295 results match your criteria AIDS research and treatment[Journal]


Perceptions of People Living with HIV and HIV Healthcare Providers on Real-Time Measuring and Monitoring of Antiretroviral Adherence Using Ingestible Sensors: A Qualitative Study.

AIDS Res Treat 2020 27;2020:1098109. Epub 2020 May 27.

University of California, Los Angeles, School of Dentistry, Division of Public Health and Community Dentistry, Los Angeles, CA, USA.

Objective: To describe and analyze the perception and attitudes of people living with HIV (PLWH) and HIV HCPs towards medication adherence with a focus on a digital medicine program (DMP) with ingestible sensors (ISs).

Methods: This is a qualitative analysis pilot study of PLWH who were using DMP recruited by purposive sampling. A convenience sample of HCPs was interviewed. Read More

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http://dx.doi.org/10.1155/2020/1098109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296466PMC

Hospitalization and Predictors of Inpatient Mortality among HIV-Infected Patients in Jimma University Specialized Hospital, Jimma, Ethiopia: Prospective Observational Study.

AIDS Res Treat 2020 27;2020:1872358. Epub 2020 May 27.

Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Addis Ababa University, P.O.Box 1176, Addis Ababa, Ethiopia.

Despite the number of patients enrolled in ART is increased, HIV/AIDS continues to constitute a significant proportion of medical admissions and risk of mortality in low- and middle-income countries. As one of these countries, the case in Ethiopia is not different. The aim of this study was thus to assess reasons for hospitalization, discharge outcomes, and predictors of inpatient mortality among people living with HIV (PLWH) in Jimma University Specialized Hospital (JUSH), Jimma, Southwest Ethiopia. Read More

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http://dx.doi.org/10.1155/2020/1872358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273427PMC

Does Isoniazid Preventive Therapy Provide Better Treatment Outcomes in HIV-Infected Individuals in Northern Ethiopia? A Retrospective Cohort Study.

AIDS Res Treat 2020 21;2020:7025738. Epub 2020 Jan 21.

Department of Pharmacology, School of Pharmacy, College of Health Sciences, Mekelle University, Mek'ele, Ethiopia.

Objectives: Early antiretroviral therapy (ART), isoniazid preventive therapy (IPT), and isoniazid-rifapentine (3HP) are effective strategies for preventing tuberculosis (TB) among people living with HIV (PLHIV). The study aimed to determine the effect of IPT on the TB incidence, follow-up CD4 T cells, and all-cause mortality rate. . Read More

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http://dx.doi.org/10.1155/2020/7025738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204289PMC
January 2020

Sociodemographic and Behavioral Factors Associated with HIV Vulnerability according to Sexual Orientation.

AIDS Res Treat 2020 24;2020:5619315. Epub 2020 Jan 24.

Family Health Department, Oswaldo Cruz Foundation, 61760-000, Eusébio, Brazil.

Objective: To analyze sociodemographic and behavioral factors associated with vulnerability to HIV according to sexual orientation.

Method: This is a cross-sectional study conducted using data on 3,818 people in the city of Imperatriz, Brazil, during 2015 and 2016. The survey's questionnaires addressed sociodemographic and behavioral variables. Read More

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http://dx.doi.org/10.1155/2020/5619315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212321PMC
January 2020

Prediction of CD4 T-Lymphocyte Count Using WHO Clinical Staging among ART-Naïve HIV-Infected Adolescents and Adults in Northern Ethiopia: A Retrospective Study.

AIDS Res Treat 2020 30;2020:2163486. Epub 2020 Apr 30.

Tigray Health Research Institute, Mekelle, Tigray, Ethiopia.

Background: WHO clinical staging has long been used to assess the immunological status of HIV-infected patients at initiation of antiretroviral therapy and during treatment follow-up. In setups where CD4 count determination is not readily available, WHO clinical staging is a viable option. However, correlation between CD4 count and WHO clinical staging is not known in an Ethiopian setting, and hence, the main aim of this study was to assess predictability of CD4 T-lymphocyte count using WHO clinical staging among ART-naïve HIV-infected adolescents and adults in northern Ethiopia. Read More

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http://dx.doi.org/10.1155/2020/2163486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210527PMC

Overweight and Obesity among Recipients of Antiretroviral Therapy at HIV Clinics in Gaborone, Botswana: Factors Associated with Change in Body Mass Index.

AIDS Res Treat 2020 4;2020:8016791. Epub 2020 Jan 4.

Department of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.

Background: Factors associated with overweight/obesity among antiretroviral therapy (ART) recipients have not been sufficiently studied in Botswana.

