422,323 results match your criteria Abdominal Imaging [Journal]


Porcine-Derived Biomaterials in Tissue Engineering and Reconstructive Surgery: Considerations and Alternatives in Muslim Patients.

J Tissue Eng Regen Med 2018 Dec 16. Epub 2018 Dec 16.

Department of Plastic Surgery, Hand Surgery and Burn Centre, Faculty of Medicine, RWTH University Hospital, Aachen, Germany.

During the last three decades, tissue engineering and reconstructive surgery have become standard therapeutic options in the world of medicine. Several biomaterials, either alone, or in combination with cultured cellular products, have been introduced to compensate for the scarcity of autologous donor tissue or to improve healing in a variety of surgical specialties e.g. Read More

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December 2018

Deficiencies in postoperative surveillance for veterans with gastrointestinal cancer.

J Surg Oncol 2018 Dec 16. Epub 2018 Dec 16.

Department of Surgery, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin.

Background And Objectives: National guidelines for gastrointestinal (GI) cancers offer surveillance algorithms to facilitate detection of recurrent disease, yet adherence rates are unknown. We sought to characterize postoperative surveillance patterns for veterans with GI cancer at a tertiary care Veterans Affairs Hospital.

Methods: A single-center retrospective cohort study identified patients who underwent surgical resection for colorectal, gastroesophageal or hepatopancreaticobiliary malignancy from 2010-2016. Read More

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December 2018

Red flags for appropriate referral to the gastroenterologist & rheumatologist of patients with inflammatory bowel disease & spondyloarthritis.

Clin Exp Immunol 2018 Dec 15. Epub 2018 Dec 15.

IBD Unit, Presidio Columbus, Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, Rome, Italy.

Collaboration between gastroenterologists and rheumatologists is recommended for correct management of patients with associated spondyloarthritis (SpA) and inflammatory bowel disease (IBD). We aimed to establish the appropriateness of several red flags for a prompt specialist referral. A systematic review of the literature was performed using the GRADE method to describe the prevalence of coexisting IBD-SpA and the diagnostic accuracy of red flags proposed by a steering committee. Read More

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December 2018

The effects of a 12-week jump rope exercise program on abdominal adiposity, vasoactive substances, inflammation, and vascular function in adolescent girls with prehypertension.

Eur J Appl Physiol 2018 Dec 15. Epub 2018 Dec 15.

Department of Physical Education, Pusan National University, Busan, South Korea.

Introduction: Childhood obesity is strongly associated with cardiovascular disease (CVD) development. It is necessary to combat unfavorable outcomes of obesity at a young age by utilizing effective interventions, such as exercise.

Purpose: We sought to examine the effects of a jump rope exercise program on CVD risk factors, including body composition, vasoactive substances, inflammation, and vascular function in prehypertensive adolescent girls. Read More

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December 2018
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Consensus Statement of the Italian Society of Colorectal Surgery (SICCR): management and treatment of complete rectal prolapse.

Tech Coloproctol 2018 Dec 15. Epub 2018 Dec 15.

Department of Colorectal Surgery, Santa Rita Clinic, Vercelli, Italy.

Rectal prolapse, rectal procidentia, "complete" prolapse or "third-degree" prolapse is the full-thickness prolapse of the rectal wall through the anal canal and has a significant impact on quality of life. The incidence of rectal prolapse has been estimated to be approximately 2.5 per 100,000 inhabitants with a clear predominance among elderly women. Read More

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December 2018
1 Read

Giant-cell arteritis without cranial manifestations presenting as fever of unknown origin: a diagnostic value of 18F-FDG PET/CT.

Clin Ter 2018 Nov-Dec;169(6):e274-e276

Department of Infectious Diseases, Military Medical Academy, Sofia, Bulgaria.

We present a case of 68-year-old female with four months history of fever, fatigue, and weight loss. She was classified as case of fever of unknown origin. The physical examination was normal, the laboratory tests showed anemia, elevation of C-reactive protein, erythrocyte sedimentation rate and fibrinogen. Read More

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December 2018
3 Reads

Isolated Ascites in a Monochorionic Twin after Fetoscopic Laser Ablation Is Not Necessarily Secondary to Recurrence or Anaemia: Bowel Complications in Twin-to-Twin Transfusion Syndrome after Fetoscopic Laser Ablation.

Fetal Diagn Ther 2018 Dec 14:1-10. Epub 2018 Dec 14.

Fetal Medicine Centre, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, United Kingdom.

