359 results match your criteria AJP reports[Journal]


Pentalogy of Cantrell in Full Term Neonate.

AJP Rep 2019 Apr 9;9(2):e144-e146. Epub 2019 Apr 9.

Medical Student, Lorestan University of Medical Sciences, Khorramabad, Iran.

Pentalogy of Cantrell (PC) is an uncommon congenital disorder characterized by severe defects in the chest and abdomen, including abdominal visceral prolapsed via umbilical cord (omphalocele), defect in the lower part of the sternum, defect in the front of the diaphragm, defects in the anterior part of the pericardium, and the ectopiacordis. Here, we report a 2-hour-old girl, weighing 3,500 g, who was referred to Shahid Madani Hospital in Khorramabad due to the large omphalocele on her chest with pulsating mass above it. The baby was the first child of a 24-year-old mother who was born with an uncomplicated vaginal delivery. Read More

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http://dx.doi.org/10.1055/s-0039-1683936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456328PMC

Effect of a High-Fat Diet and Metformin on Placental mTOR Signaling in Mice.

AJP Rep 2019 Apr 9;9(2):e138-e143. Epub 2019 Apr 9.

Division of Gynecologic Oncology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

 This study was aimed to measure the effects of a high-fat diet and metformin on placental mechanistic target of rapamycin (mTOR) signaling in mice.  Pregnant friend virus B (FVB)-strain mice were allocated on embryonic day (e) 0.5 to one of four groups; group 1: control diet (CD, 10% fat) + control treatment (CT), group 2: CD + metformin treatment (MT), group 3: high-fat diet (HFD, 60% fat) + CT, and group 4: HFD + MT. Read More

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http://dx.doi.org/10.1055/s-0039-1683362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456331PMC

Successful Management of Pulmonary Arterial Hypertension by Monitoring N-Terminal Pro-B-Type Natriuretic Peptide Serum Levels in a Preterm Infant with Chronic Lung Disease: A Case Report.

AJP Rep 2019 Apr 9;9(2):e133-e137. Epub 2019 Apr 9.

Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu, Japan.

We measured the serial changes in N-terminal probrain natriuretic peptide (NT-proBNP) levels in a 6-month-old male infant with chronic lung disease (CLD) complicated by pulmonary arterial hypertension (PAH). The patient was born at the 24th week of gestation weighing 695 g. At 1 month after birth, an echocardiogram confirmed the diagnosis of CLD with PAH. Read More

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http://dx.doi.org/10.1055/s-0039-1684026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456330PMC
April 2019
1 Read

Sonographic Estimated Fetal Weight and Cesarean Delivery among Nulliparous Women with Obesity.

AJP Rep 2019 Apr 9;9(2):e127-e132. Epub 2019 Apr 9.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

 This study was aimed to examine the association between having an ultrasound estimate of fetal weight (US-EFW) and mode of delivery among obese women.  A retrospective cohort study of nulliparous women with a body mass index of ≥ 35 kg/m who delivered term singleton gestations. We examined whether having had an US-EFW within 35 days of delivery, or an US-EFW ≥ 90th percentile for gestational age, was associated with intrapartum cesarean delivery. Read More

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http://dx.doi.org/10.1055/s-0039-1684035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456329PMC
April 2019
1 Read

Prenatal Diagnosis and Successful Palliation of Absent Aortic Valve with Hypoplastic Left Heart Syndrome: A Case Report and Review of Literature.

AJP Rep 2019 Apr 9;9(2):e121-e126. Epub 2019 Apr 9.

Division of Pediatric Cardiology, University of Texas Medical Branch, Galveston, Texas.

 Congenital absence of the aortic valve leaflets is a rare association with hypoplastic left heart syndrome (HLHS).  A 37-year-old pregnant woman was referred for fetal evaluation of possible HLHS at 22 weeks of gestation. The fetal echocardiogram (ECHO) was remarkable for a hypoplastic left atrium, nearly atretic mitral valve, small left ventricle, and a hypoplastic aortic valve with severe aortic insufficiency. Read More

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http://dx.doi.org/10.1055/s-0038-1677480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456327PMC
April 2019
1 Read

Erratum: Persistence of Neonatal Brachial Plexus Palsy among Nulliparous Versus Parous Women.

AJP Rep 2019 Jan 4;9(1):e1. Epub 2019 Apr 4.

Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas.

[This corrects the article DOI: 10.1055/s-0038-1677051.]. Read More

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http://dx.doi.org/10.1055/s-0039-1687855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449157PMC
January 2019

The Value of Different Radiological Modalities in Assessment of Spontaneous Pneumomediastinum: Case Review and Diagnostic Perspective.

