217 results match your criteria AAPA News [Journal]


Recovering from COVID-19.

Authors:
Julia Piwowarski

JAAPA 2021 Dec;34(12)

Julia Piwowarski is a second-year student in the PA program at the University of Saint Joseph in West Hartford, Conn. She has served as the student academy representative of her student society, volunteers as a member of the university's academic integrity board, and is serving her second term on the student delegation to the AAPA House of Delegates. The author has disclosed no potential conflicts of interest, financial or otherwise.

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December 2021

Validation of crystal structure of 2-acetamidophenyl acetate: an experimental and theoretical study.

J Biomol Struct Dyn 2021 Oct 4:1-13. Epub 2021 Oct 4.

Department of Physics, PSG Institute of Technology and Applied Research, Coimbatore, Tamil Nadu, India.

In this present study, we have determined the crystal structure of 2-acetamidophenyl acetate (2-AAPA) commonly used as influenza neuraminidase inhibitor, to analyze the polymorphism. Molecular docking and molecular dynamics have been performed for the 2-AAPA-neuraminidase complex as the ester-derived benzoic group shows several biological properties. The X-ray diffraction studies confirmed that the 2-AAPA crystals are stabilized by N-H···O type of intermolecular interactions. Read More

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October 2021

Presence of anti-acetylated peptide antibodies (AAPA) in inflammatory arthritis and other rheumatic diseases suggests discriminative diagnostic capacity towards early rheumatoid arthritis.

Ther Adv Musculoskelet Dis 2021 23;13:1759720X211022533. Epub 2021 Jul 23.

Division of Rheumatology, Department of Internal Medicine 3, Medical University of Vienna, Vienna, Austria & Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria.

Aims: To determine the diagnostic value of anti-acetylated peptide antibodies (AAPA) in patients with rheumatoid arthritis (RA).

Methods: Three acetylated peptides (ac-lysine, ac-lysine.inv and ac-ornithine) derived from vimentin were employed to measure AAPA by enzyme-linked immunosorbent assay (ELISA) in sera of 120 patients with early RA (eRA), 195 patients with established RA (est RA), 99 healthy controls (HC), and 216 patients with other inflammatory rheumatic diseases. Read More

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Depression, burnout, and professional outcomes among PAs.

JAAPA 2021 Sep;34(9):35-41

Sarah R. Blackstone is the family medicine research manager at University of Virginia School of Medicine in Charlottesville, Va. At the time this article was written, she was an assistant professor in the Department of Health Sciences at James Madison University in Harrisonburg, Va. Aimee K. Johnson is an assistant professor in the Department of Health Sciences at James Madison University. Noël E. Smith is senior director of PA and industry research and analysis at the American Academy of PAs (AAPA) in Alexandria, Va. Timothy C. McCall is research director at the National Association of County and City Health Officials in Washington, D.C., and director of health sciences undergraduate courses at George Washington University in Washington, D.C. Whitney R. Simmons and Ashley W. Skelly are assistant professors in the PA program at James Madison University. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Objective: This study examined the effect of depression and burnout on PA professional fulfillment and medical errors.

Methods: Eight hundred eighty PAs completed an online survey containing the Professional Fulfillment Index, PHQ-2, GAD-7, and demographic questions. Two serial mediation models examined the relationship between depression, burnout, and professional outcomes. Read More

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September 2021

Reasons PAs leave their jobs.

JAAPA 2021 Aug;34(8):43-47

Harrison Reed practices critical care medicine at George Washington University Hospital in Washington, D.C., is an assistant professor in the PA program at George Washington University, and is a clinical editor for JAAPA. Kari Bernard is a child and adolescent psychiatry PA with Orion Behavioral Health Network in Eagle River, Ala. Noël Smith is research director at the American Academy of PAs in Alexandria, Va. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Purpose: Employee turnover is an important indicator that carries a heavy financial cost for healthcare organizations. Although previous research has highlighted some factors associated with turnover, the reasons physician assistants (PAs) leave their jobs are not fully understood. This study aimed to determine the most common reasons behind PA turnover. Read More

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Determining in which pre-arthritis stage HLA-shared epitope alleles and smoking exert their effect on the development of rheumatoid arthritis.

Ann Rheum Dis 2021 Jul 20. Epub 2021 Jul 20.

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

Objectives: The human leukocyte antigen-shared epitope (HLA-SE) alleles and smoking are the most prominent genetic and environmental risk factors for rheumatoid arthritis (RA). However, at which pre-arthritis stage (asymptomatic/symptomatic) they exert their effect is unknown. We aimed to determine whether HLA-SE and smoking are involved in the onset of autoantibody positivity, symptoms (clinically suspect arthralgia (CSA)) and/or progression to clinical arthritis. Read More

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Accelerated vegetation succession but no hydrological change in a boreal fen during 20 years of recent climate change.

