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Case Rep Otolaryngol 2022 14;2022:7232588. Epub 2022 May 14.

Department of Otolaryngology - Head and Neck Surgery, Washington University in Saint. Louis, School of Medicine, St Louis, MO 63110, USA.

Utilization of frontal balloon sinuplasty in pediatric complicated acute rhinosinusitis (ARS) is demonstrated to be a safe and expedient alternative to other procedures such as trephination or functional endoscopic sinus surgery (FESS) in this case series. We performed a retrospective review of six pediatric cases of frontal balloon sinuplasty for ARS with intracranial complications at a tertiary academic center. Patients underwent unilateral ( = 5) or bilateral dilation ( = 1) in addition to functional endoscopic sinus surgery (FESS) including anterior ethmoidectomy ( = 5) and maxillary antrostomy ( = 6). Read More

J Minim Invasive Surg 2021 Dec;24(4):175-179

Division of Foregut Surgery, Department of Surgery, Korea University College of Medicine, Seoul, Korea.

Foregut surgery largely involves benign diseases, and not only malignant diseases. However, for foregut surgeons in Asia, this fact has not been extensively utilized in their clinical practice due to the high burden of gastric cancer surgery. Although the prevalence of gastroesophageal reflux disease (GERD) in Eastern Asia, including Korea, is increasing, antireflux surgery (ARS) is still a fairly rare procedure in Korea. Read More

Front Med (Lausanne) 2022 6;9:893028. Epub 2022 May 6.

Dutch Medicines Evaluation Board (CBG-MEB), Utrecht, Netherlands.

With the implementation of the new EU regulation on diagnostics (IVDR) in May 2022, notified bodies will be required to assess Companion Diagnostics (CDx). The EMA and national medicines agencies will be consulted on the performance and safety of CDx. In this paper, we report on our systematic review on how the EMA has dealt with CDx in dossiers for marketing authorization procedures, in 2017-2019, and in scientific advice procedures in 2016-2020, prior to the implementation of the new IVDR. Read More

Front Med (Lausanne) 2022 6;9:871229. Epub 2022 May 6.

Geriatric Center and Department of Psychiatry and Psychotherapy, Tübingen University Hospital, Tübingen, Germany.

Introduction: Postoperative delirium (POD) is a common and serious adverse event of surgery in older people. Because of its great impact on patients' safety and quality of life, identification of modifiable risk factors could be useful. Although preoperative medication intake is assumed to be an important modifiable risk factor, the impact of anticholinergic drugs on the occurrence of POD seems underestimated in elective surgery. Read More

Int J MCH AIDS 2022 6;11(1):e522. Epub 2022 Mar 6.

Department of Pediatric Gastroenterology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 77030, USA.

Background And Objective: Therapeutic options for pediatric inflammatory bowel disease (PIBD) have dramatically changed over the last 20 years. However, the impact of modern medical management on PIBD outcomes remains unclear. We aimed to fill this gap in the literature by using a large, validated, national database, to study the change in hospitalization rates, surgical rates, and postoperative complications in PIBD over the last decade. Read More

Anim Nutr 2022 Sep 21;10:19-25. Epub 2022 Jan 21.

University of New England, Armidale, NSW, 2351, Australia.

An experiment was conducted to explore the effects of digestible amino acid (dAA) concentrations and supplemental protease on live performance and energy partitioning in broilers. Ross 308 male broilers ( = 288) were distributed into 24 floor pens and offered 1 of 4 dietary treatments with 6 replicates from 1 to 35 d of age. Dietary treatments consisted of a 2 × 2 factorial arrangement with dAA concentrations (standard and reduced [34 g/kg below standard]) and supplemental protease (without or with) as the main factors. Read More

Front Plant Sci 2022 4;13:891488. Epub 2022 May 4.

Department of Horticulture, University of Wisconsin-Madison, Madison, WI, United States.

Bud freezing survival strategies have in common the presence of an ice barrier that impedes the propagation of lethally damaging ice from the stem into the internal structures of buds. Despite ice barriers' essential role in buds freezing stress survival, the nature of ice barriers in woody plants is not well understood. High-definition thermal recordings of Ait. Read More

Front Plant Sci 2022 4;13:842597. Epub 2022 May 4.

