129,526 results match your criteria 76] years


Am J Med 2022 Jan 23. Epub 2022 Jan 23.

Houston Methodist Debakey Heart & Vascular Center, Houston, TX, USA. Electronic address:

Background: We aimed to compare the added prognostic value of plaque burden to cardiac computed tomographic angiography (CCTA) anatomic assessment and single photon emission computed tomography (SPECT) physiologic assessment in patients with diabetes undergoing both tests.

Methods: Consecutive patients with diabetes who underwent clinically indicated CCTA and SPECT myocardial imaging for suspected coronary artery disease were included. Stenosis severity and segment involvement score (SIS) were determined from CCTA, and presence of ischemia was determined from SPECT. Read More

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January 2022

A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001-2016.

PLoS One 2022 26;17(1):e0262228. Epub 2022 Jan 26.

School of Sport Sciences, UiT The Arctic University of Norway, Tromsø, Norway.

Aims: The aim was to investigate the long-term association between leisure time physical activity and hip areal bone mineral density (aBMD), in addition to change in hip aBMD over time, in 32-86 years old women and men.

Methods: Data were retrieved from the 2001, 2007-2008, and 2015-2016 surveys of the Tromsø Study, a longitudinal population study in Norway. Leisure time physical activity was assessed by the four-level Saltin-Grimby Physical Activity Level Scale which refers to physical exertion in the past twelve months. Read More

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January 2022

Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study.

PLoS One 2022 26;17(1):e0260538. Epub 2022 Jan 26.

Clinical Science and Services, The Royal Veterinary College, Hatfield, Herts, United Kingdom.

Background: Prolapsed nictitating membrane gland (PNMG) is the most common disorder of the third eyelid in dogs. However, the epidemiology of PNMG in the wider dog population remains understudied.

Methods: Using de-identified clinical data from the VetCompass Programme, this cohort study aimed to report the prevalence, demographic and breed-related risk factors of PNMG in dogs attending UK primary care veterinary practices in 2016. Read More

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January 2022

Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults.

Cochrane Database Syst Rev 2022 Jan 26;1:CD000093. Epub 2022 Jan 26.

Bone and Joint Health, Blizard Institute, Queen Mary University of London, London, UK.

Background: Hip fractures are a major healthcare problem, presenting a substantial challenge and burden to patients, healthcare systems and society. The increased proportion of older adults in the world population means that the absolute number of hip fractures is rising rapidly across the globe. Most hip fractures are treated surgically. Read More

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January 2022

Incidence and Outcomes of Nontraumatic Shock in Adults Using Emergency Medical Services in Victoria, Australia.

JAMA Netw Open 2022 Jan 4;5(1):e2145179. Epub 2022 Jan 4.

Department of Cardiology, Alfred Health, Melbourne, Victoria, Australia.

Importance: Nontraumatic shock is a challenging clinical condition, presenting urgent and unique demands in the prehospital setting. There is a paucity of data assessing its incidence, etiology, and clinical outcomes.

Objective: To assess the incidence, etiology, and clinical outcomes of patients treated by emergency medical services (EMS) with nontraumatic shock using a large population-based sample. Read More

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January 2022

Skin Cancer Risk Factors and Screening Among Asian American Individuals.

JAMA Dermatol 2022 Jan 26. Epub 2022 Jan 26.

Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.

Importance: Asian American individuals are the fastest growing racial group in the US but remain underrepresented in health disparities research, including research on skin cancer risk factors and screening. Improved understanding of preventable skin cancer risk factors and screening may demonstrate unmet needs among Asian American individuals.

Objective: To examine sunburns, sun-protective behaviors, indoor tanning, and total body skin examinations (TBSEs) for skin cancer screening among Asian American subgroups compared with non-Hispanic White individuals. Read More

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January 2022

Lung-RADS Category 3 and 4 Nodules on Lung Cancer Screening in Clinical Practice.

AJR Am J Roentgenol 2022 Jan 26. Epub 2022 Jan 26.

Division of Thoracic Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Boston, MA.