Background/purpose: We report a case study of jejunal atresia and the results of a systematic literature review of all reported cases of bowel complications occurring after fetoscopic laser ablation (FLA) for the treatment of twin-to-twin transfusion syndrome (TTTS).

Methods: A systematic literature review was performed of bowel complications after FLA for TTTS according to PRISMA guidelines.

Results: There are 11 published cases of small bowel atresia, 5 cases of necrotising enterocolitis (NEC), and 2 cases with foetal bowel perforations. Read More

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December 2018

Is There A Relation Between Serum Uric Acid Values and Prostatic Calculi Presence?

Urol Int 2018 Dec 14:1-6. Epub 2018 Dec 14.

Department of Radiology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.

Objective: We planned to examine the connection between serum uric acid (UA) values and prostatic calculi (PCal) presence and to evaluate the relation between PCal and other etiological factors.

Methods: Patients between 20 and 60 years of age who were referred to the clinic with any reason and had non-contrast abdominal tomography (NCACT) for PCal were included in the study. While the patients were separated into 2 groups based on their serum UA level as ≥7 mg/dL (Group 1) and < 7 mg/dL (Group 2), NCACT was also divided into 2 groups as PCal presence (PCal+) and lack (PCal-) serum UA, calcium, phosphorus, sodium, prostate-specific antigen levels and urinary analysis results of the patients were evaluated and compared. Read More

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December 2018

CRISPR/Cas9 deletions in a conserved exon of Distal-less generates gains and losses in a recently acquired morphological novelty in flies.

iScience 2018 Dec 1;10:222-233. Epub 2018 Dec 1.

Department of Biological Sciences, National University of Singapore, Singapore, Singapore. Electronic address:

Distal-less has been repeatedly co-opted for the development of many novel traits. Here, we document its curious role in the development of a novel abdominal appendage ("sternite brushes") in sepsid flies. CRISPR/Cas9 deletions in the homeodomain result in losses of sternite brushes, demonstrating that Distal-less is necessary for their development. Read More

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December 2018

Standard and viscoelastic mechanical properties of respiratory system compartments in dogs: effect of volume, posture, and shape.

Respir Physiol Neurobiol 2018 Dec 13. Epub 2018 Dec 13.

Department of Physiopathology and Transplantations, Università degli Studi di Milano, Milan, Italy.

In 9 anesthetized, paralyzed dogs lung and chest-wall standard (viscous resistance, Rint, and quasi-static elastance, Est) and viscoelastic parameters (resistance, Rvel, and time constant, τvel) were measured in the supine posture before and after rib-cage block, after application of an expiratory threshold load, and after 75° head-up tilting before and after wide chest opening. Lung and chest-wall τvel were the same under all conditions. Rvel was independent of volume and posture, and greater for the lung. Read More

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December 2018

Using bifurcated endoprosthesis after iliac artery recanalization for concomitant abdominal aortic aneurysm and chronic total occlusions of access routes.

J Vasc Surg 2018 Dec 12. Epub 2018 Dec 12.

Division of Vascular Surgery, Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.

Objective: Concurrent abdominal aortic aneurysm (AAA) and unilateral iliac occlusion is a challenge in the implantation of bifurcated stent grafts (BFGs). The endovascular approach is less invasive than open surgery; the aortouni-iliac (AUI) graft with crossover femorofemoral bypass (CFFB) has many problems associated with extra-anatomic reconstruction. We attempted endovascular aneurysm repair (EVAR) using BFGs in such cases and evaluated the outcomes. Read More

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December 2018

Fenestrated endovascular aneurysm repair is associated with lower perioperative morbidity and mortality compared with open repair for complex abdominal aortic aneurysms.

J Vasc Surg 2018 Dec 12. Epub 2018 Dec 12.

Division of Vascular and Endovascular Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass. Electronic address:

Objective: The Zenith Fenestrated Endovascular Graft (ZFEN; Cook Medical, Bloomington, Ind) has expanded the anatomic eligibility of endovascular aneurysm repair (EVAR) for complex abdominal aortic aneurysms (AAAs). Current data on ZFEN mainly consist of single-institution experiences and show conflicting results. Therefore, we compared perioperative outcomes after repair using ZFEN with open complex AAA repair and infrarenal EVAR in a nationwide multicenter registry. Read More

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December 2018

An unusual case of gastrointestinal basidiobolomycosis mimicking colon cancer; literature and review.

