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BMJ Case Rep 2022 Jun 28;15(6). Epub 2022 Jun 28.

Obstetrics and Gynaecology, Hospital Pedro Hispano, Matosinhos, Portugal.

Ann Vasc Surg 2022 Jun 25. Epub 2022 Jun 25.

Sorbonne Université, UPMC Univ Paris 06, Paris, France; Service de chirurgie vasculaire et endovasculaire, Bâtiment Husson Mourier, CHU Pitié-Salpêtrière, 83 Bd de L'Hôpital, 75013, Paris.

Introduction: When best medical treatment fails to relieve symptoms of aorto-iliac occlusive disease (AIOD), endovascular treatment or conventional open surgery are the remaining options depending on lesions and patients' characteristics. However, in certain situations both endovascular tools and abdominal aorta to bi-femoral bypass are not an option and the use of the descending thoracic aorta may be considered as an inflow site for revascularization.

Methods: This work is a single center retrospective study. Read More

Int J Surg Case Rep 2022 Jun 16;96:107315. Epub 2022 Jun 16.

Department of General Surgery, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Laboratory of Anatomy, Microsurgery and Surgery, Experimental and Medical Simulation (LAMCESM), Mohammed Ist University, Oujda, Morocco.

Introduction: Spleen Spontaneous Rupture SRS is a rare phenomenon in which the spleen ruptures without associated trauma. This pathology is rarely caused by Chronic Lymphocytic Leukemia.

Presentation Of The Case: We present a case of a 59-year-old male patient with chronic Lymphocytic Leukemia, who was admitted with an acute abdomen whose clinical and paraclinical examinations revealed a spleen spontaneous rupture. Read More

Int J Surg Case Rep 2022 Jun 24;96:107346. Epub 2022 Jun 24.

Department of Pathology, Shree Birendra Hospital, Chhauni, Kathmandu 44600, Nepal.

Introduction And Importance: Colon cancer presenting as spontaneous enterocutaneous fistula are rare with only few cases reported in the literature. Such presentation signifies locally advanced disease with poorer outcomes. Enterocutaneous fistula increases morbidity and mortality in cancer and may potentially delay the definitive care. Read More

Asian Pac J Cancer Prev 2022 Jun 1;23(6):2159-2167. Epub 2022 Jun 1.

Department of Physics, School of Advanced Sciences, Vellore Institute of Technology, Vellore, India.

Background: A new VMAT method called "Augmented Arc" (or simply Aug Arc) is proposed. The aim of this study is to demonstrate the validity of the proposed method in different clinical cases. Basically, Aug Arc refers to the portion(s) of the VMAT arc that is augmented with an additional arc to improve the plan quality. Read More

Med Sci Sports Exerc 2022 Jun 24. Epub 2022 Jun 24.

Department of Psychology, Northeastern University, Boston, MA.

Purpose: Childhood obesity is a global health concern, with >340 million youth considered overweight or obese. In addition to contributing greatly to health care costs, excess adiposity associated with obesity is considered a major risk factor for premature mortality from cardiovascular and metabolic diseases, and is also negatively associated with cognitive and brain health. A complementary line of research highlights the importance of cardiorespiratory fitness, a byproduct of engaging in physical activity, on an abundance of health factors, including cognitive and brain health. Read More

Nutr Health 2022 Jun 28:2601060221097459. Epub 2022 Jun 28.

Neurologist, Neurology Unit, Department of Medicine, Hospital Sultanah Nur Zahirah, Jalan Sultan Mahmud, 20400 Kuala Terengganu, 26691Ministry of Health, Malaysia.

Stroke survivors are at high risk for recurrent cardiovascular events if no prevention strategies are undertaken This study aimed to investigate the fasting serum lipid profiles and lifestyle habits in stroke survivors, and the factors associated with suboptimal lipid profiles. A cross-sectional retrospective study was conducted in three public hospitals in Malaysia. Stroke survivors' data regarding the socio-demographic characteristics, clinical profiles, fasting serum lipid profiles, dietary adherence, and physical activity levels were acquired. Read More

Clin Pharmacokinet 2022 Jun 28. Epub 2022 Jun 28.

Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.

Objective: Upacicalcet is a new renally excreted and injectable calcimimetic agent. We evaluated the pharmacokinetics, pharmacodynamics, safety, and tolerability of single and multiple intravenous administration of upacicalcet in patients with secondary hyperparathyroidism undergoing hemodialysis.

Methods: This study was a multicenter, randomized, placebo-controlled, double-blinded, dose-escalation study consisting of a single-dose study and a multiple-dose study. Read More

Ann Surg Oncol 2022 Jun 28. Epub 2022 Jun 28.

