4,185 results match your criteria Abducens Nerve Palsy


Scedosporium apiospermum invasive sinusitis presenting as extradural abscess.

Eur Ann Otorhinolaryngol Head Neck Dis 2018 Dec 4. Epub 2018 Dec 4.

Département d'otorhinolaryngologie/chirurgie cervico-faciale/chirurgie de la base du crâne, université Paris-Diderot, hôpital Lariboisière, AP-HP, Paris, France.

Introduction: Chronic invasive fungal rhinosinusitis (CIFR) is a rare entity generally observed in immunodepressed subjects. The pathogen most frequently identified is Aspergillus spp. Imaging generally reveals invasive pseudoneoplastic features. Read More

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December 2018

Vocal Cord Palsy as a Complication of Epidural Anaesthesia.

Case Rep Otolaryngol 2018 25;2018:6543656. Epub 2018 Oct 25.

Department of Otorhinolaryngology Head & Neck Surgery, Galway University Hospital, Galway, Ireland.

Cranial nerve palsy is a rare but recognised complication of epidural anaesthesia, most commonly presenting as diplopia secondary to abducens nerve palsy. While upper cranial nerve palsies have been documented on numerous occasions, lower cranial nerve palsies, including recurrent laryngeal nerve palsy, are exceedingly rare. This case describes a 37-year-old female who, following epidural anaesthesia for spontaneous vaginal delivery of her first child, presented with dysphonia. Read More

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October 2018
3 Reads

Chondrosarcoma in the Petrous Apex: Case Report and Review.

J Neurol Surg Rep 2018 Oct 18;79(4):e83-e87. Epub 2018 Oct 18.

Division of Neurosurgery, Department of Surgery, The Ottawa Hospital, Ottawa, Canada.

 Surgical treatment of petrous apex chondrosarcoma is challenging due to the location of the tumor. Using an endoscopic technique for tumor resection is favored since it provides a minimally invasive approach.  A 57 years old female was admitted for acute onset of left abducens nerve palsy and occasional headache mainly on the left side of the retro-orbital area with some radiation to the left occiput. Read More

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October 2018
3 Reads

Suboccipital Lateral Approach for Resection of Cerebellopontine Angle Meningioma: Operative Video and Technical Nuances.

J Neurol Surg B Skull Base 2018 Dec 9;79(Suppl 5):S397-S398. Epub 2018 Oct 9.

Department of Neurosurgery, Hospital Beneficência Portuguesa de São Paulo, Institute of Neurological Science of São Paulo, Bela Vista, São Paulo, Brasil.

We present the case of a 34-year-old woman, who presented to our department with a 4 months history of dizziness, hearing loss, and tinnitus on the right side. MRI (magnetic resonance imaging) scan demonstrated a large extra-axial lesion, suggestive of a meningioma, with dural attachments to the petrosal bone surface and tentorium, closely related with the trigeminal, abducens, facial, vestibulocochlear, and lower cranial nerves in the right side. Treatment options were discussed with the patient, and surgical resection was selected to remove the lesion, and decompress the cranial nerves and brainstem. Read More

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December 2018
1 Read

Retrosigmoid Approach to the Posterior Fossa Trigeminal Schwannoma.

J Neurol Surg B Skull Base 2018 Dec 25;79(Suppl 5):S393-S394. Epub 2018 Sep 25.

Department of Neurosurgery, University of Colorado, Aurora, Colorado, United States.

We present a case of a posterior fossa trigeminal schwannoma in a 31-year-old gentleman. Preoperative symptomatology included headaches and dizziness of 6 months in duration. Trigeminal schwannomas isolated to the posterior fossa, not extending into Meckel's Cave, may be adequately resected via a retrosigmoid approach. Read More

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December 2018
4 Reads

Absent cochlear and abducens nerves in a patient with Duane retraction syndrome.

Neurol Sci 2018 Oct 30. Epub 2018 Oct 30.

Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam, Gyeonggi-do, 13620, South Korea.

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October 2018

[Classification of Clinical Syndromes Associated with Skull-Base Metastasis in the MR Era].

No Shinkei Geka 2018 Oct;46(10):865-873

Division of Neurosurgery, Shizuoka Cancer Center.

