35,000 results match your criteria Abdominal Pain in Elderly Persons


Solitary adrenal metastasis from advanced gastric cancer invading duodenal bulb with situs inversus totalis: A case report.

Medicine (Baltimore) 2019 Apr;98(15):e15244

Department of the General Surgery.

Rationale: Situs invsersus totalis (SIT) is a rare anomaly featured by complete inversion of abdominal and thoracic organs. Adrenal metastasis is often encountered as part of advanced systemic dissemination, which is usually unresectable. Few published cases reported the adrenal metastasis from gastric cancer with SIT and the treatment of gastrectomy combined with adrenalectomy, especially with intraoperative radiotherapy (IORT). Read More

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http://dx.doi.org/10.1097/MD.0000000000015244DOI Listing
April 2019
1 Read

Effectiveness, safety, and economic evaluation of topical application of a herbal ointment, Jaungo, for radiation dermatitis after breast conserving surgery in patients with breast cancer (GREEN study): Study protocol for a randomized controlled trial.

Medicine (Baltimore) 2019 Apr;98(15):e15174

Associate Professor, Department of Korean Obstetrics and Gynecology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, Republic of Korea.

Introduction: This is a prospective, open-label, parallel-group, randomized controlled trial that evaluates the effectiveness and safety of adjuvant application of Jaungo (JUG) for radiation-induced dermatitis (RD) in breast cancer patients undergoing radiation therapy, in comparison with general supportive care (GSC).

Methods/design: Eighty female patients, who have been diagnosed with unilateral breast cancer, will be allocated to either the JUG or GSC group with an allocation ratio of 1:1 after breast conservation surgery, in the Kyung Hee University Korean Medicine Hospital, Seoul, Republic of Korea. Both the groups will be subjected to GSC, but only the JUG group participants will apply adjuvant JUG ointment on the irradiated skin for 6 weeks, twice a day. Read More

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http://dx.doi.org/10.1097/MD.0000000000015174DOI Listing
April 2019
3 Reads

Traditional Chinese medicine for management of recurrent and refractory Crohn disease: A case report.

Medicine (Baltimore) 2019 Apr;98(15):e15148

Department of Thyroid.

Introduction: Crohn disease (CD) is a chronic relapsing systemic inflammatory disease afflicting the gastrointestinal system with a high morbidity. There has been increasing clinical interest in traditional Chinese medicine (TCM) treatment for CD. This report aims to present patient outcome of therapeutic management using TCM in combination with pharmacologic therapy. Read More

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http://dx.doi.org/10.1097/MD.0000000000015148DOI Listing
April 2019
1 Read

Acute pancreatitis with abdominal bloating and distension, normal lipase and amylase: A case report.

Medicine (Baltimore) 2019 Apr;98(15):e15138

Departments of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, PR China and Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, PR China.

Rationale: Acute pancreatitis is an inflammatory disorder of the pancreas, and its correct diagnosis is an area of interest for clinicians. In accordance with the revised Atlanta classification, acute pancreatitis can be diagnosed if at least 2 of the following 3 criteria are fulfilled: abdominal pain; serum lipase (or amylase) activity at least 3 times the upper limit of normal; or characteristic findings of acute pancreatitis on contrast-enhanced computed tomography (CT) or, less often, magnetic resonance imaging or transabdominal ultrasonography. Diagnostic imaging is essential in patients with no or slight enzyme elevation. Read More

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http://dx.doi.org/10.1097/MD.0000000000015138DOI Listing
April 2019
1 Read

Postoperative analgesia after total abdominal hysterectomy: Is the transversus abdominis plane block effective?

Niger J Clin Pract 2019 Apr;22(4):478-484

Department of Anesthesiology and Reanimation, Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital, Demetevler, Ankara, Turkey.

Background: Analgesic protocol is needed following gynecologic surgery to ensure early mobilization, decrease the duration in the post-anesthetic care unit and hospitalization, and provide patient comfort. Transversus abdominis plane (TAP) blocks are used in the treatment of acute postoperative pain after lower abdominal surgery. TAP block may be a better choice of postoperative pain control. Read More

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http://dx.doi.org/10.4103/njcp.njcp_61_15DOI Listing
April 2019
1 Read

A retrospective clinical and microbial analysis of 32 patients with bilomas.

BMC Gastroenterol 2019 Apr 4;19(1):50. Epub 2019 Apr 4.

Klinikum rechts der Isar, Technische Universität München, Innere Medizin II, Ismaningerstrasse 22, 81675, Munich, Germany.

Background: Bilomas are defined collections of bile fluids mainly caused by iatrogenic injuries of the bile duct system. Owing to the infrequency of this disease, studies addressing bilomas are rare.

