Search Our Scientific Publications & Authors

Int J Surg Case Rep 2018 Nov 22;54:51-54. Epub 2018 Nov 22.

Department of Surgery, Epworth Health, Melbourne Australia; Gastrointestinal Clinical Institute, Epworth HealthCare, Melbourne Australia.

Introduction: There is a known association between Clostridium Septicum, mycotic aneurysm and colon neoplasm.

Case Presentation: We report the case of a 90 year old female admitted with abdominal pain to the general surgery unit. Admission CT scan demonstrated a thick walled caecum and pericaecal inflammation suspicious for a perforated carcinoma. Read More

Int J Surg Case Rep 2018 Nov 22;54:47-50. Epub 2018 Nov 22.

Department of General Surgery, King Abdulla University Hospital, Faculty of Medicine, Jordan University of Science and Technology, P.O. Box (3030), Irbid, 22110, Jordan. Electronic address:

Introduction: Sacrococcygealteratoma is very rare in adults with only few cases reported in literature. It is a slow growing benign cystic tumor with 1-2% chance for malignant transformation and may attain a huge size causing pressure effect on pelvic and intra-abdominal organs. When grows caudally, it causes discomfort, skin excoriation and cosmetic disfigurement. Read More

Eur J Pharm Sci 2018 Dec 3. Epub 2018 Dec 3.

Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary. Electronic address:

A new renaissance started in the research and application of cyclodextrins a few years ago. 2-Hydroxypropyl-beta-cyclodextrin (HPBCD) is used in the formulation of drugs and recently orphan designation was granted for the treatment of Niemann-Pick disease, type C. HPBCD is considered to be safe, but the exact mechanism of action and side effects are not completely explained. Read More

Cochrane Database Syst Rev 2018 Dec 3;12:CD012624. Epub 2018 Dec 3.

Department of Surgery and Anaesthesia, Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, University of Nottingham, Uttoxeter New Road, Derby, UK, DE22 3DT.

Background: Postoperative pain is a common consequence of surgery and can have deleterious effects. It has been suggested that the administration of opioid analgesia before a painful stimulus may improve pain control. This can be done in two ways. Read More

PLoS One 2018 6;13(12):e0208647. Epub 2018 Dec 6.

Department of Entomology and Nematology, University of Florida, Gainesville, FL, United States of America.

The fall armyworm (FAW), Spodoptera frugiperda (J.E. Smith), is an important pest of maize in the Americas and has recently been introduced into Africa. Read More

PLoS One 2018 6;13(12):e0208435. Epub 2018 Dec 6.

Occupational and environmental medicine, Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Recurrent headache, abdominal and musculoskeletal pain are common in adolescents and it is therefore important to understand their impact on the transitional period from childhood to adulthood. However, studies of the prevalence over time and implications on educational outcomes are still limited, especially regarding multiple pain symptoms. The present study material consists of questionnaire surveys, completed in 2000 and 2008, including two study populations of 9th grade adolescents aged 15 living in West Sweden (n = 20 877). Read More

Folia Med Cracov 2018 ;58(3):103-114

Department of Experimental and Clinical Surgery, Jagiellonian University Medical College Kraków, Poland.

Inguinal hernia repairs are one of the most common procedures performed in general surgical departments. Approximately 20 million hernia repairs are performed annually all over the world. According to the EHS guidelines, the recommended treatment methods of the inguinal hernia are tension-free techniques: the Lichtenstein open hernia repair and the laparoscopic transabdominal preperitoneal (TAPP) and totally extraperitoneal (TEP) methods. Read More

Rom J Intern Med 2018 Dec;56(4):233-242

Laboratory of Allergology and Clinical Immunology, "Nicolae Testemitanu" State University of Medicine and Pharmacy, Chisinau, Republic of Moldova.

Pancreas divisum (PD) is the most common developmental anatomic variant of pancreatic duct. The attention towards the PD has grown significantly since there are reports that this condition may cause acute relapsing pancreatitis, chronic pancreatitis and chronic abdominal pain syndrome. Furthermore, over the years, there have been multiple reports of PD associated with different types of tumors. Read More

Rev Med Inst Mex Seguro Soc 2018 11 30;56(4):414-417. Epub 2018 Nov 30.