Background: Skull-base metastases frequently cause progressive ipsilateral disturbances of cranial nerves or pain, resulting in poor quality of life in patients with cancer. Magnetic resonance(MR)imaging is the method to detect skull-base metastases, which demonstrates focal lesions of low-intensity signal and enhancement on T1-weighted MR images.

Methods: We reviewed clinical data and MR images from 127 patients with skull-base metastases diagnosed at Shizuoka Cancer Center Hospital between August 2012 and November 2017. Read More

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October 2018
7 Reads

Tuberous sclerosis complex: a clinical case with multiple ophthalmological manifestations.

BMJ Case Rep 2018 Oct 25;2018. Epub 2018 Oct 25.

Ophthalmology, Hospital Pedro Hispano, Matosinhos, Portugal.

The tuberous sclerosis complex is a rare disease, with autosomal dominant transmission, with multisystemic involvement including ophthalmologic. Retinal hamartomas and retinal achromic patch are the most frequent ocular findings. Other ophthalmic signs and symptoms are relatively rare in this disease. Read More

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October 2018
2 Reads

Adjustable Posterior Fixation Suture Technique in Adjustable Superior Rectus Transposition.

J Binocul Vis Ocul Motil 2018 Oct-Dec;68(4):154-155. Epub 2018 Oct 26.

a Jules Stein Eye Institute and Department of Ophthalmology , University of California , Los Angeles , California.

Background: Recently, the superior rectus transposition has been widely adopted for the treatment of complete abducens palsy and Duane syndrome. This procedure is useful in that there is a decreased risk of anterior segment ischemia compared to complete vertical rectus transposition, possibly decreased incidence of postoperative-induced vertical deviations than complete vertical rectus transposition, and improvement in abduction compared to simple medial rectus recession. One difficulty with this procedure is the lack of adjustability in most patients. Read More

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October 2018
4 Reads

Multiple cranial nerve palsies in immunodeficiency subtype of Burkitt lymphoma.

J Community Hosp Intern Med Perspect 2018 15;8(5):303-306. Epub 2018 Oct 15.

Department of Hematology and Oncology, Saint Agnes Hospital, Baltimore, MD, USA.

Burkitt lymphoma is a late complication of HIV, and bilateral cranial nerve palsies are extremely rare in patients with AIDS. A twenty year old Caucasian male with known congenital HIV who had been non-adherent with anti-retroviral therapy presented with multiple cranial nerve palsies and was eventually diagnosed with Burkitt lymphoma. Before chemotherapy, he was started on radiation therapy to the brain, meninges, and base of skull with the intent of improving cranial nerve palsies and preventing further neurological sequelae since the cranial nerve palsies were dense and there was concern that intrathecal chemotherapy would have less penetration than radiation. Read More

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October 2018

Bilateral optic perineuritis and left abducens nerve palsy in a toddler.

Can J Ophthalmol 2018 Oct 1;53(5):e211-e212. Epub 2018 Feb 1.

School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia. Electronic address:

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October 2018

Neural Plasticity Following Surgical Correction of Strabismus in Monkeys.

Invest Ophthalmol Vis Sci 2018 Oct;59(12):5011-5021

College of Optometry, University of Houston, Houston, Texas, United States.

Purpose: Although widely practiced, surgical treatment of strabismus has varying levels of success and permanence. In this study we investigated adaptive responses within the brain and the extraocular muscles (EOM) that occur following surgery and therefore determine long-term success of the treatment.

Methods: Single cell responses were collected from cells in the oculomotor and abducens nuclei before and after two monkeys (M1, M2) with exotropia (divergent strabismus) underwent a strabismus correction surgery that involved weakening of the lateral rectus (LR) and strengthening of the medial rectus (MR) muscle of one eye. Read More

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October 2018
10 Reads

Abducens nerve palsy in pre eclampsia : case report.

Tunis Med 2018 Jan;96(1):76-79

Cranial nerves palsy associated with preeclampsia is reported in literature. Facial and abducens palsies were the most nerve disorders described. Only eleven cases have been reported in the literature. Read More

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January 2018
1 Read

Cranial nerve palsies due to incidental durotomy in lumbar Spine surgery: a case report.

Br J Neurosurg 2018 Oct 13:1-3. Epub 2018 Oct 13.

a CENSE-Spine, Department of Neurosurgery , Aarhus University Hospital , Aarhus , Denmark.

