2,481 results match your criteria Abducens Nerve Palsy


Millard-Gubler Syndrome Associated with Cerebellar Ataxia in a Patient with Isolated Paramedian Pontine Infarction - A Rarely Observed Combination with a Benign Prognosis: A Case Report.

Case Rep Neurol 2021 Jan-Apr;13(1):239-245. Epub 2021 Apr 13.

Department of Neurology, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia.

Isolated pontine infarction accounts for 7% of all ischemic strokes. Millard-Gubler syndrome is a clinical syndrome which occurs following lesions involving the ventral portion of the caudal pons, resulting in classic clinical features such as ipsilateral abducens and facial nerve palsy and contralateral hemiparesis. We report the case of a 55-year-old male patient having presented to the Yehuleshet Specialty Clinic 6 years back with sudden-onset dysarthria and appendicular ataxia of 10 days duration. Read More

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Leptomeningeal Carcinomatosis With Optic Nerve Metastasis Secondary to Breast Cancer.

Cureus 2021 Mar 31;13(3):e14200. Epub 2021 Mar 31.

Department of Ophthalmology and Visual Science, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.

Leptomeningeal carcinomatosis (LC) and optic nerve metastasis are uncommon occurrences in breast cancer. We report a rare case of LC with optic nerve infiltration secondary to breast cancer. A 45-year-old lady who was a known case of treated right breast carcinoma six years ago presented with a blurring of vision in both eyes, floaters, and diplopia for one month. Read More

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[Prism-Induced Gaze Shift and Strabismus Treatment for Ocular Motility Disorders and Anomalous Head Posture].

Klin Monbl Augenheilkd 2021 Apr 30;238(4):474-477. Epub 2021 Apr 30.

Augenklinik, Kantonsspital St. Gallen, Schweiz.

Background: The therapeutic treatment of ocular motility disorders and anomalous head postures (AHP) is often challenging. We report our experience with prism use in these patients.

Patients And Methods: Retrospective case series of three patients with ocular motility disorders and associated AHP who were treated with prism correction. Read More

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[Nishida Extraocular Muscle Transposition Surgery for Abducens Nerve Palsy].

Klin Monbl Augenheilkd 2021 Apr 30;238(4):493-498. Epub 2021 Apr 30.

Augenklinik, Kantonsspital St. Gallen, Schweiz.

Background: Surgical treatment of abducens nerve palsy depends on the remaining function of the lateral rectus muscle. Vertical rectus transposition surgery is indicated if the attempted maximal abduction effort does not rotate the eye beyond the midline. After the first description more than 100 years ago, a variety of muscle transposition modifications have been suggested. Read More

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Gradenigo's and Vernet's syndrome in an adult man with Candida mastoiditis.

BMJ Case Rep 2021 Apr 27;14(4). Epub 2021 Apr 27.

Neurology, Baylor College of Medicine, Houston, Texas, USA.

The authors report a case of fungal otitis media complicated by extension of the infection into adjacent structures causing apical petrositis and subsequently involvement of the jugular foramen in a 71-year-old diabetic man. First described in 1907, Gradenigo's syndrome is a serious but rare clinical triad of acute otitis media, unilateral pain in the distribution of cranial nerve V (trigeminal) and ipsilateral cranial nerve VI (abducens) palsy that commonly presents without all three features and is therefore often missed. In this report, our patient was initially misdiagnosed as having a diabetic cranial neuropathy, and later he developed Vernet's syndrome. Read More

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Unilateral Abducens Nerve Palsy With Bilateral Retinitis: A Rare Presentation of Cat Scratch Disease.

J Neuroophthalmol 2021 Apr 14. Epub 2021 Apr 14.

Department of Ophthalmology (SL-N, TP, HL, OY), Kaplan Medical Center, Rehovot, Israel; Hadassah Medical School and the Hebrew University (HL, OY, DR, RG), Jerusalem, Israel; Department of Ophthalmology (DR), Shaare Zedek Medical Center, Jerusalem, Israel; and Department of Neurology (VS, RG), Kaplan Medical Center, Rehovot, Israel.

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IgG4-related hypophysitis.

Endocrine 2021 Apr 10. Epub 2021 Apr 10.

Department of Neurological Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Hypophysitis is a rare pituitary inflammatory disorder classified in different ways. Immunoglobulin G4-related disease (IgG4-RD), also a rare disease is a systemic fibro-inflammatory condition characterized by infiltration of tissue with IgG4-positive plasma cells; however prevalence of both of them probably is underestimated. In this paper, we present an Iranian patient with biopsy-proven IgG4-related hypophysitis and then review the clinical characteristics, laboratory, imaging, pathologic findings and therapeutic management as well as prognosis of 115 published cases of hypophysitis secondary to IgG4-related disease. Read More

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Acute-onset binocular diplopia in neurological unit: Aetiological factors and diagnostic assessment.

