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Invest Ophthalmol Vis Sci 2019 Jan;60(1):98-106

Department of Ophthalmology, Medical School, University of Thessaly, Larissa, Greece.

Purpose: The purpose of this study was to prospectively investigate the association between retinopathy of prematurity (ROP) and ocular growth in premature infants during the earliest weeks of life.

Methods: Premature infants in the national ROP screening program were recruited and examined at 1- or 2-week intervals between 30 and 38 weeks of postmenstrual age. One hundred infants with gestational age (GA) between 24 and 35 weeks (30. Read More

Korean J Ophthalmol 2018 08;32(4):257-264

Department of Ophthalmology, HanGil Eye Hospital, Incheon, Korea.

Purpose: To evaluate the agreement between optical biometry with swept-source optical coherence tomography-based optical biometry (IOLMaster 700) and other devices.

Methods: A total of 137 eyes (78 patients) with cataracts were included in this retrospective study. Axial length (AL), anterior chamber depth (ACD), keratometry, and white-to-white (WTW) distance measured using IOLMaster 700 were compared with results for the following five different biometers: IOLMaster 500, A-scan, automated refractor, manual keratometry, and Galilei G4. Read More

PLoS One 2018 23;13(7):e0199157. Epub 2018 Jul 23.

Hamilton Glaucoma Center, Department of Ophthalmology, Shiley Eye Institute, University of California-San Diego, La Jolla, California, United States of America.

Purpose: To classify subjects with primary angle closure into clusters based on features from anterior segment optical coherence tomography (ASOCT) imaging and to explore how these clusters correspond to disease subtypes, including primary angle closure suspect (PACS), primary angle closure glaucoma(PACG), acute primary angle closure (APAC) and fellow eyes of APAC and reveal the factors that become more predominant in each subtype of angle closure.

Method: A cross-sectional study of 248 eyes of 198 subjects(88 PACS eyes, 53 PACG eyes, 54 APAC eyes and 53 fellow eyes of APAC) that underwent complete examination including gonioscopy, A-scan biometry, and ASOCT. An agglomerative hierarchical clustering method was used to classify eyes based on ASOCT parameters. Read More

Clin Ophthalmol 2018 23;12:973-980. Epub 2018 May 23.

Vitreoretinal Research Unit, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.

Purpose: We compared the accuracy of axial length (AL) measurement obtained by optical biometry with that obtained by acoustic biometry in eyes with rhegmatogenous retinal detachment (RRD).

Patients And Methods: This prospective descriptive analytic study measured the AL of eyes with RRD preoperatively and 3 months postoperatively using optical biometry (intraocular lens [IOL] master group) and acoustic biometry (immersion A-scan group). Preoperative and postoperative measurements were compared by paired -test. Read More

Exp Eye Res 2018 07 30;172:104-111. Epub 2018 Mar 30.

Section of Neurobiology of the Eye, Ophthalmic Research Institute, University of Tuebingen, Elfriede Aulhorn Strasse 7, 72076, Tuebingen, Germany. Electronic address:

Following a hypothesis raised by M. and J. Neitz, Seattle, we have tested whether the abundance and the ratio of Long wavelength-sensitive (L) to Middle wavelength-sensitive (M) cones may affect eye size and development of myopia in the chicken. Read More

J Glaucoma 2018 Jun;27(6):e110-e112

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Background: Crouzon syndrome is the most common form of craniosynostosis, and mutations in the fibroblast growth factor receptor 2 and 3 (FGFR2 and FGFR3) genes are implicated in its pathogenesis.

Observation: A 10-year-old female patient with Crouzon syndrome and congenital glaucoma treated with trabeculectomy and ocular hypotensive medications was examined. The patient had proptosis, exposure keratopathy, megalocornea, thin central corneal thickness, a shallow anterior chamber, mild anterior subcapsular cataract, and a cup-to-disc ratio of 0. Read More

Int J Ophthalmol 2018 18;11(2):274-278. Epub 2018 Feb 18.

Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.

Aim: To compare the peripapillary retinal nerve fiber layer (RNFL) thickness measured optical coherence tomography (OCT) between different groups of myopia severity and controls.

Methods: This was a prospective cross-sectional study. All subjects underwent a full ophthalmic examination, refraction, visual field analysis and A-scan biometry. Read More

J Ophthalmol 2017 31;2017:9164846. Epub 2017 Dec 31.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.

Background: Retinitis pigmentosa (RP) comprises a group of inherited disorders in which patients typically lose night vision in adolescence and then lose peripheral vision in young adulthood before eventually losing central vision later in life. A retrospective case-control study was performed to evaluate differences in ocular biometric parameters in primary angle-closure glaucoma (PACG) patients with and without concomitant RP to determine whether a relationship exists between PACG and RP.

Methods: We used ultrasound biomicroscopy (UBM) to measure anterior chamber depth (ACD). Read More

J Pak Med Assoc 2018 Jan;68(1):81-84

Liaquat National Hospital, Karachi.

Objective: To evaluate the accuracy of biometry in the post-op phase of cataract surgery.

Methods: This study was conducted at Liaquat National Hospital, Karachi, from June 2015 to July 2016, and comprised the audit of patients who underwent cataract surgery during the period. Keratometry was done on Haag-Strait manual keratometer and A-scan was done by applanation contact method on SonoMed machine. Read More

J Ophthalmol 2017 15;2017:6823965. Epub 2017 Oct 15.

The 2nd Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang 325027, China.

Purpose: To investigate the ocular parameters of premature infants without ROP at gestational age (GA) more than 28 weeks and their relationship with growth parameters.

Methods: 76 preterm infants without ROP and 65 term infants were involved to undergo portable slit lamp, RetCam3, ultrasonic A-scan biometry, and cycloplegic streak examination at their 40 weeks' postconceptional ages (PCA). Ocular parameters of infants' right eye and growth parameters were used for analysis. Read More

J Curr Glaucoma Pract 2017 Sep-Dec;11(3):86-91. Epub 2017 Oct 27.

Director Clinical Research, Department of Biostatistics, National Institute of Nutrition Hyderabad, Telangana, India.

Aim: To evaluate the configuration of the anterior chamber angle quantitatively and study the morphological changes in the eye with ultrasound biomicroscopy (UBM) in primary angle closure glaucoma (PACG) patients after laser peripheral iridotomy (LPI).

Materials And Methods: A total of 185 eyes of 185 PACG patients post-LPI and 126 eyes of 126 normal subjects were included in this prospective study. All subjects underwent complete ophthalmic evaluation, A-scan biometry, and UBM. Read More

Graefes Arch Clin Exp Ophthalmol 2017 Dec 3;255(12):2437-2442. Epub 2017 Oct 3.

Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan.

Purpose: To quantitatively assess the biometry of the ciliary body in normal human eyes using ultrasound biomicroscopy.

Methods: We evaluated 85 eyes of 85 normal subjects (35 men and 50 women), whose age ranged from 11 to 86 years (mean ± SD, 56.8 ± 20. Read More

J Cataract Refract Surg 2017 Jun;43(6):767-773

From the Singapore Eye Research Institute (Atalay, Nongpiur, Baskaran, Perera, Wong, Aung), the Duke-NUS Graduate Medical School (Nongpiur, Baskaran, Wong), the Yong Loo Lin School of Medicine (Aung), National University of Singapore, and the Singapore National Eye Centre (Perera, Wong, Quek, Aung), Singapore, Singapore. Electronic address:

Purpose: To evaluate the intraocular pressure (IOP) change and associated factors 6 months after phacoemulsification in eyes with primary angle-closure suspect (PACS) and eyes with primary angle closure (PAC) that had no medical therapy.

Setting: Singapore National Eye Center, Singapore, Singapore.

Design: Retrospective case series. Read More

PLoS One 2017 12;12(6):e0178113. Epub 2017 Jun 12.

