5,313 results match your criteria ASAIO journal American Society for Artificial Internal Organs : 1992[Journal]


Pulsatile Conduit Pressure Gradients in the HeartWare HVAD.

ASAIO J 2019 Feb 11. Epub 2019 Feb 11.

From the St Vincent's Hospital, Sydney, New South Wales, Australia.

We evaluated mean, peak, and instantaneous pressure gradients across the outflow conduit in a pulsatile mock circulation loop which incorporated Heartware HVADs for left ventricular (LV) and right ventricular (RV) support. Steady-state 50 Hz measurements of left ventricular assist device (LVAD) flow (Q) and pressures within the proximal and distal outflow conduit were obtained at varying pump speed, LV contractility, hematocrit (HCT), heart rate (HR), and conduit diameter and length. Experiments were conducted using polyvinyl chloride (PVC) tubing and results confirmed in HVAD Gelweave conduit. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000964DOI Listing
February 2019

Extracorporeal Membrane Oxygenation for Massive Pulmonary Embolism as Bridge to Therapy.

ASAIO J 2019 Jan 29. Epub 2019 Jan 29.

From the Department of Cardiothoracic Surgery.

Pulmonary Embolism (PE) is a common illness in western countries. The purpose of this study is to report the institutional experience with massive PE and Extracorporeal Membrane Oxygenation (ECMO) in inoperable patients on admission. A retrospective analysis using the institutional ECMO-registry including the time between 2006 and 2017 was performed. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000953DOI Listing
January 2019
2 Reads

Meet the Authors.

Authors:

ASAIO J 2019 Feb;65(2):122

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http://dx.doi.org/10.1097/01.mat.0000553514.68048.7cDOI Listing
February 2019

Impact and Measurement of Blood Pressure During Continuous Flow Left Ventricular Assist Device Support: The Pressure Is On!

ASAIO J 2019 Feb;65(2):101-103

From the Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

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http://dx.doi.org/10.1097/MAT.0000000000000960DOI Listing
February 2019

Increased Stroke Risk in Children and Young Adults on Extracorporeal Life Support with Carotid Cannulation.

ASAIO J 2019 Jan 24. Epub 2019 Jan 24.

Division of Cardiac Surgery, Seattle Children's Hospital, Seattle, Washington.

Patients on extracorporeal life support (ECLS) are at risk for central nervous system (CNS) injury. One potentially modifiable risk factor is site of arterial cannulation in venoarterial (VA) ECLS, as in most cases one can choose the femoral or carotid artery. There is acute alteration in cerebral blood flow with carotid cannulation, potentially increasing the risk of stroke. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000912DOI Listing
January 2019

Risk Assessment in Patients with a Left Ventricular Assist Device Across INTERMACS Profiles Using Bayesian Analysis.

ASAIO J 2019 Jan 24. Epub 2019 Jan 24.

School of Biomedical Engineering, Cornell University, New York.

Current risk stratification models to predict outcomes after a left ventricular assist device (LVAD) are limited in scope. We assessed the performance of Bayesian models to stratify post-LVAD mortality across various International Registry for Mechanically Assisted Circulatory Support (INTERMACS or IM) Profiles, device types, and implant strategies. We performed a retrospective analysis of 10,206 LVAD patients recorded in the IM registry from 2012 to 2016. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000910DOI Listing
January 2019

Dual-Propeller Cavopulmonary Pump for Assisting Patients with Hypoplastic Right Ventricle.

ASAIO J 2019 Jan 24. Epub 2019 Jan 24.

Department of Radiology, MedStar Medical Group Radiology, Baltimore, Maryland.

Various congenital heart defects (CHDs) are characterized by the existence of a single functional ventricle, which perfuses both the systemic and pulmonary circulation. A three-stage palliation procedure, including the final Fontan completion, is often adopted by surgeons to treat patients with such CHDs. The completion Fontan involves the creation of a total cavopulmonary connection (TCPC), commonly accomplished with an extracardiac conduit. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000907DOI Listing
January 2019
4 Reads

Experimental Study of the Tissue Repair of Neo-Esophagus After Esophageal Muscularis Resection.

ASAIO J 2019 Jan 24. Epub 2019 Jan 24.