Lung-RADS category 3 and 4 nodules account for most cancers among screening-detected lung cancers and are considered actionable nodules with management implications. The cancer frequency among such nodules is estimated in the Lung-RADS recommendations and has been investigated primarily using retrospectively assigned Lung-RADS classifications. To assess the frequency of cancer among lung nodules assigned Lung-RADS category 3 or 4 at lung cancer screening (LCS) in clinical practice and factors that impact the cancer frequency within each category. Read More

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January 2022

4S-AF scheme and ABC pathway guided management improves outcomes in atrial fibrillation patients.

Eur J Clin Invest 2022 Jan 26:e13751. Epub 2022 Jan 26.

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom.

Background: The 4S-AF scheme and the ABC pathway for integrated care have been proposed to better characterize and treat patients with atrial fibrillation (AF). We aimed to evaluate the assessment of the 4S-AF scheme and ABC pathway in Chinese AF patients.

Methods: The ChiOTEAF is a prospective, observational, multicenter registry. Read More

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January 2022

Foot orthoses for treating paediatric flat feet.

Cochrane Database Syst Rev 2022 Jan 26;1:CD006311. Epub 2022 Jan 26.

School of Health Sciences, Faculty of Health and Medicine, The University of Newcastle, Ourimbah, Australia.

Background: Paediatric flat feet are a common presentation in primary care; reported prevalence approximates 15%. A minority of flat feet can hurt and limit gait. There is no optimal strategy, nor consensus, for using foot orthoses (FOs) to treat paediatric flat feet. Read More

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January 2022

The management and outcome of hyponatraemia following transsphenoidal surgery: a retrospective observational study.

Acta Neurochir (Wien) 2022 Jan 25. Epub 2022 Jan 25.

Department of Endocrinology, University College London Hospital, London, UK.

Purpose: Hyponatraemia is a common complication following transsphenoidal surgery. However, there is sparse data on its optimal management and impact on clinical outcomes. The aim of this study was to evaluate the management and outcome of hyponatraemia following transsphenoidal surgery. Read More

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January 2022

Perioperative stroke and survival in coronary artery bypass grafting patients: a SWEDEHEART study.

Eur J Cardiothorac Surg 2022 Jan 25. Epub 2022 Jan 25.

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Objectives: Perioperative stroke is a severe complication of cardiac surgery. We assessed the incidence of stroke over time, the association between stroke and mortality and identified preoperative factors independently associated with perioperative stroke, in a large nationwide cardiac surgery population.

Methods: All patients who underwent coronary artery bypass grafting in Sweden 2006-2017 were included in a registry-based observational cohort study based on prospectively collected data. Read More

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January 2022

The Impact of the First COVID-19 Wave on European Vascular Education.

EJVES Vasc Forum 2022 Jan 21. Epub 2022 Jan 21.

Vascular Surgery Unit - Department of Experimental, Diagnostic and Specialty Medicine (DIMES) - University of Bologna "Alma Mater Studiorum", Bologna, Italy.

Introduction: Public health was severely affected by the first wave of the COVID-19 pandemic, imposing major daily life changes across the world, including health services that had to restructure significantly.

Report: Considering the potential side effects to the quality of vascular training, a digital survey (Survey Monkey®) was developed and submitted to vascular trainees from 7 July to 20 September 2020 through European mailing lists and social media platforms. The aim was to evaluate the standpoint of vascular education across Europe during the first wave of the COVID-19 pandemic and to identify possible measures to mitigate the negative effects to vascular trainees. Read More

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January 2022

Dengue Management in Triage using Ultrasound in children from Cambodia: a prospective cohort study.

Lancet Reg Health West Pac 2022 Feb 15;19:100371. Epub 2022 Jan 15.

University of Massachusetts Medical School.

Background: Dengue is a mosquito-borne viral infection with increasing global prevalence. It is endemic in more than 100 countries, with a heavy burden in Asia. Ultrasound findings including gallbladder wall thickening, ascites, and pleural effusions secondary to plasma leakage have been described in dengue. Read More

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February 2022

Machine learning for predicting readmission risk among the frail: Explainable AI for healthcare.

Patterns (N Y) 2022 Jan 3;3(1):100395. Epub 2021 Dec 3.