Acta Neurol Scand 2021 Mar 31. Epub 2021 Mar 31.

Department of Human Neurosciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.

Objectives: To investigate the aetiology of acute-onset binocular diplopia (AOBD) in neurological units and identify the key diagnostic procedures in this setting.

Materials And Methods: Clinico-demographic data from patients hospitalized for AOBD from 2008 to 2019 were retrospectively reviewed. AOBD due to an underlying neurological disorder known to cause diplopia was addressed as secondary diplopia. Read More

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Herpes zoster in an immunocompetent host with C6 dermatitis and abducens nerve palsy.

Can J Ophthalmol 2021 Mar 23. Epub 2021 Mar 23.

Medical Eye Specialists, Bozeman, Mont. Electronic address:

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[Outcomes after medial rectus recession and lateral rectus plication for abducens nerve palsy: A retrospective study].

J Fr Ophtalmol 2021 Mar 25. Epub 2021 Mar 25.

Service d'ophtalmologie, Centre Hospitalier Universitaire Régional de Bretonneau, 2, boulevard Tonnellé, 37044 Tours, France.

Background: Abducens nerve palsy (ANP) is the most common oculomotor palsy. This study aimed to evaluate the efficacy of medial rectus recession with lateral rectus plication in patients with unilateral acquired ANP and to describe the etiologies of this condition.

Methods: Thirty-one patients were included in this retrospective single-center study conducted between 2000 and 2019 at the university research hospital in Tours. Read More

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Abducens nerve palsy with associated retinal involvement secondary to rickettsia typhi infection.

J Ophthalmic Inflamm Infect 2021 Mar 22;11(1). Epub 2021 Mar 22.

Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, 5019, Monastir, Tunisia.

Objective: To report a case of abducens nerve palsy with associated retinal involvement due to rickettsia typhi infection.

Material And Methods: A single case report documented with multimodal imaging.

Results: A 18-year-old woman with a history of high-grade fever was initially diagnosed with typhoid fever and treated with fluoroquinolone. Read More

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Abducens nerve palsy treated by tethering the globe to the lateral orbital rim with a bone screw.

J AAPOS 2021 Feb 27. Epub 2021 Feb 27.

Department of Anesthesiology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi City, Taiwan; Department of Biotechnology, Asia University, Taichung City, Taiwan.

We report the case of a 38-year-old man with abducens palsy following a traumatic skull injury who failed multiple strabismus surgeries. A suture-armed 5 mm micro bone screw was placed on the anterior face of the lateral orbital rim and used to tether and abduct the globe. The patient remained orthotropic in primary position 12 months postoperatively. Read More

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February 2021

50 Years Ago in TheJournalofPediatrics: Sixth Cranial Nerve Palsy in the Neonate.

J Pediatr 2021 03;230:125

Department of Pediatric Research, University of Oslo, Oslo, Norway; Ann and Robert H. Lurie Children's Hospital of Chicago; Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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Fascicular Sixth Nerve Palsy as a Presenting Sign of Metastatic Ovarian Carcinoma.

J Neuroophthalmol 2021 Feb 19. Epub 2021 Feb 19.

Baylor College of Medicine (NR, AGL), Houston, Texas; Department of Ophthalmology (PM, AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; The Houston Methodist Research Institute (AGL), Houston Methodist Hospital, Houston, Texas; Departments of Ophthalmology (AGL), Neurology, and Neurosurgery, Weill Cornell Medicine, New York, New York; and Department of Ophthalmology (AGL), University of Texas Medical Branch, Galveston, Texas.

Abstract: The most common etiology of an isolated abducens nerve palsy in an older adult with vasculopathic risk factors is presumed microvascular ischemia. Because the diagnosis of microvascular ischemia in this setting would not alter patient management, there is debate as to whether further workup is warranted under these circumstances. In this report, we describe a fascicular sixth nerve palsy as the initial presenting sign of metastatic ovarian carcinoma, and we highlight the importance of considering additional workup in select cases of isolated abducens nerve palsies. Read More

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February 2021

Transient Bilateral Sixth Nerve Palsy: A Rare Sequela of Head Trauma.

Cureus 2021 Jan 20;13(1):e12805. Epub 2021 Jan 20.

Emergency, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, SAU.