Department of Surgery, High-ranking Medical Service Center, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Attempts have been made to observe the tissue repair of neo-esophagus after esophageal muscularis resection and to investigate possibility of the regeneration repair of esophageal muscularis resection in neo-esophagus. Sixteen pigs were divided into two groups: group A and group B. Pigs in group A were performed with the partial resection of mere esophageal muscularis propria reserved mucosa muscle layer in a segment of thoracic esophagus. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000951DOI Listing
January 2019

Detection of Thromboembolic Events and Pump Thrombosis in HeartWare HVAD Using Accelerometer in a Porcine Model.

ASAIO J 2019 Jan 24. Epub 2019 Jan 24.

From the Intervention Centre, Oslo University Hospital, Oslo, Norway.

We have recently demonstrated that accelerometer-based pump thrombosis and thromboembolic events detection is feasible in vitro. This article focuses on detection of these conditions in vivo. In an open-chest porcine model (n = 7), an accelerometer was attached to the pump casing of an implanted HeartWare HVAD. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000954DOI Listing
January 2019

Effect of Heart Rate Reserve on Exercise Capacity in Patients Treated with a Continuous Left Ventricular Assist Device.

ASAIO J 2019 Jan 24. Epub 2019 Jan 24.

From the Department of Cardiology, Rigshospitalet, Copenhagen, Denmark.

We hypothesized that an inadequate increase in heart rate (HR) during exercise was associated with low peak oxygen uptake (VO2 peak) seen in left ventricular assist device (LVAD) recipients and aimed to analyze the potential relation between HR and VO2 peak and use of drugs with negative chronotropic effect. Sixty-eight LVAD recipients (44 Heartmate 2 and 24 HVAD) with support duration >1 month and a VO2 peak were included from two centers. Patients were 57 ± 13 years at time of VO2 peak and LVAD support duration was 483 ± 545 days. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000955DOI Listing
January 2019

Clinical Courses of HeartMate II Left Ventricular Assist Device Thrombosis.

ASAIO J 2019 Jan 24. Epub 2019 Jan 24.

From the Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.

We observed different temporal patterns of HeartMate II left ventricular assist device (LVAD) thrombosis regarding clinical manifestations and lactate dehydrogenase (LDH) trends. We propose nomenclature for classification of LVAD thrombosis and compare patient characteristics and outcomes in each pattern of LVAD thrombosis. We reviewed electronic medical records of 362 consecutive HeartMate II devices implanted at Cleveland Clinic from October 2008 to July 2014. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000952DOI Listing
January 2019
3 Reads

The Physiology of Percutaneous Right Ventricular Assist Device-Potential Effects on Ventilation-Perfusion Matching.

ASAIO J 2019 Jan 14. Epub 2019 Jan 14.

From the University Hospital Birmingham NHS Foundation Trust, Birmingham, United Kingdom.

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http://dx.doi.org/10.1097/MAT.0000000000000944DOI Listing
January 2019

Neurologic Outcomes in a Two-Center Cohort of Neonatal and Pediatric Patients Supported on Extracorporeal Membrane Oxygenation.

ASAIO J 2019 Jan 14. Epub 2019 Jan 14.

Kennedy Krieger Institute, Baltimore, Maryland.

Contemporary studies of long-term outcomes in children supported on extracorporeal membrane oxygenation (ECMO) in the United States are limited. We enrolled 99 ECMO patients between July 2010 and June 2015 in a two-center prospective observational study that included neurologic and neuropsychologic evaluation at 6 and 12 months, using standardized outcome measures. Pre-ECMO, 20 (20%) had a pre-existing neurologic diagnosis, 40 (40%) had cardiac arrest, and 10 of 47 (21%) children with neuroimaging had acute abnormal findings. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000933DOI Listing
January 2019

Chronic Ovine Studies Demonstrate Low Thromboembolic Risk in the Penn State Infant Ventricular Assist Device.

ASAIO J 2019 Jan 14. Epub 2019 Jan 14.

From the Department of Surgery, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine, Penn State Children's Hospital, Hershey, Pennsylvania.

Mechanical circulatory support for children under 6 years of age remains a challenge. This article describes the preclinical status and the results of recent animal testing with the Penn State Infant Left Ventricular Assist Device (VAD). The objectives have been to 1) demonstrate acceptably low thromboembolic risk to support FDA approval, 2) challenge the device by using minimal to no anticoagulation in order to identify any design or manufacturing weaknesses, and 3) improve our understanding of device thrombogenicity in the ovine animal model, using multicomponent measurements of the coagulation system and renal ischemia quantification, in order to better correlate animal results with human results. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000945DOI Listing
January 2019

Understanding Urea Kinetic Factors That Enhance Personalized Hemodialysis Prescription in Children.