Instituto Mexicano del Seguro Social, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad de Investigación Médica en Enfermedades Nefrológicas. Ciudad de México, México

Background: Kidney transplantation presents a susceptible point, and is related to infections; tuberculosis is a common and endemic etiology in a country like Mexico, where the most frequent presentation is the respiratory condition, the extrapulmonary is extremely rare and it is derived from immunosuppression conditions.

Case Report: 33-year-old man with kidney disease of undetermined etiology, kidney transplant in 2003 (donor mother) with adequate evolution; presented with chronic graft nephropathy, with baseline creatinine of 1.8 mg / dL, immunosuppression with prednisone 10 mg every 24 hours, mycophenolate mofetil 500 mg every 8 hours and ciclosporin 100 mg every 12 hours; surgical intervention was performed due to acute abdomen, appendectomy and omentectomy with histopathological finding of tuberculosis, Dotbal, antiproliferative in suspension was started and decrease of calcineurin inhibitor. Read More

JBRA Assist Reprod 2018 Dec 6. Epub 2018 Dec 6.

Nursing Research Center, Golestan University of Medical Sciences, Gorgan, IR Iran.

Objectives: Primary dysmenorrhea is a painful uterine contraction caused by endometrial laceration. Drug therapies and complementary medicine have been used to treat dysmenorrhea. The aim of this study was to investigate and offer an updated perspective on the treatments for dysmenorrhea. Read More

Jpn J Clin Oncol 2018 Dec 6. Epub 2018 Dec 6.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Background: We investigated the practice patterns of surgery for advanced ovarian cancer (AOC) through relevant international surveys.

Methods: After searching for 878 studies on surgery for AOC till 2017, we extracted 18 questions with similar query and answer formats from eight studies. Among them, 5 and 13 were classified as comprehensive and procedure information. Read More

Surg Laparosc Endosc Percutan Tech 2018 Dec 4. Epub 2018 Dec 4.

Departments of General Surgery.

Background: Laparoscopic sleeve gastrectomy (LSG) has become more popular among other bariatric procedures. The histopathologic changes in the sleeve gastrectomy specimens have not been widely investigated among the Turkish population.

Objective: The purpose of this study was to delineate these histopathologic findings of the LSG specimens of morbidly obese patients from a single center. Read More

Ir Med J 2018 08 13;111(7):792. Epub 2018 Aug 13.

University Hospital Galway, Ireland

Introduction A 62-year-old lady presented to The Emergency Department (ED) with one-day history of dizziness, vomiting and feeling weak. ECG showed new onset Atrial Fibrillation. Four days ago, she was referred to the Cardiology team where she underwent PCI and was discharged on Apixaban and Plavix. Read More

Curr Aging Sci 2018 Dec 5. Epub 2018 Dec 5.

Acute Geriatrics Unit, Monza (MB). Italy.

Introduction: Doege-Potter syndrome (DPS) is a rare but life-threatening paraneoplastic syndrome, characterized by non-islet cell tumor-induced hypoglycemia (NICTH) secondary to a solitary fibrous tumor (SFT), which secretes an incompletely processed form of insulin-like growth factor 2 (IGF-2).

Results: A 96-year-old woman was admitted with head trauma due to an accidental fall. During her hospital stay she experienced frequent hypoglycemic episodes. Read More

Ir Med J 2018 06 7;111(6):774. Epub 2018 Jun 7.

Department of Gynaecology, the Adelaide and Meath National Children's Hospital, Dublin, Republic of Ireland

Caesarean scar ectopic pregnancy (CSEP) is one of the rarest forms of ectopic pregnancies. With rising caesarean delivery (CD) rates worldwide, there is an increase in the incidence of CSEP. Patients usually present with painless vaginal bleeding and often misdiagnosed as spontaneous miscarriage. Read More

J Dig Dis 2018 Dec 5. Epub 2018 Dec 5.