J Mycol Med 2018 Dec 12. Epub 2018 Dec 12.

Department of Medical Mycology/Invasive Fungi Research Center, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address:

Gastrointestinal basidiobolomycosis (GIB), a rare fungal infection associated with high mortality, has been reported worldwide mainly from tropical and subtropical regions of Asia, USA, and Latin America. The clinical manifestations are highly diverse and non-specific depending on the underlying disease, but fever, abdominal pain, weight loss, diarrhea, constipation and chills have been observed. There are no prominent risk factors for GIB but climatic conditions and life style are related to this infection in arid and semi-arid regions. Read More

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December 2018

Preoperative Low-dose and High-dose Pregabalin and Cardiovascular Response to Endotracheal Intubation: A Prospective, Randomized, Single-blind, Controlled Study in China.

Clin Ther 2018 Dec 12. Epub 2018 Dec 12.

Department of Anesthesiology, Qingpu Branch of Zhongshan Hospital affiliated with Fudan University, Shanghai, China.

Purpose: A prospective, randomized, single-blind, controlled clinical study was designed to evaluate the efficacy and tolerability of preoperative pregabalin on cardiovascular response to laryngoscopy and endotracheal intubation.

Methods: Patients aged 18-60 years with an American Society of Anesthesiologists scale score of I or II were recruited and randomly allocated to receive placebo (control), low-dose (150-mg) pregabalin, or high-dose (300-mg) pregabalin. The medications were orally administered 1 hour before general anesthesia. Read More

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December 2018

How I do it: Surgically inserted transversus abdominis plane (TAP) catheters for flank incisions.

Can J Urol 2018 Dec;25(6):9623-9626

Department of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, Alberta, Canada.

Pain control following major abdominal surgery remains a significant barrier to patient comfort. Although thoracic epidurals have been used to provide analgesia for these surgeries, the transversus abdominis plane (TAP) block is gaining popularity. The TAP catheter insertion method has transformed over the past two decades from a blinded technique to one conducted primarily under ultrasound guidance by anesthesiologists. Read More

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December 2018

Incisional hernia after cystectomy: incidence, risk factors and anthropometric predisposition.

Can J Urol 2018 Dec;25(6):9573-9578

Department of Urology, Hahnemann University Hospital/Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.

Introduction: Postoperative incisional hernias (PIH) are an established complication of abdominal surgery with rates after radical cystectomy (RC) poorly defined. The objective of this analysis is to compare rates and risk factors of PIH after open (ORC) and robotic-assisted (RARC) cystectomy at a tertiary-care referral center.

Materials And Methods: We performed a retrospective review of patients undergoing ORC and RARC from 2000-2015 with pre and postoperative cross-sectional imaging available. Read More

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December 2018

Risk factors for mortality and cost implications of complicated intra-abdominal infections in critically ill patients.

J Crit Care 2018 Dec 12;50:169-176. Epub 2018 Dec 12.

Dipartimento di Scienza dell'Emergenza, Anestesiologiche e della Rianimazione - UOC di Anestesia, Rianimazione, Terapia Intensiva e Tossicologia Clinica - Istituto di Anestesia e Rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma - Università Cattolica del Sacro Cuore, Italy. Electronic address:

Purpose: To assess risk factors for 28-day mortality and cost implications in intensive care unit (ICU) patients with complicated intra-abdominal infections (cIAIs).

Methods: Single-center retrospective cohort study of prospectively collected data analysing ICU patients with a microbiologically confirmed complicated intra-abdominal infections.

Results: 137 complicated intra-abdominal infections were included and stratified according to the adequacy of antimicrobial therapy (initial inadequate antimicrobial therapy [IIAT], n = 44; initial adequate antimicrobial therapy [IAAT], n = 93). Read More

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December 2018

Mesenchymal stromal cells isolated from human fetal liver release soluble factors with a potential role in liver tissue repair.

Differentiation 2018 Dec 5;105:14-26. Epub 2018 Dec 5.

Department of Research, IRCCS-ISMETT, Palermo, Italy.

We isolated a population of proliferating cells from cultured human fetal hepatocytes of 16-22 weeks gestational age. The cells shared a similar phenotype to that of mesenchymal stromal cells (MSCs) according to the International Society for Cellular Therapy (ISCT), including plastic adherence, antigen expression profile, and in vitro multilineage differentiation potential. Fetal liver (FL)-MSCs expressed the albumin gene, and harbored a subpopulation of CK18 cells (20-40%), which defined their hepatic origin. Read More

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December 2018
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A case of completely isolated advanced enteric duplication cyst cancer performed partial pancreatectomy.