Department of Biological Sciences, Mississippi State University, Starkville, MS, United States.

root cells developing into syncytia through the parasitic activities of the pathogenic nematode underwent isolation by laser microdissection (LM). Microarray analyses have identified the expression of a () homolog in syncytia undergoing parasitism but during a defense response. encodes part of the common symbiosis pathway (CSP) involving , and other CSP genes. Read More

Data Brief 2022 Jun 29;42:108223. Epub 2022 Apr 29.

Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5A, 02-106 Warsaw, Poland.

DNA replication in and other eukaryotes is performed mainly by polymerase epsilon (Pol ε) on the leading strand and polymerase delta (Pol δ) on the lagging strand. Using a mutant form of a DNA polymerase enables tracking its signature in the replicated DNA. Here, we used the allele encoding the catalytic subunit of Pol ε to analyse its contribution to DNA replication in yeast with the allele of an essential gene encoding a subunit of the GINS complex. Read More

Rom J Intern Med 2022 May 22. Epub 2022 May 22.

Division of Respiratory Medicine, University of Tsukuba, Mito Medical Center-Mito Kyodo General Hospital, Mito, Ibaraki, Japan.

A 59-year-old man who had smoked for 23 pack-years was admitted to our hospital because of two-month history of back pain. The chest computed tomography scan demonstrated combined pulmonary fibrosis and emphysema (CPFE) and an irregular shaped nodule in the left lower lobe of the lung. A biopsy obtained from samples from subcarinal lymph nodes revealed non-small cell lung cancer. Read More

Med Vet Entomol 2022 May 22. Epub 2022 May 22.

USDA-ARS, Center for Grain and Animal Health Research, Arthropod-Borne Animal Diseases Research Unit, Manhattan, Kansas, USA.

Adult house flies feed and breed in a variety of microbe-rich habitats and serve as vectors for human and animal pathogens. To better understand their role in harbouring and disseminating bacteria, we characterized the composition and diversity of bacterial communities in the gut of female house flies collected from three different habitats in Kansas: agricultural (dairy farm), urban (business area dumpsters) and mixed (business located between residential and animal agriculture areas). Bacterial community composition and diversity were influenced more by the house flies' habitat than by sampling time. Read More

Plant Biotechnol J 2022 May 22. Epub 2022 May 22.

Earlham Institute, Norwich, Norfolk, NR4 7UZ, UK.

Wheat is a globally vital crop, but its limited genetic variation creates a challenge for breeders aiming to maintain or accelerate agricultural improvements over time. Introducing novel genes and alleles from wheat's wild relatives into the wheat breeding pool via introgression lines is an important component of overcoming this low variation but is constrained by poor genomic resolution and limited understanding of the genomic impact of introgression breeding programmes. By sequencing 17 hexaploid wheat/Ambylopyrum muticum introgression lines and the parent lines, we have precisely pinpointed the borders of introgressed segments, most of which occur within genes. Read More

Plant Dis 2022 May 20. Epub 2022 May 20.

USDA-ARS San Joaquin Valley Agricultural Sciences Center, 57733, Crop Diseases, Pests, and Genetics, Parlier, California, United States;

Huanglongbing (HLB) is a destructive citrus disease that affects production worldwide. " Liberibacter asiaticus" (CLas), a phloem-limited bacterium, is the associated causal agent of HLB. The current standard for detection of CLas is real-time quantitative polymerase chain reaction (qPCR) using either CLas 16S rRNA gene- or the ribonucleotide reductase (RNR) gene-specific primers/probe. Read More

Phytopathology 2022 May 20. Epub 2022 May 20.

New Mexico State University, EPPWS, 3BE Skeen Hall, Las Cruces, New Mexico, United States, 88003;

Scab, caused by the plant pathogenic fungus Venturia effusa, is a major disease of pecan in South America, resulting in loss of quantity and quality of nut yield. Characteristics of the populations of V. effusa in South America are unknown. Read More

Int Ophthalmol 2022 May 20. Epub 2022 May 20.

Department of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, No. 49 Garden North Road, Haidian District, Beijing, 100191, People's Republic of China.

Purpose: To evaluate the clinical outcomes of penetrating keratoplasty (PK) and Descemet's stripping automated endothelial keratoplasty (DSAEK) in eyes with irreversible corneal decompensation secondary to Axenfeld-Rieger syndrome (ARS).