We present a 65-year old man who underwent a partial laminectomy at L4. During surgery an incidental durotomy (ID) appeared. Postoperatively he developed cranial nerve palsies. Read More

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October 2018
7 Reads

Meckel's Cave Epidermoid Cyst Presenting as Multiple Cranial Nerve Deficits Due to Indirect Tumoral Compression of the Cavernous Sinus: A Case Report and Literature Review.

World Neurosurg 2018 Oct 8. Epub 2018 Oct 8.

Carilion Clinic, Section of Neurosurgery, 1906 Belleview Ave, Roanoke, VA 24014, USA; Virginia Tech Carilion School of Medicine, 2 Riverside Circle, Roanoke, VA 24016, USA; Virginia Tech School of Neuroscience, 300 Turner Street NW, Blacksburg, VA 24061, USA. Electronic address:

Background: Epidermoid cysts in Meckel's cave are exceedingly rare. Since 1971, only 17 cases have been reported in the literature with the majority of patients presenting with trigeminal hypesthesia. However, outgrowth of these lesions from Meckel's cave can rarely lead to compression of the proximate cavernous sinus and the neurovascular structures contained within. Read More

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October 2018
2 Reads

Dual-Augmented Transposition of Vertical Recti in Chronic Abducens Palsy.

Authors:
Mohamed F Farid

Am J Ophthalmol 2019 Jan 9;197:59-64. Epub 2018 Oct 9.

Department of Ophthalmology, Benha Faculty of Medicine, Benha University, Benha, Egypt; Department of Ophthalmology, Benha University Hospital, Benha, Egypt. Electronic address:

Purpose: To report the results of dual augmentation of vertical rectus muscle transposition (VRT) in the treatment of chronic sixth nerve palsy.

Design: Retrospective case series.

Methods: This is a retrospective review of medical records of patients with chronic sixth nerve palsy who underwent dual augmented VRT with or without medial rectus (MR) recession from 2013 to 2016. Read More

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January 2019
6 Reads
3.870 Impact Factor

ABC om - Wernickes encefalopati.

Lakartidningen 2017 09 12;114. Epub 2017 Sep 12.

Umea Universitet Medicinska fakulteten - Institutionen för klinisk vetenskap - psykiatri, Sunderby Forskningsenhet Umea, Sweden Umea Universitet Medicinska fakulteten - Institutionen för klinisk vetenskap - psykiatri, Sunderby Forskningsenhet Umea, Sweden.

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September 2017
1 Read

Relationship between Abducens Nerve Palsy and Local Hematoma in a Case Series of Ruptured Vertebral Artery Dissecting Aneurysm.

Asian J Neurosurg 2018 Jul-Sep;13(3):572-576

Department of Neurosurgery, Kariya Toyota General Hospital, Kariya, Japan.

Background: Abducens nerve palsy associated with subarachnoid hemorrhage (SAH) has rarely been reported. Its frequency, mechanism of palsy, association with aneurysmal location, and clinical course are poorly described. The purpose of our study was to evaluate patients with abducens nerve palsy caused by SAH occurring from ruptured vertebral artery (VA) dissecting aneurysm and to find aneurysmal location using initial computed tomography (CT) and its association with clinically detected cranial nerve palsy. Read More

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October 2018
2 Reads

Isolated Abducens Nerve Palsy Associated with a Ruptured Posterior Inferior Cerebellar Artery Aneurysm: A Rare Neurological Finding.

World Neurosurg 2018 Sep 25. Epub 2018 Sep 25.

Department of Neurosurgery, Rutgers: Robert Wood Johnson Medical School, New Brunswick, NJ.

Isolated abducens nerve palsy can be the presenting sign of a ruptured PICA aneurysm. Few cases have been reported in the literature. In the majority of cases, the CN VI resolved following microsurgical clipping. Read More

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September 2018
4 Reads

The Eustachian Tube as a Landmark for Early Identification of the Abducens Nerve During Endonasal Transclival Approaches.

Oper Neurosurg (Hagerstown) 2018 Sep 25. Epub 2018 Sep 25.

Department of Neurological Surgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio.

Background: Expanded endonasal approaches have the potential to injure the abducens nerve (cranial nerve [CN] VI). The nerve's root entry zone (REZ) and cisternal segment (CS) are particularly prone to injury during the clivus resection and dural incision of transclival approaches.

