17,085 results match your criteria AIDS policy & law[Journal]


The Ethics of Breastfeeding by Women Living with HIV/AIDS: A Concrete Proposal for Reforming Department of Health and Human Services Recommendations.

J Law Med Ethics 2019 Mar;47(1):161-164

Lawrence O. Gostin, J.D., LL.D. (Hon.), is O'Neill Professor of Global Health Law, Director of the O'Neill Institute for National and Global Health Law, and Director of the World Health Organization Collaborating Center on Public Health Law and Human Rights. President Obama appointed Prof. Gostin to the National Cancer Advisory Board. Matthew M. Kavanagh, Ph.D., is a visiting professor at Georgetown University Law Center and director of the Global Health Policy and Governance Initiative at the O'Neill Institute.

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http://dx.doi.org/10.1177/1073110519840496DOI Listing

Early outcomes after implementation of treat all in Rwanda: an interrupted time series study.

J Int AIDS Soc 2019 Apr;22(4):e25279

Department of Medicine, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA.

Introduction: Nearly all countries in sub-Saharan Africa have adopted policies to provide antiretroviral therapy (ART) to all persons living with HIV (Treat All), though HIV care outcomes of these programmes are not well-described. We estimated changes in ART initiation and retention in care following Treat All implementation in Rwanda in July 2016.

Methods: We conducted an interrupted time series analysis of adults enrolling in HIV care at ten Rwandan health centres from July 2014 to September 2017. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jia2.25279
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http://dx.doi.org/10.1002/jia2.25279DOI Listing
April 2019
1 Read

Changes in patterns of retention in HIV care and antiretroviral treatment in Tanzania between 2008 and 2016: an analysis of routinely collected national programme data.

J Glob Health 2019 Jun;9(1):010424

Strategic Information Unit, National AIDS Control Programme, Dodoma Tanzania.

Background: Tanzania is a high HIV burden country in Sub-Saharan Africa with 1.5 million people infected. Unless monitored and responded to, low levels of retention in care may lead to poor HIV associated clinical outcomes and an increased likelihood of onward viral transmission. Read More

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http://dx.doi.org/10.7189/jogh.09.010424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445500PMC

Model-Based Methods to Translate Adolescent Medicine Trials Network for HIV/AIDS Interventions Findings Into Policy Recommendations: Rationale and Protocol for a Modeling Core (ATN 161).

JMIR Res Protoc 2019 Apr 16;8(4):e9898. Epub 2019 Apr 16.

Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, United States.

Background: The United States Centers for Disease Control and Prevention estimates that approximately 60,000 US youth are living with HIV. US youth living with HIV (YLWH) have poorer outcomes compared with adults, including lower rates of diagnosis, engagement, retention, and virologic suppression. With Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) support, new trials of youth-centered interventions to improve retention in care and medication adherence among YLWH are underway. Read More

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http://dx.doi.org/10.2196/resprot.9898DOI Listing

A New Generation of Drug Users in St. Petersburg, Russia? HIV, HCV, and Overdose Risks in a Mixed-Methods Pilot Study of Young Hard Drug Users.

AIDS Behav 2019 Apr 11. Epub 2019 Apr 11.

Support, Research and Development Center, Kyiv, Ukraine.

Russia has a widespread injection drug use epidemic with high prevalence of HIV and HCV among people who inject drugs (PWID). We conducted a mixed methods study of young (age 18-26) hard drug users in St. Petersburg. Read More

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http://dx.doi.org/10.1007/s10461-019-02489-6DOI Listing

Psychosocial Factors Associated with Food Insufficiency Among People Living with HIV/AIDS (PLWH) Initiating ART in Ethiopia.

AIDS Behav 2019 Apr 15. Epub 2019 Apr 15.

Institute for Implementation Science in Population Health, City University of New York, 55 West 125th Street, New York, NY, 10027, USA.

Food insufficiency is associated with suboptimal HIV treatment outcomes. Less is known about psychosocial correlates of food insufficiency among PLWH. This sample includes 1176 adults initiating antiretroviral therapy at HIV clinics in Ethiopia. Read More

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http://dx.doi.org/10.1007/s10461-019-02505-9DOI Listing

Turning Feed-forward and Feedback Processes on Patient-reported Data into Intelligent Action and Informed Decision-making: Case Studies and Principles.

Med Care 2019 May;57 Suppl 5 Suppl 1:S31-S37

Patient Reported Outcomes, Dartmouth Hitchcock Medical Center.