Division of Gastroenterology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Objective: Few studies have systematically assessed symptom-based diagnosis of functional gastrointestinal disorders (FGIDs) in China. This study aimed to evaluate the positive endoscopic and ultrasonographic findings in symptom-based FGID patients.

Methods: Adult patients with gastrointestinal symptoms but not red flag symptoms who were empirically diagnosed with FGIDs underwent upper and/or lower gastrointestinal endoscopy based on their symptoms. Read More

Eur Radiol 2018 Dec 5. Epub 2018 Dec 5.

Department of Radiology, Kanazawa University Graduate School of Medical Science, 13-1 Takaramachi, Kanazawa, 920-8641, Japan.

Objectives: To identify imaging features that assist in discriminating intraductal papillary neoplasms of the bile duct (IPNBs) from papillary cholangiocarcinomas (PCCs).

Methods: This study was approved by the institutional review board. Using the recently proposed histological diagnostic criteria for biliary papillary neoplasms, IPNBs and PCCs were selected from 537 biliary neoplasms consecutively resected in a 12. Read More

Int J Colorectal Dis 2018 Dec 5. Epub 2018 Dec 5.

Department of Surgery, University Hospital of Bonn, Bonn, Germany.

Purpose: Postoperative ileus (POI) is a common complication after abdominal surgery. Invasive stimulation of the cervical vagus nerve is known to reduce inflammatory response and ameliorated POI after surgery in a mouse model. However, the transcutaneous vagus nerve stimulation (tVNS) is a possible non-invasive approach. Read More

Abdom Radiol (NY) 2018 Dec 5. Epub 2018 Dec 5.

Division of Abdominal Imaging/Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02115, USA.

Objective: To evaluate clarity, completeness, and impact on surgical planning of MRI reporting of perianal fistulizing disease using a structured disease-specific template versus narrative reporting for planning of disease treatment by colorectal surgeons.

Materials And Methods: In this HIPAA-compliant, IRB-approved study with waiver of informed consent, a structured reporting template for perianal fistulizing disease MRIs was developed based on collaboration between colorectal surgeons and abdominal radiologists. The study population included 45 consecutive patients who underwent pelvic MRI for perianal fistulizing disease prior to implementation of structured reporting, and 60 consecutive patients who underwent pelvic MRI for perianal fistulizing disease after implementation of structured reporting. Read More

Eur J Nutr 2018 Dec 5. Epub 2018 Dec 5.

Major of Food Science and Nutrition, School of Human Ecology, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon, 14662, Republic of Korea.

Purpose: Although a high-carbohydrate diet typically shows low-fat intake, the prevalence of metabolic abnormalities in Asian countries has increased. We evaluated three types of a high-carbohydrate diet and its association with cardiometabolic risk factors in the Korean adult population.

Methods: A total of 14,438 adults (5813 men and 8625 women) who participated in the 2008-2012 Korea National Health and Nutrition Examination Surveys were selected. Read More

Res Rep Urol 2018 13;10:195-197. Epub 2018 Nov 13.

Department of Surgery, Apollo Hospitals, Guwahati, India.

Loss of tone of the anterolateral abdominal wall muscles due to denervation injury is quite common after open renal surgery by lumbotomy incision. Although rare, flank bulge following percutaneous nephrolithotomy (PCNL) after supracostal approach has been reported in literature. But pseudohernia after PCNL with subcostal access has not been reported yet. Read More

Respir Med Case Rep 2019 15;26:42-44. Epub 2018 Nov 15.

Great Western Hospital, Swindon, Marlborough Road, SN3 6BB, UK.

A 46 year old lady presented three weeks after an oesophagectomy for oesophageal carcinoma with increasing breathlessness and a large left-sided pleural effusion. Computed tomography (CT) scan of her thorax, abdomen and pelvis revealed a large left-sided and small right-sided pleural effusions, a pericardial effusion, ascites and intra-abdominal lymphadenopathy. The patient underwent both pericardial and pleural fluid drainage, however, unfortunately, deteriorated despite these interventions with increasing oxygen requirements requiring nasal high flow oxygen on the Intensive Care Unit. Read More

Respirol Case Rep 2019 Feb 28;7(2):e00391. Epub 2018 Nov 28.