Ecol Evol 2021 Jun 2;11(12):7602-7621. Epub 2021 May 2.

Department of Environmental and Biological Sciences University of Eastern Finland Joensuu Finland.

Northern mires (fens and bogs) have significant climate feedbacks and contribute to biodiversity, providing habitats to specialized biota. Many studies have found drying and degradation of bogs in response to climate change, while northern fens have received less attention. Rich fens are particularly important to biodiversity, but subject to global climate change, fen ecosystems may change via direct response of vegetation or indirectly by hydrological changes. Read More

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Retention and change in PAs' first years of employment.

JAAPA 2021 Jun;34(6):40-43

Alicia K. Quella is a clinical associate professor, and chair/program director of the PA program at Augsburg University in Minneapolis, Minn. Roderick S. Hooker is an adjunct professor of health policy at Northern Arizona University in Phoenix. John M. Zobitz is a professor of mathematics, statistics, and computer science at Augsburg University. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Objective: Employment analyses demonstrate that physician assistants (PAs) exhibit role flexibility in US medicine. The next step in understanding this labor-shifting observation is to know at what career stage it first occurs.

Methods: Using matriculate data linked to the American Academy of PAs (AAPA) census survey data, a longitudinal analysis of seven graduate cohorts revealed that one-third of PAs changed specialty roles at least once during their first decade of employment. Read More

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Using the Theoretical Domains Framework to Identify Barriers and Facilitators to Elder-Friendly Care Implementation Within a Multi-Site Academic Health Centre.

Worldviews Evid Based Nurs 2021 Oct 20;18(5):310-313. Epub 2021 May 20.

McGill University Health Centre (MUHC), Montréal, QC, Canada.

Background: Societal demographic shifts are occurring globally. Within Quebec, Canada, the percentage of adults over 65 (older adults) is predicted to increase from 19.3% to >25. Read More

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October 2021

PAs and domestic violence education.

JAAPA 2020 Dec;33(12)

Katherine M. Thompson practices in the ED and is the medical director for interpersonal violence in Bellevue, Wash., and is a forensic examiner and CEO and founder of IPV Educators, LLC. Noël E. Smith is senior director of PA and industry research and analysis at the American Academy of PAs (AAPA) in Alexandria, Va. Timothy C. McCall is associate director of surveys and analysis at AAPA.

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December 2020

AAPA promotes PA research through 2020 ePosters digital edition.

Authors:
Noël E Smith

JAAPA 2020 Dec;33(12)

Noël E. Smith is senior director of PA and industry research and analysis at the American Academy of PAs in Alexandria, Va.

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December 2020

A History of the American Association of Pathologists' Assistants: Creating an Organization, Winning Hearts and Minds, and Building an Invaluable Profession.

Acad Pathol 2020 Jan-Dec;7:2374289520975158. Epub 2020 Dec 8.

University of Calgary, Alberta Precision Laboratories, Alberta Children's Hospital, Calgary, Alberta, Canada.

Thomas D. Kinney and Duke University started the first formal university-based training program for pathologists' assistants in 1969. Over the next 2 years, 2 more university-based programs were established. Read More

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December 2020

Improved classification of rheumatoid arthritis with a score including anti-acetylated ornithine antibodies.

Sci Rep 2020 11 6;10(1):19263. Epub 2020 Nov 6.

Experimental and Observational Rheumatology and Rheumatology Unit, Instituto de Investigacion Sanitaria - Hospital Clínico Universitario de Santiago (IDIS), Travesia Choupana, sn., 15706, Santiago de Compostela, Spain.

The presence of rheumatoid factor (RF) or anti-cyclic citrullinated peptide (anti-CCP) autoantibodies contributes to the current rheumatoid arthritis (RA) classification criteria. These criteria involve stratification on antibody levels, which limits reproducibility, and underperform in the RA patients without RF and anti-CCP. Here, we have explored if two anti-acetylated peptide antibodies (AAPA), anti-acetylated lysine (AcLys) and anti-acetylated ornithine (AcOrn), could improve the performance of the current criteria. Read More

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November 2020

Reexamining the persisting wage gap between male and female PAs.

JAAPA 2020 Nov;33(11):38-42

Timothy C. McCall is associate director of surveys and analysis at the American Academy of PAs (AAPA) in Alexandria, Va., and director of health sciences undergraduate courses in the Department of Clinical Research and Leadership at George Washington University in Washington, D.C. Noël E. Smith is senior director of PA and industry research and analysis at AAPA. This study was supported by AAPA's research department. The authors have disclosed no other potential conflicts of interest, financial or otherwise.

Objective: To determine the magnitude of any difference in total compensation between male and female physician assistants (PAs) after controlling for personal and workplace factors related to compensation.