Introduction: The collection of patient-reported outcomes (PROs) in routine clinical practice provides opportunities to "feed-forward" the patient's perspective to his/her clinical team to inform planning and management. This data can also be aggregated to "feedback" population-level analytics that can inform treatment decision-making, predictive modeling, population-based care, and system-level quality improvement efforts.

Methods Aiding Interpretation And Acting On Results: Three case studies demonstrate a number of system-level features which aid effective PRO interpretation: (1) feed-forward and feedback information flows; (2) score interpretation aids; (3) cascading measurement; (4) registry-enabled learning health care systems; and (5) the maturational development of information systems. Read More

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http://dx.doi.org/10.1097/MLR.0000000000001088DOI Listing
May 2019
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Pursuing use of optimal formulations for paediatric HIV epidemic control - a look at the use of LPV/r oral pellets and oral granules.

J Int AIDS Soc 2019 Apr;22(4):e25267

United States Agency for International Development, Washington, DC, USA.

Introduction: Despite a significant reduction in mother-to-child transmission of HIV, an estimated 180,000 children were infected with HIV in 2017, and only 52% of children under 15 years of age living with HIV (CLHIV) are on life-saving antiretroviral therapy (ART). Without effective treatment, half of CLHIV die before the age of two years and only one in five survives to five years of age.

Discussion: Over the past four years, the United States Food and Drug Administration tentatively approved new formulations of lopinavir/ritonavir (LPV/r) in the form of oral pellets and oral granules. Read More

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http://dx.doi.org/10.1002/jia2.25267DOI Listing

Hepatitis B virus infection in children and adolescents.

Lancet Gastroenterol Hepatol 2019 Apr 10. Epub 2019 Apr 10.

Global Hepatitis Programme and HIV Department, World Health Organization, Geneva, Switzerland.

Hepatitis B virus (HBV) infection is a major cause of acute and chronic liver disease and associated morbidity and mortality worldwide. Vertical (mother-to-child) and horizontal early childhood transmission are the main routes of HBV transmission and are responsible for most chronic infections, including among adults who bear the greatest burden of morbidity and mortality. Universal hepatitis B immunisation at birth and in infancy is the key strategy for global elimination of HBV infection, and has been highly effective in reducing new vertical infections. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24681253193004
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http://dx.doi.org/10.1016/S2468-1253(19)30042-1DOI Listing
April 2019
1 Read

Hepatitis C virus infection in children and adolescents.

Lancet Gastroenterol Hepatol 2019 Apr 10. Epub 2019 Apr 10.

Global Hepatitis Programme and HIV Department, World Health Organization, Geneva, Switzerland.

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and associated morbidity and mortality worldwide. Short-course, oral, curative, direct-acting antiviral regimens have transformed treatment for HCV infection. Since the 2016 launch of the first global strategy towards elimination of viral hepatitis as a public health threat by 2030, the predominant focus of the global response has been on the treatment of adults, who bear the greatest burden of morbidity and mortality of HCV-related chronic liver disease. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24681253193004
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http://dx.doi.org/10.1016/S2468-1253(19)30046-9DOI Listing
April 2019
1 Read

Exploring Social Determinants of Health as Predictors of Mortality During 2012-2016, Among Black Women with Diagnosed HIV Infection Attributed to Heterosexual Contact, United States.

J Racial Ethn Health Disparities 2019 Apr 12. Epub 2019 Apr 12.

Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, 1600 Clifton Rd., Mailstop E-47, Atlanta, GA, 30329, USA.

Background: In 2016, black women with HIV infection attributed to heterosexual contact accounted for 47% of all women living with diagnosed HIV, and 41% of deaths that occurred among women with diagnosed HIV in the USA that year. Social determinants of health have been found to be associated with mortality risk among people with HIV. We analyzed the role social determinants of health may have on risk of mortality among black women with HIV attributed to heterosexual contact. Read More

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http://dx.doi.org/10.1007/s40615-019-00589-6DOI Listing

Factors associated with risk of HIV-infection among pregnant women in Cameroon: Evidence from the 2016 national sentinel surveillance survey of HIV and syphilis.

PLoS One 2019 12;14(4):e0208963. Epub 2019 Apr 12.

National AIDS Control Committee, Yaoundé, Cameroon.

Background: Human Immunodeficiency Virus infection (HIV) remains a public health concern in Cameroon that requires regular surveillance for informed policy-making to guide programmatic interventions. Using data from the 2016 HIV national sentinel survey in Cameroon, we ascertained HIV prevalence and factors associated with risk of infection among pregnant women.