Institute of Genomic Medicine, Università Cattolica Del Sacro Cuore, Fondazione Policlinico A. Gemelli, Rome, Italy.

Objective: To investigate whether miscarried embryo/fetal crown rump length (CRL) measurement may yield a practical application for predicting a conclusive result at the cytogenetic analysis of miscarriage tissue. Our study might help in improving the cytogenetic method, the results of which may be affected by maternal cell contamination (MCC). In particular, we aimed at establishing whether the miscarried embryo/fetal CRL measurement shows accuracy in predicting the possibility of MCC and the scan cut-off value useful to this purpose and, as a result, suggest a multi-step procedure for the genetic ascertainment. Read More

Korean J Ophthalmol 2017 Apr 21;31(2):165-171. Epub 2017 Mar 21.

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: The aim of this study was to investigate the differences in anterior segment ocular parameters in anisometropia >1 D.

Methods: This study included 202 eyes of 101 subjects ranging from 10 to 40 years of age with anisometropia of 1 D or more. The subjects were divided into groups according to anisomyopia, anisoastigmatism, and anisohypermetropia. Read More

J Cataract Refract Surg 2017 Jan;43(1):74-79

From the Cullen Eye Institute (B.V. Ventura, Wang, Koch, Weikert), Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA; Altino Ventura Foundation (B.V. Ventura, M.C. Ventura), HOPE Eye Hospital (B.V. Ventura, M.C. Ventura), Recife, and the Department of Ophthalmology (B.V. Ventura), Federal University of São Paulo, São Paulo, Brazil.

Purpose: To compare biometry measurements and intraocular lens (IOL) power calculations obtained by a new optical A-scan interferometer biometer (Galilei G6) (new biometer) and a partial coherence interferometer biometer (IOLMaster 500) (reference biometer).

Setting: Private practice, Recife, Brazil.

Design: Retrospective comparative study. Read More

Turk J Ophthalmol 2017 Jan 17;47(1):28-33. Epub 2017 Jan 17.

Çanakkale Onsekiz Mart University Faculty of Medicine, Department of Ophthalmology, Çanakkale, Turkey.

Objectives: To compare retinal and optic disc characteristics between amblyopic and non-amblyopic eyes in patients with myopic and hyperopic anisometropia measured with optical coherence tomography (OCT).

Materials And Methods: Patients with myopic (25 patients: 17 female, 8 male; median age 27 years, range 16-40 years) and hyperopic (31 patients: 19 female, 12 male; median age 20 years, range 13-41 years) anisometropic amblyopia were included. Eye examination included determination of best-corrected visual acuity (BCVA) with a Snellen chart, measurement of manifest and cycloplegic refraction after pupillary dilation, alternate cover testing, globe movement evaluation, A-scan biometry for axial length, biomicroscopy, fundus examination, and OCT scanning. Read More

J Nucl Med 2017 07 19;58(7):1104-1110. Epub 2017 Jan 19.

Molecular Nutritional Medicine, ZIEL-Institute for Food & Health, Technical University of Munich, Freising, Germany; and.

Brown adipose tissue (BAT) provides a means of nonshivering thermogenesis. In humans, active BAT can be visualized by F-FDG uptake as detected by PET combined with CT. The retrospective analysis of clinical scans is a valuable source to identify anthropometric parameters that influence BAT mass and activity and thus the potential efficacy of envisioned drugs targeting this tissue to treat metabolic disease. Read More

Bone 2017 04 27;97:43-48. Epub 2016 Dec 27.

Department of Radiology, Cumming School of Medicine, University of Calgary, Canada; McCaig Institute for Bone and Joint Health, University of Calgary, Canada. Electronic address:

Objective: High-resolution peripheral quantitative computed tomography (HR-pQCT) is a novel imaging modality capable of visualizing bone microarchitecture in vivo at human peripheral sites such as the distal radius and distal tibia. This research has extended the technology to provide a non-invasive assessment of bone microarchitecture at the human knee by establishing new hardware, imaging protocols and data analysis.