AJP Rep 2019 Jan 7;9(1):e72-e75. Epub 2019 Mar 7.

Department of Pediatrics, University of Saskatchewan, Saskatoon, Canada.

Pneumomediastinum (PM), or a mediastinal air leak, is a known morbidity in neonates. Among predisposing factors, the most significant are mixed lung diseases, such as pneumonia or meconium aspiration syndrome, with coexisting atelectasis and airway obstruction. We report an unusual presentation of significant spontaneous pneumomediastinum in a term newborn delivered by elective cesarean section with no history of active resuscitation at birth. Read More

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http://dx.doi.org/10.1055/s-0039-1683862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406024PMC
January 2019
2 Reads

The Effect of Non-penicillin Antibiotic Regimens on Neonatal Outcomes in Preterm Premature Rupture of Membranes.

AJP Rep 2019 Jan 7;9(1):e67-e71. Epub 2019 Mar 7.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology at Duke University Hospital, Durham, North Carolina.

 A 7-day course of a penicillin (PCN) and macrolide is standard of care (SAR) in preterm premature rupture of membranes (PPROM). Data regarding alternative antibiotic regimens are limited. We sought to assess the impact of non-PCN regimens on neonatal outcomes. Read More

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http://dx.doi.org/10.1055/s-0039-1683378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406027PMC
January 2019
1 Read

RNA-Sequencing of Umbilical Cord Blood to Investigate Spontaneous Preterm Birth: A Pilot Study.

AJP Rep 2019 Jan 7;9(1):e60-e66. Epub 2019 Mar 7.

Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

 To analyze the transcriptomic gene expression of umbilical cord blood leukocytes using RNA-sequencing from preterm birth (PTB) and term birth (TB).  Eight women with spontaneous PTB (sPTB) and eight women with unlabored TB were enrolled prospectively. The sPTB and TB cohorts were matched for maternal age, race, mode of delivery, and fetal sex. Read More

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http://dx.doi.org/10.1055/s-0039-1678717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406026PMC
January 2019

Assessing Adverse Childhood Experiences during Pregnancy: Evidence toward a Best Practice.

AJP Rep 2019 Jan 7;9(1):e54-e59. Epub 2019 Mar 7.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of South Carolina School of Medicine Greenville/Greenville Health System, Greenville, South Carolina.

 To quantify the prevalence of adverse childhood experiences (ACEs) among a diverse urban cohort of pregnant women.  The ACE survey was self-administered to 600 women categorized evenly between the waiting room, private examination rooms, and CenteringPregnancy group spaces. The percentage of women willing to complete the survey per location was compared using chi-square tests, and the mean ACE score per arm was compared using Wilcoxon's rank-sum test. Read More

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http://dx.doi.org/10.1055/s-0039-1683407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406025PMC
January 2019

Risk Factors for Very Preterm Births in French Guiana: The Burden of Induced Preterm Birth.

AJP Rep 2019 Jan 4;9(1):e44-e53. Epub 2019 Mar 4.

University of French Guiana, Cayenne General Hospital, Cayenne, French Guiana.

 Early preterm births are still represented as a major public health problem in French Guiana. The objective of the present study was to study factors associated with early preterm birth in French Guiana.  A monocentric age-matched case control study was conducted at the sole level 3 maternity in French Guiana. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1678716
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http://dx.doi.org/10.1055/s-0039-1678716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398999PMC
January 2019
9 Reads

Finding Understudied Disorders Potentially Associated with Maternal Morbidity and Mortality.

AJP Rep 2019 Jan 4;9(1):e36-e43. Epub 2019 Mar 4.

Lister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.

 Clinical research literature focuses primarily on the most common causes of maternal morbidity and mortality (MMM). We explore sections of the discharge summaries of pregnant or postpartum women admitted to an intensive care unit (ICU) to identify associated disorders and mine the literature to identify knowledge gaps in clinical research.  Data for the study were discharge summaries in the MIMIC (Medical Information Mart for Intensive Care) database. Read More

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http://dx.doi.org/10.1055/s-0039-1683363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398998PMC
January 2019
1 Read

How does Fetal Autopsy after Pregnancy Loss or Termination for Anomalies and other Complications Change Recurrence Risk?

AJP Rep 2019 Jan 18;9(1):e30-e35. Epub 2019 Feb 18.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, California.

 Historically, fetal autopsy was common after terminations for anomalies. Previous studies report that fetal autopsy confirms ultrasound findings in the majority of cases. This study aims to examine correlation between prenatal and autopsy diagnoses at University of California, San Francisco (UCSF) and evaluate whether autopsy adds diagnostic information, specifically information that changes risk of recurrence for future pregnancies. Read More

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http://dx.doi.org/10.1055/s-0039-1681013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379179PMC
January 2019

A Novel Treatment for Massive Hemorrhage after Maternal Trauma in Pregnancy.

