26 results match your criteria 5153 children

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Contrast-enhanced voiding urosonography in the diagnosis of intrarenal reflux.

J Ultrasound 2021 Feb 26. Epub 2021 Feb 26.

Children's Hospital Zagreb, Ul. Vjekoslava Klaića 16, 10000, Zagreb, Croatia.

Purpose: Although contrast-enhanced urosonography (ceVUS) has shown capable diagnostic accuracy for the diagnosis of vesicoureteral reflux (VUR) in children, the ability of ceVUS to detect intrarenal reflux (IRR) is considered limited. The purpose of our study is to assess the ability of ceVUS to detect IRR as well as its association with age, gender, and the grade of VUR.

Methods: This study included 5153 children who were referred to our clinic for ceVUS. Read More

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February 2021

Proactive Lactation Care is Associated With Improved Outcomes in a Referral NICU.

J Hum Lact 2021 Feb 13:890334421993467. Epub 2021 Feb 13.

10051 Princess Margaret Hospital, Toronto, Canada.

Background: Mother's milk improves outcomes. Referral neonatal intensive care units face unique lactation challenges with maternal-infant separation and maternal pump dependency. Little is known about lactation resource allocation in this high-risk population. Read More

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February 2021

Exploring the Impact of Remoteness and Socio-Economic Status on Child and Adolescent Injury-Related Mortality in Australia.

Children (Basel) 2020 Dec 24;8(1). Epub 2020 Dec 24.

College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, QLD 4811, Australia.

Injuries are a leading cause of harm for children. This study explores the impact of determinants of health on children (0-19 years) injury-related mortality (namely remoteness and socio-economic disadvantage, calculated using the index of relative socio-economic advantage and disadvantage (IRSAD)). Cause of death data from the Australian Bureau of Statistics were sourced for children in Australia between 1 July 2007 to 30 June 2017. Read More

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December 2020

Case Report: Endoscopic Removal of an Eroded Gastric Band Causing Small Bowel Obstruction upon Migration into the Proximal Jejunum.

Obes Surg 2020 Dec 11;30(12):5153-5156. Epub 2020 Aug 11.

Department of Minimally Invasive and Bariatric Surgery, Hôpital du Sacré-Coeur, CIUSSS du Nord de l'île de Montréal, 5400 Boulevard Gouin Ouest H4J 1C5, Québec, Montréal, Canada.

Background: Adjustable gastric banding (AGB) is on the decline due to its relatively modest amount of expected weight loss, coupled with high rates of revision and complications such as band erosion. Management of eroded gastric bands can be challenging especially when complete intra-gastric erosion is followed by distal migration causing small bowel obstruction.

Methods: We present an endoscopic option of using a pediatric colonoscope to remove an eroded AGB causing jejunal obstruction. Read More

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December 2020

The Proximity of Spatial Clusters of Low Birth Weight and Risk Factors: Defining a Neighborhood for Focused Interventions.

Matern Child Health J 2020 Aug;24(8):1065-1072

Department of Mathematics and Statistics, University of West Florida, Building 4, Room 336, 1111 University Parkway, Pensacola, USA.

Background: Low birth weight (LBW) is associated with significant mortality and morbidity and remains a significant preventable problem. Risk factors include socioeconomic, demographics, and characteristics of the environment. Spatial analysis can uncover unusual frequencies of health problems in neighborhoods, eventually leading to insights for targeted interventions. Read More

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The changing epidemiology of herpes zoster over a decade in South Korea, 2006-2015.

Vaccine 2019 08 31;37(36):5153-5160. Epub 2019 Jul 31.

Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

Background: In South Korea, the population is rapidly aging and the prevalence of comorbidities has increased. We investigated longitudinal changes in the herpes zoster (HZ) considering demographic changes and comorbidities in the era of universal single-dose varicella vaccination.

Methods: We used the population-based database of the National Health Insurance Service in South Korea, with approximately 50 million subscribers during 2006-2015. Read More

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Risk Factors and Outcomes From All-Terrain Vehicle Injuries Compared With Motor Vehicle Collisions in Children.

Clin Pediatr (Phila) 2019 10 12;58(11-12):1255-1261. Epub 2019 Jun 12.