Methods: By using an endoscopic database, this retrospective study identified 32 patients with bilomas treated between 2004 to 2015, in order to analyse aetiology, clinical presentation, spectrum of pathogens, and resolution rate of bilomas. Read More

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http://dx.doi.org/10.1186/s12876-019-0968-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450004PMC
April 2019
1 Read

Ulcerative colitis with mucosal lesions in duodenum: Two case reports.

Medicine (Baltimore) 2019 Apr;98(14):e15035

Department of General Surgery, Tianjin Union Medical Center, Tianjin, China.

Rationale: Ulcerative colitis (UC) is a chronic, nonspecific, inflammatory disease of the colon. Colorectal is the main target organ of UC, while other digestive tract involvement is rare. This report describes 2 rare cases of duodenal mucosa lesions in patients with UC after total colectomy. Read More

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http://dx.doi.org/10.1097/MD.0000000000015035DOI Listing
April 2019
3 Reads

Influenza A with hemorrhagic shock and encephalopathy syndrome in an adult: A case report.

Medicine (Baltimore) 2019 Apr;98(14):e15012

Department of Emergency and Acute Intensive Care Medicine, Kurume University School of Medicine, Fukuoka, Japan.

Introduction: Hemorrhagic shock and encephalopathy syndrome (HSES) is a type of acute encephalopathy mainly seen in infants. It is a syndrome encompassing an onset of high fever, disturbance of consciousness, convulsion, and shock that rapidly progresses to watery diarrhea and liver and renal dysfunctions. It is extremely rare in adults, and the number of reports is limited worldwide. Read More

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http://dx.doi.org/10.1097/MD.0000000000015012DOI Listing
April 2019
8 Reads

Clostridium difficile-associated diarrhea following the therapy with antibiotic and proton pump inhibitors in a 77-year-old man with several comorbidities: A case report.

Medicine (Baltimore) 2019 Mar;98(13):e15004

Department of Pharmacy.

Rationale: Clostridium difficile-associated diarrhea (CDAD) remains a persistent challenge, with substantially increased incidence and severity. The rising burden of CDAD requires urgent identification of preventable risk factors.

Patients Concerns: A 77-year-old man with the symptoms of abdominal pain and watery diarrhea was readmitted to the hospital, who received cephalosporins and proton pump inhibitors (PPIs) during the initial hospitalization for 12 days until discharge. Read More

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http://dx.doi.org/10.1097/MD.0000000000015004DOI Listing
March 2019
1 Read

Micrococcus aloeverae - A Rare Cause of Peritoneal Dialysis-Related Peritonitis Confirmed by 16S rRNA Gene Sequencing.

J Nippon Med Sch 2019 ;86(1):55-57

Department of Internal Medicine, Chonnam National University Medical School.

The number of patients receiving peritoneal dialysis has increased worldwide. Herein, we report the first case to our knowledge of continuous ambulatory peritoneal dialysis (CAPD) peritonitis caused by Micrococcus aloeverae, which was initially reported to be caused by Micrococcus luteus in the dialysate culture report but later identified by 16S ribosomal ribonucleic acid (rRNA) gene sequencing as M. aloeverae. Read More

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http://dx.doi.org/10.1272/jnms.JNMS.2019_86-10DOI Listing

Small bowel adenocarcinoma as a complication of celiac disease: clinical and diagnostic features.

BMC Gastroenterol 2019 Mar 27;19(1):45. Epub 2019 Mar 27.

Department of Medical Sciences, University of Ferrara, St. Anna Hospital, Via Aldo Moro, 8, 44124, Ferrara, Cona, Italy.

Background: Small bowel adenocarcinoma (SBA) is a rare neoplasm, which can occur in a sporadic form or can be associated with a number of predisposing conditions such as hereditary syndromes and immune-mediated intestinal disorders, e.g. celiac disease (CD). Read More

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http://dx.doi.org/10.1186/s12876-019-0964-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437995PMC
March 2019
1 Read

Use of Unenhanced Abdominal Computed Tomography for Assessment of Acute Non-Traumatic Abdominal Pain in the Emergency Department.

Isr Med Assoc J 2019 Mar;21(3):208-212

Department of Radiology, Hadassah-Hebrew University Medical Center, Mount Scopus Campus, Jerusalem, Israel.

Background: Acute non-traumatic abdominal pain is typically evaluated by abdomino-pelvic computed tomography (CT) with oral and venous contrast. The accuracy of unenhanced CT for diagnosis in this setting has not been widely studied.

Objectives: To assess the accuracy of unenhanced CT in establishing the etiology of acute non-traumatic abdominal pain. Read More

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March 2019
1 Read

The origin of p40-negative and CDX2-positive primary squamous cell carcinoma of the stomach: case report.