AJP Rep 2019 Jan 13;9(1):e27-e29. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, University of Arizona, Tucson, Arizona.

 Trauma in pregnancy can lead to life-threatening hemorrhage. Conventional treatments of hemorrhage include medical and surgical management. However, if these measures fail uterine compression is an option to control bleeding. Read More

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http://dx.doi.org/10.1055/s-0039-1678735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374146PMC
January 2019
1 Read

Aortic Arch Thrombosis Associated with Fetal Cytomegalovirus Viremia.

AJP Rep 2019 Jan 1;9(1):e23-e26. Epub 2019 Feb 1.

Pediatric Cardiology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey.

Cytomegalovirus(CMV) associated thrombosis has been reported sporadically in the medical literature; however, its antenatal scenario has not been documented. We herein present the antenatal, Doppler's ultrasound and magnetic resonance angiographic features of thrombosis in the aortic arch showing extension toward the medial lumen of the brachiocephalic trunk with critical occlusion of the left common carotid artery and left subclavian artery in a term fetus to raise obstetricians'/ neonatologists'/pediatric cardiologists' awareness for the association between CMV viremia and intrauterine thrombosis that caused cerebral injury, neurodevelopmental impairment, and permanent sequela. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675631
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http://dx.doi.org/10.1055/s-0038-1675631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358456PMC
January 2019
12 Reads

Obstetrical Outcomes of Head and Neck (Nonthyroid) Cancers: A 27-Year Retrospective Series and Literature Review.

AJP Rep 2019 Jan 29;9(1):e15-e22. Epub 2019 Jan 29.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

 To describe the clinical presentation and obstetrical outcomes of nonthyroid head and neck cancers (HNCs), and to review literature on this rare condition in pregnancy.  Pregnant women with nonthyroid HNC were identified retrospectively from 1990 to 2017. Maternal, neonatal, pregnancy, and demographic data were collected. Read More

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http://dx.doi.org/10.1055/s-0039-1677876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351273PMC
January 2019
5 Reads

Significant Hematochezia and Intracranial Bleeding in Neonatal Hereditary Hemorrhagic Telangiectasia.

AJP Rep 2019 Jan 29;9(1):e10-e14. Epub 2019 Jan 29.

Department of Human Genetics, Emory University, Atlanta, Georgia.

Hereditary hemorrhagic telangiectasia (HHT) is an underreported autosomal dominant vascular dysplasia. Neonatal presentations of HHT are rare, as this disorder typically presents in adolescence or beyond with epistaxis. We report a female neonate with hematochezia on the 1st day of life secondary to multiple gastrointestinal arteriovenous malformations (AVMs) along with intracranial hemorrhage. Read More

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http://dx.doi.org/10.1055/s-0039-1677735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351274PMC
January 2019
2 Reads

Simulation to Improve Trainee Skill and Comfort with Forceps-Assisted Vaginal Deliveries.

AJP Rep 2019 Jan 21;9(1):e6-e9. Epub 2019 Jan 21.

Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California.

 Simulation training is a powerful learning tool for low frequency events. Forceps-assisted vaginal deliveries (FAVD) are an important tool in reducing cesarean deliveries. The aim of this study is to create a high-fidelity simulation-based curriculum for residency education and investigate pre- and posttest skill and confidence. Read More

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http://dx.doi.org/10.1055/s-0039-1677736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340792PMC
January 2019
7 Reads

Persistence of Neonatal Brachial Plexus Palsy among Nulliparous Versus Parous Women.

AJP Rep 2019 Jan 4;9(1):1-5. Epub 2019 Jan 4.

Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas.

 Our objective was to compare persistence of neonatal brachial plexus palsy (NBPP) at 1 and 2 years in children of nulliparous versus parous women.  We conducted a retrospective cohort study of children diagnosed with NBPP followed at the University of Michigan, Interdisciplinary Brachial Plexus Program (UM-BPP). Self-reported demographics, delivery history, including birth weight (BW) < versus ≥ 9 lbs, and presence of shoulder dystocia (SD) were recorded. Read More

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http://dx.doi.org/10.1055/s-0038-1677051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327754PMC
January 2019

Talcum Powder Toxicosis in Pregnancy.

AJP Rep 2018 Oct 28;8(4):e384-e386. Epub 2018 Dec 28.

Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.