Methods: A cross-sectional study was conducted throughout 2016 in the 10 regions of Cameroon, targeting 7000 first antenatal care (ANC-1) attendees (4000 from urban and 3000 from rural areas) in 60 sentinel health facilities. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208963PLOS

Smoking cessation for people with severe mental illness (SCIMITAR+): a pragmatic randomised controlled trial.

Lancet Psychiatry 2019 Apr 8. Epub 2019 Apr 8.

Somerset Partnership NHS Foundation Trust, South Petherton, UK.

Background: People with severe mental illnesses such as schizophrenia are three times more likely to smoke than the wider population, contributing to widening health inequalities. Smoking remains the largest modifiable risk factor for this health inequality, but people with severe mental illness have not historically engaged with smoking cessation services. We aimed to test the effectiveness of a combined behavioural and pharmacological smoking cessation intervention targeted specifically at people with severe mental illness. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22150366193004
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http://dx.doi.org/10.1016/S2215-0366(19)30047-1DOI Listing
April 2019
2 Reads

Ways of coping and HIV disclosure among people living with HIV: mediation of decision self-efficacy and moderation by sex.

AIDS Care 2019 Apr 12:1-10. Epub 2019 Apr 12.

e Department of Mental Health Law and Policy, College of Behavioral and Community Sciences , University of South Florida , Tampa , FL , USA.

Individuals living with HIV/AIDS face several stressors and use varying strategies to cope. Disclosure (or nondisclosure) of HIV serostatus is an important consideration among individuals living with HIV. However, studies examining the association between coping and HIV disclosure are lacking, and more research examining potential mediators and moderators is needed. Read More

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http://dx.doi.org/10.1080/09540121.2019.1605045DOI Listing

How Can Programs Better Support Female Sex Workers to Avoid HIV Infection in Zimbabwe? A Prevention Cascade Analysis.

J Acquir Immune Defic Syndr 2019 May;81(1):24-35

Department of Social and Environmental Health Research, Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.

Background: "HIV prevention cascades" have been proposed to support programs by identifying gaps in demand for, access to, and capability to adhere to HIV prevention tools, but there are few empirical examples to guide development. We apply a prevention cascade framework to examine prevention coverage and factors associated with condoms and/or PrEP adherence among female sex workers.

Setting: Seven sites across Zimbabwe. Read More

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http://dx.doi.org/10.1097/QAI.0000000000001980DOI Listing
May 2019
4.556 Impact Factor

Race differences in change in physical functioning in older male veterans with HIV.

AIDS Res Hum Retroviruses 2019 Apr 9. Epub 2019 Apr 9.

Duke University, Center for the Study of Aging and Human Development, Durham, North Carolina, United States ;

Background: Little is known about longitudinal change in physical functioning of older African-American/Black and White HIV-infected persons.

Methods: We examined up to 10 years of data on African-American (N=1157) and White (N=400) men with HIV infection and comparable HIV-negative men (Ns: 1137, 530), age 50-91 from the Veterans Aging Cohort Study Survey sample. Physical functioning was assessed using the SF-12 physical component summary (PCS) score. Read More

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http://dx.doi.org/10.1089/AID.2018.0296DOI Listing

Healthcare Options for People Experiencing Depression (HOPE*D): the development and pilot testing of an encounter-based decision aid for use in primary care.

BMJ Open 2019 Apr 8;9(4):e025375. Epub 2019 Apr 8.

The Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.

Objective: To develop and pilot an encounter-based decision aid (eDA) for people with depression for use in primary care.

Design: We developed an eDA for depression through cognitive interviews and pilot tested it using a one-group pretest, post-test design in primary care. Feasibility, fidelity of eDA use and acceptability were assessed using recruitment rates and semistructured interviews with patients, medical assistants and clinicians. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02537
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http://dx.doi.org/10.1136/bmjopen-2018-025375DOI Listing
April 2019
5 Reads

University students' behaviours towards accessing sexual health information and treatment.

Int J STD AIDS 2019 Apr 8:956462419828866. Epub 2019 Apr 8.

3 Centre for Criminal Justice and Criminology, Swansea University, Swansea, UK.

Globally, it is widely recognised that young people (those under the age of 25 years) are at a higher risk of developing sexually transmitted infections (STIs). The majority of university students studying in the UK fall within this age bracket, and to help prevent such high incidence of STIs in this age group, it is essential that advice and treatment, if required, are obtained from reliable sources. This study sought to explore sources of sexual heath advice and treatment for students at Welsh universities (n = 3007). Read More

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http://dx.doi.org/10.1177/0956462419828866DOI Listing
April 2019
7 Reads

Changes in the utilization patterns of antifungal agents, medical cost and clinical outcomes of candidemia from the health-care benefit expansion to include newer antifungal agents.