World J Surg Oncol 2019 Mar 19;17(1):53. Epub 2019 Mar 19.

Department of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan.

Background: Primary gastric squamous cell carcinoma (SCC) is a very rare disease. The origin of this tumor remains unclear, although there are some hypotheses. A 60-year-old man consulted a previous physician complaining of upper abdominal pain. Read More

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http://dx.doi.org/10.1186/s12957-019-1594-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425685PMC
March 2019
2 Reads

Validation and application of a module of the MD Anderson Symptom Inventory for measuring perioperative symptom burden in patients with gynecologic cancer (the MDASI-PeriOp-GYN).

Gynecol Oncol 2019 03;152(3):492-500

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.

Objective: Using patient-reported outcomes (PROs) in perioperative care is increasingly common. We report the development, validation, and application of an MD Anderson Symptom Inventory version for use in patients undergoing surgery for gynecologic cancer or benign conditions (MDASI-PeriOp-GYN).

Methods: Our process included: (1) generating PeriOp-GYN-specific candidate items from qualitative interviews with patients, followed by input from an expert panel; (2) dropping items that lacked independent clinical relevance; (3) validating psychometric properties (reliability, validity) of the resulting MDASI-PeriOp-GYN; and (4) conducting cognitive debriefing interviews with patients to confirm ease of comprehension, relevance, and acceptability. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00908258183136
Publisher Site
http://dx.doi.org/10.1016/j.ygyno.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422045PMC
March 2019
5 Reads

[Small bowel perforation caused by intestinal dissemination of pulmonary tuberculosis due to biological therapy].

Magy Seb 2019 Mar;72(1):13-19

Általános Sebészeti Osztály, Szent Pantaleon Kórház - Rendelőintézet Dunaújváros 2400 Dunaújváros, Korányi Sándor u. 4-6.

Case review: The authors present a case of a 78-year-old female patient who previously, as a teenager, had been treated for pulmonary tuberculosis. The biological therapy for subsequent inflammatory bowel disease in 2015 caused a flare up of the respiratory symptoms after 60 years of being asymptomatic, and the patient also developed acute abdomen. She required emergency laparotomy and small intestine segment resection was performed due to perforated ileum. Read More

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http://dx.doi.org/10.1556/1046.72.2019.1.3DOI Listing
March 2019
1 Read

Computed tomography scan imaging in diagnosing acute uncomplicated pancreatitis: Usefulness cost.

World J Gastroenterol 2019 Mar;25(9):1080-1087

Department of Gastroenterology, Advocate Christ Medical Center, Oak Lawn, IL 60453, United States.

Background: Literature has suggested that imaging is over-utilized in the diagnosis of pancreatitis. If the diagnosis of acute pancreatitis (AP) is established with abdominal pain and increased serum amylase or lipase activity without systemic signs of severe disease, computed tomography (CT) imaging may not be necessary. We hypothesize that among patients with uncomplicated acute pancreatitis (AUP), there is a significant number of unwarranted CT imaging studies. Read More

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http://dx.doi.org/10.3748/wjg.v25.i9.1080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406186PMC
March 2019
2 Reads

Significance of radiology in the diagnosis and management of ruptured left gastric artery aneurysm associated with acute pancreatitis: Case report.

Medicine (Baltimore) 2019 Mar;98(10):e14824

Department of Radiology, The First Affiliated Hospital of Dali University, Dali, Yunnan, People's Republic of China.

Rationale: Left gastric artery aneurysms are very rare which progresses into hemorrhagic shock and diagnosis is very challenging particularly in patients with acute pancreatitis and cholecystitis whose vitals become unstable suddenly.

Patient Concerns: A 72-year-old female has presented with severe progressing abdominal pain was treated with total parenteral nutrition for acute pancreatitis based on preliminary work up, but suddenly became unstable with dropping vitals over the ensuing 48 hours. Physical examination has a positive Murphy sign and appeared lethargic. Read More

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http://dx.doi.org/10.1097/MD.0000000000014824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417524PMC
March 2019
6 Reads

Concomitant occurrence of primary renal non-Hodgkin lymphoma and a colon cancer: A rare case report.

Medicine (Baltimore) 2019 Mar;98(10):e14802

Department of Pathology.

Rationale: Primary renal lymphoma (PRL) is a rare malignancy due to the absence of lymphatic tissues in the kidney, and patients with PRL have been reported to have a poor prognosis due to its rapid invasiveness and limited treatment strategies. Colon cancer is the third most common cancer, and has a high mortality rate. Both malignant diseases predominantly affected elderly men; however, a case with concomitant occurrence of the 2 cancers is extremely rare. Read More

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http://dx.doi.org/10.1097/MD.0000000000014802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417636PMC
March 2019
1 Read

Primary alveolar rhabdomyosarcoma of retrorectal-presacral space in an adult patient: A case report of an uncommon tumor with rare presentation.