Sixth cranial nerve palsy is uncommon but a well-recognized consequence of head trauma. Although few cases documented traumatic persistent bilateral sixth nerve palsy, a transient episode is extremely rare and not reported before. We report an unusual case of transient bilateral abducens nerve palsy after minor head trauma, which was completely resolved without any intervention after 20 min. Read More

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January 2021

Outcomes of modified vertical rectus belly transposition versus augmented superior rectus transposition for chronic abducens nerve palsy.

J AAPOS 2021 Feb 20. Epub 2021 Feb 20.

Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Shanghai Medical School, Fudan University, Shanghai, China; NHC Key Laboratory of Myopia, Fudan University, Shanghai, China; Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China. Electronic address:

Purpose: To compare the surgical outcomes of modified vertical rectus belly transposition (mVRBT) and medial rectus recession (MRc) versus augmented superior rectus transposition (aSRT) and MRc in Chinese patients with chronic abducens nerve palsy.

Methods: The medical records of patients with chronic abducens nerve palsy who underwent mVRBT/MRc or aSRT/MRc were retrospectively reviewed. Pre- and postoperative deviation in primary position, pre- and postoperative abduction limitation, and complications were recorded. Read More

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February 2021

Minimal anterior and posterior combined transpetrosal approach for large petroclival meningiomas.

J Neurosurg 2021 Feb 19:1-10. Epub 2021 Feb 19.

Objective: Petroclival meningiomas (PCMs) remain difficult to remove, and radical tumor resection continues to pose a relatively high risk of neurological morbidity in patients with these lesions because of the proximity of the tumor to neurovascular structures. The anterior and posterior combined (APC) transpetrosal approach allows resection of a large petroclival lesion with minimal retraction of the temporal lobe. However, this approach is thought to be complex and time-consuming. Read More

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February 2021

Isolated abducens nerve palsy - A rare clinical presentation in dengue haemorrhagic fever.

Trop Doct 2021 Feb 18:49475520983643. Epub 2021 Feb 18.

Assistant Professor, Department of Ophthalmology, Midnapore Medical College & Hospital, Kolkata, India.

Dengue fever is the most prevalent flavivirus infection in tropical and subtropical areas of the world. It is transmitted by the haematophagous mosquito Aedes aegypti, and it manifests clinically as classical dengue fever, dengue haemorrhagic fever and dengue shock syndrome. Rarely, dengue can be associated with neurophthalmic manifestations. Read More

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February 2021

Cranial Nerve VI Palsy as Presenting Sign of Previously Undiagnosed Metastatic Prostate Adenocarcinoma to the Clivus.

Biomed Hub 2020 Sep-Dec;5(3):210-213. Epub 2020 Oct 6.

Department of Otorhinolaryngology - Head & Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.

Prostate adenocarcinoma is the most common malignancy in males in the United States and is typically highly treatable. Herein we present a case report of a male with a history of prostate adenocarcinoma previously managed with definitive radiation therapy who presented with sudden onset diplopia and examination consistent with an abducens palsy. He was ultimately found to have prostate adenocarcinoma metastatic to the clivus causing cranial neuropathy, and was referred for systemic chemotherapy and palliative Cyberknife stereotactic radiosurgery. Read More

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October 2020

Contralateral Transmaxillary Approach for Resection of Chondrosarcoma of the Petrous Apex: A Case Report.

Ear Nose Throat J 2021 Feb 9:145561320982161. Epub 2021 Feb 9.

Department of Otolaryngology-Head and Neck Surgery, 5631West Virginia University, Morgantown, WV, USA.

Background: Deep location and neurovascular structures make access to lesions of the petrous apex a significant challenge. A novel approach for these tumors is the contralateral transmaxillary approach.

Clinical Presentation: A 31-year-old male was evaluated for left abducens nerve palsy. Read More

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February 2021

Differences in surgical outcome between petroclival meningioma and anterior petrous meningioma.

Acta Neurochir (Wien) 2021 Jun 8;163(6):1697-1704. Epub 2021 Feb 8.

Department of Neurosurgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background: Petroclival meningiomas (PC MNGs) and anterior petrous meningiomas (AP MNGs) have similar locations. However, these are different tumors clearly divided by the trigeminal nerve. There has never been a study on the comparison of the surgical outcomes of these two meningiomas. Read More

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Cranial nerve VI palsy (Abducens nerve).

Dis Mon 2021 May 2;67(5):101133. Epub 2021 Feb 2.

Cook County Health and Hospital Systems, United States. Electronic address:

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Location of the abducens nerve stretched by a tortuous vertebrobasilar artery in trigeminal neuralgia.

Acta Neurochir (Wien) 2021 04 4;163(4):1027-1036. Epub 2021 Feb 4.