Int J Infect Dis 2019 Apr 5. Epub 2019 Apr 5.

Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address:

Objectives: In 2014, South Korea expanded its national health insurance coverage to include newer antifungal agents, such as echinocandins. This study aimed to investigate the effects of policy change on the prescription patterns of antifungals, medical costs and clinical outcomes of candidemia.

Methods: This retrospective cohort enrolled hospitalized patients with candidemia at three tertiary care hospitals in South Korea from January 2012 to December 2015. Read More

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http://dx.doi.org/10.1016/j.ijid.2019.03.039DOI Listing

HIV and HCV Epidemics: Lessons for Lawyers and Policymakers.

Authors:
Michael Kirby

J Law Med 2019 Apr;26(3):583-594

Justice of the High Court of Australia (1996-2009); Patron of the Kirby Institute, UNSW (2011-); Patron of the Community Restorative Centre (2012-).

This article arises from a summary offered by the author to an international conference held at Wilton Park, England, on policy and action necessary to respond effectively to the epidemics caused by the Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV). The article begins with 10 lessons derived by the author from his involvement with the HIV epidemic since 1989. These lessons compare and contrast the features of the HIV/AIDS epidemic and those of the HCV epidemic. Read More

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April 2019
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Incentives Versus Defaults: Cost-Effectiveness of Behavioral Approaches for HIV Screening.

AIDS Behav 2019 Apr 5. Epub 2019 Apr 5.

School of Public Health, University of California Berkeley, Berkeley, CA, USA.

Many HIV positive individuals are still undiagnosed, which has led health systems to try many approaches to expand HIV testing. In a randomized controlled trial, we found that behavioral economics interventions (opt-out testing and financial incentives) each improved HIV testing rates and these approaches are being implemented by several hospital systems. However, it is unclear if these strategies are cost-effective. Read More

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http://dx.doi.org/10.1007/s10461-019-02425-8DOI Listing

Modelling the potential impact of providing pre-exposure prophylaxis (PrEP) in pregnant and breastfeeding women in South Africa.

AIDS 2019 Apr 3. Epub 2019 Apr 3.

Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa.

Objective: HIV-uninfected pregnant and breastfeeding women are at high risk of HIV acquisition, contributing to vertical transmission. Pre-exposure prophylaxis (PrEP) is safe in pregnancy, but PrEP in pregnancy is not policy in many countries including South Africa (SA). We evaluated the potential impact of providing PrEP for pregnant/breastfeeding women using a HIV model for SA. Read More

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http://dx.doi.org/10.1097/QAD.0000000000002221DOI Listing
April 2019
4 Reads

Intergenerational Trauma: The Relationship Between Residential Schools and the Child Welfare System Among Young People Who Use Drugs in Vancouver, Canada.

J Adolesc Health 2019 Apr 1. Epub 2019 Apr 1.

BC Centre on Substance Use, Vancouver, British Colombia, Canada; School of Public Policy, Simon Fraser University, Vancouver, British Columbia, Canada.

Purpose: This study investigated the relationship between familial residential school system (RSS) exposure and personal child welfare system (CWS) involvement among young people who use drugs (PWUD).

Methods: Data were obtained from two linked cohorts of PWUD in Vancouver, Canada, and restricted to Indigenous participants. Multivariable logistic regression analysis was used to investigate the relationship between three categories of familial RSS exposure (none, grandparent, and parent) and CWS involvement. Read More

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http://dx.doi.org/10.1016/j.jadohealth.2019.01.022DOI Listing

Challenges and Opportunities for Lung Cancer Screening in Rural America.

J Am Coll Radiol 2019 Apr;16(4 Pt B):590-595

Rural and Minority Health Research Center, University of South Carolina, Columbia, South Carolina; Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, South Carolina. Electronic address:

Rural populations have higher rates of smoking and both lung cancer incidence and mortality compared with their urban peers. As such, it is imperative that high-risk, rural populations have access to recommended low-dose CT (LDCT) screening, which can detect lung cancer at an earlier, more treatable stage. Data from the 2015 National Health Interview Survey, a nationally representative survey, were analyzed to assess nonmetropolitan-metropolitan and geographic differences in LDCT utilization among screening-eligible individuals. Read More

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http://dx.doi.org/10.1016/j.jacr.2019.01.001DOI Listing

Work and home productivity of people living with HIV in Zambia and South Africa.

AIDS 2019 May;33(6):1063-1071

Department of Infectious Disease Epidemiology, Imperial College London, London, UK.

Objective: To compare number of days lost to illness or accessing healthcare for HIV-positive and HIV-negative individuals working in the informal and formal sectors in South Africa and Zambia.