Department of Medical Oncology Izumi City General Hospital Izumi Japan.

Porous diaphragm syndrome describes a defect in the diaphragm in which substances pass from the peritoneal cavity to the pleural space. Defects may be congenital or acquired. Acquired defects are caused by the thinning and eventual splitting of collagen fibres in the tendinous part of the diaphragm. Read More

Ann Med Surg (Lond) 2018 Dec 13;36:231-234. Epub 2018 Nov 13.

Department of Surgery, University Hospital Hairmyres, NHS Lanarkshire, East Kilbride, G75 8RG, Scotland, UK.

Introduction: Unexplained lactic acidosis (LA) in a critically ill patient often prompts investigations to rule out any reversible intra-abdominal cause. Equivocal results can lead to an emergency laparotomy (EL) with subsequent high morbidity and mortality rates. Our objective was to determine the clinical impact of urgent diagnostic laparoscopy (UDL) in such patients. Read More

J Cancer 2018 20;9(22):4197-4203. Epub 2018 Oct 20.

Department of Abdominal Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, China.

Whether metastasectomy improves prognosis of gastric cancer patients with ovarian metastases (Krukenberg tumors) is not clear. In this study, we examined the survival benefit of metastasectomy combined with chemotherapy for treatment of synchronous Krukenberg tumors from gastric cancer and identified the prognostic factors. The subjects of this study were patients diagnosed as synchronous Krukenberg tumors of gastric origin in the period between December 2004 and December 2015. Read More

J Inflamm Res 2018 13;11:447-456. Epub 2018 Nov 13.

Department of Emergency, Qilu Hospital, Shandong University, Jinan, China,

Background: The incidence of recurrent cardiovascular events from the progression of nontarget lesions (NTLs) is high for percutaneous coronary intervention-treated patients. However, the underlying mechanisms have not been thoroughly elucidated.

Methods: In this study, ten atherosclerotic rabbits with multiple plaques in the upper and lower segments of abdominal aorta (group A) were randomly divided into two subgroups: group A1 underwent intravascular ultrasound examination and stent implantation in the lower segments of the abdominal aorta (n=5), whereas group A2 was without stenting (n=5). Read More

Onco Targets Ther 2018 12;11:8015-8024. Epub 2018 Nov 12.

Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China,

Purpose: This study mapped the localization of regional nodal recurrence to determine whether the clinical target volume (CTV) should be redefined in adjuvant radiotherapy.

Patients And Methods: Between January 2004 and October 2015, a total of 129 patients with gastric cancer following D2 resection who experienced regional recurrence were retrospectively examined. The lymph nodes (LNs) were hand-drawn proportionally on template computed tomography (CT) images of a standard patient by referencing surrounding anatomic landmarks. Read More

Nat Rev Cardiol 2018 Dec 5. Epub 2018 Dec 5.

Nature Reviews Cardiology, .

Nature 2018 Dec 5. Epub 2018 Dec 5.

Department of Anaesthesiology, University Hospital, LMU Munich, Munich, Germany.

Heart transplantation is the only cure for patients with terminal cardiac failure, but the supply of allogeneic donor organs falls far short of the clinical need. Xenotransplantation of genetically modified pig hearts has been discussed as a potential alternative. Genetically multi-modified pig hearts that lack galactose-α1,3-galactose epitopes (α1,3-galactosyltransferase knockout) and express a human membrane cofactor protein (CD46) and human thrombomodulin have survived for up to 945 days after heterotopic abdominal transplantation in baboons. Read More

Clin Chem 2018 Dec 5. Epub 2018 Dec 5.

Cardiovascular Research Institute Basel (CRIB), Basel, Switzerland.