Methods: Using data from the 2019 AAPA Salary Survey, the authors conducted a sequential regression analysis to examine the relationship between a variety of personal and practice demographics and total compensation.

Results: After controlling for compensation-related factors, a wage gap between male and female PAs persisted: female PAs were paid almost $0. Read More

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November 2020

Report from the AAPA President, other reports, and in memoriam.

Am J Phys Anthropol 2021 01 18;174(1):151-178. Epub 2020 Sep 18.

Department of Anthropology, University of Tennessee-Knoxville, Knoxville, Tennessee, USA.

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January 2021

The 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guidelines on the Management of Blood Cholesterol in Diabetes.

Diabetes Care 2020 08;43(8):1673-1678

University of Texas Southwestern Medical Center, Dallas, TX.

The American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines recently published its 2018 recommendations on management of LDL cholesterol (LDL-C) in people with diabetes. For primary prevention, moderate-intensity statin therapy is recommended for those aged 40-75 years, with a preference for high-intensity statin treatment for older subjects and for those with higher estimated risk or risk-enhancing factors following a patient-clinician discussion. Statin therapy may be reasonable in adults <40 years or >75 years of age where there is less evidence for benefit. Read More

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Socioeconomic position and mental health care use before and after first redeemed antidepressant and time until subsequent contact to psychologist or psychiatrists: a nationwide Danish follow-up study.

Soc Psychiatry Psychiatr Epidemiol 2021 Mar 8;56(3):449-462. Epub 2020 Jul 8.

Section of General Practice and The Research Unit for General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Purpose: The purpose was to investigate inequalities in access to care among people with possible depression.

Method: In this nationwide register-based cohort study of 30,593 persons, we observed the association between socioeconomic position (SEP, education/income) and mental health care use (MHCU) four months before the date of first redeemed antidepressant (Index Date/ID) and 12 months afterwards-and time to contact to psychologist/psychiatrist (PP). Logistic, Poisson, and Cox regression models were used, adjusted for sex, age, cohabitation, and psychiatric comorbidity. Read More

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Melatonin restores neutrophil functions and prevents apoptosis amid dysfunctional glutathione redox system.

J Pineal Res 2020 Oct 18;69(3):e12676. Epub 2020 Aug 18.

Department of Studies in Biochemistry, University of Mysore, Mysore, India.

Melatonin is a chronobiotic hormone, which can regulate human diseases like cancer, atherosclerosis, respiratory disorders, and microbial infections by regulating redox system. Melatonin exhibits innate immunomodulation by communicating with immune system and influencing neutrophils to fight infections and inflammation. However, sustaining redox homeostasis and reactive oxygen species (ROS) generation in neutrophils are critical during chemotaxis, oxidative burst, phagocytosis, and neutrophil extracellular trap (NET) formation. Read More

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October 2020

Purification and characterization of Protein C activator from Venom.

Prep Biochem Biotechnol 2020 1;50(9):907-914. Epub 2020 Jun 1.

Department of Pathophysiology, Institute of Snake Venom, Wannan Medical College, Wuhu, China.

Protein C (PC) plays an important role in the balance of coagulation and anticoagulation. Thus, the detection of PC activity is diagnostically significant for patients with cardiovascular diseases. Presently, the key methods to detect PC activity are the chromogenic assay and activated partial thromboplastin time (APTT) test. Read More

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My strange but amazing year as president.

Authors:
David E Mittman

JAAPA 2020 Jun;33(6):9-10

David E. Mittman is president and chair of the board of the American Academy of PAs. He welcomes comments and concerns on this or any other topic at The author has disclosed no other potential conflicts of interest, financial or otherwise.

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The Federal Trade Commission and Consumer Protections for Mobile Health Apps.

J Law Med Ethics 2020 03;48(1_suppl):103-114

Jennifer K. Wagner, J.D., Ph.D., is an Assistant Professor in the Center for Translational Bioethics & Health Care Policy and the Associate Director of Bioethics Research at Geisinger (Danville, PA) as well as a solo practicing attorney. She earned her J.D. at the University of North Carolina (Chapel Hill, NC) and her Ph.D. in Anthropology at the Pennsylvania State University (University Park, PA) before completing post-doctoral research at Duke University (Durham, NC) and the University of Pennsylvania (Philadelphia, PA) and serving as an AAAS Congressional Fellow in Washington, D.C. She has served as chair of the ASHG Social Issues Committee, co-chair of the AAPA Ethics Committee, and a member of the PBA Cybersecurity and Data Privacy Committee.

The Federal Trade Commission (FTC) has an important role to play in the governmental oversight of mobile health apps, ensuring consumer protections from unfair and deceptive trade practices and curtailing anti-competitive methods. The FTC's consumer protection structure and authority is outlined before reviewing the recent FTC enforcement activities taken on behalf of consumers and against developers of mhealth apps. The article concludes with identification of some challenges for the FTC and modest recommendations for strengthening the consumer protections it provides. Read More

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Inspiring the Future of Physician Assistant Ultrasound Education: Lessons Learned From the Inaugural Yes, iScan Event.