University of Pittsburgh, Pittsburgh, PA, USA.

We compared risk factors and outcomes of children injured from all-terrain vehicle (ATV) injuries to those injured from motor vehicle collisions (MVC). We reviewed records of patients ≤18 years of age admitted to a trauma center with ATV- or MVC-related injuries between January 1, 2000, and December 31, 2015. Demographics were compared using logistic regression. Read More

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October 2019

Fronto-limbic white matter microstructure, behavior, and emotion regulation in survivors of pediatric brain tumor.

J Neurooncol 2019 Jul 9;143(3):483-493. Epub 2019 May 9.

Center for Biobehavioral Health, The Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, USA.

Purpose: After treatment, pediatric brain tumor survivors (PBTS) face emotional and behavioral challenges, perhaps due to tumor or treatment-related changes in brain structures involved in emotion regulation, including those with fronto-limbic connections. We hypothesized that relative to healthy controls (HCs), PBTS would exhibit greater difficulties with behavior and emotional functioning, and display reduced mean fractional anisotropy (mFA) in white matter tracts with fronto-limbic connections including the cingulum bundle (CB), inferior fronto-occipital fasciculus (IFOF), and uncinate fasciculus (UF). We further predicted that mFA would account for variance in the relationship between group and emotional/behavioral outcome. Read More

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Psyche Meets the Gatekeepers: Creating a More Humane Culture for Women in Medicine.

Acad Med 2019 11;94(11):1665-1669

S.M. Flaherty is communications director, Center for Celiac Research and Treatment, MassGeneral Hospital for Children, Boston, Massachusetts; ORCID: http://orcid.org/0000-0002-5153-0218. M. Misra is professor of pediatrics, Harvard Medical School, and chief, Division of Pediatric Endocrinology, MassGeneral Hospital for Children, Boston, Massachusetts. S.E. Scott-Vernaglia is assistant professor of pediatrics, Harvard Medical School, and director, Pediatric Residency Program, MassGeneral Hospital for Children, Boston, Massachusetts. E.M. Taveras is professor of pediatrics, Harvard Medical School, and chief, Division of General Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts. E.J. Israel is assistant professor of pediatrics, Harvard Medical School, and associate unit chief, Division of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Boston, Massachusetts.

In the Greek myth of Psyche and Eros, Psyche must fulfill four seemingly impossible tasks to achieve full consciousness before she can be reunited with her bridegroom, Eros. From early childhood, girls and women can encounter gender stereotyping, sexual harassment and assault, and other gender-related challenges. Although both men and women can face mistreatment in medical school, female students experience sexual harassment and sexual assault at higher rates than male students. Read More

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November 2019

Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion-dependent beta thalassaemia.

Cochrane Database Syst Rev 2018 07 12;7:CD011626. Epub 2018 Jul 12.

University of Florida, Sacred Heart Children's Hospital, 6th Floor Nemours, 5153 North 9th Avenue, Pensacola, Florida, USA, 32504.

Background: Beta thalassaemia is a common inherited blood disorder. The need for frequent blood transfusions in this condition poses a difficult problem to healthcare systems. The most common cause of morbidity and mortality is cardiac dysfunction from iron overload. Read More

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Commonest Cancers in Pakistan - Findings and Histopathological Perspective from a Premier Surgical Pathology Center in Pakistan.

Asian Pac J Cancer Prev 2016 ;17(3):1061-75

Pathology and Laboratory Medicine, Histopathology, Aga Khan University Hospital, Karachi, Pakistan E-mail :

Context: There are no recent authoritative data about incidence and prevalence of various types of cancers in Pakistan.

Aim: To determine the frequency of malignant tumors seen in our practice and provide a foundation for building a comprehensive cancer care strategy.

Materials And Methods: 10,000 successive cases of solid malignant tumors reported in 2014 were included. Read More

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January 2017

Cyclic Vomiting Syndrome in Infants and Children: A Clinical Follow-Up Study.

Pediatr Neurol 2016 Apr 7;57:29-33. Epub 2016 Jan 7.

Department of Pediatrics, Teikyo University School of Medicine, Itabashi-Ku, Tokyo, Japan.