Objectives: To: (i) estimate the prevalence and trends in overweight/obesity by duration of exposure to ART among recipients, (ii) assess changes in BMI categories among ART recipients between their first clinic visit (BMI-1) and their last clinic visit (BMI-2), (iii) identify ART regimen that predicts overweight/obesity better than the others and factors associated with BMI changes among ART recipients.

Methods: A 12-year retrospective record-based review was conducted. Read More

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http://dx.doi.org/10.1155/2020/8016791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199624PMC
January 2020

Viral Load Suppression after Enhanced Adherence Counseling and Its Predictors among High Viral Load HIV Seropositive People in North Wollo Zone Public Hospitals, Northeast Ethiopia, 2019: Retrospective Cohort Study.

AIDS Res Treat 2020 21;2020:8909232. Epub 2020 Apr 21.

College of Health Sciences, Woldia University, Woldia, Ethiopia.

Background: The World Health Organization currently encourages enhanced adherence counseling for human immunodeficiency virus (HIV) seropositive people with a high viral load count before a treatment switch to the second-line regimen, yet little is known about viral load suppression after the outcome of enhanced adherence counseling. Therefore, this study aimed to assess viral suppression after enhanced adherence counseling sessions and its predictors among high viral load HIV seropositive people.

Methods: Institutional-based retrospective cohort study was conducted among 235 randomly selected HIV seropositive people who were on ART and had a high viral load (>1000 copies/ml) from June 2016 to January 2019. Read More

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http://dx.doi.org/10.1155/2020/8909232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191360PMC

Trends and Adaptive Optimal Set Points of CD4 Count Clinical Covariates at Each Phase of the HIV Disease Progression.

AIDS Res Treat 2020 1;2020:1379676. Epub 2020 Mar 1.

School of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, Durban 4000, South Africa.

In response to invasion by the human immunodeficiency virus (HIV), the self-regulatory immune system attempts to restore the CD4 count fluctuations. Consequently, many clinical covariates are bound to adapt too, but little is known about their corresponding new optimal set points. It has been reported that there exist few strongest clinical covariates of the CD4 count. Read More

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http://dx.doi.org/10.1155/2020/1379676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068150PMC

Testing Positive and Disclosing in Pregnancy: A Phenomenological Study of the Experiences of Adolescents and Young Women in Maseru, Lesotho.

AIDS Res Treat 2020 12;2020:6126210. Epub 2020 Feb 12.

Department of Public Health, Sefako Makgatho Health Sciences University, Pretoria, South Africa.

The routine antenatal screening through the prevention of mother to child transmission of HIV (PMTCT) services results in pregnancy being often the point at which an HIV diagnosis is made. Disclosure to partners presents particular complexities during pregnancy. However, research on the pattern and experiences of disclosure in pregnancy is limited in Lesotho, despite the high prevalence of HIV among pregnant women. Read More

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http://dx.doi.org/10.1155/2020/6126210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037533PMC
February 2020

Syndromic versus Laboratory Diagnosis of Sexually Transmitted Infections in Men in Moshi District of Tanzania.

AIDS Res Treat 2020 7;2020:7607834. Epub 2020 Feb 7.

Harvard Medical School, Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.

The syndromic diagnosis of sexually transmitted infections (STIs) is widely recognized as the most practical, feasible, and cost-effective diagnostic tool in resource-limited settings. This study assessed the diagnostic accuracy of syndromic versus laboratory testing of STIs among 794 men randomly selected from the Moshi district of Tanzania. Participants were interviewed with a questionnaire that included questions on history of STIs symptoms. Read More

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http://dx.doi.org/10.1155/2020/7607834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7029278PMC
February 2020

Evaluation of the Management of Patients with Detectable Viral Load after the Implementation of Routine Viral Load Monitoring in an Urban HIV Clinic in Uganda.

AIDS Res Treat 2019 15;2019:9271450. Epub 2019 Dec 15.

Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.

Objective: To describe the clinical decisions taken for patients failing on treatment and possible implementation leakages within the monitoring cascade at a large urban HIV Centre in Kampala, Uganda.

Methods: As per internal clinic guidelines, VL results >1,000 copies/ml are flagged by a quality assurance officer and sent to the requesting clinician. The clinician fills a "decision form" choosing: (1) refer for adherence counselling, (2) repeat VL after 3 months, and (3) switch to second line. Read More

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http://dx.doi.org/10.1155/2019/9271450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942703PMC
December 2019

Child-Centred Care in HIV Service Provision for Children in Resource Constrained Settings: A Narrative Review of Literature.

AIDS Res Treat 2019 26;2019:5139486. Epub 2019 Nov 26.

The Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.

Introduction: Child-centred care approaches are increasingly gaining traction in healthcare; and are being applied in the delivery of HIV care for children in resource constrained settings. However, very little is known about their potential benefits.

