3. Epub 2021 May 3.

Department of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University, Meaung, Chiang Mai, Thailand.

Early detection of Beckwith-Wiedemann syndrome (BWS) is very important since it is very useful regarding counseling of parents concerning the risk of developing embryonic tumors, selection of the mode of delivery due to potential adrenal cysts that might bleed during labor, prevention of neonatal hypoglycemia and even options of pregnancy termination in non-viable fetuses. This report describes the prenatal classic sonographic triad of fetal BWS (omphalocele, macrosomia, macroglossia) and other supporting findings (hepatomegaly, adrenal enlargement) as well as additional postnatal evidence. Also, it demonstrates new molecular genetic evidence potentially associated with the disease (the presence of a novel heterozygous c. Read More

J Obstet Gynaecol 2021 May 2:1-6. Epub 2021 May 2.

Department of Obstetrics and Gynaecology, The Royal Brisbane and Women's Hospital, Brisbane, Australia.

The aim of this study was to determine the main contributors to caesarean section (CS) rates at an Australian tertiary hospital. We conducted a retrospective review of women who delivered in an Australian tertiary hospital between 2014 and 2017. Women were allocated according to a modified Robson Ten-Group Classification System and CS indications were collected in nulliparous women and women with previous CS. Read More

J Obstet Gynaecol 2021 May 2:1-5. Epub 2021 May 2.

Department of Obstetrics and Gynaecology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

We compared the labour pattern in the active phase of labour, defined at 4 cm versus 6 cm cervical dilatation, in a South Asian population. This was a prospective observational study where 500 low risk nulliparous women were recruited. Our aim was to study, the average labour pattern curve of all parturients. Read More

Drug Des Devel Ther 2021 23;15:1717-1724. Epub 2021 Apr 23.

Department of Orthopedics, Minhang Hospital, Fudan University, Shanghai, 201199, People's Republic of China.

Background: Osteonecrosis of the femoral head (ONFH) seriously affects the quality of life and labor ability of patients. It is urgent and vital to find the methods for necrosis clinical treatment.

Objective: This study aims to study the potential protective effects of Alendronate in the early stage of femur head necrosis. Read More

Am J Reprod Immunol 2021 May 2:e13436. Epub 2021 May 2.

NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China.

Problem: Circadian rhythms are involved not only in the repair and regeneration of the immune system, but may also be associated with regulation of inflammation and immune responses. Rev-erbα could constitute a link between immunity and circadian rhythms since it is a transcription factor that regulates circadian rhythms and has functions in multiple physiological and pathological processes. Decidual macrophages (dMφs) play crucial roles in immune balance at the maternal-fetal interface, and abnormal macrophage polarization is related to adverse pregnancy outcomes, such as infertility, recurrent spontaneous abortion and preterm labor. Read More

Vet Med Sci 2021 May 1. Epub 2021 May 1.

Department of Gynecology, Obstetrics & Reproductive Health, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh.

Background: The incidence of dystocia in cats is relatively low compared to that in other pet and farm animals. However, when dystocia occurs in cats, manual, medicinal or surgical intervention is required.

Objectives: Here, we report a caesarean section (C-section) in a Bangladeshi domestic cat that suffered from dystocia due to partial primary uterine inertia. Read More

J Matern Fetal Neonatal Med 2020 Dec 1:1-8. Epub 2020 Dec 1.

Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Ramat-Gan, Israel.

Objective: Among deliveries <34 weeks, there is inconclusive evidence regarding the preferred route of delivery when there is a need to expedite delivery during the second stage of labor. As it is unreasonable that future randomized controlled trials will be conducted to settle this query, every clinical data concerning this topic, may be helpful. We aim to compare neonatal outcomes among women undergoing emergent cesarean delivery (ECD) versus vacuum-assisted delivery (VAD) during the second stage of labor among singleton gestations <34 weeks. Read More

N Engl J Med 2021 Apr;384(17):1635-1645

From the Division of Maternal-Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore.

Mol Reprod Dev 2021 Apr 26. Epub 2021 Apr 26.

Liggins Institute, The University of Auckland, Auckland, New Zealand.

Cytokines are important regulators of pregnancy and parturition. Aberrant expression of proinflammatory cytokines during pregnancy contributes towards preterm labor, pre-eclampsia, and gestational diabetes mellitus. The regulation of cytokine expression in human cells is highly complex, involving interactions between environment, transcription factors, and feedback mechanisms. Read More

Clin Anat 2021 Apr 27. Epub 2021 Apr 27.

Clinical Radiology & Imaging Science, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN, USA.

The inherent variable anatomy of the neonate and the uniquely-shaped maternal birth canal that is associated with the evolution of human bipedalism, constitute risk factors for neonatal brachial plexus palsy (NBPP). For example, those neonates with a prefixed brachial plexus (BP) are at greater risk of trauma due to lateral neck traction during delivery than those with a normal or postfixed BP. Compared to adults, neonates also have extremely large and heavy heads (high head:body ratio) set upon necks with muscles and ligaments that are weak and poorly developed. Read More

Tierarztl Prax Ausg G Grosstiere Nutztiere 2021 Apr 26;49(2):79-90. Epub 2021 Apr 26.

Klinik für Klauentiere, Veterinärmedizinische Fakultät der Universität Leipzig.

Objective: The aim of this study was to document the occurrence, history, and clinical findings of tibial neuropathy in German Holstein dairy cows in order to yield information regarding the importance and etiology of this disorder in dairy herds in Central Germany.

Materials And Methods: This prospective study was undertaken between January 2013 and October 2017 and included 88 German Holstein dairy cows with unilateral (UTN, n = 71) or bilateral (n = 17, BTN) tibial neuropathy. Data were collected from the history as well as the clinical and laboratory examinations. Read More

Am J Obstet Gynecol MFM 2021 Apr 23:100383. Epub 2021 Apr 23.