Design: A custom leg holder was developed to stabilize a human knee centrally within a second generation HR-pQCT field of view. Read More

Eye Contact Lens 2018 Sep;44 Suppl 1:S115-S117

Department of Ophthalmology (R.A., S.K.E.), Istanbul Medipol University, Istanbul, Turkey; Department of Ophthalmology (K.S.C.), Istanbul Bagcilar Training and Research Hospital, Istanbul, Turkey; Department of Ophthalmology (E.K.), Bati Göz Hospital, Izmir, Turkey; and Department of Ophthalmology (S.K.), Dokuz Eylul University, Izmir, Turkey.

Purpose: To compare anterior chamber depth (ACD), axial length (AL), and lens thickness (LT) measurements obtained by the Lenstar LS 900 (Haag-Streit AG) optical low-coherence reflectometry with those obtained by the A-scan contact ultrasound among patients with moderate and high hypermetropia.

Methods: Fifty-two eyes of 52 patients with moderate and high hypermetropia (spherical equivalent of +4 D or more) were examined in this study measurements of ACD, AL, and LT obtained by Lenstar were compared with those obtained by applanation A-scan ultrasound. All measurements were obtained by two independent examiners. Read More

J Curr Ophthalmol 2016 Dec 12;28(4):170-175. Epub 2016 Jul 12.

Koret Vision Center, University of California, San Francisco Medical School, San Francisco, CA, USA.

Purpose: To evaluate different mechanisms of primary angle closure (PAC) and to quantify anterior chamber (AC) parameters in different subtypes of angle closure disease using anterior segment optical coherence tomography (AS-OCT).

Methods: In this prospective study, 115 eyes of 115 patients with angle closure disease were included and categorized into three groups: 1) fellow eyes of acute angle closure (AAC; 40 eyes); 2) primary angle closure glaucoma (PACG; 39 eyes); and 3) primary angle closure suspect (PACS; 36 eyes). Complete ophthalmic examination including gonioscopy, A-scan biometry, and AS-OCT were performed. Read More

J Glaucoma 2017 Feb;26(2):153-158

*Koret Vision Center, San Francisco Medical School, University of California, San Francisco, CA †Farabi Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran ‡Departments of Ophthalmology, University of Melbourne, Melbourne, Vic., Australia.

Purpose: To quantitatively analyze the anterior chamber parameters in patients with pupillary block (PB) and plateau iris configuration (PIC) using anterior segment optical coherence tomography (ASOCT).

Patients And Methods: In this cross-sectional study, nonglaucomatous subjects consecutively recruited and a total of 212 eyes divided into 3 groups of PIC (31 eyes), PB (60 eyes), and open angles (121 eyes) based on gonioscopic and ultrasound biomicroscopy findings. All patients underwent ASOCT imaging and A-scan biometry of both eyes. Read More

Int J Ophthalmol 2016 18;9(10):1521-1523. Epub 2016 Oct 18.

2nd Department of Ophthalmology, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki 56429, Greece.

Invest Ophthalmol Vis Sci 2016 Oct;57(13):5320-5325

Singapore Eye Research Institute, Singapore 3Singapore National Eye Centre, Singapore 4Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Purpose: To compare ocular biometric and anterior segment parameters between the affected and fellow eye in subjects with acute primary angle closure (APAC).

Methods: We evaluated 76 subjects with unilateral APAC who had undergone bilateral laser peripheral iridotomy before enrollment. Imaging was done using anterior segment optical coherence tomography and a customized software was used to measure the following: angle opening distance (AOD750); trabecular-iris space area (TISA750); iris thickness (IT750); iris curvature (ICURV); iris area (IAREA); anterior chamber depth; area and volume (ACD; ACA and ACV); anterior chamber width (ACW); anterior vault (ACD+LV); lens vault (LV); and pupil diameter (PD). Read More

Int Ophthalmol 2017 Aug 13;37(4):849-858. Epub 2016 Sep 13.

Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirappalli, 620001, Tamil Nadu, India.

Purpose: To compare data on anatomical and biometric parameters, and their combination, obtained by using ultrasound biomicroscopy (UBM) and A-scan in eyes with phacomorphic glaucoma (PG) and eyes with mature cataract and to determine differences that may predispose to development of PG.

Methods: Eighty patients (80 eyes) were enrolled in this cross-sectional study. Anterior chamber parameters, namely anterior chamber depth (ACD), angle-opening distance (AOD), iris-lens contact distance (ILCD), and trabecular-ciliary process distance (TCPD), among other parameters, were assessed by UBM (35 MHz), while axial length (AL) and lenticular thickness (LT) were determined by A-scan biometry. Read More

BMC Ophthalmol 2016 Jul 8;16:96. Epub 2016 Jul 8.

Department of Ophthalmology, Istanbul Medipol University, Esenler Hospital, Birlik Mah., Bahceler Cad., Number 5, Esenler, Istanbul, 34230, Turkey.

Background: The SRK/T formula is one of the third generation IOL calculation formulas. The purpose of this study was to evaluate the performance of the SRK/T formula in predicting a target refraction ±1.0D in short and long eyes using ultrasound biometry after phacoemulsification. Read More

Int J Ophthalmol 2016 18;9(6):876-80. Epub 2016 Jun 18.

Department of Ophthalmology, the Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China.

Aim: To compare the axial lengths (ALs) measured with Lenstar, IOLMaster and A-scan contact ultrasound (Ultrasound) in normal and high myopia (HM).

Methods: Eighty-four normal eyes and 49 HM eyes were included. Three consecutive measurements were performed on each eye in the following order: Lenstar, IOLMaster, and Ultrasound. Read More

BMC Ophthalmol 2016 Jun 7;16:78. Epub 2016 Jun 7.

International Centre for Eye Health (ICEH), Department of Clinical Research, London School of Hygiene & Tropical Medicine (LSHTM), Keppel Street, London, WC1E 7HT, UK.

Background: The glaucoma-specific blindness prevalence in Nigeria (0.7 %, 95 % CI 0.6-0. Read More

J Curr Ophthalmol 2015 Sep-Dec;27(3-4):110-4. Epub 2016 Feb 9.

Department of Ophthalmology, University of Ilorin Teaching Hospital, Nigeria.

Purpose: The study compared ocular biometry values using applanation and immersion techniques to determine the most applicable method for our tertiary training centre where personnel with different levels of experience and expertise in biometry take measurements used in calculation of required intraocular lens before cataract surgery.

Methods: The study was a prospective cross-sectional comparative study of different techniques of ocular biometry from diagnostic equipment (biometry probe 10 MHz Sonomed(®) A-scan (PACSCAN 300A, USA). Measurement variables were obtained among children and adults undergoing cataract surgery. Read More

Nat Genet 2016 07 16;48(7):709-17. Epub 2016 May 16.

23andMe, Inc., Mountain View, California, USA.

We performed a scan for genetic variants associated with multiple phenotypes by comparing large genome-wide association studies (GWAS) of 42 traits or diseases. We identified 341 loci (at a false discovery rate of 10%) associated with multiple traits. Several loci are associated with multiple phenotypes; for example, a nonsynonymous variant in the zinc transporter SLC39A8 influences seven of the traits, including risk of schizophrenia (rs13107325: log-transformed odds ratio (log OR) = 0. Read More

Optom Vis Sci 2016 07;93(7):692-704

*PhD The College of Optometry, University of Houston, Houston, Texas (all authors).

Purpose: Previous ultrasound biomicroscopy (UBM) studies showed that accommodative optical response (AOR) can be predicted from accommodative biometric changes in a young and a pre-presbyopic population from linear relationships between accommodative optical and biometric changes, with a standard deviation of less than 0.55D. Here, paraxial schematic eyes (SE) were constructed from measured accommodative ocular biometry parameters to see if predictions are improved. Read More

Can J Ophthalmol 2016 Apr;51(2):108-12

Ophthalmology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Objective: To assess the accuracy of axial length measurements in cases of macula-off retinal detachment using different methods (optical biometry, A-scan ultrasound, and combined applanation vector-A/B-scan biometry).