Department of Gastroenterological Surgery, Yokohama City University School of Medicine, Yokohama City, Kanagawa, Japan.

Background: Prophylactic splenectomy for hilar lymph node (#10) dissection has shown no survival benefit for patients with proximal advanced gastric cancer that does not invade the greater curvature. However, the survival benefit of prophylactic splenectomy for proximal advanced gastric cancer invading the greater curvature side, particularly for clinically negative #10 lymph node metastasis (#10[-]) cases remains controversial.

Methods: This multi-institutional retrospective study enrolled 146 consecutive patients with proximal advanced gastric cancers invading the greater curvature side with clinical #10(-) who underwent R0 total gastrectomy. Read More

Clin J Gastroenterol 2022 Jun 28. Epub 2022 Jun 28.

Department of Gastroenterology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.

A 77-year-old woman with obstructive jaundice due to pancreatic head tumor was admitted to our hospital for biliary drainage. Transpapillary biliary drainage was attempted using endoscopic retrograde cholangiopancreatography; however, the catheter could not be inserted into the bile duct. Endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) was conducted using a 7-Fr plastic stent. Read More

Eur Radiol 2022 Jun 28. Epub 2022 Jun 28.

Department of Radiology, University of Bourgogne Franche-Comté, CHRU Besançon, Hôpital Jean Minjoz, 3 Boulevard Fleming, 25030, Besançon, France.

Objectives: The purpose of this study was to identify the preoperative CT features that are associated with inadvertent enterotomy (IE) during adhesive small bowel obstruction (ASBO) surgery.

Methods: From January 2015 to December 2019, all patients with ASBO who underwent an abdominal CT were reviewed. Abdominal CT were retrospectively reviewed by two radiologists with a consensus read in case of disagreement. Read More

Eur Radiol 2022 Jun 28. Epub 2022 Jun 28.

The First Health Care Department, The Second Medical Center & National Clinical Research Center for Geriatric disease, Chinese PLA general Hospital, Beijing, 100853, People's Republic of China.

Objectives: To compare the efficacy of transarterial embolization (TAE) with polyvinyl alcohol (PVA) particles alone and lipiodol-bleomycin emulsion (LBE) plus PVA particles for patients with unresectable large symptomatic focal nodular hyperplasia (FNH).

Methods: We performed a retrospective analysis of patients who underwent TAE either with PVA particles alone (group A, n = 46) or LBE plus PVA particles (group B, n = 35) for large (≥ 7 cm) symptomatic FNH between January 2002 and February 2019. Propensity score matching (PSM) (1:1) was performed to adjust for potential baseline confounders. Read More

J Clin Endocrinol Metab 2022 Jun 28. Epub 2022 Jun 28.

Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China. Key Laboratory of Public Health Safety (Fudan University), Ministry of Education, China.

Context: Findings of observational studies indicated an association of thyroid hormone levels with the risk of nonalcoholic fatty liver disease (NAFLD), whereas conflicting results remained and might be subject to reverse causality.

Objective: This study aimed to evaluate the associations between NAFLD and both plasma thyroxine (T4) and thyroid stimulating hormone (TSH) at the phenotypic and genetic levels.

Methods: We included 14,797 participants, aged 20 - 74 years and had undergone abdominal ultrasonography during the Third National Health and Nutrition Examination Survey (NHANES III). Read More

JAAPA 2022 Jul;35(7):46-51

Mayur Virarkar is an assistant professor in the Division of Abdominal and General Body Imaging at the University of Florida College of Medicine in Jacksonville, Fla. Joseph A. Coleman is a student at the University of Houston in Houston, Tex. At the University of Texas' MD Anderson Cancer Center in Houston, Zeeshan A. Siddiqui is a project director in the Department of Ambulatory Operation and Access, Viola B. Leal is a program manager, Angel E. McClinton practices in surgical oncology, Joseph R. Steele is an interventional radiologist, Wei Yang is a professor and chair of the Department of Diagnostic Radiology, Priya Bhosale is a professor in the departments of diagnostic radiology and abdominal imaging, and Albert R. Klekers is an assistant professor in the Department of Abdominal Radiology. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Objective: To evaluate the effects on efficiency and patient care of the addition of physician assistants (PAs) and NPs to the abdominal radiology consult service.

Methods: We obtained radiologist productivity and patient care metrics for 3 months before and 3 months after the integration of PAs and NPs into our consult service.