Informatics and Analytics, University of North Carolina at Greensboro, 500 Forest Building, Greensboro 27403, NC, USA.

Healthcare costs due to unplanned readmissions are high and negatively affect health and wellness of patients. Hospital readmission is an undesirable outcome for elderly patients. Here, we present readmission risk prediction using five machine learning approaches for predicting 30-day unplanned readmission for elderly patients (age ≥ 50 years). Read More

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January 2022

Evaluation of exposure to secondhand smoke and serum level of interleukin 18 in non-smokers.

Ann Med Surg (Lond) 2022 Jan 3;73:103238. Epub 2022 Jan 3.

Nutritional Health Research Center, School of Pharmacy, Lorestan University of Medical Sciences, Khorramabad, Iran.

Objective: Smoking is one significant global health care problems, that not only affects the users but also endangers the health of people inhaling the smoke (passive smoking/secondhand smoke). The serum level of IL-18, an important regulator of inherent and acquired immune response, is affected by cigarette smoking. The aim of this study was to evaluate the effect of secondhand smoke (SHS) exposure on IL-18 serum level in non-smoker adults. Read More

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January 2022

Practices of vitamin D supplementation leading to vitamin D toxicity: Experience from a Low-Middle Income Country.

Ann Med Surg (Lond) 2022 Jan 5;73:103227. Epub 2022 Jan 5.

Department of Pathology and Laboratory Medicine, Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan.

Introduction: The trend of prescribing VD preparations for nonspecific body aches and self-medication has increased significantly. The importance of vitamin D toxicity (VDT) has been underestimated and under recognized. This study was done to determine the frequency toxicity (>150 ng/ml) in subjects for 25-hydroxyvitamin D (25OHD) and evaluate the vitamin D (VD) supplements used by these subjects. Read More

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January 2022

Psoriatic arthritis among Egyptian patients with psoriasis attending the dermatology clinic: prevalence, comorbidities, and clinical predictors.

Reumatologia 2021 5;59(6):394-401. Epub 2022 Jan 5.

Rheumatology Department, Cairo University, Egypt.

Objectives: Early diagnosis and treatment of psoriatic arthritis (PsA) help to prevent progressive joint involvement and disabilities. There is a problem in the early diagnosis of PsA worldwide, which may be attributed to the dermatologists missing PsA symptoms and signs and a lack of effective screening tools.

Aim Of The Study: The current study was designed to assess the prevalence, comorbidities, and clinical predictors associated with the development of PsA in psoriasis patients. Read More

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January 2022

Carbohydrate antigen 125 and risk of heart failure readmissions in patients with heart failure and preserved ejection fraction.

Sci Rep 2022 Jan 25;12(1):1344. Epub 2022 Jan 25.

Cardiology Department, Hospital Clínico Universitario de Valencia, Universitat de Valencia, INCLIVA, Avda. Blasco Ibáñez 17, 46010, Valencia, Spain.

We aimed to assess the association between CA125 and the long-term risk of total acute heart failure (AHF) admissions in patients with an index hospitalization with AHF and preserved ejection fraction (HFpEF). We prospectively included 2369 patients between 2008 and 2019 in three centers. CA125 and NT-proBNP were measured during early hospitalization and evaluated as continuous and categorized in quartiles (Q). Read More

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January 2022

The impact of FFP3 respirators on the blood saturation.

Sci Rep 2022 Jan 25;12(1):1335. Epub 2022 Jan 25.

Department of Neurology, University of Zielona Gora, 65-046, Zielona Gora, Poland.

This study aims to investigate whether wearing a filtering facepiece class 3 respirators with personal protective equipment (FPP3/PPE) during work in the intensive care unit (ICU) affects the blood saturation (SpO2), the heart rate (HR), and the well-being of health care workers (HCWs). This preliminary study included a group of 21 volunteers (including 16 females (76%), with a median age of 23 years). Each worker served as his own control and performed the test two times: they wore the FFP3/PPE and did not wear it for a three-hour shift in the ICU. Read More

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January 2022

Acute ischaemic stroke associated with SARS-CoV-2 infection in North America.