 Pica is a relatively common phenomenon in pregnancy and typically includes consumption of nontoxic substances such as earth/clay, raw starches, and ice. Occasionally, substances may be toxic or have unintended consequences.  A nulliparous woman presented to our facility complaining of numerous, vague symptoms that are common in pregnancy. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1676382
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http://dx.doi.org/10.1055/s-0038-1676382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310682PMC
October 2018
7 Reads

Diagnostic Errors in the Neonatal Intensive Care Unit: A Case Series.

AJP Rep 2018 Oct 26;8(4):e379-e383. Epub 2018 Dec 26.

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

Diagnostic errors remain understudied in neonatal intensive care units (NICUs). The few available studies are primarily autopsy-based, and do not evaluate diagnostic errors that did not result in the patient's death. This case series presents 10 examples of nonlethal diagnostic errors in the NICU-classified according to the component of the diagnostic process which led to the error. Read More

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http://dx.doi.org/10.1055/s-0038-1676619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306275PMC
October 2018

Challenges and Limitations of Clinical Trials on Labor Induction: A Review of the Literature.

AJP Rep 2018 Oct 26;8(4):e365-e378. Epub 2018 Dec 26.

Department of Obstetrics, Gynecology and Reproductive Sciences, UTHealth McGovern Medical School, Houston, Texas.

Induction of labor is a common obstetric procedure performed in nearly a quarter of all deliveries in the United States. Pharmacological (prostaglandins, oxytocin) and/or mechanical methods (balloon catheters) are commonly used for labor induction; however, there is ongoing debate as to which method is the safest and most effective. This narrative review discusses key limitations of published trials on labor induction, including the lack of well-designed randomized controlled trials directly comparing specific methods of induction, heterogeneous trial populations, and wide variation in the protocols used and outcomes reported. Read More

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http://dx.doi.org/10.1055/s-0038-1676577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306280PMC
October 2018
1 Read

Pregnancies Complicated by Familial Hypertriglyceridemia: A Case Report.

AJP Rep 2018 Oct 26;8(4):e362-e364. Epub 2018 Dec 26.

Department of Women's Health, Arrowhead Regional Medical Center, Colton, California.

 Although rare, familial hypertriglyceridemia can cause acute and life-threatening complications in pregnancy.  The first patient's pregnancy was complicated by multiple admissions for pancreatitis due to hypertriglyceridemia and noncompliance with gemfibrozil. In her second pregnancy, she was compliant with gemfibrozil and only experienced pancreatitis episodes toward the end of pregnancy. Read More

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http://dx.doi.org/10.1055/s-0038-1676832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306273PMC
October 2018
1 Read

Bronchopulmonary Sequestration with Fetal Hydrops in a Monochorionic Twin Successfully Treated with Multiple Courses of Betamethasone.

AJP Rep 2018 Oct 3;8(4):e359-e361. Epub 2018 Dec 3.

Department of Gynaecology and Obstetrics, Third Faculty of Medicine, Charles University, Prague, Czech Republic.

 We present a case of severe bronchopulmonary sequestration (BPS) and fetal hydrops in one of the monochorionic twin successfully treated with multiple courses of betamethasone.  A 21-year-old gravida 2 para 1 was referred to our hospital for suspected twin-to-twin transfusion syndrome (TTTS) at 28 weeks of gestational age. However, prenatal ultrasound of the larger twin revealed a chest lesion that was associated with significant ascites, massive hydrothorax, scant hepatomegaly, subcutaneous edema, and severe polyhydramnios. Read More

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http://dx.doi.org/10.1055/s-0038-1676339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277237PMC
October 2018
3 Reads

Maternal and Neonatal Outcomes after Attempted External Cephalic Version among Women with One Previous Cesarean Delivery.

AJP Rep 2018 Oct 28;8(4):e349-e354. Epub 2018 Nov 28.

Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, New York.

 This study was aimed to evaluate success rates of (1) external cephalic version (ECV) among women with one prior cesarean delivery (CD) and (2) maternal and neonatal outcomes after ECV among women with prior CD.  Two linked studies using U.S. Read More

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http://dx.doi.org/10.1055/s-0038-1676297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261738PMC
October 2018

Maternal and Fetal Outcomes in Pregnancies affected by Bone and Soft Tissue Tumors.

AJP Rep 2018 Oct 28;8(4):e343-e348. Epub 2018 Nov 28.

Division of Maternal-Fetal Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

 This study was aimed to describe perinatal outcome of a cohort of pregnant patients with bone and soft tissue tumors and to compare the current series with our group's previously reported experience.  Pregnant women diagnosed before and during pregnancy were identified, retrospectively, for the years 2004 to 2014. Relevant maternal and neonatal data were collected. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1676289
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http://dx.doi.org/10.1055/s-0038-1676289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261736PMC
October 2018
10 Reads

Isolated Fetal Cardiac Abnormalities: Are They Really Isolated?