J Physician Assist Educ 2020 Mar;31(1):28-32

Patrick Bafuma, PA-C, is the lead physician assistant in the Department of Emergency Medicine at Columbia Memorial Hospital, Hudson, New York.

Purpose: Point-of-care ultrasound (POCUS), despite its rapid integration into undergraduate medical education curriculum, remains underutilized among physician assistant (PA) programs, with a resultant training gap between PAs and their physician collaborators. Herein, we present the Yes, iScan Ultrasound event, piloted at the 2018 American Academy of PAs (AAPA) conference, as a means to generate PA student interest in, and introductory engagement with, the emerging clinical adjunct of POCUS.

Methods: Physician assistant students and instructors were recruited to voluntarily participate. Read More

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Direct Medicare payments for PAs.

Authors:
David E Mittman

JAAPA 2020 02;33(2):12

David E. Mittman is president and chair of the board of the American Academy of PAs. He welcomes comments and concerns on this or any other topic at The author has disclosed no other potential conflicts of interest, financial or otherwise.

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February 2020

The chaos of hypertension guidelines for chronic kidney disease patients.

Clin Kidney J 2019 Dec 28;12(6):771-777. Epub 2019 Sep 28.

IIS-Fundacion Jimenez Diaz, School of Medicine, Universidad Autonoma de Madrid, Madrid, Spain.

Three major guidelines deal with blood pressure thresholds and targets for antihypertensive drug therapy in chronic kidney disease (CKD) patients: the 2012 Kidney Disease: Improving Global Outcomes Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease; the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults; and the 2018 ESC/ESH Guidelines for the Management of Arterial Hypertension. However, a careful reading of the three guidelines leaves the practicing physician confused about the definition of CKD, how hypertension and secondary hypertension should be diagnosed in CKD patients and what the blood pressure thresholds, targets and compelling indications of antihypertensive drug therapy should be for this population. Current guidelines refer to different CKD populations and propose different definitions of hypertension, different thresholds to initiate antihypertensive therapy in CKD patients and different BP targets compelling antihypertensive drug use. Read More

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December 2019

PAs are a solution to the growing need for clinicians to treat an aging population.

JAAPA 2019 Dec;32(12):46-49

Benjamin J. Smith is director of didactic education and an assistant professor in the PA program at Florida State University in Tallahassee, Fla. He also serves on the audit committee of the American Academy of PAs (AAPA) and as a volunteer on AAPA's PA Research Team Initiative. Timothy C. McCall is associate director of surveys and analysis at AAPA in Alexandria, Va. Elaine M. Slaven is a data analyst experienced associate at Guidehouse in Washington D.C. Noël Smith is senior director of PA and industry research and analysis at AAPA. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Objective: To elucidate the types of patients cared for by physician assistants (PAs), specifically older adults and those with complex medical conditions.

Methods: A nationwide survey was sent to PAs asking about their practice demographics, including the complexity of their patients and the types of treatment they provide; 676 responded.

Results: Less than 2% of PAs specialize in geriatrics but 92. Read More

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December 2019

Let's keep the momentum going for optimal team practice: Become a champion for PAs.

Authors:
David E Mittman

JAAPA 2019 09;32(9):12-13

David E. Mittman is president and chair of the board of the American Academy of PAs and is editor-in-chief of Clinician1, an online community for PAs and NPs. He welcomes comments and concerns around this or any other topic at The author has disclosed no other potential conflicts of interest, financial or otherwise.

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September 2019

Spotlight from the American Society for Preventive Cardiology on Key Features of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guidelines on the Management of Blood Cholesterol.

Am J Cardiovasc Drugs 2020 Feb;20(1):1-9

Division of Cardiology, Johns Hopkins University, Baltimore, USA.

The 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol retains focus on recommendations for statin treatment in the original four statin-eligible groups [those with atherosclerotic cardiovascular disease (ASCVD), diabetes, low-density lipoprotein cholesterol (LDL-C) ≥ 190 mg/dL, and higher risk primary prevention] without the use of treatment initiation or target LDL-C levels from the earlier 2013 American College of Cardiology/American Heart Association (ACC/AHA) guideline, but has several new features. First, patients with primary prevention are divided into those who are at low (< 5%), borderline (5% to < 7.5%), intermediate (7. Read More

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February 2020

Did the ACC/AHA/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA cholesterol guidelines get apoB right?

J Clin Lipidol 2019 May - Jun;13(3):360-366

Division of Cardiology, Mike and Valeria Rosenbloom Centre for Cardiovascular Prevention, McGill University Health Centre, McGill University. Electronic address:

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