Objective: To investigate the role of the eustachian tube (ET) as a surgical landmark for the REZ and CS of CN VI. Read More

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September 2018
6 Reads

Surgical Treatment of Cavernous Sinus Lesion in Patients with Nonfunctioning Pituitary Adenomas via the Endoscopic Endonasal Approach.

J Neurol Surg B Skull Base 2018 Oct 16;79(Suppl 4):S311-S315. Epub 2018 Jul 16.

Department of Neurosurgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

 The main purpose of this article is to assess the effectiveness and safety of surgery via the endoscopic endonasal approach (EEA) for cavernous sinus (CS) lesion in patients with nonfunctioning pituitary adenomas (NFPA).  Retrospective study.  Keio University Hospital. Read More

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October 2018
1 Read

Novel method of intraoperative ocular movement monitoring using a piezoelectric device: experimental study of ocular motor nerve activating piezoelectric potentials (OMNAPP) and clinical application for skull base surgeries.

Neurosurg Rev 2018 Sep 12. Epub 2018 Sep 12.

Department of Neurosurgery, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka, 830-0011, Japan.

Intraoperative monitoring systems that utilize various evoked potentials for the detection and/or preservation of cranial nerves have become increasingly common due to recent technical and commercial developments, particularly during skull base surgeries. We established a novel system for the intraoperative monitoring of the extraocular motor nerves (eOMNs) using a piezoelectric device capable of detecting imperceptible vibrations induced by ocular movement, with sensors placed on the eyelids alone. We first evaluated the efficacy and reliability of this device for the intraoperative monitoring of eOMNs in two Beagle dogs. Read More

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September 2018

Supratotal Resection of Residual Clival Chordoma With Combined Endoscopic Endonasal and Contralateral Transmaxillary Approaches: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Sep 4. Epub 2018 Sep 4.

Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

The optimal treatment for skull base chordomas is gross total resection followed by radiotherapy and not radiation of partially resected tumors. Supratotal resection, defined as removal beyond all involved bone and dura, is ideal but difficult to achieve. In this video, we present the case of a 37-yr-old man with new onset of progressive cranial nerve sixth palsy and a skull base lesion compatible with clival chordoma. Read More

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September 2018
1 Read

Epidural blood patch treatment of diplopia that developed after headache resolution in a patient with spontaneous intracranial hypotension.

J Dent Anesth Pain Med 2018 Aug 28;18(4):255-259. Epub 2018 Aug 28.

Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Sudden headache onset may rarely be caused by spontaneous intracranial hypotension (SIH). Other associated symptoms in patients with SIH are nausea, vomiting, vertigo, hearing alteration, and visual disturbance. This case report describes a 43-year-old female diagnosed with SIH who developed diplopia after resolution of an abrupt-onset headache, which was managed with conservative treatments, including bed rest and hydration. Read More

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Application of SRT plus MR recession in supra-maximal esotropia from chronic sixth nerve palsy.

Graefes Arch Clin Exp Ophthalmol 2018 Sep 4. Epub 2018 Sep 4.

Department of Ophthalmology & Visual Science, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

Background: To investigate prognostic factors in patients with augmented superior rectus transposition (SRT) for sixth nerve palsy.

Methods: Thirteen patients who were diagnosed with sixth nerve palsy and underwent augmented SRT between January 2015 and February 2017 in EENT Hospital of Fudan University were reviewed retrospectively. Data including age, sex, etiology of the abducens nerve palsy, degree of pre- and postoperative deviation in the primary position, pre- and postoperative abduction deficit, any induced vertical or torsional deviations, reoperations, and other complications was collected. Read More

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September 2018
6 Reads
1.910 Impact Factor

Typhoid fever with isolated left lateral rectus palsy.

BMJ Case Rep 2018 Sep 4;2018. Epub 2018 Sep 4.

Oxford University Clinical Research Unit, Patan Hospital, Lalitpur, Province - 3, Nepal.

A 17-year-old young woman presented to Patan Hospital, Kathmandu, Nepal, with high-grade fever and headache for 4 days and non-projectile vomiting for 1 day. She also had blurred vision with dizziness on and off. There was no abnormal physical finding. Read More

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September 2018
8 Reads

Acute Transient Sixth Nerve Palsy in Chediak-Higashi Syndrome.