AJP Rep 2018 Oct 30;8(4):e355-e358. Epub 2018 Nov 30.

Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, New York.

 To determine the rate of unsuspected noncardiac abnormalities in newborns suspected to have isolated cardiac abnormalities in the second trimester.  A review of the ultrasound database from the Weill Cornell Medical Center identified fetuses with a suspected cardiac abnormality from January 2006 to November 2016. Cases with prenatally suspected noncardiac structural abnormalities, abnormal fetal or neonatal karyotype or microarray, and those who delivered at an outside institution or underwent abortion were excluded. Read More

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http://dx.doi.org/10.1055/s-0038-1675349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269235PMC
October 2018
3 Reads

Bromocriptine Use in Peripartum Cardiomyopathy: Review of Cases.

AJP Rep 2018 Oct 21;8(4):e335-e342. Epub 2018 Nov 21.

Irvine Department of Obstetrics and Gynecology, University of California, Orange, California.

 This study is to review published cases of peripartum cardiomyopathy (PPCM) treated with bromocriptine and outline pros and cons of the treatment strategy.  Data were collected from PubMed/MedLine, ClinicalTrials.gov; the years 2007 to 2018 were searched for English-language articles. Read More

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http://dx.doi.org/10.1055/s-0038-1675832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249133PMC
October 2018
4 Reads

Introduction of Posterior Axilla Sling Traction in Simulated Shoulder Dystocia.

AJP Rep 2018 Oct 18;8(4):e247-e250. Epub 2018 Oct 18.

Division of MFM, Department of OB/GYN, Naval Medical Center Portsmouth, Portsmouth, Virginia.

 Aim of this study was to introduce posterior axilla sling traction (PAST) in delivering providers and nursing staff as an adjunct to the management of shoulder dystocia and evaluate comfort in performing the maneuver.  A presimulation questionnaire had given to all participants. A brief training on how to perform PAST was also given. Read More

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http://dx.doi.org/10.1055/s-0038-1675350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193804PMC
October 2018
2 Reads

Pregnancy after Aortic Root Replacement in Marfan's Syndrome: A Case Series and Review of the Literature.

AJP Rep 2018 Oct 18;8(4):e234-e240. Epub 2018 Oct 18.

Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.

 We sought to characterize pregnancy-related aortic complications in women with Marfan's syndrome who had prior aortic root replacement.  This is a retrospective case series study and literature review of women with Marfan's syndrome with pregnancy after aortic root replacement. We surveyed women with Marfan's syndrome who had successful pregnancy after aortic root replacement using the Marfan Foundation Website and from two large tertiary care Marfan's clinics. Read More

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http://dx.doi.org/10.1055/s-0038-1675347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193806PMC
October 2018
3 Reads

Heterogeneous Presentation of Neonatal Hemochromatosis in Dichorionic Twins.

AJP Rep 2018 Oct 20;8(4):e332-e334. Epub 2018 Nov 20.

Department of Paediatrics and Adolescent Medicine, University of Hong Kong, Hong Kong, Hong Kong.

Acute liver failure (ALF) in neonates is rare. Although the incidence is reported to be rare, neonatal hemochromatosis (NH) has to be considered as one of the causes of neonatal ALF. We present a pair of dichorionic twin who had a diverse clinical presentation of NH. Read More

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http://dx.doi.org/10.1055/s-0038-1675335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246115PMC
October 2018
37 Reads

Comparison of Birth Outcomes by Gestational Diabetes Screening Criteria.

AJP Rep 2018 Oct 29;8(4):e280-e288. Epub 2018 Oct 29.

Department of Epidemiology and Psychiatry, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

 This study is to examine the association between different diagnostic criteria for gestational diabetes mellitus (GDM) and adverse birth outcomes.  A retrospective cohort study of 5,937 women with a singleton pregnancy was conducted, who completed GDM screening between 24 to 32 weeks gestational age. Four nonoverlapping groups of women defined as: 1) Normal: glucose challenge test (GCT) <130 mg/dL, 2) elevated GCT + normal oral glucose tolerance test (OGTT): abnormal 1 hour GCT + normal 3 hour OGTT, 3) GDM/International Association of Diabetes in Pregnancy Study Group (IADPSG): abnormal 3 hour OGTT by the IADPSG criteria, and 4) GDM/Carpenter-Coustan (CC): diagnosis per CC criteria. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675343
Publisher Site
http://dx.doi.org/10.1055/s-0038-1675343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238203PMC
October 2018
14 Reads

Mermaid Syndrome: A Case Report of a Rare Congenital Anomaly in Full-Term Neonate with Thumb Deformity.