Medicine (Baltimore) 2019 Mar;98(10):e13416

Department of Radiology.

Rationale: Rhabdomyosarcoma (RMS) has known as a highly malignant soft tissue sarcoma, representing 5% to 10% of all solid tumors in childhood. Alveolar rhabdomyosarcoma (ARMS) of the retrorectal-presacral space is an extremely rare lesion for adult, no study has been reported in the English literature.

Patient Concerns: A 51-year-old male presented with abdominal pain for 1 month, significantly worse when having a bowel movement. Read More

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http://dx.doi.org/10.1097/MD.0000000000013416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417633PMC
March 2019
1 Read

[Embolization of insufficient pelvic veins for pelvic congestion syndrome. Analysis of 17 cases].

Rev Med Chil 2019 ;147(1):41-46

Departamento de Cirugía Vascular y Endovascular, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Background: Pelvic venous insufficiency may cause pelvic congestion syndrome that is characterized by chronic pelvic pain exacerbated by prolonged standing, sexual activity or menstrual cycle. It may be treated by embolizing the dysfunctional pelvic venous drainage and sometimes resecting vulvar, perineal and thigh varices.

Aim: To assess the results of embolization of insufficient pelvic or ovarian veins on pelvic congestion syndrome. Read More

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http://dx.doi.org/10.4067/S0034-98872019000100041DOI Listing
March 2019
10 Reads

Eosinophilic oesophagitis (in nickel-allergic patient) regressed after nickel oral desensitization: A case report.

Int J Immunopathol Pharmacol 2019 Jan-Dec;33:2058738419827771

3 Endoscopic Digestive Surgery, IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy.

The eosinophilic oesophagitis (EoE) is a chronic immune/antigen disorder of the oesophagus clinically characterized by dysphagia and pathologically by mucosa eosinophilic infiltration. Th2-type allergic reactions are considered having important roles in the aetiopathogenesis of EoE. Avoidance of food allergens, administration of steroidal anti-inflammatory medications and dilation of the oesophagus are the most important treatments. Read More

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http://dx.doi.org/10.1177/2058738419827771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407324PMC
March 2019
8 Reads

Clinicopathological characteristics of renal solitary fibrous tumor: A single institution experience.

Medicine (Baltimore) 2019 Feb;98(8):e14618

Department of Urology, The First Affiliated Hospital of GuangXi Medical University,NanNing.

To analyze the clinical characteristics, treatment modalities and outcomes of adult renal solitary fibrous tumors (SFT) treated at a single institution. Demographic, diagnostic, surgical, and pathological findings of patients who had undergone radical nephrectomy (RN) due to renal SFT were collected from the database of a single institution and were retrospectively reviewed. Ten patients (6 men and 4 women) were diagnosed with renal SFT in our institution between January 1, 2000 and December 31, 2016. Read More

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http://dx.doi.org/10.1097/MD.0000000000014618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407932PMC
February 2019
2 Reads

Sonographic diagnosis of perforation of the gastric antrum caused by a foreign body: A case report.

Medicine (Baltimore) 2019 Feb;98(8):e14586

Department of Ultrasound, Lanxi People's Hospital, Jinhua, Zhejiang, China.

Rationale: Ingestion of foreign bodies often occurs in clinical environments, especially in toddlers and aged patients. Although plain radiography and CT are widely used for the assessment of foreign bodies, sonography has an advantage in the diagnosis of some radiolucent foreign bodies, such as wood and bamboo materials.

Patient Concerns: An 80-year-old woman presented with a 4-day history of right upper quadrant abdominal persistent distended pain without radiation. Read More

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http://dx.doi.org/10.1097/MD.0000000000014586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408005PMC
February 2019

Apatinib treatment of advanced hepatocellular carcinoma with portal vein and inferior vena cava tumor thrombus: A case report.

Medicine (Baltimore) 2019 Feb;98(8):e14582

Department of Interventional Radiology, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, China.

Rationale: Hepatocellular carcinoma (HCC) is a highly invasive cancer associated with vascular invasion. The survival of advanced HCC is very poor. In this case study, we describe the efficacy and safety of apatinib in patient with advanced HCC as the first-line therapy. Read More

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http://dx.doi.org/10.1097/MD.0000000000014582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408098PMC
February 2019
3 Reads

Observation of the curative effect of device-guided rehabilitation on respiratory function in stable patients with chronic obstructive pulmonary disease.

Medicine (Baltimore) 2019 Feb;98(8):e14034

Respiratory Department, Jiaxing Second Hospital, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang Province, China.