Int J Surg Case Rep 2018 Nov 27;54:83-86. Epub 2018 Nov 27.

Department of Gastroenterological Surgery, Higashiosaka City Medical Center, Nishiiwata 3-4-5, Higashiosaka, Osaka, 567-8588, Japan.

Introduction: Enteric duplication cysts are rare and, in addition, isolated enteric duplication cysts are lower morbidity prevalence rate. These cysts lack a connection to the gastrointestinal tract or the adjacent mesenteric vasculature and have only been reported in 10 case reports. In these reports, only two reports were cases with malignant transformation. Read More

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November 2018

Emex spinosa (L.) Campd. ethyl acetate fractions effects on inflammatory mediators and oxidative stressmarkers in carrageenan induced paw oedema in mice.

J Ethnopharmacol 2018 Dec 12. Epub 2018 Dec 12.

Biopesticides Laboratory (LPIP), Center of Biotechnology of Sfax, University of Sfax, P.O. Box. 1177, 3018 Sfax, TUNISIA. Electronic address:

Ethnopharmacological Relevance: Emex spinosa (L.) Campd. (E. Read More

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December 2018
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An Isolated Ureteropelvic Junction Injury Following a Low-Impact Mechanical Fall.

Urology 2018 Dec 12. Epub 2018 Dec 12.

University of Massachusetts Memorial Health Care.

Objective: To describe the presentation of a rare isolated ureteropelvic junction injury resulting from a mechanical fall on ice.

Materials And Methods: A 71-year-old previously healthy man presented to the emergency department at the University of Massachusetts Medical School three hours following falling on ice with complaints of gross hematuria and flank pain. Patient records were accessed via the institution's electronic medical records system between March 22, 2018 and April 22, 2018. Read More

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December 2018

Surgical outcomes of acute type A aortic dissection in dialysis patients.

Gen Thorac Cardiovasc Surg 2018 Dec 14. Epub 2018 Dec 14.

Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanumacho, Omiya-ku, Saitama, 330-8503, Japan.

Background: Acute type A aortic dissection (ATAAD) is relatively uncommon in dialysis patients, and characteristics and repair outcomes are not fully understood.

Patients And Methods: Patients with ATAAD (n = 960) were divided into a dialysis group (n = 19) and non-dialysis group (n = 941), depending on whether they required dialysis for preoperative end-stage renal disease (ESRD). Hospital charts and imaging data were reviewed, and characteristics and outcomes were compared between the groups. Read More

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December 2018

[The rich diversity of Whipple's disease].

Z Rheumatol 2018 Dec 14. Epub 2018 Dec 14.

Klinik für Rheumatologie, Immunologie und Osteologie, Krankenhaus St. Josef Wuppertal, Bergstr. 6-12, 42105, Wuppertal, Deutschland.

Whipple's disease (WD) is a rare, chronic multiorgan disease which can caused by Tropheryma whipplei, a ubiquitous gram positive bacterium. Detection of T. whipplei is mostly performed histologically using periodic acid-Schiff (PAS) staining in affected tissues to visualize characteristic PAS-positive macrophages and by the polymerase chain reaction (PCR). Read More

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December 2018

Radiographic stool quantification: an equivalence study of 484 symptomatic and asymptomatic subjects.

Abdom Radiol (NY) 2018 Dec 14. Epub 2018 Dec 14.

Department of Radiology, Michigan Medicine, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109, USA.

Purpose: To determine if symptomatic patients referred for radiographic stool quantification have equivalent stool burden to asymptomatic patients.

Method: This was an IRB-approved HIPAA-compliant retrospective equivalence cohort study. An a priori equivalence power calculation was performed. Read More

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December 2018

Survival after abdominal aortic aneurysm repair is affected by socioeconomic status.

J Vasc Surg 2018 Dec 11. Epub 2018 Dec 11.

Division of Vascular Surgery, Henry Ford Hospital, Detroit, Mich. Electronic address:

Objective: The association between socioeconomic status (SES) and outcome after abdominal aortic aneurysm (AAA) repair is largely unknown. This study aimed to determine the influence of SES on postoperative survival after AAA repair.

Methods: Patients undergoing surgical treatment of AAA at a tertiary referral center between January 1993 and July 2013 were retrospectively collected. Read More

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December 2018
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Epicardial pacemaker implantation in small animals.