Methods: We synthesised literature from primary and secondary publications exploring the philosophical underpinnings of the concept of child-centred care, and its application to HIV service delivery for children in resource constrained settings. Read More

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http://dx.doi.org/10.1155/2019/5139486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899315PMC
November 2019

Corrigendum to "Consistent Condom Use and Associated Factors Among HIV-Positive Clients on Antiretroviral Therapy in North West Ethiopian Health Center, 2016 GC".

AIDS Res Treat 2019;2019:8218107. Epub 2019 Oct 15.

Department of Public Health, Hawassa Health Science College, Hawassa, Ethiopia.

[This corrects the article DOI: 10.1155/2019/7134908.]. Read More

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http://dx.doi.org/10.1155/2019/8218107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885146PMC
October 2019

Clinico-Epidemiological Profile of Children Orphaned due to AIDS Residing in Care Giving Institutions in Coastal South India.

AIDS Res Treat 2019 3;2019:4712908. Epub 2019 Nov 3.

Department of Community Medicine, Kasturba Medical College, Mangalore, Faculty of Health Sciences, Manipal Academy of Higher Education, Manipal, India.

Background: HIV/AIDS has a greater impact on children. Besides being orphaned by the untimely demise of one or both parents due to the disease, these children are more prone for discrimination by the society.

Methods: In this cross-sectional study 86 children orphaned by AIDS residing in care giving institutions for HIV positive children in Mangalore were assessed for their clinico-epidemiological profile and nutritional status. Read More

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http://dx.doi.org/10.1155/2019/4712908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875357PMC
November 2019

Computational Prediction of Subjective Human Immunodeficiency Virus Status in Malawi Using a Random Forest Approach.

AIDS Res Treat 2019 16;2019:5849183. Epub 2019 Sep 16.

Institute of Demography, National Research University-Higher School of Economics, Myasnitskaya, 9/11, Moscow 101000, Russia.

An individual's subjective judgment about his or her Human Immunodeficiency Virus status depends on certain factors, behavioral, health, and sociodemographic alike. This paper aims to develop a model with good accuracy for predicting subjective HIV infection status using the random forest approach. A total of 12,796 responses of Malawians over a 12-year period were assessed. Read More

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http://dx.doi.org/10.1155/2019/5849183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766123PMC
September 2019

Infant Feeding Practices of HIV Positive Mothers and Its Association with Counseling and HIV Disclosure Status in Ethiopia: A Systematic Review and Meta-Analysis.

AIDS Res Treat 2019 1;2019:3862098. Epub 2019 Aug 1.

Department of Pediatrics and Child Health Nursing, College of Medicine and Health Sciences, University of Gondar, Ethiopia.

Introduction: Breastfeeding is the ideal food source for all newborns globally. However, in the era of Human Immune Deficiency Virus (HIV) infection, feeding practice is a challenge due to mother-to-child HIV transmission. Therefore, this systematic review and meta-analysis aimed to estimate the national prevalence of exclusive breastfeeding and mixed feeding practices among HIV positive mothers and its association with counseling and HIV disclosure status to the spouse in Ethiopia. Read More

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http://dx.doi.org/10.1155/2019/3862098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699255PMC

Factors Affecting Psychological Distress among People Living with HIV/AIDS at Selected Hospitals of North Shewa Zone, Amhara Region, Ethiopia.

AIDS Res Treat 2019 22;2019:8329483. Epub 2019 Jul 22.

Debre Berhan University, Department of Psychology, P.O. Box 445, Debre Berhan, Ethiopia.

Background: The new advances for the treatment of HIV infection using Highly Active Antiretroviral Therapy (HAART) have dramatically improved disease prognosis. However, they are living longer with a chronic condition that increases the risk for psychiatric and psychosocial problems. Various studies have linked HIV/AIDS with a number of psychological problems, depression being the most common. Read More

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http://dx.doi.org/10.1155/2019/8329483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679884PMC
July 2019
1 Read

Facilitators to Accessibility of HIV/AIDS-Related Health Services among Transgender Women Living with HIV in Yogyakarta, Indonesia.

AIDS Res Treat 2019 1;2019:6045726. Epub 2019 Jul 1.

College of Medicine and Public Health, Flinders University, GPO Box 2100, Adelaide 5001, South Australia, Australia.

The study aimed to explore facilitators or enabling factors that enhance accessibility (defined as the opportunity to be able to use) to HIV/AIDS-related health services among HIV positive transgender women, also known as in Yogyakarta, Indonesia. A qualitative study employing one-on-one in-depth interviews was conducted from December 2017 to February 2018. Participants were HIV positive recruited using purposive and snowball sampling techniques. Read More

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http://dx.doi.org/10.1155/2019/6045726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634072PMC
July 2019
1 Read

High Human Immunodeficiency Virus (HIV) Viral Load and Coinfection with Viral Hepatitis Are Associated with Liver Enzyme Abnormalities among HIV Seropositive Patients on Antiretroviral Therapy in the Lake Victoria Zone, Tanzania.