Background: Chronic obstructive pulmonary disease (COPD) is a serious lung disease for individuals in middle age and especially in old people. The study was aimed to observe the curative effect of device-guided rehabilitation on respiratory functions in stable COPD patients.

Methods: Sixty-seven stable COPD patients were enrolled and assigned to the experiment group (n = 36) and the control group (n = 31). Read More

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http://dx.doi.org/10.1097/MD.0000000000014034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408035PMC
February 2019
1 Read

Aortic Dissection Associated with Autosomal Dominant Polycystic Kidney Disease

Heart Surg Forum 2019 02 6;22(1):E032-E034. Epub 2019 Feb 6.

Department of Cardiovascular Surgery, St. Mary's Hospital, Kurume, Japan.

A 78-year-old man who had been diagnosed with autosomal dominant polycystic kidney disease (ADPKD) and hypertension presented with chest pain. His family history was positive for ADPKD. Chest computed tomography (CT) revealed a type A aortic dissection with thrombotic occlusion of a false lumen and an ulcer-like projection in the ascending aorta, an aneurysm of the ascending aorta, and pericardial effusion. Read More

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http://dx.doi.org/10.1532/hsf.2027DOI Listing
February 2019
2 Reads

Pros and cons of gastric bypass surgery in individuals with obesity and type 2 diabetes: nationwide, matched, observational cohort study.

BMJ Open 2019 Jan 15;9(1):e023882. Epub 2019 Jan 15.

Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden.

Objectives: Long-term effects of gastric bypass (GBP) surgery have been presented in observational and randomised studies, but there are only limited data for persons with obesity and type 2 diabetes mellitus (T2DM) regarding postoperative complications.

Design: This is a nationwide observational study based on two quality registers in Sweden (National Diabetes Register, NDR and Scandinavian Obesity Surgery Register, SOReg) and other national databases.

Setting: After merging the data, we matched individuals with T2DM who had undergone GBP with those not surgically treated for obesity on propensity score, based on sex, age, body mass index (BMI) and calendar time. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340417PMC
January 2019
7 Reads

Association between digestive symptoms and sleep disturbance: a cross-sectional community-based study.

BMC Gastroenterol 2019 Feb 19;19(1):34. Epub 2019 Feb 19.

Future Medicine Division, Korea Institute of Oriental Medicine, Daejeon, 1672, Republic of Korea.

Background: This study was conducted to analyze the association between digestive symptoms and sleep disturbance, and to determine if any digestive symptoms are related to sleep disturbance.

Methods: This was a cross-sectional study of 5792 subjects surveyed in a community-based cohort. Subjects provided information regarding the quality of sleep as assessed by the Pittsburgh Sleep Quality Index (PSQI), as well as digestive symptoms as assessed by the Gastrointestinal Symptom Rating Scale (GSRS). Read More

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http://dx.doi.org/10.1186/s12876-019-0945-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381712PMC
February 2019
6 Reads

Mesenteric diverticuli as a reason of acute abdomen.

Rozhl Chir Winter 2019;98(1):27-30

Introduction: Diverticula of the small bowel are quite rare findings, frequently confirme only by necropsy. The authors describe the signs and symptoms resulting from complications of small bowel diverticula as well as the diagnostic options and treatment modalities. The paper also presents the results of treatment in the Department of Surgery at University Hospital in Pilsen. Read More

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A unique presentation of superinfected pseudomyxoma peritonei secondary to a low-grade appendiceal mucinous neoplasm.

World J Surg Oncol 2019 Feb 18;17(1):34. Epub 2019 Feb 18.

Department of Surgical Oncology, Mount Sinai St. Luke's West Hospital, 425 W. 59th St., 7th Floor, New York, NY, 10019, USA.

Background: Pseudomyxoma peritonei (PMP) is an uncommon condition characterized by diffuse mucinous material in the abdomen and pelvis, generally arising from a perforated epithelial neoplasm. Typically, the disease presents as suspected acute appendicitis, ovarian mass, abdominal distension, or ventral hernia. Our case represents a very rare presentation of superinfected PMP. Read More

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http://dx.doi.org/10.1186/s12957-019-1578-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379993PMC
February 2019
2 Reads

Analysis of intrahepatic sarcomatoid cholangiocarcinoma: Experience from 11 cases within 17 years.

World J Gastroenterol 2019 Feb;25(5):608-621

Department of Internal Medicine, Dong-A University College of Medicine, Busan 49201, South Korea.

Background: Intrahepatic sarcomatoid chonalgiocarcinoma (s-CCC) is an extremely rare disease, accounting for less than 1% of hepatobiliary system malignancies, and its pathophysiology is not well known. On the hypothesis that its clinical, serologic, or radiologic diagnosis are not fully understood and its prognosis is poor, we investigated the distinguishing features of s-CCC compared with those of intrahepatic bile duct adenocarcinoma [cholangiocellular carcinoma (CCC)] in patients from a single center.