J Vet Cardiol 2018 Dec 11. Epub 2018 Dec 11.

Department of Clinical Sciences, Colorado State University, Fort Collins, CO, 80525, USA. Electronic address:

Epicardial pacemaker implantation can be performed as a lone procedure or in combination with another thoracic or abdominal surgery. This article reviews the current literature and describes a minimally invasive approach for epicardial pacemaker implantation in small animals. The principal advantage of epicardial pacing is that it avoids contact with blood and intracardiac structures and thereby avoids uncommon but potentially devastating complications associated with endocardial pacemaker implantation. Read More

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December 2018
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Commentary Regarding "Outcomes After One Stage Versus Two Stage Open Repair of Type II Thoraco-abdominal Aortic Aneurysms".

Eur J Vasc Endovasc Surg 2018 Dec 11. Epub 2018 Dec 11.

German Aortic Centre Hamburg, Department of Vascular Medicine, University Heart Centre, Hamburg, Germany. Electronic address:

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December 2018

Second-line treatment efficacy and toxicity in older vs. non-older patients with advanced gastric cancer: A multicentre real-world study.

J Geriatr Oncol 2018 Dec 11. Epub 2018 Dec 11.

Department of Oncology, University and General Hospital, Udine, Italy; Department of Oncology, San Bortolo General Hospital, ULSS8 Berica - East District, Vicenza, Italy. Electronic address:

Objectives: Although gastric cancer (GC) incidence rises with age, older patients are poorly represented in clinical trials, whose results are therefore difficult to translate into standard management of older patients. Purpose of this study was to compare clinico-pathological features and survival outcomes between older and non-older patients with advanced GC treated with at least two chemotherapy lines.

Materials And Methods: Clinico-pathological characteristics, basal values, and treatment data of older (≥70 years at second-line start) and non-older patients were compared using chi-square test or 2-tailed Fisher exact test. Read More

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December 2018

Penile Prosthesis Reservoir Removal: Surgical Description and Patient Outcomes.

J Sex Med 2018 Dec 11. Epub 2018 Dec 11.

Division of Urology, Rutgers New Jersey Medical School, East Orange, NJ, USA. Electronic address:

Background: Removal of the penile prosthesis reservoir can be technically challenging because of its difficult locations either deep in the pelvis or high in the abdominal wall.

Aim: To describe a detailed surgical technique for reservoir removal through a penoscrotal approach.

Methods: We describe our preferred method for removal of prosthetic reservoir and present a retrospective review of patient outcomes after reservoir removal. Read More

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December 2018
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Insect heart rhythmicity is modulated by evolutionarily conserved neuropeptides and neurotransmitters.

Curr Opin Insect Sci 2018 Oct 11;29:41-48. Epub 2018 Jun 11.

Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA. Electronic address:

Insects utilize an open circulatory system to transport nutrients, waste, hormones and immune factors throughout the hemocoel. The primary organ that drives hemolymph circulation is the dorsal vessel, which is a muscular tube that traverses the length of the body and is divided into an aorta in the head and thorax, and a heart in the abdomen. The dorsal vessel is myogenic, but its rhythmicity is modulated by neuropeptides and neurotransmitters. Read More

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October 2018

DA-9701 (Motilitone): A Multi-Targeting Botanical Drug for the Treatment of Functional Dyspepsia.

Authors:
Mirim Jin Miwon Son

Int J Mol Sci 2018 Dec 13;19(12). Epub 2018 Dec 13.

Research Center & Phytotherapeutics Group, Viromed, Co. Ltd., Seoul 08826, Korea.

Functional dyspepsia (FD) is the most common functional gastrointestinal disorder (FGID). FD is characterized by bothersome symptoms such as postprandial fullness, early satiety, and epigastric pain or burning sensations in the upper abdomen. The complexity and heterogeneity of FD pathophysiology, which involves multiple mechanisms, make both treatment and new drug development for FD difficult. Read More

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December 2018

Gender- and Age-Related Changes in Trunk Muscle Composition Using Chemical Shift Encoding-Based Water⁻Fat MRI.

Nutrients 2018 Dec 13;10(12). Epub 2018 Dec 13.

Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.