Methods: In this retrospective case series, a total of four eyes undergoing PK and seven eyes undergoing DSAEK, including one eye requiring one repeat DSAEK, between 2014 and 2021 were enrolled. Postoperative complications, graft survival, glaucoma treatment before and after keratoplasty, visual outcomes, and endothelial cell density were recorded. Read More

Anesth Analg 2022 Jun 10;134(6):e36-e37. Epub 2022 May 10.

Department of Anesthesiology CHU Brugmann, Université libre de Bruxelles, Bruxelles, Belgium.

J Anim Sci 2022 May 20. Epub 2022 May 20.

Department of Animal and Range Sciences New Mexico State University, Las Cruces, NM 88003, USA.

Management strategies utilized during pre-breeding development of replacement heifers can impact fertility and the ovarian reserve. Angus-Hereford crossbred heifers (n = 233) were utilized over a three-year period to determine the effects of administration of a growth promoting implant at either branding or weaning on growth, reproduction, and ovarian development. Heifer calves were randomly assigned to one of three treatments: 1) non-implanted controls (CON; n = 79), 2) implanted at approximately 2 mo of age (average calf age = 58 d) with Synovex-C (BIMP, n = 82), or 3) implanted at approximately 7mo of age (average calf age = 210 d) with Synovex-C (WIMP; n = 72). Read More

Front Aging Neurosci 2022 3;14:862098. Epub 2022 May 3.

Department of Anatomy, Research Group for Mood Disorders, Medical School, University of Pécs, Pécs, Hungary.

FOS proteins are early-responding gene products that contribute to the formation of activator protein-1. Several acute and chronic stimuli lead to Fos gene expression, accompanied by an increase of nuclear FOS, which appears to decline with aging. FOSB is another marker to detect acute cellular response, while ΔFOSB mirrors long-lasting changes in neuronal activity upon chronic stress. Read More

Front Plant Sci 2022 21;13:827890. Epub 2022 Apr 21.

Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.

Camphor tree [ (L.) J. Presl], a species in the magnoliid family Lauraceae, is known for its rich volatile oils and is used as a medical cardiotonic and as a scent in many perfumed hygiene products. Read More

ACS Pharmacol Transl Sci 2022 May 3;5(5):373-386. Epub 2022 May 3.

PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany.

The adenosine A receptor (AAR) belongs to the rhodopsin-like G protein-coupled receptor (GPCR) family. It is upregulated under hypoxic conditions, in inflammation and cancer. Previous studies indicated the coupling of the AAR to different G proteins, mainly G, but in some cases G or G, depending on the cell type. Read More

Front Public Health 2022 3;10:797351. Epub 2022 May 3.

The Center of Neuroscience and Sports, Capital University of Physical Education and Sports, Beijing, China.

Background: Tai Chi Chuan (TCC) is an effective method for delaying cognitive decline in older adults. However, in older adults, the association between long-term TCC practice and working memory updating has not been extensively studied.

Objective: This cross-sectional study investigated how updating function operationalized Reaction Times (RTs) and Accuracy Rates (ARs) of N-Back tasks being measured in a laboratory setting is related to long term practice of TCC. Read More

Materials (Basel) 2022 May 9;15(9). Epub 2022 May 9.

Institute of Organic Chemistry (IOC), Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76133 Karlsruhe, Germany.

In this work, the adsorption of Cr(VI) ions and the organic dye Alizarin Red S (ARS) was investigated using magnetite talc ([email protected]) nanocomposite. Different characterization techniques such as scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, X-ray Diffraction (XRD), and thermogravimetric analysis (TGA) were used to demonstrate the physical and chemical properties of the fabricated [email protected] nanocomposite. In addition, the adsorption isothermic, kinetic, and thermodynamic properties were illustrated. Read More

Sensors (Basel) 2022 May 2;22(9). Epub 2022 May 2.

National Research Council of Italy, IMM-Institute for Microelectronics and Microsystems, 73100 Lecce, Italy.

Predicting change from multivariate time series has relevant applications ranging from the medical to engineering fields. Multisensory stimulation therapy in patients with dementia aims to change the patient's behavioral state. For example, patients who exhibit a baseline of agitation may be paced to change their behavioral state to relaxed. Read More

Sensors (Basel) 2022 Apr 29;22(9). Epub 2022 Apr 29.