Background: The early diagnosis of urgent abdominal pain (UAP) is challenging. Most causes of UAP are associated with extensive inflammation. Therefore, we hypothesized that quantifying inflammation using interleukin-6 and/or procalcitonin would provide incremental value in the emergency diagnosis of UAP. Read More

Expert Rev Med Devices 2018 Dec 6. Epub 2018 Dec 6.

a Department of Vascular Surgery , "Democritus" University of Thrace, University Hospital of Alexandroupolis , Greece.

Introduction: The Ovation stent-graft uncouples the steps of fixation and sealing via a pair of polymer-filled inflatable rings. Apart from the well-documented early results, newer data emerged for mid-term results of Ovation and are presented in this review. Areas covered: Aim of this article was to report all current studies with the mid-term results of the particular endograft, the incidence of complications and failure and discuss their management. Read More

Avian Pathol 2018 Dec 6:1-27. Epub 2018 Dec 6.

c 138 Hartford Road, Huntingdon, Cambridgeshire , PE29 1XQ , UK .

In an initial study in SPF chickens, a heterologous virus neutralising (VN) antibody response to IBV variants Q1, Variant 2 (Var 2), D388/QX (D388), D274 and Arkansas (DPI) was observed using a vaccination programme incorporating two different live-attenuated IBV vaccines, followed by boosting with an inactivated vaccine containing IBV Massachusetts (Mass) antigen. Therefore, a more detailed study was undertaken in SPF layer-type chickens previously primed with IBV Mass and 793B live-attenuated vaccines. The efficacy of single or repeated vaccination with a multivalent inactivated vaccine containing IBV antigen was determined against challenge with 5 virulent IBVs: Mass (M41), 793B (4/91), D388, Q1 and Var 2. Read More

Gen Comp Endocrinol 2018 Nov 30. Epub 2018 Nov 30.

College of Animal Science and Technology, Shandong Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, No. 61 Daizong Street, Taian, 271018, PR China. Electronic address:

Ghrelin, one of the most important appetite regulating peptides, is involved in the regulation of energy homeostasis. The anorexia effect of ghrelin in chickens is contrary to that of ghrelin in mammals. In the present study, the effects of feeding status and dietary energy level on plasma total ghrelin levels and expression were studied in broilers. Read More

Microsurgery 2018 Dec 3. Epub 2018 Dec 3.

Department of Plastic, Reconstructive, Aesthetic Surgery and Burns, CHRU Rangueil, Toulouse, France.

Background: Extensive full thickness abdominopelvic defects pose a difficult challenge to surgeons. Autologous tissues are versatile and can provide a satisfying reconstructive option for this type of defects. The tensor fascia latae (TFL) and superficial circumflex iliac perforator (SCIP) flaps provide a large area of vascularized tissue and their use in reconstructive surgery is well-known. Read More

Dev Med Child Neurol 2018 Dec 3. Epub 2018 Dec 3.

Department of Physiotherapy, Monash University, Frankston, Victoria, Australia.

Aim: The primary aim of this review is to evaluate the evidence for pain prevalence in children and young adults with cerebral palsy. Secondary aims are to identify pain characteristics and types of pain measurement used in this population.

Method: Ovid MEDLINE, Embase, CINAHL Plus, and PubMed were searched in October 2016 and updated in November 2017. Read More

Radiat Prot Dosimetry 2018 Dec 1. Epub 2018 Dec 1.

Radiography & Diagnostic Imaging, School of Medicine, University College Dublin, Dublin, Ireland.

The aim of this study was to evaluate how iterative reconstruction can compensate for the noise increase in low radiation dose abdominal computed tomography (CT) technique for large size patients and the general impact of obesity on abdominal organ doses and image quality in CT. An anthropomorphic phantom layered with either none or a single layer of 3-cm- thick circumferential animal fat packs to simulate obese patients was imaged using a 128MDCT scanner. Abdominal protocols (n = 12) were applied using automatic tube current modulation (ATCM) with various quality reference mAs (150, 200, 250 and 300). Read More

Carcinogenesis 2018 Dec 2. Epub 2018 Dec 2.