Division of Neurosurgery, Duke University Medical Center, Durham, NC, USA.

Background: Trigeminal neuralgia (TGN) caused by the vertebrobasilar artery (VBA) is uncommon. The abducens nerve root is frequently dislocated by a tortuous VBA near the trigeminal nerve root. This unusual location of the root is not well known. Read More

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Diplopia in a Child: Gradenigo Syndrome Is an Unforgettable Disease.

Ear Nose Throat J 2021 Jan 28:145561321989459. Epub 2021 Jan 28.

Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan.

Gradenigo syndrome is a clinical triad of abducens nerve palsy, retro-orbital pain (trigeminal ganglionitis), and chronic otorrhea (otitis media). The etiology of Gradenigo syndrome results from apical petrositis secondary to suppurative otitis media. Although apical petrositis has gradually become uncommon in modern society due to the widespread use of antibiotics, Gradenigo syndrome should be considered in the differential diagnosis of a child's diplopia. Read More

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January 2021

Magnetic resonance imaging features of COVID-19-related cranial nerve lesions.

J Neurovirol 2021 02 18;27(1):171-177. Epub 2021 Jan 18.

NEUROCOVID-RIO Group-Research Group On Neurological Syndromes Associated With SARS-CoV-2, Rio de Janeiro, Brazil.

The complete features of the neurological complications of coronavirus disease 2019 (COVID-19) still need to be elucidated, including associated cranial nerve involvement. In the present study we describe cranial nerve lesions seen in magnetic resonance imaging (MRI) of six cases of confirmed COVID-19, involving the olfactory bulb, optic nerve, abducens nerve, and facial nerve. Cranial nerve involvement was associated with COVID-19, but whether by direct viral invasion or autoimmunity needs to be clarified. Read More

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February 2021

Two cases of benign abducens nerve palsy in children and their long-term follow-up.

J Int Med Res 2021 Jan;49(1):300060520986702

Department of Neurology, Children's Hospital of Soochow University, Suzhou, Jiangsu Province, China.

Our aim was to explore the clinical characteristics and diagnostic methods of benign abducens nerve palsy in children. The clinical and laboratory characteristics, treatment approach, and prognosis of two children with benign abducens nerve palsy were retrospectively evaluated. The main clinical symptoms of the two children were limited binocular movement accompanied by double vision, and the positive physical signs were limited binocular abduction accompanied by diplopia. Read More

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January 2021

Isolated abducens nerve palsy following temporal bone fracture in a child.

Taiwan J Ophthalmol 2020 Oct-Dec;10(4):306-308. Epub 2020 Feb 19.

Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.

Temporal bone fractures are often associated with damage to middle or inner ear structures, facial nerve, and cerebrospinal fluid (CSF) leak, and rarely with abducens nerve palsy. Isolated abducens nerve palsy is not known to occur following temporal bone fracture and is most commonly associated with concurrent facial nerve injury. We report a case of an 11-year-old girl who presented with isolated right abducens nerve palsy following head trauma. Read More

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February 2020

Sphenoid wing dural arteriovenous fistula: A case report and literature review.

Surg Neurol Int 2020 16;11:438. Epub 2020 Dec 16.

Department of Neurosurgery, Japan Organization of Occupational Health and Safety Toyama Rousai Hospital, Toyama, Japan.

Background: Sphenoid wing dural arteriovenous fistula (SWDAVF) is rare that is typically fed by middle meningeal artery feeders and that drain through the sphenoparietal sinus or middle cerebral vein. Here, we report a case of SWDAVF treated by coils placed in the venous aneurysm through the contralateral cavernous sinus (CS).

Case Description: A 37-year-old woman was admitted to our hospital with headache and bilateral oculomotor nerve palsy. Read More

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December 2020

Nelson Syndrome: Clival Invasion of Corticotroph Pituitary Adenoma Resulting in Alternating Sixth Nerve Palsies.

J Neuroophthalmol 2021 Mar;41(1):114-118

Division of Neuro-Ophthalmology (VPD, KAAD, BKC), Massachusetts Eye and Ear/Harvard Medical School, Boston, Massachusetts; and Departments of Radiology (OR), Pathology (SNC), and Neurology (BKC), Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts.

Abstract: A 44-year-old woman presented with 2 painful and self-limited episodes of binocular horizontal diplopia within 1 year that at the beginning were thought to be secondary to microvascular insult. Her medical history was significant for Cushing syndrome status post transsphenoidal resection with bilateral adrenalectomy 4 years prior, hypertension, and diabetes mellitus. Neuro-ophthalmic evaluation was significant for left abduction deficit and incomitant esotropia consistent with left abducens nerve palsy. Read More

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