National Center for Fetal Medicine, St. Olavs hospital, Trondheim University Hospital, Trondheim, Norway; Department of Obstetrics and Gynecology, Stavanger University Hospital, Stavanger, Norway; Institute of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Background: Identifying predictive factors for a normal outcome at admission in the labor ward would be of value for planning labor care, timing interventions and in preventing labor dystocia. Clinical assessments of fetal head station and position at the start of labor have some predictive value but the value of ultrasound methods for this purpose has not been investigated. Studies using transperineal ultrasound before labor onset show possibilities of using these methods to predict outcome. Read More

BMC Womens Health 2021 Apr 22;21(1):172. Epub 2021 Apr 22.

Department of First Clinical Medical College, Shanxi Medical University, Taiyuan, 030001, Shanxi, China.

Background: The prevalence of stress urinary incontinence (SUI) in adult female in Taiyuan and what are the related risk factors are not clear. The aim of this study was to provide a basis for exploring the prevention and treatment of SUI in adult female in Taiyuan.

Methods: A voluntary online questionnaire was used to investigate adult female in the community and surrounding townships of Taiyuan. Read More

J Mol Histol 2021 Apr 19. Epub 2021 Apr 19.

Research Center of Abnormal Uterine Bleeding, Semnan University of Medical Sciences, Semnan, Iran.

SARS-CoV-2, the leading cause of COVID-19 pandemic, was detected for the first time in Wuhan. In this study, we investigated the potential undesirable maternal and feto-neonatal consequences of COVID-19, and the related pathophysiological alterations in mother, neonate, and especially in the placenta as a vital organ, were reviewed. Also, the possibility of vertical transmission of virus and placental abnormalities were evaluated. Read More

Vet Rec 2021 Apr 19:e300. Epub 2021 Apr 19.

Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow School of Veterinary Medicine, Glasgow, UK.

Background: Assistance at parturition in cattle is common. Although analgesia is commonly provided, its value in terms of welfare improvement is not known. Few previous studies include both parturition assistance and analgesic treatment status as well as appropriate control groups in a factorial design. Read More

Am J Obstet Gynecol 2021 Apr 15. Epub 2021 Apr 15.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.

Background: Insulin detemir, being used increasingly during pregnancy, may have pharmacological benefits compared to neutral protamine Hagedorn (NPH).

Objective: We evaluated the probability that treatment with insulin detemir compared to NPH reduces the risk for adverse neonatal outcome among individuals with Type 2 diabetes mellitus or overt type 2 (gestational diabetes diagnosis <20 weeks).

Study Design: We performed a multiclinic randomized controlled trial (09/2018 to 01/2020), which included singleton gestation with Type 2 diabetes or overt type 2 who sought obstetrical care ≤21 weeks. Read More

J Adv Vet Anim Res 2021 Mar 10;8(1):164-172. Epub 2021 Mar 10.

Faculty of Health and Environmental Sciences, Central University of Technology, Bloemfontein, South Africa.

Objectives: The objective of this study was to assess the relationship between pelvic measurements, namely pelvic height (PH), pelvic area (PA), and pelvic width, and linear body measurement traits, such as hindquarters width, rump length (RL), hip height (HH), body weight (BW), shoulder height, chest depth (CD), body length, and also calve birth weight (CBW) under different calving ease scores, namely no assistance, gently pull, and hard pull.

Material And Methods: A total of 51 first calf Sussex heifers at 24 months old, weighing approximately 440 ± 40.26 kg, were used for this study. Read More

BMJ 2021 04 14;373:n716. Epub 2021 Apr 14.

Department of Obstetrics and Gynaecology, Randers Regional Hospital, Randers, Denmark.

Objective: To determine whether discontinuing oxytocin stimulation in the active phase of induced labour is associated with lower caesarean section rates.

Design: International multicentre, double blind, randomised controlled trial.

Setting: Nine hospitals in Denmark and one in the Netherlands between 8 April 2016 and 30 June 2020. Read More

Turk J Med Sci 2021 Apr 12. Epub 2021 Apr 12.

Objective: This study aimed to evaluate the relationship between second- and third-trimester clavicle length and birth weight and shoulder dystocia.

Methods: This prospective observational study included 181 patients who presented to the Private Etlik Lokman Hekim Hospital for routine pregnancy visits between March 2019 and March 2020. In addition to routine pregnancy examinations, the patients also underwent ultrasonography twice at weeks 20-23 and 33-36 to determine the length of the fetal clavicle. Read More

Aust N Z J Obstet Gynaecol 2021 Apr 11. Epub 2021 Apr 11.

Department of Women's and Children's Health, University of Otago, Dunedin, New Zealand.

The interpretation of umbilical cord gases may not be straightforward following shoulder dystocia. We reviewed Perinatal and Maternal Mortality Review Committee data from New Zealand infants with moderate and severe neonatal encephalopathy (NE) for 2010-2017 inclusive. If one or more of: pH of ≤7. Read More

Front Endocrinol (Lausanne) 2021 26;12:640004. Epub 2021 Mar 26.

Faculty of Nursing and Health Sciences, Nord University, Bodø, Norway.

Objectives: It is uncertain whether the treatment of mild gestational diabetes mellitus (GDM) improves pregnancy outcomes. The aim of this systemic review and meta-analysis was to investigate the effect of mild GDM treatment on adverse pregnancy outcomes.

Methods: A comprehensive literature search was conducted on the databases of PubMed, Scopus, and Google Scholar to retrieve studies that compared interventions for the treatment of mild GDM with usual antenatal care. Read More