Aim: To analyze the clinical, serologic, imaging, and histopathologic characteristics of intrahepatic s-CCC patients diagnosed in a single center. Read More

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http://dx.doi.org/10.3748/wjg.v25.i5.608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371010PMC
February 2019
2 Reads

[Surgical Repair of Stanford Type A Acute Aortic Dissection Associated with Anomalous Retroaortic Left Brachiocephalic Vein;Report of a Case].

Kyobu Geka 2019 Feb;72(2):153-155

Department of Cardiovascular Surgery, Yokohama Medical Center, Yokohama, Japan.

Anomalous retroaortic left brachiocephalic vein( ARLBV) is a rare vascular abnormaly, usually asossiated with congenital heart diseases. We present a very rare case of Stanford type A acute aortic dissection associated with ARLBV. A 70-year-old man was referred to our hospital complaining of worsening back pain and chest pain. Read More

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February 2019
1 Read

Retrospective analysis of 30-day unplanned readmission after major abdominal surgery with reversal by sugammadex or neostigmine.

Br J Anaesth 2019 Mar 2;122(3):370-378. Epub 2019 Jan 2.

Department of Biostatistics, Korea University College of Medicine, Seoul, Republic of Korea.

Background: Sugammadex is associated with fewer postoperative complications, but its impact on 30-day unplanned readmission is unclear.

Methods: This was a single-centre retrospective observational study of patients after major abdominal surgery between 2010 and 2017, where rocuronium was the only neuromuscular blocker used. The primary endpoint was the difference in incidence of 30-day unplanned readmission between reversal with sugammadex or neostigmine. Read More

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http://dx.doi.org/10.1016/j.bja.2018.11.028DOI Listing
March 2019
7 Reads
4.853 Impact Factor

Monomorphic epitheliotropic intestinal T-cell lymphoma may mimic intestinal inflammatory disorders.

Int J Immunopathol Pharmacol 2019 Jan-Dec;33:2058738419829387

3 Department of Pharmacology, Wuhan University, Wuhan, P.R. China.

There is a significant overlap between intestinal lymphoproliferative disorders (LPDs) and inflammatory conditions of the intestine, including inflammatory bowel disease (IBD), in clinical, endoscopic, or histologic appearance, leading to diagnostic challenges. We report two cases of monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) that were initially considered to be ulcerative colitis (UC) and lymphocytic colitis, respectively. Both patients presented with diarrhea and abdominal pain. Read More

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http://dx.doi.org/10.1177/2058738419829387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376542PMC
March 2019
1 Read

Association of Thoracic Epidural Pain Management with Urinary Retention after Complex Abdominal Wall Reconstruction.

Am Surg 2018 Nov;84(11):1808-1813

The association of thoracic epidural analgesia and urinary retention after complex abdominal wall reconstruction (CAWR) is unknown. The purpose of this study was to investigate the association between the presence of a thoracic epidural, timing of Foley catheter removal, and the rates of urinary retention and catheter-associated urinary tract infections (CAUTIs) in patients undergoing CAWR. All patients undergoing CAWR, who had an epidural catheter for postoperative pain management at our institution from September 2015 through April 2016, were prospectively followed. Read More

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November 2018
2 Reads

Surgical outcomes and quality of life between laparoscopic and open approach for hepatic hemangioma: A propensity score matching analysis.

Medicine (Baltimore) 2019 Feb;98(6):e14485

Department of Liver Surgery, Center of Liver Transplantation, West China Hospital.

The main objective of the study was to compare the surgical outcomes and quality of life (QOL) of patients with hepatic hemangioma either by laparoscopic or open surgery using a propensity score analysis.We retrospectively reviewed patients with hepatic hemangioma undergoing laparoscopic liver surgery (LLS) or open liver surgery (OLS) between January 2016 and December 2017. Intraoperative and postoperative characteristics, and quality of life, according to Short Form-36 Healthy Survey (SF-36) questionnaire, were compared between groups. Read More

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http://dx.doi.org/10.1097/MD.0000000000014485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380717PMC
February 2019
10 Reads

An inadvertent subarachnoid injection reversed by cerebrospinal fluid lavage for the treatment of chronic low back pain: A case report.

Medicine (Baltimore) 2019 Feb;98(6):e14406

Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.

Rationale: We present a case of high spinal anesthesia after inadvertent injection of local anesthetics and corticosteroids into the subarachnoid space during attempted epidural injection. Cerebrospinal fluid (CSF) lavage is a suitable method for treatment.