ASAIO J 2019 Jan 14. Epub 2019 Jan 14.

From the Pediatric Pharmacology & Pharmacometrics, University of Basel Children's Hospital, Basel, Switzerland.

Urea dialyzer clearance (KD) has been suggested to be underpredicted from blood flow (QB), dialysate flow (QD), and in vitro mass transfer-area coefficient of urea (KoA) in pediatric hemodialysis (HD) patients using a widely accepted mechanistic equation. We characterize factors that could explain this, assuming that it results from a bias between reported in vitro and actual in vivo KoA. An adult urea kinetic model was scaled to 923 patients aged 1-29 years based on pediatric physiologic knowledge (intercompartmental clearance, volumes of distribution). Read More

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http://dx.doi.org/10.1097/MAT.0000000000000941DOI Listing
January 2019

Acute Pump Thrombosis in the Early Postoperative Period After HeartMate 3 Implantation.

ASAIO J 2019 Jan 14. Epub 2019 Jan 14.

From the Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands.

There are no reports of acute pump thrombosis in the latest, continuous flow left ventricular assist devices type HeartMate 3, other than thrombus ingestion. We present a case of early thrombosis of the pump and outflow graft, necessitating acute pump and outflow graft replacement. A combination of low-flow episodes and subtherapeutic levels of anticoagulation was the most likely cause. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000932DOI Listing
January 2019

Improving Outcomes in INTERMACS 1 Category 1 Patients with Pre-LVAD, Awake Venous-Arterial Extracorporeal Membrane Oxygenation Support.

ASAIO J 2019 Jan 24. Epub 2019 Jan 24.

From the Section of Cardiac Surgery, Yale School of Medicine, New Haven, Connecticut.

Effective strategies to optimize Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS 1) patients are in much need. A novel awake venous-arterial extracorporeal membrane oxygenation (aVA ECMO) allows for clinical assessments while temporarily supporting biventricular function and stabilizing end-organ functions. The aim of the study was to assess outcomes of patients with aVA ECMO support before durable left ventricular assist device (LVAD) implantation. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000908DOI Listing
January 2019
5 Reads

Monitoring Platelet Function in Children With Ventricular Assist Devices: The Devil Is in the Details.

ASAIO J 2019 Feb;65(2):104-105

Blood Research Institute, Versiti, Medical College of Wisconsin, Milwaukee, Wisconsin.

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http://dx.doi.org/10.1097/MAT.0000000000000948DOI Listing
February 2019
1 Read

Does Tolvaptan Have Any Therapeutic Roles in Patients With Left Ventricular Assist Device?

Authors:
Teruhiko Imamura

ASAIO J 2019 Jan 9. Epub 2019 Jan 9.

Division of Cardiology, University of Chicago Medical Center, Chicago, Illinois,

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http://dx.doi.org/10.1097/MAT.0000000000000949DOI Listing
January 2019
1 Read

Yes or No. Tolvaptan May Be a Potential Alternative to Loop Diuretics in Patients With Left Ventricular Assist Device.

ASAIO J 2019 Jan 9. Epub 2019 Jan 9.

Department of Pharmacy Practice, South Dakota State University, Sioux Falls, South Dakota, Department of Pharmacy, Avera McKennan Hospital, Sioux Falls, South Dakota Gill Heart Institute, University of Kentucky HealthCare, Lexington, Kentucky.

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http://dx.doi.org/10.1097/MAT.0000000000000950DOI Listing
January 2019
1 Read

Lupus and Left Ventricular Assist Devices: High-Risk for Bleeding?

ASAIO J 2019 Jan 9. Epub 2019 Jan 9.

Section of Heart Failure, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio.

Continuous-flow left ventricular assist devices (LVAD) have become an increasingly utilized treatment strategy for patients with end-stage heart failure. Despite the improved outcomes evident with current generation pumps, proper patient selection remains crucial to minimize the risk of potential adverse events. The evolving use of these devices as destination therapy (DT) has led to growing numbers of patients with higher risk comorbid conditions being evaluated as potential LVAD candidates. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000946DOI Listing
January 2019
2 Reads

Extracorporeal Carbon Dioxide Removal in the Management of Complex Bilateral Flail Chest Injury.