Background: Cyclic vomiting syndrome is characterized by recurrent vomiting that is associated with increased adrenocorticotropic hormone and antidiuretic hormone levels during cyclic vomiting syndrome attacks. However, both prognosis and treatment remain unclear. We therefore evaluated the clinical features, prognosis, and effectiveness of the prophylaxis of cyclic vomiting syndrome as well as the relationship between symptoms and adrenocorticotropic hormone/antidiuretic hormone levels. Read More

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Factors Associated With Mortality in Pediatric vs Adult Nasopharyngeal Carcinoma.

JAMA Otolaryngol Head Neck Surg 2016 Mar;142(3):217-22

Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle.

Importance: Nasopharyngeal carcinoma (NPC) is endemic in some Asian regions but is uncommon in the United States. Little is known about the racial, demographic, and biological characteristics of the disease in pediatric patients.

Objectives: To improve understanding of the differences between pediatric and adult NPC and to determine whether race conferred a survival difference among pediatric patients with NPC. Read More

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Effectiveness of hormonal contraception in HIV-infected women using antiretroviral therapy.

AIDS 2015 Nov;29(17):2353-9

aDepartment of Epidemiology bDepartment of Global Health cDepartment of Medicine, University of Washington, Seattle, Washington, USA dDepartment of Obstetrics & Gynaecology, University of Nairobi eSexual, Reproductive, Adolescent and Child Health Research Program, Kenya Medical Research Institute, Nairobi, Kenya fFHI 360, Contraceptive Technology Innovation Department, Durham, North Carolina gDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA hDepartment of Reproductive Health, Moi University, Eldoret, Kenya iWits Reproductive Health and HIV Institute (WRHI), University of the Witwatersrand, Johannesburg, South Africa jCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.

Objective: The objective of this study is to assess whether antiretroviral therapy (ART) may diminish the effectiveness of hormonal contraceptive methods.

Methods: Using data from 5153 HIV-infected women followed prospectively for 1-3 years in three HIV prevention studies in Africa, we compared incident pregnancy rates by contraceptive method (implant, injectable, oral or none) and ART use. Multivariable Cox regression models were used to determine adjusted hazard ratios (aHRs) and test interactions between each method and ART use. Read More

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November 2015

The impact of obesity on pediatric procedural sedation-related outcomes: results from the Pediatric Sedation Research Consortium.

Paediatr Anaesth 2015 Jul 27;25(7):689-97. Epub 2015 Mar 27.

Division of Pediatric Critical Care, Department of Pediatrics, University of Louisville, Louisville, KY, USA.

Objectives: To evaluate the impact of obesity on adverse events and required interventions during pediatric procedural sedation.

Methods: The Pediatric Sedation Research Consortium database of prospectively collected procedural sedation encounters was queried to identify patients for whom body mass index (BMI) could be calculated. Obesity was defined as BMI ≥95th percentile for age and gender. Read More

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Maternal early-pregnancy thyroid function is associated with subsequent hypertensive disorders of pregnancy: the generation R study.

J Clin Endocrinol Metab 2014 Dec;99(12):E2591-8

The Generation R Study Group (M.M., T.I.M.K., S.S.-T., R.G., V.W.V.J.) and Departments of Internal Medicine (M.M., T.I.M.K., Y.B.d.R., W.E.V., T.J.V., R.P.P.), Epidemiology (R.G., A.H., V.W.V.J.), and Immunology (H.H.), Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands; and Departments of Obstetrics and Gynecology (S.S.-T., W.V., E.A.P.S.), Pediatrics (R.G., S.M.P.F.d.M.K.-S., J.J.B.-S., H.T., V.W.V.J.), Clinical Chemistry (Y.B.d.R.), and Child and Adolescent Psychiatry (H.T.), Erasmus Medical Center, Sophia Children's Hospital, 3000 DR Rotterdam, The Netherlands.

Context: Hypertensive disorders during pregnancy are associated with a wide range of maternal and fetal complications, and only a few risk factors are known for the development of these disorders during pregnancy. Conflicting and limited data are available on the relationship between thyroid (dys)function and the risk of hypertensive disorders of pregnancy.