Ageing, sarcopenia, and malnutrition are associated with quantitative and qualitative changes of body composition. There are several imaging modalities, including magnetic resonance imaging (MRI), for the assessment of trunk muscle tissue composition. In this study, we investigated the gender- and age-related changes in trunk muscle composition using chemical shift encoding-based water⁻fat MRI. Read More

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December 2018

Nox1/4 dual inhibitor GKT137831 attenuates hypertensive cardiac remodelling associating with the inhibition of ADAM17-dependent proinflammatory cytokines-induced signalling pathways in the rats with abdominal artery constriction.

Biomed Pharmacother 2019 Jan 26;109:1907-1914. Epub 2018 Nov 26.

Department of Pharmacy, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Electronic address:

NADPH oxidases (Noxs) 1/4 dual inhibitor GKT137831 prevents hypertensive cardiac remodelling in angiotensin II-infused transgenic mice with cardiomyocyte-specific human Nox4 (c-hNo x 4 Tg); however, further research is still required to determine the beneficial role of GKT137831 in hypertensive cardiac remodelling in other types of hypertensive models because this hypertensive model is insufficient to mimic the complicated pathological mechanisms of hypertension. A disintegrin and metalloprotease 17 (ADAM17) promotes the shedding of tumour necrosis factor α (TNF-α), TNF-α receptor, interleukin 1 receptor-II and interleukin 6 (IL-6) receptor from cells, thereby mediating the signalling pathways induced by corresponding proinflammatory cytokines. This study aimed to determine whether GKT137831 prevents hypertensive cardiac remodelling and its mechanisms of action in the rats with abdominal artery coarctation (AAC). Read More

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January 2019

Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential.

Biomed Pharmacother 2019 Jan 13;109:1428-1436. Epub 2018 Nov 13.

Medical Research and Education Center, Lomonosov Moscow State University, Moscow, Russian Federation; Faculty of Medicine, Lomonosov Moscow State University, Moscow, Russian Federation. Electronic address:

Male infertility represents a severe social and medical challenge. In recent years the progress in regenerative medicine promoted the development of novel options to overcome this medical condition. We are elaborating a promising approach to restore spermatogenesis using mesenchymal stromal cell (MSC) secretome components as a novel class of cell-free cell therapy medicinal products for regenerative medicine. Read More

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January 2019

Comparison of effects of MHBFC on cardiac hypertrophy after banding of the abdominal aorta in wild-type mice and eNOS knockout mice.

Biomed Pharmacother 2019 Jan 7;109:1221-1232. Epub 2018 Nov 7.

Pharmaceutical College, Guangxi Medical University, Nanning, 530021, Guangxi, PR China. Electronic address:

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January 2019

FTY720 inhibits the activation of pancreatic stellate cells by promoting apoptosis and suppressing autophagy via the AMPK/mTOR pathway.

Life Sci 2018 Dec 11. Epub 2018 Dec 11.

Department of Cell and Molecular Biology, Institute of Acute Abdominal Diseases of Integrated Traditional Chinese and Western Medicine, Tianjin Nankai Hospital, Tianjin 300100, China; Nankai Clinical College, Tianjin Medical University, Tianjin 300107, China. Electronic address:

Aims: Pancreatic stellate cells (PSCs) play a critical role in the development of pancreatic fibrosis. Any agents that can affect PSC activation could become potential candidates for treating pancreatic fibrosis. FTY720 can attenuate chronic pancreatic fibrosis by suppressing T-cell infiltration, but its effect on PSCs remains unknown. Read More

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December 2018
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A technique to rapidly generate synthetic CT for MRI-guided online adaptive re-planning: an exploratory study.

Int J Radiat Oncol Biol Phys 2018 Dec 11. Epub 2018 Dec 11.

Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI.

Purpose/objective(s): To develop an automatic and accurate atlas based technique for synthetic CT (sCT) generation to be used for online adaptive replanning during MRI guided radiation therapy (RT).

Materials/methods: The proposed method utilizes deformable image registration (DIR) of daily MRI and reference CT with additional corrections to maintain bone rigidity and also transfer of random air regions by thresholding. The DIR is performed with constraints on the bony structures using a special algorithm of ADMIRE (Elekta). Read More

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December 2018
3 Reads

Laparoscopic versus open appendectomy for complicated appendicitis.

Medwave 2018 Dec 11;18(8):e7370. Epub 2018 Dec 11.

Proyecto Epistemonikos, Santiago, Chile; Centro Evidencia UC, Pontificia Universidad Católica de Chile, Santiago, Chile; Departamento de Medicina Interna, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Email: Address: Centro Evidencia UC, Pontificia Universidad Católica de Chile, Diagonal Paraguay 476, Santiago, Chile.