AIDS Res Treat 2019 2;2019:6375714. Epub 2019 Jun 2.

Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.

Background: Liver enzymes abnormalities have been found to be common among patients on antiretroviral treatment (ART). Apart from the effects of ART on these changes, other factors that can potentially contribute to the abnormal levels of these enzymes have been found to vary in different geographical locations. This study investigated factors associated with liver enzymes abnormalities among human immunodeficiency virus (HIV) infected individuals on ART from the Lake Victoria zone, Tanzania. Read More

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http://dx.doi.org/10.1155/2019/6375714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582865PMC
June 2019
1 Read

The Incremental Cost of Delivering PrEP as a Bridge to ART for HIV Serodiscordant Couples in Public HIV Care Clinics in Kenya.

AIDS Res Treat 2019 2;2019:4170615. Epub 2019 May 2.

Department of Global Health, University of Washington, 325 Ninth Avenue, Seattle, WA 98104, USA.

Background: In 2016, the Kenyan Ministry of Health (MOH) released guidelines that recommend preexposure prophylaxis (PrEP) for persons with substantial ongoing HIV risk, including those in HIV serodiscordant partnerships. Estimates of the costs of delivering PrEP within Kenyan public health facilities are needed for planning for PrEP scale up.

Methods: We estimated the incremental annual costs of providing PrEP to HIV uninfected partners as a time-limited "bridge" until the infected partner is virally suppressed on ART within HIV serodiscordant couples as part of routine clinic care in Thika, Kenya. Read More

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http://dx.doi.org/10.1155/2019/4170615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521338PMC
May 2019
19 Reads

Delayed Antiretroviral Therapy (ART) Initiation among Hospitalized Adults in a Resource-Limited Settings: A Challenge to the Global Target of ART for 90% of HIV-Infected Individuals.

AIDS Res Treat 2019 1;2019:1832152. Epub 2019 Apr 1.

Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.

Background: Combination antiretroviral therapy (cART) initiation in hospital settings, where individuals often present with undiagnosed, untreated, advanced HIV disease, is not well understood.

Methods: A cross-sectional study was conducted to determine a period prevalence of cART initiation within two weeks of eligibility, as determined at hospitalization. Using a pretested and precoded data extraction tool, data on cART initiation status and reason for not initiating cART was collected. Read More

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http://dx.doi.org/10.1155/2019/1832152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463639PMC
April 2019
2 Reads

Consistent Condom Use and Associated Factors among HIV-Positive Clients on Antiretroviral Therapy in North West Ethiopian Health Center, 2016 GC.

AIDS Res Treat 2019 17;2019:7134908. Epub 2019 Mar 17.

Department of Public Health, Hawassa Health Science College, Hawassa, Ethiopia.

Background: The burden of Human Immune Deficiency Virus or Acquired Immune Deficiency Syndrome is high in sub-Saharan countries including Ethiopia which have over two-thirds of the global HIV burden. Many would argue that consistent condom use is not most effective method for HIV prevention. Condoms offer protection against unwanted pregnancy and some sexually transmitted infections including Human Immune Deficiency Virus, when used correctly and consistently. Read More

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http://dx.doi.org/10.1155/2019/7134908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441518PMC
March 2019
3 Reads

Healthcare Workers' Perspectives on the Barriers to Providing HIV Services to Children in Sub-Saharan Africa.

AIDS Res Treat 2019 3;2019:8056382. Epub 2019 Mar 3.

Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.

Background: In order to accelerate the HIV response to meet the UNAIDS 90-90-90 indicators for children, healthcare workers need to lead a scale-up of HIV services in primary healthcare settings. Such a scale-up will require investigation into existing barriers that prevent healthcare workers from effectively providing those services to children. Furthermore, if the identified barriers are not well understood, designing context-specific and effective public health response programmes may prove difficult. Read More

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http://dx.doi.org/10.1155/2019/8056382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421001PMC
March 2019
23 Reads

Primary HIV Drug Resistance among Recently Infected Cases of HIV in North-West India.

AIDS Res Treat 2019 27;2019:1525646. Epub 2019 Feb 27.

Department of Community Medicine and School of Public Health, Post-Graduate Institute of Medical Education and Research, Chandigarh 160012, India.

Background: Antiretroviral treatment may lead to the emergence of HIV drug resistance, which can be transmitted. HIV primary drug resistance (PDR) is of great public health concern because it has the potential to compromise the efficacy of antiretroviral therapy (ART) at the population level.