Patient Concerns: A 45-year-old woman presented with posterior thigh, leg, and ankle pain for >6 months and was treated with epidural injection. Read More

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http://dx.doi.org/10.1097/MD.0000000000014406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380745PMC
February 2019
2 Reads

Hybrid repair for a complex infection aortic pseudoaneurysm with continued antibiotic therapy: A case report and literature review.

Medicine (Baltimore) 2019 Feb;98(6):e14330

Department of Vascular Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Introduction: Treatment of infection aortic pseudoaneurysm (PSA) is a great challenge to surgeons for 3 reasons: high mortality for rupture or threatened rupture; potential risk for infection of prosthetic material which probably bring a devastating result for patients; and long-term antibiotic therapy requirement. Endovascular repair is an alternative to open surgery for a less invasive, which is a trouble procedure for aortic PSA with complex aortic anatomy. The purpose of this article is to report the novel hybrid repair of an infection aortic PSA and antibiotics therapy. Read More

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http://dx.doi.org/10.1097/MD.0000000000014330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380711PMC
February 2019
2 Reads

Effectiveness of Parecoxib Sodium Combined with Transversus Abdominis Plane Block for Pain Management After Hepatectomy for Hepatocellular Carcinoma: A Prospective Controlled Study.

Med Sci Monit 2019 Feb 7;25:1053-1060. Epub 2019 Feb 7.

Department of General Surgery, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China (mainland).

BACKGROUND This study aimed to investigate the effectiveness of perioperative parecoxib sodium combined with transversus abdominis plane (TAP) block on postoperative pain management following hepatectomy in patients with hepatocellular carcinoma (HCC). MATERIAL AND METHODS One hundred patients with HCC who underwent hepatectomy were randomized into a study group (n=51) and a control group (n=49). The study group received 40 mg of parecoxib sodium 30 minutes before anesthetic induction, and 150 mg of 0. Read More

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http://dx.doi.org/10.12659/MSM.912843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375540PMC
February 2019
2 Reads

Lessons learned from an unusual condition of incidental synchronous multiple hernias of indirect inguinal hernia, femoral hernia, and incarcerated obturator hernia.

Niger J Clin Pract 2019 Feb;22(2):281-284

Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, China.

Hernias are one of the most common diseases. The frequency of multiple hernias is much higher than the frequency reported during herniorrhaphy. Multiple hernias may account for some of the so-called recurrences, in which the small hernia may be veiled by the bigger one and omitted. Read More

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http://dx.doi.org/10.4103/njcp.njcp_200_18DOI Listing
February 2019
2 Reads

Spontaneous Rectus Sheath Hematoma: An Uncommon Cause of Acute Abdominal Pain.

Am J Case Rep 2019 Feb 7;20:163-166. Epub 2019 Feb 7.

Department of Internal Medicine, United Health Services Hospitals, Wilson Medical Center, Johnson City, NY, USA.

BACKGROUND A clinical condition that is often misdiagnosed, rectus sheath hematoma (RSH) is usually seen in the context of blunt abdominal trauma and/or anticoagulation therapy, rarely occurring spontaneously. We present a case of spontaneous rectus sheath hematoma (SRSH) without obvious risk factors and review the literature regarding diagnosis modalities and management. The aim of this case presentation is to highlight this rare clinical condition and emphasize the role of the physical exam in determining the appropriate treatment approach. Read More

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http://dx.doi.org/10.12659/AJCR.913246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375283PMC
February 2019
2 Reads

Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria.

N Engl J Med 2019 02;380(6):549-558

From the Porphyria Centre Sweden, Karolinska Institutet, Karolinska University Hospital, Stockholm (E.S., P.H., D.V.); Icahn School of Medicine at Mount Sinai, New York (M.B., R.D.); King's College Hospital, London (P.S., D.R.); University of California, San Francisco, San Francisco (D.M.B.); University of Utah, Salt Lake City (C. Parker, J.P.); Wake Forest University, Winston-Salem, NC (H.L.B.); Alnylam Pharmaceuticals, Cambridge, MA (C. Penz, A.C.-D., Q.H., W.Q., K.F., J.B.K., P.G., A.V., A.R.S.); and the University of Texas Medical Branch at Galveston, Galveston (K.E.A.).

Background: Induction of delta aminolevulinic acid synthase 1 ( ALAS1) gene expression and accumulation of neurotoxic intermediates result in neurovisceral attacks and disease manifestations in patients with acute intermittent porphyria, a rare inherited disease of heme biosynthesis. Givosiran is an investigational RNA interference therapeutic agent that inhibits hepatic ALAS1 synthesis.