Introduction: The treatment of acute appendicitis using laparoscopy reduces the risk of wound infection, hospitalization time and return to normal activity. However, it increases the risk of intra-abdominal abscess, which is one the main complications of complicated appendicitis.

Methods: We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. Read More

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December 2018
1 Read

Differential role of natural killer group 2D in recognition and cytotoxicity of hepatocyte-like cells derived from embryonic stem cells and induced pluripotent stem cells.

Am J Transplant 2018 Dec 14. Epub 2018 Dec 14.

Stanford Immunology, Stanford University School of Medicine, Stanford, CA, USA.

Stem cell-based approaches have the potential to address the organ shortage in transplantation. Whereas both embryonic stem cells and induced pluripotent stem cells have been utilized as cellular sources for differentiation and lineage specification, their relative ability to be recognized by immune effector cells is unclear. We determined the expression of immune recognition molecules on hepatocyte-like cells (HLC) generated from murine embryonic stem cells and induced pluripotent stem cells, compared to adult hepatocytes, and we evaluated the impact on recognition by NK cells. Read More

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December 2018

Intraductal papillary neoplasm of the bile duct (IPNB): a rare precursor of cholangiocarcinoma.

Liver Int 2018 Dec 14. Epub 2018 Dec 14.

Department of Pathology, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.

Laboratory tests in an asymptomatic 70-year-old Caucasian man revealed biological cholestasis with an increased level of γ-GT. Abdominal tomography showed a mass in the left hepatic lobe, nearly four centimeters in diameter and associated with a dilated left bile duct. PET imaging revealed high glucose uptake. Read More

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December 2018
1 Read

Ultrasound Assessment of Hepatobiliary and Splenic Changes in Patients With Dengue and Warning Signs During the Acute and Recovery Phases.

J Ultrasound Med 2018 Dec 14. Epub 2018 Dec 14.

Infectious Diseases, Federal University of Triângulo Mineiro, Uberaba, Brazil.

Objectives: To evaluate whether abdominal ultrasound (US) with a gallbladder (GB) contractility study or motor function test can be used as a diagnostic tool in patients with dengue and warning signs in acute and recovery phases.

Methods: Fifty-one individuals in the acute phase of dengue presenting with warning signs (dengue group) and 49 healthy individuals without a history of dengue or hepatobiliary disease (control group) were studied with abdominal US and a GB contractility study.

Results: Statistical differences in US measurements of the liver (right lobe, P = . Read More

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December 2018

Induction of fat apoptosis by a non-thermal device: Mechanism of action of non-invasive high-intensity electromagnetic technology in a porcine model.

Lasers Surg Med 2018 Dec 14. Epub 2018 Dec 14.

Veterinary Research Institute, Brno, Czech Republic.

Objectives: While controlled thermal changes in subcutaneous tissue have been used to trigger apoptosis of fat cells and have been proven clinically efficacious, another mechanism of electromagnetic stress suggests that fat apoptosis could be achieved by a non-thermal manner as well. This animal model study investigates the use of a non-invasive high-intensity magnetic field device to induce apoptosis in fat cells.

Methods: Yorkshire pigs (N = 2) received one treatment (30 minutes) in the abdominal area using a High-Intensity Focused Electromagnetic (HIFEM) device. Read More

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December 2018
1 Read

Waist circumference and abdominal volume index are the strongest anthropometric discriminators of metabolic syndrome in Spanish adolescents.

Eur J Clin Invest 2018 Dec 14:e13060. Epub 2018 Dec 14.

Department of Nursing, University of Granada, Av. Ilustración, 60, 18016, Granada, Spain.

Background: Waist circumference has been suggested as predictor for metabolic syndrome (MetS) in adolescents but it has not been compared with newly proposed anthropometric indexes. This study aimed to disclose the capacity of ten classic and novel anthropometric indexes to discriminate by the presence of MetS in this young population.

Materials And Methods: A cross-sectional study was performed on 981 adolescents (13. Read More

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December 2018

Laparoscopic reversal of Hartmann's procedure: A single-center experience.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Morphology, Experimental Medicine and Surgery, Section of General and Thoracic Surgery, University of Ferrara, Ferrara, Italy.

Introduction: Laparoscopic reversal of Hartmann's procedure (LHR) is considered a technically complex major surgical procedure. We present a retrospective analysis of a single-institution experience that assesses the treatment patterns and outcomes of patients who underwent LHR.