Methods: This prospective clinical study included 100 eyes of 100 patients who underwent vitrectomy alone or phacovitrectomy for macula-off retinal detachment. All patients included signed an informed consent. Read More

Optom Vis Sci 2016 07;93(7):683-91

*OD, MS †OD, PhD ‡OD Department of Optometry and Visual Science, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana (NYK, AOA, PBA, EA, KB); Department of Psychological Sciences, Vanderbilt University, Nashville, TN (CO-B).

Purpose: To determine the relationship between accommodative lag and rate of myopia progression when Ghanaian myopic school children are either undercorrected or fully corrected with single vision lenses.

Methods: A 2-year single masked randomized control trial was conducted using 150 Ghanaian myopic children aged 10 to 15 years with mean baseline myopia of -1.98 ± 0. Read More

J Cataract Refract Surg 2016 Jan;42(1):62-7

From Stein Eye Institute (Hoffer), University of California, Los Angeles; St. Mary's Eye Center (Hoffer), Santa Monica, California; Keck School of Medicine (Shammas), Los Angeles, and; Shammas Eye Medical Center (Shammas), Lynwood, California, USA; G.B. Bietti Foundation IRCCS (Savini), Rome, Italy; School of Ophthalmology and Eye Hospital (Huang), Wenzhou Medical University, Wenzhou, China.

Purpose: To evaluate the agreement between the measurements provided by a new optical biometer, the Aladdin, based on optical low-coherence interferometry (OLCI), and those provided by the most commonly used optical biometer (IOLMaster 500), based on partial-coherence interferometry (PCI).

Setting: Multicenter clinical trial.

Design: Prospective evaluation of diagnostic test. Read More

Int Ophthalmol 2016 Oct 8;36(5):707-12. Epub 2016 Feb 8.

Department of Ophthalmology, Dumlupinar University School of Medicine, Kutahya, 43270, Turkey.

The purpose of the study was to compare the accuracy of various biometric formulas for predicting postoperative refraction determined using applanation A-scan ultrasound. This retrospective comparative study included 485 eyes that underwent uneventful phacoemulsification with intraocular lens (IOL) implantation. Applanation A-scan ultrasound biometry and postoperative manifest refraction were obtained in all eyes. Read More

Vestn Oftalmol 2015 Sep-Oct;131(5):26-31

Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021.

Aim: to evaluate the accuracy of different modified methods for axial length (AL) measurement in silicone-filled eyes.

Material And Methods: The study was conducted in a group of 60 patients (60 eyes) with silicone oil tamponade (Oxane 1300 cst). Axial length measurements were taken using IOL Master optical coherence biometry ('silicone-filled eye' mode) and modified A-scan ultrasound biometry (velocity of ultrasound passing through the vitreous body set at 980 m/s and 1000 m/s). Read More

Arch Gynecol Obstet 2016 09 7;294(3):487-93. Epub 2016 Jan 7.

Department of Obstetrics and Gynecology, Erlangen University Hospital, Universitätsstrasse 21-23, 91054, Erlangen, Germany.

Introduction: To evaluate the influence of the time interval between examination and delivery on the accuracy of sonographic fetal weight estimation (WE).

Materials And Methods: 8723 singleton pregnancies were included in this retrospective cohort study. Fetuses were divided into eight groups with regard to the time interval between estimation and delivery (group 1: 0 days; group 2: 1-3 days; group 3: 4-7 days; group 4: 8-14 days; group 5: 15-21 days; group 6: 22-28 days; group 7: 29-35 days; group 8: 36-42 days). Read More

Int J Ophthalmol 2015 18;8(6):1151-5. Epub 2015 Dec 18.

Koret Vision Center, San Francisco Medical School, University of California, San Francisco, CA 94143, USA.