Methods: We conducted a phase 1 trial of givosiran in patients with acute intermittent porphyria. Read More

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http://dx.doi.org/10.1056/NEJMoa1807838DOI Listing
February 2019
5 Reads

Intestinal necrosis cannot be neglected in a patient with hepatic portal vein gas combined with appendicitis: a rare case report and literature review.

BMC Surg 2019 Feb 4;19(1):17. Epub 2019 Feb 4.

Department of Hepatobiliary Surgery, the Second Affiliated Hospital, Nanchang University, No. 1, mingde road, Nanchang, Jiang xi, China.

Background: Hepatic portal vein gas (HPVG) is a rare acute abdomen, which is not an independent disease. Meanwhile, HPVG combined with appendicitis has been rarely reported. We found only a similar report by looking for literature, but no intestinal necrosis occurred. Read More

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http://dx.doi.org/10.1186/s12893-019-0478-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360744PMC
February 2019
3 Reads

A Rare Case of Spontaneous Tumor Lysis Syndrome in Idiopathic Primary Myelofibrosis.

Am J Case Rep 2019 Feb 3;20:146-150. Epub 2019 Feb 3.

Department of Hemato-Oncology, Chosun University Hospital, Gwangju, South Korea.

BACKGROUND Tumor lysis syndrome (TLS) is an oncologic emergency resulting from the massive destruction of tumor cells after cytotoxic chemotherapy for chemosensitive malignancies with a high tumor burden. Its clinical manifestations include severe electrolyte disturbances, metabolic acidosis, acute renal failure secondary to urate deposition in the kidney, heart, and skeletal muscle, and nervous system dysfunction. We report an extremely rare case of spontaneous TLS (STLS) in idiopathic primary myelofibrosis (PMF). Read More

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http://dx.doi.org/10.12659/AJCR.912682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369657PMC
February 2019
8 Reads

Tolerability and activity of ublituximab, umbralisib, and ibrutinib in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: a phase 1 dose escalation and expansion trial.

Lancet Haematol 2019 Feb;6(2):e100-e109

The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: Therapeutic approaches for B-cell malignancies continue to evolve, especially with regard to combination approaches. We assessed the safety and efficacy of the triplet ublituximab, umbralisib, and ibrutinib in patients with advanced B-cell malignancies.

Methods: We did an open-label, phase 1 study with dose-escalation and dose-expansion phases, at five centres in the USA. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23523026183021
Publisher Site
http://dx.doi.org/10.1016/S2352-3026(18)30216-3DOI Listing
February 2019
16 Reads

Long-term survival of an elderly female with metastatic colon cancer after treated with capecitabine monotherapy: A case report.

Medicine (Baltimore) 2019 Feb;98(5):e14326

Department of Medical Oncology, First Affiliated Hospital, School of Medicine, Zhejiang University, 79# Qingchun Road.

Rationale: Colorectal cancer (CRC) is one of the most common cancers all over the world, and approximately 70% of the newly diagnosed patients are over 65 years old. Due to the aging of society, there will be more and more elderly patients of CRC in the future. Treatment of CRC in elderly patients is much more challenging thanks to multiple factors including disabling comorbidities as well as declines in organs function, especially in advanced or metastatic settings. Read More

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http://dx.doi.org/10.1097/MD.0000000000014326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380827PMC
February 2019
9 Reads

Effectiveness of mebeverine in patients with post-cholecystectomy gastrointestinal spasm: results of prospective observational program "odyssey".

Ter Arkh 2018 Aug;90(8):40-47

Abbott Laboratories, Moscow, Russia.

Aim: To assess the effectiveness of mebeverine 200 mg BID in patients with post-cholecystectomy gastrointestinal spasm not requiring surgical treatment.

Materials And Methods: 218 patients were included in 16 clinical centers in 14 cities in Russia. All patients had post-cholecystectomy gastrointestinal spasms, not requiring surgical treatment and received mebeverine (Duspatalin®) 200 mg BID. Read More

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http://dx.doi.org/10.26442/terarkh201890840-47DOI Listing
August 2018
1 Read

The prevalence of Helicobacter pylori infection among urban population.

Ter Arkh 2018 Apr;90(4):17-20

I.P. Pavlov Ryazan State Medical.

Aim: Determination of the prevalence of Helicobacter pylori infection (H. pylori) among the urban population.

Materials And Methods: 655 people (638 adults and 17 children) were examined using the immunoassay method of quantitative detection of IgG class antibodies. Read More

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http://dx.doi.org/10.26442/terarkh201890417-20DOI Listing
April 2018
1 Read

Peutz-Jeghers Syndrome.

N Engl J Med 2019 Jan;380(5):472

R.G. Kar Medical College and Hospital, Kolkata, India

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http://dx.doi.org/10.1056/NEJMicm1806623DOI Listing
January 2019
3 Reads