Department of Information Engineering, University of Florence, 50139 Firenze, Italy.

The Assisted Living Environments Research Area-AAL (Ambient Assisted Living), focuses on generating innovative technology, products, and services to assist, medical care and rehabilitation to older adults, to increase the time in which these people can live. independently, whether they suffer from neurodegenerative diseases or some disability. This important area is responsible for the development of activity recognition systems-ARS (Activity Recognition Systems), which is a valuable tool when it comes to identifying the type of activity carried out by older adults, to provide them with assistance. Read More

Commun Biol 2022 05 19;5(1):477. Epub 2022 May 19.

The Department of Forest and Conservation Sciences, University of British Columbia, Vancouver, BC, Canada.

Invasive exotic pathogens pose a threat to trees and forest ecosystems worldwide, hampering the provision of essential ecosystem services such as carbon sequestration and water purification. Hybridization is a major evolutionary force that can drive the emergence of pathogens. Phytophthora ramorum, an emergent pathogen that causes the sudden oak and larch death, spreads as reproductively isolated divergent clonal lineages. Read More

Stem Cells 2022 May 19. Epub 2022 May 19.

Key Laboratory of Oral Diseases of Jiangsu Province and Stomatological Institute of Nanjing Medical University, Nanjing, Jiangsu, China.

Stem cells from the apical papilla (SCAPs) are important for tooth root development and regeneration of root dentin. Here, we examined the expression of programmed cell death protein-1 (PD-1) in SCAPs and investigated the effect of PD-1 on odontogenic and osteogenic differentiation and the relationship between PD-1 and SHP2/NF-κB signals. SCAPs were obtained and cultured in the related medium. Read More

J Food Prot 2022 May 19. Epub 2022 May 19.

Residue Chemistry and Predictive Microbiology Research unit, U.S. Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, PA 19038-8551.

Consumer safety concerns over established fresh produce washing methods, combined with demand for organic and clean label food, has led to the exploration of novel methods of produce sanitization. Essential oils (EOs), extracted from commonly found plants have potential as clean label sanitizers, as they are naturally derived and act as antimicrobials as well as antioxidants. In this review, the antimicrobial abilities of EOs are explored in the following categories: individually and in-combination, as emulsions, combined with existing chemical and physical preservation methods, incorporated into films and coatings, and in vapor phase. Read More

Phytopathology 2022 May 18. Epub 2022 May 18.

Michigan State University, Department of Plant Pathology, 107 CIPS, East Lansing, Michigan, United States, 48824-1311.

Management of cucurbit downy mildew (CDM) caused by , relies on an intensive fungicide program. In Michigan, CDM occurs annually due to an influx of airborne sporangia; timely alerts of airborne inoculum can assist growers in assessing the need to initiate fungicide sprays. This research aimed to improve the specific detection of airborne sporangia by adapting qPCR-based assays to distinguish among clade I and II and in spore trap samples from commercial production sites and research plots. Read More

Poult Sci 2022 Apr 8;101(7):101911. Epub 2022 Apr 8.

School of Environmental and Rural Sciences, University of New England, Armidale, NSW, 2351, Australia.

An experiment was conducted to evaluate the effects of varying AME concentrations and protease supplementation on broiler performance and jejunal and ileal nutrient digestibility from 1 to 35 d of age. Ross × Ross 308 male broilers (n = 1,008) were equally distributed into 48 floor pens and offered 1 of 6 dietary treatments (8 replicate pens/treatment). Dietary treatments consisted of a factorial arrangement with AME concentration (low-, moderate-, or high-AME) and supplemental protease (without or with) as the main factors. Read More

Arch Insect Biochem Physiol 2022 May 18:e21915. Epub 2022 May 18.

Key Laboratory of Forest Disaster Warning and Control of Yunnan Province, Southwest Forestry University, Kunming, China.

The Wnt gene family is involved in a wide range of developmental processes. Despite its significance, the evolution and function of Wnt genes remain largely unclear. Here, an exhaustive survey of Wnt genes was conducted in Tenebrio molitor and 17 other beetle genomes. Read More