ASAIO J 2019 Jan 3. Epub 2019 Jan 3.

From the Division of Critical Care Medicine, Department of Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana.

Flail chest is an uncommon consequence of traumatic injury. Medical management includes mechanical ventilation for internal pneumatic stabilization. Control of respiratory drive is necessary to avoid paradoxical movement and impairment of recovery. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000942DOI Listing
January 2019
3 Reads
1.385 Impact Factor

Update on Extracorporeal Membrane Oxygenation Coding.

ASAIO J 2019 Jan 3. Epub 2019 Jan 3.

From the Division of Acute Care Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/MAT.0000000000000940DOI Listing
January 2019
1 Read

Semiquantification of Systemic Venous Admixture During Venovenous Extracorporeal Oxygenation Via Bicaval Double-Lumen Cannula in Critically Ill Patients.

ASAIO J 2018 Dec 28. Epub 2018 Dec 28.

Department of Cardiothoracic Surgery, St George Hospital, Kogarah, New South Wales, Australia.

Venovenous extracorporeal membrane oxygenation (VV-ECMO) is increasingly utilized in acute reversible cases of severe respiratory failure and as a bridge to lung transplantation. Venovenous extracorporeal membrane oxygenation using a bicaval double-lumen cannula (BCDLC) has several advantages over the traditional ECMO configuration; however, it also presents with several unique challenges. The assessment and quantification of venous admixture is difficult due to the specific position of BCDLC within the circulatory system. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000943DOI Listing
December 2018
1 Read

An Artificial Placenta Protects Against Lung Injury and Promotes Continued Lung Development in Extremely Premature Lambs.

ASAIO J 2018 Dec 18. Epub 2018 Dec 18.

From the Extracorporeal Life Support Laboratory, Department of Surgery, Michigan Medicine, Ann Arbor, Michigan.

An artificial placenta (AP) utilizing extracorporeal life support (ECLS) could protect premature lungs from injury and promote continued development. Preterm lambs at estimated gestational age (EGA) 114-128 days (term = 145) were delivered by Caesarian section and managed in one of three groups: AP, mechanical ventilation (MV), or tissue control (TC). Artificial placenta lambs (114 days EGA, n = 3; 121 days, n = 5) underwent venovenous (VV)-ECLS with jugular drainage and umbilical vein reinfusion for 7 days, with a fluid-filled, occluded airway. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000939DOI Listing
December 2018
1 Read

LVAD Outflow Graft Role in Pump Thrombosis.

ASAIO J 2018 Dec 18. Epub 2018 Dec 18.

From the Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, North Carolina.

Left ventricular assist devices are (LVAD) used for circulatory support in patients with end-stage heart failure. Hemolysis/pump dysfunction is a well-known complication of this therapy with various etiologic causes. A small proportion of these complications are caused by outflow graft obstructions; this complication has received little attention in the scientific literature. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000936DOI Listing
December 2018
1 Read

Management of Antiplatelet Therapy During Continuous-Flow Left Ventricular Assist Device Support After Thrombotic Hemorrhagic Events.

ASAIO J 2018 Dec 18. Epub 2018 Dec 18.

From the Department of Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine, Louisville, Kentucky.

Hemorrhagic or thrombotic events are common complications in heart failure patients with continuous-flow left ventricular assist device (CF-LVAD) support. Aim of this study is to investigate the effect of change in antiplatelet therapy after thrombotic or hemorrhagic events in patients with CF-LVAD support. A total of 231 CF-LVAD patients were included in this study. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000935DOI Listing
December 2018
5 Reads

Inflammatory Effects of Blood-Air Interface in a Porcine Cardiopulmonary Bypass Model.

ASAIO J 2018 Dec 18. Epub 2018 Dec 18.

Department of Cardiac Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.

Cardiopulmonary bypass (CPB) causes a systemic inflammatory response syndrome (SIRS) associated with multiorgan injury. A model was developed to test whether a blood-air interface (BAI) in the CPB circuit causes blood element activation and inflammation. Ten healthy swine were placed on partial CPB for 2 hours via the cervical vessels and monitored for 96 hours postoperatively. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000938DOI Listing
December 2018
1 Read

The Impact of Left Ventricular Assist Device Infections on Postcardiac Transplant Outcomes: A Systematic Review and Meta-Analysis.