Results: Integrating PAs and NPs into the workflow led to a significant increase in mean RVUs/shift (15. Read More

Antimicrob Agents Chemother 2022 Jun 28:e0041922. Epub 2022 Jun 28.

UQ Centre for Clinical Research, Faculty of Medicine, The University of Queenslandgrid.1003.2, Herston, Queensland, Australia.

Guidelines for surgical prophylactic dosing of cefazolin in bariatric surgery vary in terms of recommended dose. This study aimed to describe the plasma and interstitial fluid (ISF) cefazolin pharmacokinetics in patients undergoing bariatric surgery and to determine an optimum dosing regimen. Abdominal subcutaneous ISF concentrations (measured using microdialysis) and plasma samples were collected at regular time points after administration of cefazolin 2 g intravenously. Read More

Ther Adv Cardiovasc Dis 2022 Jan-Dec;16:17539447221107737

Department of Radiology, Keck School of Medicine, University of Southern California, 2250 Alcazar Street, CSC Room 104, Los Angeles, CA 90033, USA.

Intracardiac thrombus in the left atrium and atrial appendage (LA/LAA) and left ventricle (LV) increases the risk of systemic thromboembolism and causes potentially devastating diseases such as ischemic stroke and acute ischemia in abdominal organs and lower extremities. Detecting the presence and monitoring the resolution of left heart intracardiac thrombus are of vital importance for stratifying patients and guiding treatment decisions. Currently, echocardiography is the most frequently used method for the above clinical needs, followed by computed tomography. Read More

Q J Nucl Med Mol Imaging 2022 Jun 28. Epub 2022 Jun 28.

Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.

Background: To investigate the clinical, hematological and biochemical toxicity differences between glass and resin yttrium-90 (90Y)-microspheres radioembolization treatment of primary and metastatic liver disease.

Methods: Between May 2014 and November 2016 all consecutive glass and resin 90Y microspheres radioembolization treatments were retrospectively analyzed. Biochemical, hematological and clinical data were collected at treatment day, two weeks, one month and three months follow-up. Read More

Ann Surg 2022 Jun 28. Epub 2022 Jun 28.

Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI.

Objective: To determine cell-specific gene expression profiles that contribute to development of abdominal aortic aneurysms (AAAs).

Background: AAAs represent the most common pathological aortic dilation leading to the fatal consequence of aortic rupture. Both immune and structural cells contribute to aortic degeneration, however, gene specific alterations in these cellular subsets are poorly understood. Read More

Ann Surg 2022 Jun 28. Epub 2022 Jun 28.

Department of Abdominal Surgery and Transplantation, CHU Liege, Liege, Belgium.

Introduction: The incidence of incisional hernias (IHs) after open repair of an abdominal aortic aneurysm (AAA) is high. Several randomized controlled trials have reported favorable results with the use of prophylactic mesh to prevent IHs, without increasing complications. In this analysis we report on the results of the 60-month follow-up of the PRIMAAT trial (Ann Surg 2016; 263(4): 638-45). Read More

J Investig Med High Impact Case Rep 2022 Jan-Dec;10:23247096221109206

Texas Tech University Health Sciences Center El Paso, USA.

Acute intermittent porphyria (AIP) is a rare autosomal dominant inherited disease, predominantly seen in female patients, caused by mutations in the hydroxymethylbilane synthase gene. When impaired, elevated heme biosynthesis precursor levels accumulate in the liver, resulting in neurological symptoms, psychiatric disturbances, darkened urine color, abdominal pain, nausea, vomiting, and ileus. We present a 22-year-old Hispanic female with diffuse abdominal pain and no bowel movements for 8 days. Read More

Br J Radiol 2022 Jun 28:20220101. Epub 2022 Jun 28.

University of Health Sciences İstanbul Ümraniye Training and Research Hospital, Professor of Pediatric Rheumatology, Director of Pediatrics, İstanbul, Turkey.

Objective: To retrospectively evaluate the imaging and clinical findings of patients diagnosed with multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19.

Methods: The clinical, laboratory and radiological data of 110 patients (74 male and 36 female) diagnosed with COVID-19-related MIS-C between June 2020 and November 2021 were evaluated retrospectively. Cases with a diagnosis of MIS-C based on a positive real time polymerase chain reaction test (RT-PCR) or serology results according to the WHO criteria were included in the study. Read More

Eur J Pain 2022 Jun 28. Epub 2022 Jun 28.

Department of Anesthesiology, Hospital del Mar. IMIM (Hospital del Mar Medical Research Institute). Universitat Autònoma de Barcelona, Spain.