Objective: To estimate the level of primary drug resistance among recently infected cases of HIV in 6 ART centres of North-Western India from September 2014 to June 2016. Read More

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http://dx.doi.org/10.1155/2019/1525646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415312PMC
February 2019
7 Reads

Knowledge, Attitude, and Practice of Postexposure Prophylaxis against HIV Infection among Healthcare Workers in Hiwot Fana Specialized University Hospital, Eastern Ethiopia.

AIDS Res Treat 2019 21;2019:7947086. Epub 2019 Feb 21.

Department of Clinical Nursing, College of Medicine and Health Science, Jigjiga University, Jigjiga, Ethiopia.

Background: Postexposure chemoprophylaxis can prevent human immunodeficiency virus (HIV) infection in risk health care workers; however routine adoption of these practices by the workers has been limited.

Methods: A cross-sectional study was conducted on 311 health care workers of Hiwot Fana Specialized University Hospital between February and March 2016. Data was collected using a structured self-administered questionnaire and analysed using STATA 12. Read More

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http://dx.doi.org/10.1155/2019/7947086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409033PMC
February 2019
1 Read

Prevalence of Depressive Symptoms and Associated Factors among HIV-Positive Youth Attending ART Follow-Up in Addis Ababa, Ethiopia.

AIDS Res Treat 2019 2;2019:4610458. Epub 2019 Jan 2.

Department of Epidemiology, Jimma University, Jimma, Ethiopia.

Depression is most frequently and highly occurring common mental disorder in HIV/AIDS patients especially youth living with HIV/AIDS. This study aimed to assess the prevalence and associated factors of depressive symptoms among youth living with Human Immunodeficiency Virus (HIV) attending Antiretroviral Therapy (ART) follow-up at public hospitals in Addis Ababa, Ethiopia. . Read More

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http://dx.doi.org/10.1155/2019/4610458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334359PMC
January 2019
2 Reads

Coping Strategies for Adverse Effects of Antiretroviral Therapy among Adult HIV Patients Attending University of Gondar Referral Hospital, Gondar, Northwest Ethiopia: A Cross-Sectional Study.

AIDS Res Treat 2018 2;2018:1879198. Epub 2018 Dec 2.

Department of Pharmacy, College of Medicine and Health Science, Ambo University, P.O. Box 19, Ambo, Ethiopia.

Background: Adverse effects from antiretroviral therapy (ART) have an impact on quality of life and medication adherence. There is no clear understanding of how people manage the adverse effects of ART. The individual taking medications which cause serious adverse effects may choose to stop or reduce the medications to relieve the adverse effects. Read More

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https://www.hindawi.com/journals/art/2018/1879198/
Publisher Site
http://dx.doi.org/10.1155/2018/1879198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304486PMC
December 2018
17 Reads

Sexual Behavior of Perinatally Infected Youth in Northwest Ethiopia: Implication for HIV Prevention Strategy.

AIDS Res Treat 2018 1;2018:1573845. Epub 2018 Nov 1.

Public Health Department, Medicine and Health Sciences College, Debre Markos University, Debre Markos, Ethiopia.

Background: The major mode of HIV transmission in many resource-limited settings is via heterosexual intercourse, but the primary risk factor for youth is primarily through perinatal infection. With the maturing of the HIV epidemic, youth who acquired the virus perinatally are now reaching adolescence and becoming young adults. There is a paucity of data on the sexual practices of perinatally infected youth in Ethiopia. Read More

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https://www.hindawi.com/journals/art/2018/1573845/
Publisher Site
http://dx.doi.org/10.1155/2018/1573845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236663PMC
November 2018
32 Reads

Pediatric HIV Disclosure in Northern India: Evaluation of Its Prevalence, Perceptions amongst Caregivers, and Its Impact on CLHIV.

AIDS Res Treat 2018 24;2018:2840467. Epub 2018 Oct 24.

Department of Pediatrics, Post Graduate Institute of Medical Education & Research and Dr. Ram Manohar Lohia Hospital, Baba Kharag Singh Marg, New Delhi 110001, India.

Background: With improving standards of care of children living with HIV (CLHIV), pediatric HIV related mortality rates are declining. New challenges like HIV status disclosure are emerging which need to be addressed to ensure their smooth transition into adulthood. Poor disease disclosure rates are observed in CLHIV globally. Read More

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http://dx.doi.org/10.1155/2018/2840467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220414PMC
October 2018
2 Reads

Early Infant Diagnosis Sample Management in Mashonaland West Province, Zimbabwe, 2017.

AIDS Res Treat 2018 26;2018:4234256. Epub 2018 Jul 26.

Department of Community Medicine, University of Zimbabwe, Zimbabwe.