ASAIO J 2019 Jan 4. Epub 2019 Jan 4.

Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada.

Left ventricular assist devices (LVADs) are associated with numerous short- and long-term complications, including infection. The impact LVAD infections have on clinical outcomes after transplantation is not well established. We sought to determine whether the presence of infection while on LVAD support negatively influences outcomes after cardiac transplantation. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000921DOI Listing
January 2019
1 Read

Benefits of Impella and Peripheral Veno-Arterial Extra Corporeal Life Support Alliance.

ASAIO J 2018 Dec 11. Epub 2018 Dec 11.

From the Cardio-thoracic Surgery Department.

Peripheral veno-arterial extra corporeal life support (V-A ECLS) is an effective tool in treating refractory cardiogenic shock (RCS). Despite additional use of intra-aortic balloon pump, insufficient left ventricular unloading is a likely complication. We present herein our experience combining V-A ECLS and Impella to treat symptomatic, critical patients. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000922DOI Listing
December 2018
19 Reads

Dopamine Optimizes Venous Return During Cardiopulmonary Bypass and Reduces the Need for Postoperative Blood Transfusion.

ASAIO J 2018 Dec 14. Epub 2018 Dec 14.

From the GVM Care & Research, Department of Cardiovascular Surgery, Anthea Hospital, Bari, Italy.

Venodilation occurs shortly after the institution of cardiopulmonary bypass (CPB), necessitating fluid or vasoconstrictor administration to maintain adequate oxygen delivery. The vasoconstrictor effects of dopamine are not well studied in this context. Therefore, we conducted a single-center, double-blind case-control study to determine the role and utility of dopamine as a vasoconstrictor during CPB. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000930DOI Listing
December 2018
11 Reads
1.385 Impact Factor

Left Ventricular Assist Device Outflow Graft Obstruction: A Complication Specific to Polytetrafluoroethylene Covering. A Word of Caution!

ASAIO J 2018 Dec 10. Epub 2018 Dec 10.

Department of Surgery, Division of Transplantation, University of Kentucky, Lexington, Kentucky.

Pump thrombosis is an established complication of left ventricular assist devices (LVADs). Outflow graft obstruction has been previously described as one cause of LVAD thrombosis. We identified four cases of outflow graft obstruction that were attributed to a commonly applied polytetrafluoroethylene (PTFE) covering of the outflow graft. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000929DOI Listing
December 2018
2 Reads

A Comparative Content Analysis of Digital Channels for Ventricular Assist Device Patients, Caregivers, and Healthcare Practitioners.

ASAIO J 2018 Dec 10. Epub 2018 Dec 10.

Department of Mechanical and Aerospace Engineering, Monash University, Clayton, VIC, Australia.

This article seeks to review and analyze the emergence of digital channels designed for ventricular assist device (VAD) patients, caregivers, and practitioners and to understand how such digital channels support the user experience of VAD implantation. Following a content analysis methodology, the authors investigated 16 digital channels designed for VAD patients, caregivers, and practitioners, with data being analyzed thematically. Competitor Positioning Matrix diagrams were created to visually represent the landscape of digital channels that support VAD stakeholders. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000924DOI Listing
December 2018
1 Read

Interpreting Neurologic Outcomes in a Changing Trial Design Landscape: An Analysis of HVAD Using a Hybrid Intention to Treat Population.

ASAIO J 2018 Dec 7. Epub 2018 Dec 7.

Stanford University Medical Center, Stanford, California.

Randomized controlled trials can provide optimal clinical evidence to assess the benefits of new devices, and it is these data that often shape device usage in real-world practice. However, individual clinical trial results sometimes appear discordant for the same device, and alternative devices are sometimes not employed in similar patient populations. To make sound evidence-based decisions, clinicians routinely rely on cross-trial comparisons from different trials of similar but not identical patient populations to assess competing technology when head-to-head randomized comparisons are unavailable. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000931DOI Listing
December 2018
4 Reads

Indications and Outcomes for Temporary Mechanical Circulatory Support in Pediatric Patients with Cardiac Failure.

ASAIO J 2018 Dec 12. Epub 2018 Dec 12.

Duke University Hospital, Durham, North Carolina.