J Neurol Neurosurg Psychiatry 2022 Jan 25. Epub 2022 Jan 25.

Calgary Stroke Program, Cumming School of Medicine, Calgary, AB, Canada.

Background: To analyse the clinical characteristics of COVID-19 with acute ischaemic stroke (AIS) and identify factors predicting functional outcome.

Methods: Multicentre retrospective cohort study of COVID-19 patients with AIS who presented to 30 stroke centres in the USA and Canada between 14 March and 30 August 2020. The primary endpoint was poor functional outcome, defined as a modified Rankin Scale (mRS) of 5 or 6 at discharge. Read More

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January 2022

Durability of Endoscopes Used During Routine Lumbar Endoscopy: An Analysis of Use Patterns, Common Failure Modes, Impact on Patient Care, and Contingency Plans.

Int J Spine Surg 2021 Dec;15(6):1135-1148

University of New Mexico School of Medicine, Albuquerque, New MexicoDesert Institute for Spine Care, Phoenix, USA.

Background: Successful implementation of endoscopic spinal surgery programs hinges on reliable performance and case cost similar to traditional decompression surgeries of the lumbar spine.

Materials And Methods: To improve the statistical power of studying the durability of endoscopes with routine lumbar endoscopy, the authors performed a retrospective survey study among endoscopic spine surgeons by email and chat groups on social media networks WhatsApp and WeChat. Descriptive and correlative statistics were done on the surgeon's responses recorded in multiple-choice questions. Read More

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December 2021

Prevalence of Obesity in Patients with Dysphonia.

J Voice 2022 Jan 22. Epub 2022 Jan 22.

Department of Otolaryngology and Head & Neck Surgery, American University of Beirut-Medical Center, Lebanon. Electronic address:

Objective: To investigate the prevalence of obesity in patients with dysphonia and the association between Body Mass Index (BMI) and the Voice Handicap Index-10 (VHI-10).

Material And Methods: This is a retrospective study that included 304 patients who visited the senior author's Otolaryngology practice between the years 2018 and 2020. Patients were divided into two groups, those presenting for dysphonia and those presenting for other otolaryngologic complaints (Controls). Read More

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January 2022

Fresh fruit consumption, physical activity, and five-year risk of mortality among patients with type 2 diabetes: A prospective follow-up study.

Nutr Metab Cardiovasc Dis 2021 Nov 8. Epub 2021 Nov 8.

Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, 210009, China. Electronic address:

Background And Aims: We explored the associations among fruit consumption, physical activity, and their dose-response relationship with all-cause and cardiovascular disease (CVD) mortality in type 2 diabetic patients.

Methods And Results: We prospectively followed 20,340 community-dwelling type 2 diabetic patients aged 21-94 years. Information on diets and physical activity was collected using standardized questionnaires. Read More

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November 2021

Prognostic nomogram for risk of mortality after hip fracture surgery in geriatrics.

Injury 2022 Jan 19. Epub 2022 Jan 19.

Department of Orthopedics, Peking University First Hospital, No 8 Xishiku Street, XiCheng, Beijing 100034, PR China. Electronic address:

Purpose: Hip fracture is a significant public health problem, with associated high morbidity and mortality. Orthopedic surgeons are concerned to improve prognosis and stratify mortality risk after hip fracture surgery. This study established a nomogram that combines the Charlson Comorbidity Index (CCI) with specific laboratory parameters to predict mortality risk after hip fracture surgery in geriatrics. Read More

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January 2022

Magnitude and determinants of unmet need for family planning among reproductive age women in East Africa: multilevel analysis of recent demographic and health survey data.

Contracept Reprod Med 2022 Jan 25;7(1). Epub 2022 Jan 25.

Department of Epidemiology and Biostatistics, School Public Health, College of Medicine and Health Science Mizan-Tepi University, P.O. Box 26o, Mizan-Aman, Ethiopia.

Introduction: Unmet need for family planning is the main obstacle to achieve healthy timing and desired number of children. Decreasing the unmet need for FP respects and protects human right and help to decrease the influence on biodiversity. Unmet need for family planning is the contributor and devastating issue of maternal health. Read More

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January 2022

Transcutaneous auricular vagus nerve stimulation (taVNS) for the treatment of pediatric nephrotic syndrome: a pilot study.