Background: In 2016, Mashonaland West Province had 7.4% (520) dried blood spot (DBS) samples for early infant diagnosis (EID) rejected by the Zimbabwe National Microbiology Reference Laboratory (NMRL). The samples were suboptimal, delaying treatment initiation for HIV-infected children. Read More

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http://dx.doi.org/10.1155/2018/4234256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083648PMC
July 2018
2 Reads

Trauma and Growth: Impact of AIDS Activism.

AIDS Res Treat 2018 24;2018:9696725. Epub 2018 May 24.

Treatment Action Group, New York, NY, USA.

Introduction: Our goal was to assess the long-term impact of AIDS activism of ACT UP/New York on the current adjustment of those who were members during its peak years (1987-1992), including assessment of trauma sequelae as well as posttraumatic growth.

Methods: A 90-minute semistructured interview and 6 validated self-report scales were administered. We relied on purposive and snowball sampling to recruit potential participants. Read More

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http://dx.doi.org/10.1155/2018/9696725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994318PMC
May 2018
4 Reads

Socioeconomic Status and Vulnerability to HIV Infection in Uganda: Evidence from Multilevel Modelling of AIDS Indicator Survey Data.

AIDS Res Treat 2018 7;2018:7812146. Epub 2018 Jun 7.

University of Hull, UK.

Background: There is controversy on the association between socioeconomic status (SES) and HIV infection. Some evidence claims higher SES is negatively associated with HIV infection while others report the reverse.

Objectives: To examine the association between SES and HIV infection in Uganda and to examine whether the SES-HIV relationship varies by gender, rural-urban place of residence, and time (2004-2005 and 2011) in Uganda. Read More

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http://dx.doi.org/10.1155/2018/7812146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011175PMC
June 2018
1 Read

Messaging Circumstances and Economic Pressures as Influences on Linkage to Medical Male Circumcision following Community-Based HIV Testing for Men in Rural Southwest Uganda: A Qualitative Study.

AIDS Res Treat 2018 3;2018:8387436. Epub 2018 May 3.

Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.

Voluntary medical male circumcision (MMC) reduces risk of HIV infection, but uptake remains suboptimal among certain age groups and locations in sub-Saharan Africa. We analysed qualitative data as part of the Linkages Study, a randomized controlled trial to evaluate community-based HIV testing and follow-up as interventions promoting linkage to HIV treatment and prevention in Uganda and South Africa. Fifty-two HIV-negative uncircumcised men participated in the qualitative study. Read More

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http://dx.doi.org/10.1155/2018/8387436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960566PMC
May 2018
19 Reads

Reproduction and Fertility Beliefs, Perceptions, and Attitudes in People Living with HIV.

AIDS Res Treat 2018 1;2018:5349793. Epub 2018 Apr 1.

Section on Infectious Diseases, Wake Forest University Health Sciences, Winston-Salem, NC, USA.

People living with HIV (PLWH) have distinct needs when it comes to reproductive health, specifically regarding fertility, family planning, and pregnancy, and these needs are often complicated by HIV status. While there is ample research that focuses on reproductive health in PLWH through a quantitative lens, there is a lack of research using qualitative methods, namely, the narrative interview model. We searched PubMed and relevant abstracts to identify 72 articles published from 1997 to 2016 that described a qualitative framework for exploring the behaviors and perceptions regarding family planning, abortion, pregnancy, parenthood, fertility, and forced sterility in PLWH. Read More

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http://dx.doi.org/10.1155/2018/5349793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899855PMC
April 2018
2 Reads

Childhood Adversities and Physical and Mental Health Outcomes in Adults Living with HIV: Findings from the Ontario HIV Treatment Network Cohort Study.

AIDS Res Treat 2018 1;2018:2187232. Epub 2018 Mar 1.

Ontario HIV Treatment Network, Toronto, ON, Canada.

We sought to estimate the prevalence of childhood adversity and examine its relationship with health outcomes among people living with HIV. Study participants included 1409 adults living with HIV and receiving care in Toronto, Canada. Data on childhood adversity, health behaviors, HIV outcome measures, depression, and health-related quality of life (HRQOL) were collected through face-to-face interviews and medical records. Read More

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http://dx.doi.org/10.1155/2018/2187232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852860PMC
March 2018
11 Reads

Prevalence and Associated Factors of Depression among PLHIV in Ethiopia: Systematic Review and Meta-Analysis, 2017.

AIDS Res Treat 2018 28;2018:5462959. Epub 2018 Feb 28.