Temporary continuous-flow ventricular assist devices (cfVAD) and extracorporeal membrane oxygenation (ECMO) are options for temporary mechanical circulatory support in pediatric patients. Despite the increase in temporary cfVAD use, the literature describing its use in pediatrics is limited. This was a single-center retrospective review of temporary cfVAD and a cohort of similar ECMO patients between January 1, 2011, and June 30, 2016, in patients <19 years of age. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000819DOI Listing
December 2018
1 Read

ECMO Flow as a Sign of Intraabdominal Hemorrhage After Prolonged CPR.

ASAIO J 2018 Nov 28. Epub 2018 Nov 28.

From the Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.

Although life-saving, cardiopulmonary resuscitation (CPR) has been associated with traumatic injuries in adult patients surviving cardiac arrest. In addition to rib and sternal fractures, intraabdominal injuries have also been shown to occur, particularly after prolonged external cardiac massage. Early detection of these injuries remains difficult and is often masked by concomitant hemodynamic instability and the higher likelihood of other injuries such as retroperitoneal hemorrhage. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000927DOI Listing
November 2018
12 Reads

What Causes LVAD-Associated Ischemic Stroke? Surgery, Pump Thrombosis, Antithrombotics, and Infection.

ASAIO J 2019 Jan 3. Epub 2019 Jan 3.

Cerebrovascular Center of the Neurological Institute, Cleveland Clinic, Cleveland, Ohio.

Acute ischemic stroke (AIS) is a major complication in left ventricular assist device (LVAD) population. A better understanding of clinical risk factors associated with AIS may help mitigate risk of stroke. We reviewed prospectively collected data of 477 LVAD patients from a tertiary center from October 1, 2004 to December 31, 2016. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000901DOI Listing
January 2019
2 Reads

Outcomes of Repeat Left Ventricular Assist Device Exchange.

ASAIO J 2018 Nov 28. Epub 2018 Nov 28.

From the Division of Cardiothoracic Transplant and Assist Devices, Baylor College of Medicine.

Implantable continuous-flow left ventricular assist devices (CF-LVADs) are used for long-term LV support in bridging patients to heart transplantation or as destination therapy. With prolonged support times, some patients will have repeat complications necessitating multiple device exchanges. To elucidate the safety and efficacy of repeat device exchange, we retrospectively reviewed data from 25 patients who underwent two or more CF-LVAD implantations between July 2005 and August 2017. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000928DOI Listing
November 2018
2 Reads

Tau Is Elevated in Pediatric Patients on Extracorporeal Membrane Oxygenation.

ASAIO J 2018 Nov 28. Epub 2018 Nov 28.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas.

Neurologic injury is a known and feared complication of extracorporeal membrane oxygenation (ECMO). Neurologic biomarkers may have a role in assisting with early identification of such. Axonal biomarker tau has not been investigated in the pediatric ECMO population. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000923DOI Listing
November 2018
10 Reads

Use of Hemodynamic Ramp Study to Optimize Continuous-Flow Ventricular Assist Device in a Fontan Patient.

ASAIO J 2018 Nov 21. Epub 2018 Nov 21.

From the Division of Pediatric Cardiology, CS Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/MAT.0000000000000920DOI Listing
November 2018
1 Read

Acute In Vivo Evaluation of the Pittsburgh Pediatric Ambulatory Lung.

ASAIO J 2018 Nov 21. Epub 2018 Nov 21.

From the McGowan Institute for Regenerative Medicine, Pittsburgh, Pennsylvania.

Respiratory failure is a significant problem within the pediatric population. A means of respiratory support that readily allows ambulation could improve treatment. The Pittsburgh Pediatric Ambulatory Lung (P-PAL) is being developed as a wearable pediatric pump-lung for long-term respiratory support and has previously demonstrated positive benchtop results. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000918DOI Listing
November 2018
1 Read

Opening the "Dor," Not Always an Inferior Approach.

ASAIO J 2018 Nov 21. Epub 2018 Nov 21.

From the St. Vincent Hospital Indianapolis.

The Dor procedure was historically used to restore the geometry of the heart in a patient with a left ventricular (LV) aneurysm via reduction and reshaping of the LV with an aneurysmectomy. Unfortunately, morbidity and mortality remain high with this procedure, with many patients little to no recovery of their ejection fraction while developing severe diastolic failure, often requiring further support; however, the natural history of these patients remains largely unknown. Heart transplant has long been considered the most durable of treatment for patients with end-stage heart failure (HF), but because of the scarcity of donor hearts, the implantation of left ventricular assist devices (LVAD) for mechanical circulatory support has also proven to be an essential tool in the treatment of the advanced heart failure patient. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000919DOI Listing
November 2018
2 Reads

Left Ventricular Assist Device Decommissioning Compared with Explantation for Ventricular Recovery: A Systematic Review.