AJP Rep 2018 Oct 14;8(4):e328-e331. Epub 2018 Nov 14.

Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.

The mermaid syndrome (sirenomelia) is an extremely rare anomaly, an incidence of 1 in 100,000 births, in which a newborn born with legs joined together featuring a mermaid-like appearance (head and trunk like humans and tail like fish), and in most cases die shortly after birth. Gastrointestinal and urogenital anomalies and single umbilical artery are clinical outcome of this syndrome. There are two important hypotheses for pathogenesis of mermaid syndrome: vitelline artery steal hypothesis and defective blastogenesis hypothesis. Read More

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http://dx.doi.org/10.1055/s-0038-1669943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235678PMC
October 2018

Use of a Fibrin Sealant Patch at Cesarean for Conservative Management of Morbidly Adherent Placenta.

AJP Rep 2018 Oct 14;8(4):e325-e327. Epub 2018 Nov 14.

Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.

 Morbidly adherent placenta represents a surgical challenge and source of maternal morbidity and mortality. We report the use of a fibrin sealant patch to address hemorrhage associated with a morbidly adherent placenta during cesarean delivery.  A patient underwent repeat cesarean delivery with complete anterior placenta previa and anticipated morbidly adherent placenta. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675848
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http://dx.doi.org/10.1055/s-0038-1675848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235679PMC
October 2018
19 Reads

Recurrent Cholangiocarcinoma in Pregnancy: A Case Report.

AJP Rep 2018 Oct 12;8(4):e261-e263. Epub 2018 Nov 12.

Department of Obstetrics and Gynecology, Cooper University Health Care, Camden, New Jersey.

Hepatobiliary malignancies during pregnancy are extremely rare and portend a poor prognosis. There are only seven published cases of cholangiocarcinoma in an obstetrical patient, all are cases of primary cholangiocarcinoma (1-7). Herein, we describe the first case of recurrent cholangiocarcinoma during pregnancy. Read More

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http://dx.doi.org/10.1055/s-0038-1675376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232044PMC
October 2018
2 Reads

Understanding if, How, and Why Women with Prior Spontaneous Preterm Births are Treated with Progestogens: A National Survey of Obstetrician Practice Patterns.

AJP Rep 2018 Oct 1;8(4):e315-e324. Epub 2018 Nov 1.

Clarity Pharma Research, Limited Liability Corporation, Department of Analytics, Spartanburg, South Carolina.

 In 2017, the Society for Maternal-Fetal Medicine (SMFM) Guideline Committee reaffirmed that 17 -hydroxyprogesterone caproate (17-OHPC) to prevent preterm birth (PTB) is underutilized. We sought to determine what drove progestogen treatment choice of obstetricians managing pregnant women with histories of 1+ singleton spontaneous PTBs (< 37 weeks) who then delivered singleton gestations within the previous 12 months.  We recruited a nationally representative random sample of obstetricians to abstract medical records of study-qualified patients. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675556
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http://dx.doi.org/10.1055/s-0038-1675556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212295PMC
October 2018
14 Reads

Induction of Labor for Maternal Indications at a Periviable Gestational Age; Survey on Management, Reporting and Auditing amongst Dutch Maternal-Fetal Medicine Specialists and Neonatologists.

AJP Rep 2018 Oct 1;8(4):e295-e300. Epub 2018 Nov 1.

Department of Obstetrics and Gynecology, Radboud University Medical Center Nijmegen, Nijmegen, Gelderland, the Netherlands.

 In cases of life-threatening maternal conditions in the periviable period, professionals may consider immediate delivery with fetal demise as a consequence of the treatment. We sought the opinion of involved medical professionals on management, reporting, and auditing in these cases.  We performed an online survey amongst all registered maternal-fetal medicine (MFM) specialists and neonatologists in the Netherlands. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675340
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http://dx.doi.org/10.1055/s-0038-1675340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212294PMC
October 2018
9 Reads

Clinical Insights for Cervical Ripening and Labor Induction Using Prostaglandins.

AJP Rep 2018 Oct 29;8(4):e307-e314. Epub 2018 Oct 29.

Section of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.

Cervical ripening is often the first component of labor induction and is used to facilitate the softening and thinning of the cervix in preparation for labor. Common methods used for cervical ripening include both mechanical (e.g. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675351
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http://dx.doi.org/10.1055/s-0038-1675351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205862PMC
October 2018
19 Reads

Fetal/Neonatal Pericardial Effusion in Down's Syndrome: Case Report and Review of Literature.