Materials And Surgical Technique: The study involved patients who underwent LHR between January 2004 and December 2017. Read More

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December 2018

Safe and easy technique for the laparoscopic application of Seprafilm® in gynecologic surgery.

Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Obstetrics and Gynecology, School of Medicine, Keio University, Tokyo, Japan.

Introduction: Laparoscopic surgery is a minimally invasive surgery, and the rate of postoperative adhesions is low. Although Seprafilm® helps to reduce adhesions, its application in the abdominal cavity during laparoscopic surgery is difficult because of its material. Therefore, we propose an easy method for applying this adhesion barrier. Read More

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December 2018

Splenic marginal zone lymphoma leads to sinistral portal hypertension.

J Dig Dis 2018 Dec 14. Epub 2018 Dec 14.

Department of Gastroenterology, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.

Sinistral portal hypertension (SPH), also known as left-sided portal hypertension, accounts for 5% of all portal hypertension (PH) cases. SPH is commonly secondary to acute or chronic pancreatitis and pancreatic cancer and rarely secondary to peritoneal inflammatory disease, abdominal tumors or diseases of the spleen . Splenic marginal zone lymphoma (SMZL) is a rare type of non-Hodgkin's lymphoma that originates from the lymphocytes of the splenic white pulp. Read More

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December 2018
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Multiple psychological factors predict abdominal pain severity in children with irritable bowel syndrome.

Neurogastroenterol Motil 2018 Dec 13:e13509. Epub 2018 Dec 13.

Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

Background: Anxiety and depression are implicated as contributors to abdominal pain in pediatric irritable bowel syndrome (IBS) but is unclear if this pain is associated with other psychological factors. The study objective was to test if the impact of anxiety or depression on IBS symptom severity is mediated by somatization and/or pain catastrophizing.

Methods: We utilized baseline data from local pediatric IBS clinical studies. Read More

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December 2018

Voiding behavior and chronic pelvic pain in two types of rat nonbacterial prostatitis models: Attenuation of chronic pelvic pain by repeated administration of tadalafil.

Prostate 2018 Dec 14. Epub 2018 Dec 14.

Research Laboratories, Nippon Shinyaku Co., Ltd., Minami-ku, Kyoto, Japan.

Background: Experimental autoimmune prostatitis (EAP) and prostatitis induced by 17β-estradiol treatment combined with castration (hormone/castration-induced prostatitis; HCP) are the most commonly used rodent models of nonbacterial prostatitis. We studied the effect of the phosphodiesterase 5 inhibitor tadalafil on chronic pelvic pain in two such models in rats.

Methods: EAP was induced by intradermal injection of rat prostate antigen and complete Freund's adjuvant on Days 0 and 28. Read More

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December 2018

Veterinary-focused assessment with sonography for trauma-airway, breathing, circulation, disability and exposure: a prospective observational study in 64 canine trauma patients.

J Small Anim Pract 2018 Dec 13. Epub 2018 Dec 13.

Lodi's ICU and Sub ICU Head, ASST Lodi 26900, Italy.

Objective: To describe the technique and findings of the 'veterinary focused assessment with sonography for trauma-airway, breathing, circulation, disability and exposure' protocol in dogs suffering from trauma.

Materials And Methods: Prospective observational study on a new point-of-care ultrasound protocol on 64 dogs suffering from trauma and comparison of findings with radiology.

Results: Comparison of the results of this new ultrasound protocol for trauma patients with radiography findings for pneumothorax, pleural effusion, alveolar-interstitial syndrome and abdominal effusion revealed positive agreement of 89, 83, 100 and 87% and negative agreement of 76, 83, 76 and 92%, respectively. Read More

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December 2018
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Motor Neuroprostheses.

Authors:
Arthur Prochazka

Compr Physiol 2018 Dec 13;9(1):127-148. Epub 2018 Dec 13.

Neuroscience and Mental Health Institute (NMHI), School of Molecular & Systems Medicine, University of Alberta, Edmonton, Alberta, Canada.

Neuroprostheses (NPs) are electrical stimulators that activate nerves, either to provide sensory input to the central nervous system (sensory NPs), or to activate muscles (motor NPs: MNPs). The first MNPs were belts with inbuilt batteries and electrodes developed in the 1850s to exercise the abdominal muscles. They became enormously popular among the general public, but as a result of exaggerated therapeutic claims they were soon discredited by the medical community. Read More

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December 2018
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