Department of Pathology, School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas USA.

Kidneys are one of the main dose-limiting organs in radio-therapeutic procedures of lower abdomen. Likewise, the threat of exposure of radio-sensitive organs such as kidneys in warfare or radiation accidents among military personal or due to terrorist activities in general public is of increasing concern. These events warrant the need for appropriate animal models to study the acute and chronic effects of low and high dose rate radiation exposures. Read More

Genet Mol Biol 2018 Nov 23. Epub 2018 Nov 23.

Laboratório de Polimorfismos e Ligação, Departamento de Genética, Universidade Federal do Paraná (UFPR) Curitiba, PR, Brazil.

Genes can influence lipid profile and anthropometric variables related to obesity. The present study aimed to verify if variants of the APOE, APOB, ADIPOQ, HSD11β1, and PLIN4 genes are associated with lipid levels or anthropometric variables in a sample comprised of 393 Euro-Brazilian children and adolescents. DNA was genotyped by TaqMan allelic discrimination assay. Read More

Medwave 2018 Oct 16;17(6):e7288. Epub 2018 Oct 16.

Consulta Externa de Nutrición Clínica, Hospital Médica Sur, Tlalpan, México. Address: Puente de Piedra 150, Toriello Guerra, Tlalpan, Ciudad de México, México, CP: 14050. Email:

Introduction: Chronic diseases are on the rise and are associated with weight gain. Multidisciplinary strategies are required for its control.

Methods: The design was descriptive, observational and retrospective. Read More

J Trauma Acute Care Surg 2018 Nov 30. Epub 2018 Nov 30.

Royal Canadian Medical Service, Ottawa, ON, Canada.

Background: Junctional tourniquets have been incorporated into tactical combat casualty care for junctional vascular trauma. They apply external compression to stop blood flow in the groin and axilla.

Objectives: The primary outcome was effectiveness in achieving arterial occlusion. Read More

Curr Opin Anaesthesiol 2018 Nov 29. Epub 2018 Nov 29.

Department of Vascular Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

Purpose Of Review: Spinal cord ischemia (SCI) is a devastating complication after open or endovascular aortic repair for thoracoabdominal aortic disease. The underlying pathogenesis is not fully understood but appears multifactorial. Multiple spinal cord protection strategies and monitoring techniques are currently utilized with variable results seen. Read More

Acta Cardiol 2018 Dec 3:1-7. Epub 2018 Dec 3.

a Dipartimento di Medicina Interna e Scienze Biomediche, Sezione di Cardiologia , Università degli Studi di Parma , Parma , Italy.

Background: We aimed to depict the electrocardiographic and echocardiographic aspects in patients before elective major vascular surgery.

Methods: We evaluated through standard 12 lead electrocardiography and transthoracic echocardiography 469 patients with asymptomatic large abdominal aortic aneurysm (AAA), 334 with critical carotid stenosis (CAS), and 238 with advanced peripheral artery disease (PAD) before surgical revascularization.

Results: Patients with AAA were predominantly males (p < . Read More

Am J Physiol Heart Circ Physiol 2018 Dec 28;315(6):H1735-H1747. Epub 2018 Sep 28.

Department of Biomedical Sciences, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, New York.

Overconsumption of a diet rich in fat and carbohydrates, called the Western diet, is a major contributor to the global epidemic of cardiovascular disease. Despite previously documented cardiovascular protection exhibited in female rats, this safeguard may be lost under certain metabolic stressors. We hypothesized that female Wistar rats challenged by a Western diet composed of 21% fat and 50% carbohydrate (34. Read More

Br J Surg 2018 Dec 3. Epub 2018 Dec 3.

Department of Oncology, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway.

Background: According to guidelines, adjuvant treatment or re-excision should be considered after R1 resection of gastrointestinal stromal tumours (GISTs). However, the prognostic significance of R1 resection is uncertain and tumour rupture confounds its assessment. Here, the impact of positive margins was examined and related to rupture in a population-based cohort. Read More