Aim: To assess lens thickness measurements with anterior segment-optical coherence tomography (AS-OCT) in comparison with A-scan ultrasonography (A-scan US).

Methods: There were 218 adult subjects (218 eyes) aged 59.2±9. Read More

Indian J Ophthalmol 2015 Oct;63(10):763-6

Department of Glaucoma, Clinical Research Center, Institution of Drug Clinical Trials, Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, 54S.Xianlie Road, Guangzhou 510060, People's Republic of China.

Purpose: The aim of the present study was to evaluate the effect of surgical peripheral iridectomy (SPI) on choroidal thickness in primary angle-closure suspect (PACS) eyes.

Materials And Methods: This was a prospective observational case series of 30 subjects with PACS. Ocular biometry was performed before SPI (baseline) and then 1 week later. Read More

BMC Ophthalmol 2015 Dec 12;15:176. Epub 2015 Dec 12.

International Centre for Eye Health (ICEH), Clinical Research Department, London School of Hygiene and Tropical Medicine (LSHTM), Keppel Street, London, WC1E 7HT, UK.

Background: Glaucoma is the leading cause of irreversible blindness worldwide. There tends to be a lower reporting of glaucoma in Africa compared to other blinding conditions in global burden data. Research findings of glaucoma in Nigeria will significantly increase our understanding of glaucoma in Nigeria, in people of the West African diaspora and similar population groups. Read More

Int Ophthalmol 2016 Apr 8;36(2):267-71. Epub 2015 Dec 8.

Thalassemia Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

The aim of this study is to determine and compare biometric and refractive characteristics of thalassemia major patients and normal individuals. In this cross-sectional study, 54 thalassemia major patients were selected randomly as case group, and 54 age- and sex-matched healthy subjects were regarded as control group. Refractive errors, corneal curvature and ocular components were measured by autokeratorefractometery and A-scan ultrasonography, respectively. Read More

Invest Ophthalmol Vis Sci 2015 Dec;56(13):7611-7

Koret Vision Center, University of California, San Francisco Medical School, San Francisco, California, United States.

Purpose: The purpose of this study is to compare anterior segment-optical coherence tomography (AS-OCT) parameters in phacomorphic angle closure and acute primary angle closure (APAC) eyes.

Methods: In this cross-sectional case series, a total of 134 patients with phacomorphic angle closure (28 eyes) or APAC (54 eyes), as well as normal control subjects (52 eyes), were enrolled. Patients underwent AS-OCT imaging and A-scan biometry of both eyes. Read More

Eye (Lond) 2016 Mar 20;30(3):400-5. Epub 2015 Nov 20.

Department of Ophthalmology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, Korea.

Purpose: To determine the biometric and refractive changes after orbital decompression in Korean patients with thyroid-associated orbitopathy (TAO).

Methods: Retrospective, observational study (between October 2012 and September 2014) was performed. Patients with TAO undergoing orbital decompression for stable proptosis received ophthalmic examinations, including Hertel exophthalmometry, A-scan biometry, autorefraction measures, corneal topography, and wavefront aberration measures, before orbital decompression and again 2 months after surgery. Read More

Optom Vis Sci 2016 Feb;93(2):136-40

*MSc †MD ‡PhD Ophthalmic Epidemiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran (AA, MP, HE, SY, EG); and Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran (MY).

Purpose: To compare biometric changes measured with contact and noncontact methods after mitomycin-C-augmented trabeculectomy.

Methods: In this prospective study, 31 eyes from 31 glaucoma patients scheduled for primary trabeculectomy were enrolled. Biometric parameters including axial length (AL), anterior chamber depth (ACD), and lens thickness (LT) were measured using contact ultrasound biometry (UD-6000 Ultrasonic A/B scanner biometer; Tomey Corporation, Nagoya, Japan) and a noncontact optical biometry device (Lenstar; Haag-Streit AG, Koeniz, Switzerland). Read More

Invest Ophthalmol Vis Sci 2015 Aug;56(9):5650-5

Singapore Eye Research Institute, Singapore 3Singapore National Eye Centre, Singapore 4Duke NUS Graduate Medical School, Singapore.