Design: As part of the HPTN 071 (PopART) study, data on adults aged 18-44 years were gathered from cross-sectional surveys of random general population samples in 21 communities in Zambia and South Africa. Data on the number of productive days lost in the last 3 months, laboratory-confirmed HIV status, labour force status, age, ethnicity, education, and recreational drug use was collected. Read More

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http://dx.doi.org/10.1097/QAD.0000000000002160DOI Listing
May 2019
2 Reads
5.554 Impact Factor

AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study.

BMJ Open 2019 Apr 1;9(4):e026288. Epub 2019 Apr 1.

Department of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.

Introduction: Cryptococcal meningitis is responsible for around 15% of all HIV-related deaths globally. Conventional treatment courses with amphotericin B require prolonged hospitalisation and are associated with multiple toxicities and poor outcomes. A phase II study has shown that a single high dose of liposomal amphotericin may be comparable to standard treatment. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-026288DOI Listing
April 2019
1 Read

"We have a stronger survival mode": exploring knowledge gaps and culturally sensitive messaging of PrEP among Latino men who have sex with men and Latina transgender women in Los Angeles, CA.

AIDS Care 2019 Apr 2:1-7. Epub 2019 Apr 2.

c RAND Corporation, Behavioral and Policy Sciences , Santa Monica , CA , USA.

Latino men who have sex with men (LMSM) and Latina transgender women (LTGW) often lack access to HIV prevention information and strategies such as pre-exposure prophylaxis (PrEP). We explored knowledge gaps and culturally sensitive messaging about PrEP among HIV-negative LMSM and LTGW in Los Angeles. We recruited participants from a Latinx LGBT community-based organization. Read More

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http://dx.doi.org/10.1080/09540121.2019.1601669DOI Listing
April 2019
1 Read

Cervical cancer screening decentralized policy adaptation: an African rural-context-specific systematic literature review.

Glob Health Action 2019 ;12(1):1587894

s Department of Family Medicine, Center for Global Health, Institute for Health Research and Policy, Cancer Center , University of Illinois at Chicago (UIC) , Chicago , IL , USA.

Background: Worldwide, nearly 570,000 women are diagnosed with cervical cancer each year, with 85% of new cases in low- and middle-income countries. The African continent is home to 35 of 40 countries with the highest cervical cancer mortality rates. In 2014, a partnership involving a rural region of Senegal, West Africa, was facing cervical cancer screening service sustainability barriers and began adapting regional-level policy to address implementation challenges. Read More

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http://dx.doi.org/10.1080/16549716.2019.1587894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450494PMC
January 2019

Multifactorial discrimination, discrimination salience, and prevalent experiences of internalized homophobia in middle-aged and older MSM.

Aging Ment Health 2019 Apr 2:1-8. Epub 2019 Apr 2.

g Division of Infectious Diseases , Georgetown University Department of Medicine , Washington , DC , USA.

Objectives: We sought to test whether discrimination salience and multifactorial discrimination were associated with prevalent experiences of internalized homophobia among middle-aged and older men who have sex with men (MSM).

Methods: We analyzed data from 498 middle-aged and older MSM from the Multicenter AIDS Cohort Study (MACS) who reported any lifetime discrimination experience. We estimated the prevalence ratio of current internalized homophobia using multivariable Poisson regressions, accounting for discrimination salience, multifactorial discrimination, and covariates. Read More

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http://dx.doi.org/10.1080/13607863.2019.1594161DOI Listing

Primary HIV Drug Resistance among Recently Infected Cases of HIV in North-West India.

AIDS Res Treat 2019 27;2019:1525646. Epub 2019 Feb 27.

Department of Community Medicine and School of Public Health, Post-Graduate Institute of Medical Education and Research, Chandigarh 160012, India.

Background: Antiretroviral treatment may lead to the emergence of HIV drug resistance, which can be transmitted. HIV primary drug resistance (PDR) is of great public health concern because it has the potential to compromise the efficacy of antiretroviral therapy (ART) at the population level.

Objective: To estimate the level of primary drug resistance among recently infected cases of HIV in 6 ART centres of North-Western India from September 2014 to June 2016. Read More

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http://dx.doi.org/10.1155/2019/1525646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415312PMC
February 2019
4 Reads

Risks and Benefits of Dolutegravir- and Efavirenz-Based Strategies for South African Women With HIV of Child-Bearing Potential: A Modeling Study.

Ann Intern Med 2019 Apr 2. Epub 2019 Apr 2.

Massachusetts General Hospital, Harvard Medical School, and Brigham and Women's Hospital, Boston, Massachusetts (R.P.W.).