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Background: Depression is a substantial contributor to the global burden of disease and affects people in all communities across the globe. Depression is the most common psychiatric problem associated with HIV/AIDS and half of all PLWHIV with depression go underdiagnosed and untreated. Psychiatric complications of HIVAIDS delay mental health services in less affluent countries. Read More

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https://www.hindawi.com/journals/art/2018/5462959/
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http://dx.doi.org/10.1155/2018/5462959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850898PMC
February 2018
4 Reads

The Palatability of Lopinavir and Ritonavir Delivered by an Innovative Freeze-Dried Fast-Dissolving Tablet Formulation.

AIDS Res Treat 2018 17;2018:5908167. Epub 2018 Jan 17.

PATH, 2201 Westlake Avenue, Suite 200, Seattle, WA 98121, USA.

Negative hedonic sensory qualities of HIV antiretroviral drugs often reduce patient adherence particularly in pediatric populations requiring oral consumption. This study examines the palatability of an innovative delivery mechanism utilizing a freeze-drying-in-blister approach to create fast-dissolving tablets (FDTs) containing a fixed-dose combination of lopinavir and ritonavir (LPV/r). Consumption patterns of solutions during brief-access and long-term testing and baby foodstuff consumption were analyzed to evaluate the orosensory detection and avoidance of placebo FDTs containing no LPV/r (FDT-) and FDTs containing LPV/r (FDT+). Read More

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http://dx.doi.org/10.1155/2018/5908167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822810PMC
January 2018
10 Reads

Nasal Nitric Oxide Levels in HIV Infection: A Cross-Sectional Study.

AIDS Res Treat 2018 9;2018:7645125. Epub 2018 Jan 9.

Division of Pediatric Respiratory Medicine, McGill University Health Center Research Institute, Montreal, QC, Canada.

Introduction: Low levels of nasal NO have been associated with increased propensity to rhinosinusitis and respiratory tract infections. Our objective was to describe nasal NO levels in HIV-infected individuals versus healthy controls and determine possible risk factors for reduced nasal NO levels.

Materials And Methods: HIV-infected individuals and healthy controls were recruited. Read More

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http://dx.doi.org/10.1155/2018/7645125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818882PMC
January 2018
39 Reads

HIV-Stigma in Nigeria: Review of Research Studies, Policies, and Programmes.

AIDS Res Treat 2017 27;2017:5812650. Epub 2017 Dec 27.

Demography and Population Studies Programme, Schools of Public Health and Social Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Nigeria has about 3.8 million people living with HIV, the second largest globally. Stigma and discrimination are major barriers to testing, treatment uptake, and adherence. Read More

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http://dx.doi.org/10.1155/2017/5812650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763061PMC
December 2017
2 Reads

Assessing Very Early Infant Diagnosis Turnaround Times: Findings from a Birth Testing Pilot in Lesotho.

AIDS Res Treat 2017 19;2017:2572594. Epub 2017 Dec 19.

Elizabeth Glaser Pediatric AIDS Foundation, Project SOAR (Supporting Operational AIDS Research), Washington, DC, USA.

Very early infant diagnosis (VEID) (testing within two weeks of life), combined with rapid treatment initiation, could reduce early infant mortality. Our study evaluated turnaround time (TAT) to receipt of infants' HIV test results and ART initiation if HIV-infected, with and without birth testing availability. Data from facility records and national databases were collected for 12 facilities offering VEID, as part of an observational prospective cohort study, and 10 noncohort facilities. Read More

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http://dx.doi.org/10.1155/2017/2572594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749171PMC
December 2017
8 Reads

Challenges in Assessing Outcomes among Infants of Pregnant HIV-Positive Women Receiving ART in Uganda.

AIDS Res Treat 2017 7;2017:3202737. Epub 2017 Dec 7.

Infectious Diseases Institute, Makerere University, Kampala, Uganda.

Since 2012, the WHO recommends lifelong ART with TDF+FTC/3TC+EFV for all HIV-positive pregnant and breastfeeding women (Option B-plus). In this analysis we describe the proportion of early and late transmission in mothers with high retention in Kampala, Uganda. We included 700 pregnant women from January 2012 to August 2014 with a follow-up extended to August 2016; the median age was 31 years (IQR: 26-35), 36. Read More

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http://dx.doi.org/10.1155/2017/3202737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738585PMC
December 2017
2 Reads

HIV among Female Sex Workers in Five Cities in Burkina Faso: A Cross-Sectional Baseline Survey to Inform HIV/AIDS Programs.

AIDS Res Treat 2017 15;2017:9580548. Epub 2017 Nov 15.

Institut de Recherche en Sciences de la Santé (IRSS), Ouagadougou, West Africa, Burkina Faso.

Background: Female sex workers (FSWs) are considered a vulnerable population for HIV infection and a priority for HIV/AIDS response programs. This study aimed to determine HIV prevalence among FSWs in five cities in Burkina Faso.