Bioelectron Med 2022 Jan 26;8(1). Epub 2022 Jan 26.

Cohen Children's Medical Center of New York, New Hyde Park, United States, NY.

Background: Children with frequently relapsing nephrotic syndrome (FRNS) and steroid resistant nephrotic syndrome (SRNS) are exposed to immunosuppressant medications with adverse side effects and variable efficacy. Transcutaneous auricular vagus nerve stimulation (taVNS) modulates the immune system via the inflammatory reflex and has become a therapy of interest for treating immune-mediated illnesses.

Methods: An open-label, pilot study of tavNS for five minutes daily for 26 weeks via a TENS 7000 unit was conducted. Read More

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January 2022

Adherence to malaria management guidelines by health care workers in the Busoga sub-region, eastern Uganda.

Malar J 2022 Jan 25;21(1):25. Epub 2022 Jan 25.

Clinical Epidemiology Unit, Makerere University, College of Health Sciences, Kampala, Uganda.

Background: Appropriate malaria management is a key malaria control strategy. The objective of this study was to determine health care worker adherence levels to malaria case management guidelines in the Busoga sub-region, Uganda.

Methods: Health facility assessments, health care worker (HCW), and patient exit interview (PEI) surveys were conducted at government and private health facilities in the sub-region. Read More

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January 2022

A cognitively enhanced online Tai Ji Quan training intervention for community-dwelling older adults with mild cognitive impairment: A feasibility trial.

BMC Geriatr 2022 Jan 25;22(1):76. Epub 2022 Jan 25.

Knight Cancer Institute, Oregon Health & Science University, Portland, OR, 97239, USA.

Background: This study examines the feasibility, acceptability, and safety of a newly developed cognitive-enhancing Tai Ji Quan training intervention, delivered via remote videoconferencing, for older adults with mild cognitive impairment (MCI).

Methods: In a three-arm feasibility trial, community-dwelling older adults with MCI (N = 69; mean age = 74.6 years, 57% women) were randomized to a cognitively enhanced Tai Ji Quan (n = 23), standard Tai Ji Quan (n = 22), or stretching group (n = 24) and participated in a 60-minute online exercise session via Zoom, twice weekly for 16 weeks. Read More

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January 2022

Arthroscopic release of the pectoralis minor tendon as an adjunct to acromioplasty in the treatment of subacromial syndrome associated with scapular dyskinesia.

Orthop Traumatol Surg Res 2022 Jan 22:103211. Epub 2022 Jan 22.

Centre de la main, 47, rue de la Foucaudière, 49000 Trélazé, France.

Introduction: One of the causes of scapular dyskinesia is the retraction of the pectoralis minor muscle. It can be the cause of shoulder pain associated with increased anterior tilt and internal rotation of the shoulder.

Hypothesis: Arthroscopic release of the pectoralis minor tendon is effective for shoulder pain, linked to a correction of dyskinesia, resulting in the early disappearance of scapulalgia. Read More

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January 2022

The epidemiology of out-of-hospital cardiac arrest in Australia and New Zealand: A binational report from the Australasian Resuscitation Outcomes Consortium (Aus-ROC).

Resuscitation 2022 Jan 22. Epub 2022 Jan 22.

Department of Epidemiology and Preventive Medicine, Monash University, Victoria, Australia; Prehospital, Resuscitation and Emergency Care Research Unit (PRECRU), Curtin University, Western Australia, Australia; St John Western Australia, Western Australia, Australia.

Introduction: The Australasian Resuscitation Outcomes Consortium (Aus-ROC) out-of-hospital cardiac arrest (OHCA) Epistry (Epidemiological Registry) now covers 100% of Australia and New Zealand (NZ). This study reports and compares the Utstein demographics, arrest characteristics and outcomes of OHCA patients across our region.

Methods: We included all OHCA cases throughout 2019 as submitted to the Epistry by the eight Australian and two NZ emergency medical services (EMS). Read More

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January 2022