ASAIO J 2018 Nov 27. Epub 2018 Nov 27.

From the Division of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania.

Left ventricular assist device (LVAD) withdrawal with ventricular recovery represents the optimal outcome for patients previously implanted with an LVAD. The aim of this systematic review was to examine the patient outcomes of device withdrawal via minimally invasive pump decommissioning as compared with reoperation for pump explantation. An electronic search was performed to identify all studies in the English literature assessing LVAD withdrawal. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000926DOI Listing
November 2018
3 Reads
1.385 Impact Factor

Computed Tomography-Estimated Right Ventricular Function and Exercise Capacity in Patients with Continuous-Flow Left Ventricular Assist Devices.

ASAIO J 2018 Nov 27. Epub 2018 Nov 27.

From the Department of Cardiology.

Using four-dimensional (4D) cardiac computed tomography (CCT) scans at rest and immediately after exercise, we examined the right heart chamber sizes and systolic function and its association with exercise capacity in left ventricular assist device (LVAD) recipients. Fifteen patients with HeartMate (HM) II or 3 underwent echocardiography and maximal cardiopulmonary exercise test. Subsequently, contrast-enhanced CCT scans were performed at rest and immediately after two minutes of supine 25 Watt ergometer bike exercise. Read More

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November 2018
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Calcium Priming of the Central Venous Catheter Prevents a Drop in Ionized Calcium Concentration During Regional Citrate Anticoagulation.

ASAIO J 2018 Nov 7. Epub 2018 Nov 7.

Department of Anesthesia and Intensive Care, IRCCS Policlinico San Donato, San Donato Milanese, Italy.

During citrate-based Continuous Renal Replacement Therapy (CRRT), an infusion of calcium is necessary to replace the calcium lost in the effluent. The replacement takes place through a central venous catheter (CVC) that is primed with saline solution. Thus, we hypothesized a potential systemic anticoagulation because of unchelated citrate reaching the patient at the start of CRRT because of 0. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000911DOI Listing
November 2018
9 Reads

Extracorporeal Technologies Within the Social Media Labyrinth.

Authors:
Justyna Swol

ASAIO J 2018 Nov 7. Epub 2018 Nov 7.

Department of Respiratory Medicine, Allergology and Sleep Medicine, Paracelsus Medical University Nuremberg, General Hospital Nuremberg, Nuremberg, Germany.

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http://dx.doi.org/10.1097/MAT.0000000000000915DOI Listing
November 2018
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Obesity Is Associated with Driveline Infection of Left Ventricular Assist Devices.

ASAIO J 2018 Nov 5. Epub 2018 Nov 5.

From the Department of Advanced Cardiopulmonary Therapies and Transplantation, University of Texas-Houston McGovern Medical School and Memorial Hermann-Texas Medical Center, Houston, Texas.

In patients with left ventricular assist devices (LVADs), the association of driveline infection (DLI) and body mass index (BMI) remains controversial. The aim of this study was to explore a potential correlation between BMI and DLI in the LVAD patient population. A retrospective, single-center study evaluated patients who underwent LVAD implantation between May 2012 and July 2016. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000916DOI Listing
November 2018
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Large Dual-Lumen Extracorporeal Membrane Oxygenation Cannulas Are Associated with More Intracranial Hemorrhage.

ASAIO J 2018 Nov 5. Epub 2018 Nov 5.

Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland.

Large dual-lumen veno-venous (VV) extracorporeal membrane oxygenation (ECMO) cannulas may increase venous pressure in the brain, contributing to intracranial hemorrhage (ICH). A retrospective cohort study was performed using the extracorporeal life support organization (ELSO) registry. Propensity score matching was used to control for confounding. Read More

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http://dx.doi.org/10.1097/MAT.0000000000000917DOI Listing
November 2018
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Erratum.

Authors:

ASAIO J 2018 Nov/Dec;64(6):e195

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http://dx.doi.org/10.1097/01.mat.0000549495.89106.0aDOI Listing
November 2018
2 Reads