Background: Dolutegravir is superior to efavirenz for HIV antiretroviral therapy (ART) but may be associated with an increased risk for neural tube defects (NTDs) in newborns if used by women at conception.

Objective: To project clinical outcomes of ART policies for women of child-bearing potential in South Africa.

Design: Model of 3 strategies: efavirenz for all women of child-bearing potential (EFV), dolutegravir for all women of child-bearing potential (DTG), or World Health Organization (WHO)-recommended efavirenz without contraception or dolutegravir with contraception (WHO approach). Read More

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http://dx.doi.org/10.7326/M18-3358DOI Listing
April 2019
4 Reads

Revisiting aid dependency for HIV programs in Sub-Saharan Africa.

Public Health 2019 Mar 29;170:57-60. Epub 2019 Mar 29.

Department of Pediatrics and Child Health, College of Medicine, University of Nigeria, Nsukka, Enugu, Nigeria; HealthySunrise Foundation, Las Vegas, NV, USA.

Objective: The overall increase in global domestic HIV expenditure obscures the specific performances of many sub-Saharan Africa (SSA) countries in local resourcing of their HIV programs. In this study, we explored the pattern and correlates of domestic HIV expenditure in SSA.

Study Design: This is a cross-sectional ecological study. Read More

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http://dx.doi.org/10.1016/j.puhe.2019.02.016DOI Listing

Acceptability and outcomes of distributing HIV self-tests for male partner testing in Kenyan maternal child health and family planning clinics.

AIDS 2019 Mar 29. Epub 2019 Mar 29.

Department of Global Health, University of Washington, Seattle, Washington.

Background: Providing HIV self-tests to women for distribution to male partners may provide a unique opportunity to increase male partner and couples testing among women in HIV high-burden settings.

Methods: Between November 2017 and June 2018, we offered self-tests for at-home couples or partner HIV-testing to HIV-uninfected women seeking routine maternal child health (MCH) and family planning (FP) services at 8 facilities in Kisumu, Kenya. Women accepting self-tests were offered ≥2 self-tests (OraQuick) to take to their partner(s) with instructions on use. Read More

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http://Insights.ovid.com/crossref?an=00002030-900000000-9694
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http://dx.doi.org/10.1097/QAD.0000000000002211DOI Listing
March 2019
4 Reads
5.554 Impact Factor

A Mixed Methods Study of Anticipated and Experienced Stigma in Health Care Settings Among Women Living with HIV in the United States.

AIDS Patient Care STDS 2019 Apr;33(4):184-195

16 Department of Health Care Organization and Policy, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.

Among places where people living with HIV experience and anticipate HIV-related stigma, stigma in health care settings may be particularly harmful. Utilizing an exploratory sequential mixed methods approach, we conducted interviews (n = 76) and questionnaires (N = 460) with older adult women living with HIV enrolled in the Women's Interagency HIV Study in Birmingham, AL; Jackson, MS; Atlanta, GA; and San Francisco, CA. Interviews addressed facilitators and barriers to HIV treatment adherence, including HIV-related stigma. Read More

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http://dx.doi.org/10.1089/apc.2018.0282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459270PMC

Microaggressions and Discrimination Relate to Barriers to Care Among Black Women Living with HIV.

AIDS Patient Care STDS 2019 Apr;33(4):175-183

1 Department of Psychology, University of Miami, Miami, Florida.

In the United States, black women living with HIV (BWLWH) represent the highest proportion of women living with HIV and dying from HIV-related illnesses when compared with women of other racial/ethnic groups. These disparities may be linked to social and structural factors faced by BWLWH, including race- and HIV-related discrimination, and gendered racial microaggressions (GRMs). GRMs are everyday insults that black women experience due to being both black and female (e. Read More

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http://dx.doi.org/10.1089/apc.2018.0258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459277PMC

Confluent paths: Research and community participation to protect the right to health among transgender women in Peru.

Glob Public Health 2019 Apr 1:1-9. Epub 2019 Apr 1.

a Center for Interdisciplinary Studies in Sexuality, AIDS and Society, Universidad Peruana Cayetano Heredia , Lima , Peru.