J Pediatr Ophthalmol Strabismus 2018 Aug 29;55:e22-e25. Epub 2018 Aug 29.

Neurologic disorders in Chediak-Higashi syndrome are usually late presentations and also may manifest long after bone marrow stem cell transplantation. To the authors' knowledge, transient neurological deficit has not been reported yet. They describe a 6-year-old boy with Chediak-Higashi syndrome in the accelerated phase who presented with transient sixth nerve palsy. Read More

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August 2018
8 Reads

Abducens Nerve Palsy as Initial Presentation of Multiple Myeloma and Intracranial Plasmacytoma.

J Clin Med 2018 Sep 3;7(9). Epub 2018 Sep 3.

College of Medicine, University of Kentucky, Lexington, KY 40506, USA.

Central Nervous System (CNS) involvement in multiple myeloma and/or multifocal solitary plasmacytoma is rare. Although they are unique entities, multiple myeloma (MM) and plasmacytoma represent a spectrum of plasma cell neoplastic diseases that can sometimes occur concurrently. Plasmacytomas very often present as late-stage sequelae of MM. Read More

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September 2018
7 Reads

Bilateral oculomotor ocular neuromyotonia: a case report.

BMC Neurol 2018 Sep 3;18(1):137. Epub 2018 Sep 3.

Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Bangkok, 10400, Thailand.

Background: Ocular neuromyotonia (ONM) is characterized by episodic diplopia, which is usually triggered by prolonged eccentric gaze of the affected extraocular muscles. The spell is characterized by involuntary, occasionally painful, sustained contraction of one or more extraocular muscles innervated by the oculomotor, trochlear, or abducens nerve. ONM usually occurs as a late consequence of radiotherapy around the parasellar area, although idiopathic cases have been reported. Read More

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September 2018
7 Reads

Murine typhus associated abducens nerve palsy.

Kaohsiung J Med Sci 2018 09 2;34(9):537-538. Epub 2018 Mar 2.

College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Infection Control Office and Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:

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September 2018
2 Reads

Persistent isolated abducens nerve palsy in a successfully embolized low-flow carotid cavernous fistula.

Clin Exp Ophthalmol 2018 Aug 31. Epub 2018 Aug 31.

South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

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August 2018
11 Reads
1.953 Impact Factor

Isolated Oculomotor and Abducens Nerve Palsies as Initial Presentation of Cavernous Sinus Tuberculoma: Case Report and Literature Review.

World Neurosurg 2018 Sep 2;117:413-418. Epub 2018 Jul 2.

Department of Neurology, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran. Electronic address:

Background: Central nervous system tuberculoma is the most severe manifestation of extrapulmonary tuberculosis with high mortality. Cavernous sinus tuberculoma (CST) is a very rare central nervous system tuberculoma with few cases reported in the literature.

Case Description: A 57-year-old woman was admitted to our clinic with acute diplopia and headache limited to the right side. Read More

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September 2018
12 Reads

Correction to: Unilateral duplicated abducens nerve coursing through both the sphenopetroclival venous gulf and cavernous sinus: a case report.

Surg Radiol Anat 2018 11;40(11):1327

Department of Anatomy and Organogenesis, Faculty of Medicine, University of Picardie Jules Verne, 3 rue des Louvels, 80036, Amiens, Somme, France.

In the Original Publication of the article, one of the references was missed to include. This reference and the text citation are given below. Read More

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November 2018

Giant cranionasal epithelioid haemangioendothelioma with invasive growth pattern mimicking a skull base chondrosarcoma.

Contemp Oncol (Pozn) 2018 13;22(2):118-123. Epub 2018 Jun 13.

Hospital Vital Álvarez Buylla, Spain.

Epithelioid haemangioendothelioma (EHE) is a rare low-grade vascular neoplasm that is composed of mostly epithelioid cells. EHE may arise as a solitary tumour or in the form of multiple body lesions, and commonly occurs in soft tissues, liver, pleura, lung, peritoneum, lymph nodes, breast, and many other sites. EHE in the cranionasal region is extremely rare. Read More

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June 2018
0.220 Impact Factor

High-Flow Bypass with Internal Carotid Artery to Middle Cerebral Artery Bypass Using Radial Artery Graft Through the Supramandibular-Subzygomatic Route for Giant Internal Carotid Aneurysm: Technical Case Report.