AJP Rep 2018 Oct 29;8(4):e301-e306. Epub 2018 Oct 29.

Grace Centre for Newborn Care, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.

We report a preterm (35 weeks) male neonate with Down's syndrome (DS) diagnosed with isolated pericardial effusion (PE) at 20 weeks of gestation. He was born by precipitous delivery, needed no resuscitation and presented within first 24 hours of life with respiratory distress, anemia due to feto-maternal bleed, hypotension, hepatomegaly, and coagulopathy. Postnatal echocardiography confirmed a 5 mm rim of PE without tamponade, normal cardiac structure, and function. Read More

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http://dx.doi.org/10.1055/s-0038-1675337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205858PMC
October 2018
2 Reads

Importance of Individual Elements for Perineal Protection in Childbirth: An Interventional, Prospective Trial.

AJP Rep 2018 Oct 29;8(4):e289-e294. Epub 2018 Oct 29.

Department of Obstetrics and Gynaecology, Herning Regional Hospital, Herning, Denmark.

 To analyze the association between each element of a hands-on intervention in childbirth and the incidence of obstetric anal sphincter injuries (OASIS).  We conducted a prospective, interventional quality improvement project and implemented a care bundle with five elements at an obstetric department in Denmark with 3,000 deliveries annually. We aimed at reducing the incidence of OASIS. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675352
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http://dx.doi.org/10.1055/s-0038-1675352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205860PMC
October 2018
1 Read

Early-Onset Neonatal Sepsis with Extended Spectrum Beta-Lactamase Producing in Infants Born to South and South East Asian Immigrants: A Case Series.

AJP Rep 2018 Oct 29;8(4):e277-e279. Epub 2018 Oct 29.

Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama.

Extended-spectrum -lactamase (ESBL)-producing Enterobacteriaceae represent a major worldwide threat. We present three cases of early onset ESBL sepsis in infants born to families from South and Southeast Asia to inform the practitioner community about this emerging threat. Infants with suspected sepsis, whose mother is from Asia or Southeast Asia, should be suspected of having an infection with an ESBL-producing organism, and practitioners should strongly consider adding a carbapenem to their usual initial antibiotic regimen. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675336
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http://dx.doi.org/10.1055/s-0038-1675336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205855PMC
October 2018
5 Reads

Fetal MRI in the Identification of a Fetal Ventral Wall Defect Spectrum.

AJP Rep 2018 Oct 29;8(4):e264-e276. Epub 2018 Oct 29.

Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana.

 To ascertain if useful criteria for prenatal diagnosis of fetal ventral body wall defects (VBWDs) exists by reviewing published literature on diagnosis of VBWD as compared with our own diagnostic experience.  A comprehensive literature review of diagnostic criteria of fetal VBWD including pentalogy of Cantrell (POC), omphalocele, exstrophy, imperforate anus, spina bifida (OEIS), cloacal exstrophy, limb-body wall complex (LBWC), and body stalk anomaly was performed followed by a retrospective review of all fetal magnetic resonance imaging (MRI) examinations from our medical center over a 2-year period.  Classically, OEIS is omphalocele, bladder exstrophy, imperforate anus, and spina bifida. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675353
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http://dx.doi.org/10.1055/s-0038-1675353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205859PMC
October 2018
4 Reads

Structured Training for Fetal Diagnostic Skills in a Maternal-Fetal Medicine Fellowship.

AJP Rep 2018 Oct 25;8(4):e251-e260. Epub 2018 Oct 25.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

 The American Institute of Ultrasound in Medicine has described what constitutes a detailed fetal anatomic examination but what comprises an appropriate physician training program has not been described. The purpose of this paper is to describe a highly-structured program developed by our center to train maternal-fetal medicine fellows in a systematic approach to fetal diagnostic imaging.  We describe this approach in three phases. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675344
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http://dx.doi.org/10.1055/s-0038-1675344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202070PMC
October 2018
15 Reads

Decidual Vasculopathy in Preeclampsia and Spiral Artery Remodeling Revisited: Shallow Invasion versus Failure of Involution.

Authors:
Peilin Zhang

AJP Rep 2018 Oct 18;8(4):e241-e246. Epub 2018 Oct 18.

Department of Pathology, NYP Brooklyn Methodist Hospital, Brooklyn, New York.