Background: Identifying predictors of poor postoperative outcomes is crucial for planning personalized pain treatments. The aim of this study was to examine pain outcomes using cluster analysis in N=2,678 patients from the PAIN-OUT registry at first postoperative day.

Methods: Indicator variables of the clustering analysis assessed multiple domains, such as clinical and surgical conditions, analgesic-anesthetic variables, desire for more pain treatment and outcome variables of the International Pain Outcome Questionnaire (IPO) summarized as factor scores. Read More

J Vet Diagn Invest 2022 Jun 27:10406387221106252. Epub 2022 Jun 27.

Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT, USA.

A 10.5-y-old intact female capybara () with a history of chronic weight loss was euthanized following discovery by palpation of a large intra-abdominal mass. Postmortem examination revealed a large, firm, tan mass expanding the uterine body and extensively adhered to the jejunum and abdominal wall. Read More

European J Pediatr Surg Rep 2022 Jan 25;10(1):e80-e83. Epub 2022 Jun 25.

Department of Pediatric Surgery, Hacettepe Universitesi Tip Fakultesi, Ankara, Turkey.

The fusion of gonadal structures with internal organs is very rare. The close proximity between the left gonad and spleen during embryogenesis may result in splenogonadal fusion (SGF). Moreover, the trapping of hepatocyte-destined mesenchyme cells in gonads is defined as hepatogonadal fusion (HGF). Read More

European J Pediatr Surg Rep 2022 Jan 25;10(1):e76-e79. Epub 2022 Jun 25.

Department of Pediatric Surgery, Division of Vascular Anomalies, La Paz Children's Hospital, Madrid, Spain.

Congenital infantile fibrosarcoma (CIF) is a rare tumor in children that occurs in the first years of life. It usually arises in the extremities but some cases affect the trunk, neck, abdomen, or retroperitoneum. Surgical resection has been traditionally the treatment of choice but the development of genomic analysis and targeted therapies has shed light on new therapeutic options. Read More

Mol Clin Oncol 2022 Jul 7;17(1):122. Epub 2022 Jun 7.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan, R.O.C.

The present report described the case of a 71-year-old man who was admitted to the emergency department with a 7-day history of progressive left flank pain and tarry stool. Bedside point-of-care ultrasound of the left kidney showed lobulated ill-defined hypoechoic foci in the perirenal spaces with mild hydronephrosis. Subsequent contrast-enhanced abdominal computed tomography revealed lobulated low-density lesions in the bilateral perirenal space and paraaortic space. Read More

Clin Cosmet Investig Dermatol 2022 21;15:997-1019. Epub 2022 Jun 21.

Behavior, Paris, France.

The number of aesthetic procedures performed worldwide continues to grow together with an increase in the population seeking the restoration or preservation of a youthful appearance. Requests for non-surgical body rejuvenation are increasing. Patients are looking for safe and effective minimally invasive aesthetic procedures. Read More

Gastroenterol Res Pract 2022 18;2022:8379579. Epub 2022 Jun 18.

Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens 15784, Greece.

The aim of this study was to investigate the relationship between gastrointestinal (GI) symptoms and extragastric manifestations such as headache, fatigue, and dizziness. A prospective cohort study was conducted in a tertiary hospital in Athens, where patients with GI problems and extragastric symptoms were treated only for their GI problems, and improvement in extragastric manifestations was recorded. Inclusion criteria were an age older than 18 years, the presence of at least one of the three extragastric symptoms investigated in this study (headache, dizziness, and fatigue), and the concomitant presence of at least one gastrointestinal symptom (e. Read More

Exp Ther Med 2022 Jul 1;24(1):482. Epub 2022 Jun 1.

Laboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece.

The novel coronavirus has negatively affected patients and healthcare systems globally. Individuals with coronavirus disease 2019 (COVID-19) experience a wide range of respiratory symptoms, from mild flu-like symptoms to severe and potentially fatal pneumonia. Some patients report gastrointestinal symptoms, such as nausea, vomiting and abdominal pain in addition to the respiratory symptoms or as a separate presentation. Read More

IDCases 2022 18;29:e01541. Epub 2022 Jun 18.

Division of Clinical Care and Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

With increased use of disease-modifying antirheumatic drugs, screening for latent tuberculosis infection is more important than ever. However, even with appropriate screening, reactivation of tuberculosis can occur in patients who have had significant epidemiological exposures. Herein, we present a case of a seventy-four-year-old woman with severe rheumatoid arthritis on long-term disease-modifying antirheumatic drugs who developed cryptic miliary tuberculosis. Read More