World Neurosurg 2018 Dec 24;120:138-142. Epub 2018 Aug 24.

Division of Neurosurgery, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Tottori, Japan.

Background: A unique case of an internal carotid artery (ICA) giant aneurysm treated by high-flow bypass is presented. This patient had some anatomic variations in the neck region that posed problems for the high-flow bypass, and a new approach to address them is presented.

Case Description: A 55-year woman presented with diplopia, abducens nerve palsy, severe headache, and disordered consciousness. Read More

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December 2018
1 Read

Validity and reliability of the Ocular Motor Nerve Palsy Scale.

Neural Regen Res 2018 Oct;13(10):1851-1856

Ocular Motility Disorder Treatment & Rehabilitation Center, Department of Acupuncture, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.

Objective and accurate assessment of the degree of ocular motor nerve palsy is helpful not only in the evaluation of prognosis, but also for the screening of treatment methods. However, there is currently no comprehensive measure of its severity. In this study, we designed the Ocular Motor Nerve Palsy Scale and investigated its validity and reliability. Read More

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October 2018
10 Reads

Optical analysis of functional development of the facial motor nucleus in the embryonic rat brainstem.

Eur J Neurosci 2018 Nov 9;48(10):3273-3287. Epub 2018 Sep 9.

Department of Health and Nutrition Sciences, Faculty of Human Health, Komazawa Women's University, Tokyo, Japan.

Facial motor neurons of the rat embryo are first generated in rhombomere 4 and then migrate in the caudo-ventral direction. This migration forms a unique axonal trajectory called the genu, a loop of facial motor axons around the abducens nucleus. It is still unclear when and how this unique structure is functionally established during ontogenesis. Read More

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November 2018
1 Read

Primary Sphenoidal Sinus Lymphoma with Initial Presentation as Unilateral Abducens Nerve Palsy Symptom.

Case Rep Neurol Med 2018 9;2018:5305963. Epub 2018 Jul 9.

Department of Neurology, The Second Hospital of Jilin University, China.

A 48-year-old man presented with 3 days of mild horizontal diplopia in the left direction, followed by the onset of headache 17 days later. A physical examination revealed isolated left abducens nerve palsy. Head computed tomography (CT) and magnetic resonance imaging (MRI) scans revealed soft-tissue density neoplasms that occupied the sphenoidal sinus and further invaded to destroy the clivus. Read More

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July 2018
21 Reads

Protocadherin-Mediated Cell Repulsion Controls the Central Topography and Efferent Projections of the Abducens Nucleus.

Cell Rep 2018 Aug;24(6):1562-1572

Division of Molecular and Developmental Biology, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan; Department of Genetics, Graduate University for Advanced Studies (SOKENDAI), 1111 Yata, Mishima, Shizuoka 411-8540, Japan. Electronic address:

Cranial motor nuclei in the brainstem innervate diverse types of head and neck muscles. Failure in establishing these neuromuscular connections causes congenital cranial dysinnervation disorders (CCDDs) characterized by abnormal craniofacial movements. However, mechanisms that link cranial motor nuclei to target muscles are poorly understood at the molecular level. Read More

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August 2018
7 Reads

Comparison of Clinical and Radiological Findings between Congenital Orbital Fibrosis and Congenital Fibrosis of the Extraocular Muscles.

Curr Eye Res 2018 Dec 6;43(12):1471-1476. Epub 2018 Aug 6.

a Department of Ophthalmology , Seoul National University College of Medicine, Seoul National University Bundang Hospital , Seongnam , Korea.

Purpose/Aims: To compare the clinical and radiological findings of the two rare entities of congenital orbital fibrosis and congenital fibrosis of the extraocular muscles (CFEOM). Materials Methods: Clinical characteristics and magnetic resonance imaging (MRI) findings of three congenital orbital fibrosis patients were analyzed and compared to 13 CFEOM patients. Results: In all three patients with congenital orbital fibrosis, unilateral EOM limitation and enophthalmos were found with a retrobulbar infiltrating mass and normal oculomotor and abducens nerves on MRI. Read More

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December 2018

Magnetic resonance imaging of developmental facial paresis: a spectrum of complex anomalies.