The recognition of transgender women (TGW) as the most vulnerable population to HIV/AIDS in Peru and their inclusion as a specific key affected population in health research was the outcome of an extended process that culminated when TGW community organisations succeeded in articulating themselves as a population separate from men who have sex with men (MSM) and, in alliance with some academic research groups, documented their HIV prevalence and vulnerability factors. Prior to that process, TGW remained subsumed under the epidemiological category of men who have sex with men (MSM), invisible in the context of public health policies. Based on a growing body of academic research evidence, coupled with the increasing number and capacities of TGW representatives in technical and policy-related gatherings, a consensus emerged for the establishment of TGW health statistics separate from MSM by 2010. Read More

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http://dx.doi.org/10.1080/17441692.2019.1599982DOI Listing

Gender, HIV-Related Stigma, and Health-Related Quality of Life Among Adults Enrolling in HIV Care in Tanzania.

AIDS Behav 2019 Mar 30. Epub 2019 Mar 30.

Department of Epidemiology, Columbia University, New York, NY, USA.

HIV-related stigma has been associated with worse health-related quality of life (HRQoL) among people living with HIV (PLWH). Little is known about how different types of HIV-related stigma (i.e. Read More

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http://dx.doi.org/10.1007/s10461-019-02480-1DOI Listing

New filovirus disease classification and nomenclature.

Nat Rev Microbiol 2019 May;17(5):261-263

World Health Organization Regional Office for Africa, Brazzaville, Democratic Republic of the Congo.

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http://dx.doi.org/10.1038/s41579-019-0187-4DOI Listing
May 2019
4 Reads
23.574 Impact Factor

What determines violence among female sex workers in an intimate partner relationship? Findings from North Karnataka, south India.

BMC Public Health 2019 Mar 29;19(1):350. Epub 2019 Mar 29.

Johns Hopkins University, 3400 N. Charles Street, Baltimore, MD, USA.

Background: Like other women in India, female sex workers (FSWs) frequently experience violence from their intimate partners (IPs)-a reality that increases their risk of acquiring HIV or other sexually transmitted infections. Less is known about the nature of these intimate relationships or what aspect of the relationship increases the risk of IP violence (IPV). We measured the prevalence and determinants of IPV on FSWs in the context of north Karnataka, India, characterized by high HIV-prevalence and extreme poverty. Read More

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http://dx.doi.org/10.1186/s12889-019-6673-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440026PMC

The Cost-effectiveness of HIV Pre-exposure Prophylaxis and HIV Testing Strategies in High-risk Groups in India.

Clin Infect Dis 2019 Mar 28. Epub 2019 Mar 28.

Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.

Background: The HIV epidemic in India is concentrated in 3.1M men who have sex with men (MSM) and 1.1M people who inject drugs (PWID), with mean incidence 0. Read More

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http://dx.doi.org/10.1093/cid/ciz249DOI Listing

Outcomes of patients lost to follow-up after antiretroviral therapy initiation in rural north-eastern South Africa.

Trop Med Int Health 2019 Mar 28. Epub 2019 Mar 28.

Department of Population Health, London School of Hygiene & Tropical Medicine, London, UK.

Objective: The vital status of patients lost to follow-up often remains unknown in antiretroviral therapy (ART) programmes in sub-Saharan Africa because medical records are no longer updated once the patient disengages from care. Thus, we aimed to assess the outcomes of patients lost to follow-up after ART initiation in north-eastern South Africa.

Methods: Using data from a rural area in north-eastern South Africa, we estimated the cumulative incidence of patient outcomes (i) after treatment initiation using clinical records, and (ii) after loss to follow-up (LTFU) using data from clients that have been individually linked to Agincourt Health and Demographic Surveillance System (AHDSS) database. Read More

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http://dx.doi.org/10.1111/tmi.13236DOI Listing

Physical Education Policies in US Schools: Differences by School Characteristics.

J Sch Health 2019 Mar 28. Epub 2019 Mar 28.

Children's Physical Activity Research Group, Children's Physical Activity Research Group, Department of Exercise Science, Division of Health Aspects of Physical Activity, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208.

Background: We assessed the extent to which schools in the United States implement physical education policies identified in SHAPE America's Essential Components of Physical Education document and how implementation of these policies varies by school characteristics.

Methods: School policy data were collected as part of the 2014 School Health Policies and Practices Study via computer-assisted personal interviews in a nationally representative sample of K-12 schools and were linked to extant data on school characteristics. Bivariate analyses and Poisson regression model were used to examine how physical education policies differed by school characteristics. Read More

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http://dx.doi.org/10.1111/josh.12762DOI Listing

Contribution of specific diseases and injuries to changes in health adjusted life expectancy in 187 countries from 1990 to 2013: retrospective observational study.

BMJ 2019 03 27;364:l969. Epub 2019 Mar 27.

Department of Health Policy and Administration, School of Public Health, Peking University, Beijing 100191, China

Objective: To quantify and compare the contribution of 306 diseases and injuries to the changes in health adjusted life expectancy at birth (HALE) between 1990 and 2013.