Methods: FSWs aged 18 and older were recruited using respondent driven sampling (RDS) in five cities (Ouagadougou, Bobo-Dioulasso, Koudougou, Ouahigouya, and Tenkodogo) in Burkina Faso from 2013 to 2014. Read More

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https://www.hindawi.com/journals/art/2017/9580548/
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http://dx.doi.org/10.1155/2017/9580548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705869PMC
November 2017
31 Reads

Conceptualising the Factors Affecting Retention in Care of Patients on Antiretroviral Treatment in Kabwe District, Zambia, Using the Ecological Framework.

AIDS Res Treat 2017 9;2017:7356362. Epub 2017 Nov 9.

School of Public Health, University of the Western Cape, Cape Town, South Africa.

Background: HIV remains a major public health challenge in Zambia. The roll-out of antiretroviral treatment (ART) has engendered new challenges in retention in care.

Objective: To conceptualise the factors affecting retention in care of ART patients at three primary healthcare facilities using the ecological framework. Read More

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http://dx.doi.org/10.1155/2017/7356362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700481PMC
November 2017
27 Reads

Mortality and Its Predictors among HIV Infected Patients Taking Antiretroviral Treatment in Ethiopia: A Systematic Review.

AIDS Res Treat 2017 30;2017:5415298. Epub 2017 Oct 30.

Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Even though the benefit of antiretroviral therapy (ART) is well established, there is a regional variation in the extent of its benefit. The aim of this review is to highlight mortality and its predictors in Ethiopian adult HIV patients who were on ART.

Methods: Relevant articles were searched on PubMed and Google Scholar databases. Read More

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http://dx.doi.org/10.1155/2017/5415298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682904PMC
October 2017
5 Reads

Disclosure of Parental HIV Status to Children: Experiences of Adults Receiving Antiretroviral Treatment at an Urban Clinic in Kampala, Uganda.

AIDS Res Treat 2017 25;2017:3458684. Epub 2017 Oct 25.

Department of Internal Medicine, School of Medicine, Makerere College of Health Sciences, P.O. Box 7072, Kampala, Uganda.

Limited data are available on the experiences of parental HIV disclosure to children in Uganda. We conducted a qualitative study comprising sixteen in-depth interviews and four focus group discussions with parents receiving highly active antiretroviral therapy. Analysis was done using Atlas. Read More

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http://dx.doi.org/10.1155/2017/3458684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676343PMC
October 2017
5 Reads

Quality of Life of People Living with HIV/AIDS in the Ho Municipality, Ghana: A Cross-Sectional Study.

AIDS Res Treat 2017 24;2017:6806951. Epub 2017 Oct 24.

Laboratory Department, Volta Regional Hospital, Ghana Health Service, Ho, Volta Region, Ghana.

Quality of life (QoL) is an important component in the evaluation of the wellbeing of people living with HIV/AIDS (PLHIV). This study was aimed at evaluating the QoL of PLHIV attending the antiretroviral clinics in the Ho municipality. A cross-sectional study was conducted from January 2017 to April 2017 involving 158 purposively selected HIV-positive patients who were attending the antiretroviral clinics both in the Volta Regional Hospital and Ho Municipal Hospital. Read More

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http://dx.doi.org/10.1155/2017/6806951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674481PMC
October 2017
28 Reads

Early Diagnosis of HIV among Infants Born to HIV-Positive Mothers on Option-B Plus in Kampala, Uganda.

AIDS Res Treat 2017 19;2017:4654763. Epub 2017 Oct 19.

Department of Community Health, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.

Introduction: Globally, there is delay in accessing early HIV diagnosis (EID) among HIV exposed infants (HEIs). With paucity of data on EID use at Kisenyi Health Center, this study assessed factors associated with EID use among HEIs (HIV exposed infants).

Method: This was a cross-sectional study of 246 HIV-positive mother-baby pairs. Read More

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http://dx.doi.org/10.1155/2017/4654763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671668PMC
October 2017
6 Reads

Lipodystrophy among HIV-Infected Patients Attending Care and Treatment Clinics in Dar es Salaam.

AIDS Res Treat 2017 11;2017:3896539. Epub 2017 Oct 11.

Department of Behavioral Sciences, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, Dar es Salaam, Tanzania.

Background: HIV infection and long-term HAART use are associated with metabolic and morphological changes. We assessed prevalence, types, and risk factors associated with lipodystrophy among HIV-infected adults attending CTC in Dar es Salaam, Tanzania.

Methods: Analysis included 466 HIV-infected patients. Read More

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https://www.hindawi.com/journals/art/2017/3896539/
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http://dx.doi.org/10.1155/2017/3896539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660755PMC
October 2017
15 Reads