Neuroradiology 2018 Oct 3;60(10):1053-1061. Epub 2018 Aug 3.

Clinical Genetics Department, Human Genetics and Genome Research Division, National Research Centre, Cairo, Egypt.

Purpose: Despite its clinical implications, the MRI features of developmental facial paresis (DFP) were described in a few case reports. This study aims to describe MRI features of DFP in relation to the embryological development with a proposed radiological new grading system.

Methods: The clinical records and MRI of the brain and internal auditory canal of 11 children with DFP were retrospectively reviewed. Read More

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October 2018

Möbius syndrome: clinico-radiologic correlation.

Graefes Arch Clin Exp Ophthalmol 2018 Nov 1;256(11):2219-2223. Epub 2018 Aug 1.

Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 173-82 Gumiro, Bundang-gu, Seongnam, Gyeonggi-do, 13620, South Korea.

Purpose: Möbius syndrome is characterized by abducens and facial nerve palsy. However, the presence/absence of corresponding cranial nerves on MRI was not fully evaluated. The purpose of this study was to investigate the mechanism of Möbius syndrome by associating the presence of abducens and facial nerves on MR imagings with clinical features. Read More

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November 2018
1 Read

Bilateral Extensive Ossification of the Posterior Petroclinoid Ligament: An Anatomical Case Report and Literature Review.

J Neurol Surg A Cent Eur Neurosurg 2018 Jul 30. Epub 2018 Jul 30.

Department of Normal and Clinical Anatomy, Interfaculty Chair of Anatomy and Histology, Medical University of Lodz, Poland.

Background:  The posterior petroclinoid dural fold (commonly referred to as a ligament) forms the roof of the trigeminal porus and the roof of the petroclival venous confluence. It lies in close proximity to the oculomotor nerve that crosses it. Due to the low availability of research material, only a few cadaveric studies have been conducted on the microsurgical anatomy of the petroclinoid ligament in cases of its ossification. Read More

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July 2018
1 Read

Vascular Endothelial Growth Factor (VEGF) Prevents the Downregulation of the Cholinergic Phenotype in Axotomized Motoneurons of the Adult Rat.

Front Mol Neurosci 2018 12;11:241. Epub 2018 Jul 12.

Departamento de Fisiología, Facultad de Biología, Universidad de Sevilla, Seville, Spain.

Vascular endothelial growth factor (VEGF) was initially characterized by its activity on the vascular system. However, there is growing evidence indicating that VEGF also acts as a neuroprotective factor, and that its administration to neurons suffering from trauma or disease is able to rescue them from cell death. We questioned whether VEGF could also maintain damaged neurons in a neurotransmissive mode by evaluating the synthesis of their neurotransmitter, and whether its action would be direct or through its well-known angiogenic activity. Read More

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July 2018
11 Reads

Temporal Arteritis Presenting as an Isolated Bilateral Abducens Nerve Palsy: A Rare Case of a 65-year-old Male.

Cureus 2018 May 22;10(5):e2667. Epub 2018 May 22.

Department of Neurology, University Of Kentucky College of Medicine.

Giant cell arteritis (GCA) or temporal arteritis (TA) is a granulomatous inflammation of medium to large-sized arteries. It may have a diverse presentation. The most common presenting symptoms of GCA are fever, malaise, unilateral headache, jaw claudication, polymyalgia rheumatica (PMR) and ophthalmoplegia. Read More

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May 2018
6 Reads

An Incidental Finding of Ecchordosis Physaliphora in a Case of Abducens Nerve Palsy: Case Report.

Neuroophthalmology 2018 Aug 6;42(4):233-236. Epub 2017 Oct 6.

Department of Neurology, University of Illinois College of Medicine at Peoria, Peoria, Illinois, USA.

Ecchordosis physaliphora (EP) is a rare non-malignant mass that originates from remains of the notochord and is typically asymptomatic. A 42-year-old man presented with sudden onset of painless horizontal diplopia and his neurological exam showed sixth cranial nerve palsy. Magnetic resonance imaging (MRI) identified a non-enhanced retroclival mass (EP) with increased signal intensity on T2 and decreased signal intensity on T1-weighted sequences. Read More

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August 2018
4 Reads