Design: Retrospective demographic analysis based on aggregated data and using life table technique, Sullivan method, and decomposition method for differences in health expectancy.

Setting: The globe, 21 regions, and 187 countries, covered in the Global Burden of Disease Study (GBD) 2013. Read More

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http://dx.doi.org/10.1136/bmj.l969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435998PMC

"Thoughts Can Kill You": Characterization of Mental Health Symptoms by Ugandan Grandparent-Caregivers in the HIV/AIDS Era.

Issues Ment Health Nurs 2019 Mar 27:1-8. Epub 2019 Mar 27.

a Department of Physiological Nursing, School of Nursing , University of California-San Francisco , San Francisco , California , USA.

Studies of caregiving provided to HIV/AIDS orphans by sub-Saharan African grandparents have found that it has physical, financial, and emotional consequences. Our study extended this research by identifying and characterizing the symptoms experienced by Ugandan grandparent- caregivers, particularly as related to the caregiving role, loss and grief. Grounded theory methodology was used to conduct and analyze audio-recorded, semi-structured interviews with 32 grandparents. Read More

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http://dx.doi.org/10.1080/01612840.2018.1553001DOI Listing

Immediate Motivators to Seeking Voluntary Medical Male Circumcision Among HIV-Negative Adult Men in an Urban Setting in Botswana.

AIDS Educ Prev 2019 Apr;31(2):136-151

Botswana International Training and Education Center for Health (I-TECH), Gaborone, Botswana.

Randomized trials have shown that voluntary medical male circumcision (VMMC) significantly reduces HIV acquisition risk in men. We sought to identify subpopulations of Botswanan men with high levels of VMMC uptake by comparing an observational cohort of men presenting for circumcision services at two high-volume clinics in Botswana's capital city, Gabo-rone, with a matched, population-based random sample of uncircumcised men. Among these high uptake VMMC subpopulations, we then examined the immediate factors that play a role in men's decision to seek VMMC services. Read More

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http://dx.doi.org/10.1521/aeap.2019.31.2.136DOI Listing

Designing an Individually Tailored Multilevel Intervention to Increase Engagement in HIV and Substance Use Treatment Among People Who Inject Drugs With HIV: HPTN 074.

AIDS Educ Prev 2019 Apr;31(2):95-110

Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

People who inject drugs (PWID) face barriers to engagement in antiretro-viral treatment (ART) and medication-assisted treatment (MAT). We detail the design, rapid preparation and adaptation, and systematic implementation of a flexible, individually tailored intervention for PWID in multiple settings: Indonesia, Ukraine, and Vietnam. HPTN 074 integrated systems navigation and counseling to facilitate entry and adherence to ART and MAT. Read More

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https://guilfordjournals.com/doi/10.1521/aeap.2019.31.2.95
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http://dx.doi.org/10.1521/aeap.2019.31.2.95DOI Listing
April 2019
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Is symptom prevalence and burden associated with HIV treatment status and disease stage among adult HIV outpatients in Kenya? A cross-sectional self-report study.

AIDS Care 2019 Mar 27:1-10. Epub 2019 Mar 27.

a Faculty of Nursing Midwifery and Palliative Care , King's College London, Cicely Saunders Institute of Palliative Care Policy and Rehabilitation , London , UK.

People with HIV experience a high prevalence and burden of physical and psychological symptoms throughout their disease trajectory. These have important public and clinical health implications. We aimed to measure: the seven-day period prevalence of symptoms, the most burdensome symptoms, and determine if self-reported symptom burden is associated with treatment status, clinical stage and physical performance. Read More

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http://dx.doi.org/10.1080/09540121.2019.1595514DOI Listing

Healthcare facility characteristics associated with achievement and maintenance of HIV viral suppression among persons newly diagnosed with HIV in New York City.

AIDS Care 2019 Mar 25:1-10. Epub 2019 Mar 25.

a Division of Disease Control , New York City Department of Health and Mental Hygiene , Long Island City , NY , USA.

Health care facility characteristics have been shown to influence intermediary health outcomes among persons with HIV, but few longitudinal studies of suppression have included these characteristics. We studied the association of these characteristics with the achievement and maintenance of HIV viral suppression among New York City (NYC) residents aged 13 years and older newly diagnosed with HIV between 2006 and 2012. The NYC HIV surveillance registry provided individual and facility data (N = 12,547 persons). Read More

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https://www.tandfonline.com/doi/full/10.1080/09540121.2019.1
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http://dx.doi.org/10.1080/09540121.2019.1595517DOI Listing
March 2019
3 Reads