Purpose: To analyze changes in refraction and associated biometric changes in atropine- and placebo-treated eyes in the Atropine for Treatment of Myopia study (ATOM1).

Methods: A total of 400 myopic children, aged 6 to 12 years, were assigned randomly to receive 1% atropine or a placebo agent in one eye daily for 2 years, after which drops were stopped and children monitored for another year. Cycloplegic autorefraction, A-scan biometry, and automated keratometry were performed at the initial visit, 2 weeks (baseline), and at 4, 8, 12, 16, 20, 24, 30, and 36 months. Read More

Arq Bras Oftalmol 2015 May-Jun;78(3):146-9

Ophthalmology Department, Kastamonu Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Purpose: To analyze ocular biometry parameters and evaluate their relationship with gestational age, birth weight, and postmenstrual age in prematurely born infants.

Methods: The right eyes of 361 premature infants born before the 36th gestational week were evaluated. Birth weight, gestational week, and gender were recorded. Read More

Clin Ophthalmol 2015 29;9:1159-63. Epub 2015 Jun 29.

Mizoguchi Eye Clinic, Nagasaki, Japan ; Nishigaki Eye Clinic, Nagoya, Japan.

Purpose: To determine the prevalence of plateau iris in Japanese patients with primary angle closure (PAC) and primary angle closure glaucoma (PACG) and analyze the biometric parameters in patients with plateau iris using ultrasound biomicroscopy (UBM).

Methods: In this cross-sectional observational study, subjects aged >50 years with PAC and PACG who had previously undergone a patent laser peripheral iridotomy underwent UBM in one eye. UBM images were qualitatively analyzed using standardized criteria. Read More

Int Ophthalmol 2016 Apr 27;36(2):179-83. Epub 2015 Jun 27.

Department of Ophthalmology, Faculty of Medicine, Ondokuz Mayıs University, 55139, Samsun, Turkey.

The purpose of this study was to investigate the effects of pupil dilation on the parameters of the AL-Scan (Nidek Co., Ltd, Gamagori, Japan). We compared the measurements of axial length (AL), anterior chamber depth (ACD), central corneal keratometry reading, pupil diameter, and intraocular lens (IOL) power of 72 eyes of 72 healthy volunteers and patients scheduled for cataract surgery before and 45 min after instillation of cyclopentolate hydrochloride 1 % using the AL-Scan. Read More

J Clin Diagn Res 2015 Mar 1;9(3):NC01-4. Epub 2015 Mar 1.

Professor and Head of the Department, Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sribalaji Vidyapeeth University , Pondicherry, India .

Purpose: To evaluate the foveal and macular thickness in various degrees of myopia and its association with axial length in low, moderate and high degrees of myopia.

Design: A cross-sectional study was done in the Department of Ophthalmology, MGMCRI, Pondicherry, India.

Materials And Methods: One hundred and twenty five eyes eyes of 64 myopic subjects between the age group of 20-40 who fulfilled the inclusion criteria were selected and complete ophthalmic examination was done. Read More

Curr Eye Res 2016 04 5;41(4):485-91. Epub 2015 May 5.

a Peking University Third Hospital, Peking University Eye Center, Key Laboratory of Vision Loss and Restoration, Ministry of Education , Beijing , China .

Purpose: To compare the ciliary body morphology between the Caucasians and Chinese, and to determine the associated anterior segment parameters.

Methods: The study groups were comprised of four age- and gender-matched cohorts: American Caucasians, American Chinese, southern and northern mainland Chinese. Ultrasound biomicroscopy (UBM) was performed to assess the following measurements of the ciliary body: trabecular-ciliary process distance (TCPD), trabecular-ciliary process angle (TCA) and ciliary body thickness at 1 mm posterior to the scleral spur (CBT1). Read More