Decidual vasculopathy is commonly associated with preeclampsia and develops in the late pregnancy in the uterine spiral arteries, which were previously remodeled by the extravillous trophoblasts. In normal early pregnancy, trophoblasts invade into the spiral artery, leading to vascular transformation, and this transformation is found to be associated with phenotypic switch of the endovascular trophoblasts to express CD56, a maternal protein likely from the natural killer (NK) cells. These endovascular trophoblasts are diminished at term. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675348
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http://dx.doi.org/10.1055/s-0038-1675348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202578PMC
October 2018
14 Reads

Successful Management of Giant Placental Chorangioma by Microcoil Embolization.

AJP Rep 2018 Oct 15;8(4):e230-e233. Epub 2018 Oct 15.

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Optimal prenatal management of giant placental chorangioma (also known as chorioangioma, angiomyxoma, fibroangiomyxoma, or fibroma) has yet to be determined. Interventions intended to devascularize the tumor such as interstitial laser, bipolar coagulation, fetoscopic laser photocoagulation, and chemical embolization have met mixed results. We report a minimally invasive, extra-amniotic approach, technically similar to cordocentesis, of microcoil embolization of the feeding vessel. Read More

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http://dx.doi.org/10.1055/s-0038-1669944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188883PMC
October 2018

Methemoglobinemia during the Use of Glyceryl Trinitrate Patches in Neonates: Two Case Reports.

AJP Rep 2018 Oct 15;8(4):e227-e229. Epub 2018 Oct 15.

MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom.

Methemoglobinemia can result in severe hypoxia. It has been frequently reported during the use of inhaled nitric oxide, but can occur where nitrate containing medications are used. Glyceryl trinitrate (GTN) patches have been used in the treatment of digital and limb ischemia in prematurely born infants. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1669945
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http://dx.doi.org/10.1055/s-0038-1669945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188887PMC
October 2018
18 Reads

Progressive Devascularization: A Novel Surgical Approach for Placenta Previa.

AJP Rep 2018 Oct 15;8(4):e223-e226. Epub 2018 Oct 15.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch at Galveston, Galveston, Texas.

 The gold standard for antenatal diagnosis of placenta previa is the transvaginal ultrasonography. In placenta previa cases, separation of placental and uterine tissues is challenging even for the most experienced surgeons. Life-threatening obstetrical complications from cesarean deliveries with placenta previa include peripartum hemorrhage, coagulopathy, blood transfusion, peripartum hysterectomy, and multiple organ failure. Read More

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http://dx.doi.org/10.1055/s-0038-1673373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188885PMC
October 2018
1 Read

Sildenafil Use in the Treatment of Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: A Case Series.

AJP Rep 2018 Oct 15;8(4):e219-e222. Epub 2018 Oct 15.

Division of Neonatology, University of Texas Medical Branch, Galveston, Texas.

 This article studies the role of sildenafil in reducing myocardial stress (measured by serial N-terminal pro b-type natriuretic peptide [NTproBNP] levels) secondary to bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH).  This is a case series of three extremely low birth weight infants with severe BPD at 36 weeks' postmenstrual age. All infants had very elevated NTproBNP (> 2,000 ng/dL) levels and echocardiographic evidence of BPD-PH. Read More

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http://dx.doi.org/10.1055/s-0038-1673343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188884PMC
October 2018
1 Read

Safe Motherhood Initiative: Early Impact of Severe Hypertension in Pregnancy Bundle Implementation.

AJP Rep 2018 Oct 11;8(4):e212-e218. Epub 2018 Oct 11.

American College of Obstetricians and Gynecologists District II, Albany, New York.

 To describe the implementation and early results of the American College of Obstetricians and Gynecologists District II Safe Motherhood Initiative's bundle on the timely treatment of severe hypertension in New York State obstetric hospitals.  This is a retrospective comparative study of two time periods during voluntary implementation of the bundle in New York State's obstetric hospitals. The main outcome measure was the administration of an appropriate antihypertensive agent within 1 hour of the second elevated value for all pregnant or postpartum patients with severe hypertension. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1673632
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http://dx.doi.org/10.1055/s-0038-1673632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181646PMC
October 2018
11 Reads

Visual Estimation of Force Applied During Simulated Deliveries Complicated by Shoulder Dystocia.

AJP Rep 2018 Oct 9;8(4):e206-e211. Epub 2018 Oct 9.

Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, Maryland.

 Shoulder dystocia occurs when the fetal head delivers, but the shoulder is lodged behind the pubic symphysis. Training for these emergency deliveries is not optimized, and litigation can occur around a shoulder dystocia delivery.  Evaluate the ability of an outside observer to visually estimate the amount of traction applied to the fetal head during simulated deliveries complicated by shoulder dystocia. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1673377
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http://dx.doi.org/10.1055/s-0038-1673377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177338PMC
October 2018
3 Reads