Objective: The objective of the investigation was to study the associations between early-pregnancy thyroid dysfunction, thyroid function within the normal range, and the risk of hypertensive disorders. Read More

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December 2014

Exposure to bath salts and synthetic tetrahydrocannabinol from 2009 to 2012 in the United States.

Kelly E Wood

J Pediatr 2013 Jul 4;163(1):213-6. Epub 2013 Feb 4.

Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

Objective: To describe bath salts and synthetic tetrahydrocannabinol (THC) exposures in the US from 2009 to 2012, hypothesizing a yearly increase.

Study Design: All exposures reported to American Association of Poison Control Centers between January 1, 2009, and April 30, 2012, were extracted from the National Poison Data System using generic and product codes.

Results: Bath salts and synthetic THC exposures totaled 7467 and 11,561, respectively. Read More

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Antimicrobial resistance in urinary bacterial isolates from pregnant women in rural Tanzania: implications for public health.

Scand J Infect Dis 2005 ;37(4):262-8

Centre for International Health and, University of Bergen, Norway.

Treatment of asymptomatic bacteriuria and urinary tract infections in pregnancy can prevent adverse outcome for mother and child. However, antimicrobial resistance can impede effective chemotherapy. From April 1995 to March 1996, urine specimens from 5153 pregnant women in a rural area in northern Tanzania were inoculated on dip slides. Read More

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Microarrays for genotyping human group a rotavirus by multiplex capture and type-specific primer extension.

J Clin Microbiol 2003 Nov;41(11):5153-8

Molecular Medicine, Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden.

Human group A rotavirus (HRV) is the major cause of severe gastroenteritis in infants worldwide. HRV shares the feature of a high degree of genetic diversity with many other RNA viruses, and therefore, genotyping of this organism is more complicated than genotyping of more stable DNA viruses. We describe a novel microarray-based method that allows high-throughput genotyping of RNA viruses with a high degree of polymorphism by multiplex capture and type-specific extension on microarrays. Read More

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November 2003

Transphyseal fracture-dislocation of the femoral neck: a case report and review of the literature.

J Orthop Trauma 2003 Oct;17(9):648-53

Department of Orthopaedics, Nemours Children's Clinic-Pensacola, 5153 North 9th Avenue, Pensacola, FL 32504, USA.

We describe a case of transphyseal hip fracture-dislocation in a 7.5-year-old patient who was treated initially by open reduction and internal fixation. Soon after the injury, the femoral head developed avascular necrosis. Read More

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October 2003

Earlier use of adjunctive vagus nerve stimulation therapy for refractory epilepsy.

Neurology 2002 Sep;59(6 Suppl 4):S26-30

Child Neurology Center of Northwest Florida, 5153 North 9th Avenue, Suite 300, Pensacola, FL 32504, USA.

Recent studies suggest that epilepsy that is unresponsive to medical therapy is likely to be refractory from the onset. Identifying such patients early and treating them with nonpharmacologic therapies may improve their outcome. We hypothesized that patients who had adjunctive therapy with vagus nerve stimulation (VNS) earlier in the course of their epilepsy would have a better response compared with patients who had VNS therapy instituted later in the course. Read More

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September 2002

Rubella antibody persistence after immunization.

JAMA 1982 Jan;247(2):193-6

A comparative field trial of three live, attenuated rubella virus vaccines (Cendehill, HPV 77 DE-5, and HPV-77 DK-12) was initiated in 1969 on the islands of Kauai and Hawaii in the state of Hawaii. Following initial seroconversion rates of more than 98%, periodic serological testing of the study population was conducted to assess the durability of vaccine-induced immunity. In February 1980, ten years after the initiation of the study, 741 of the 5,153 original susceptible vaccinees were still enrolled in the study. Read More

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January 1982

Rubella immunization. Persistence of antibody four years after a large-scale field trial.

JAMA 1976 May;235(20):2201-4

A long-term comparative field trial of three live, attenuated rubella vaccines (HPV-77 DE-5, HPV-77 DK-12, and Cendehill) was initiated in 1969 on the islands of Kauai and Hawaii in the state of Hawaii. Rubella hemagglutination-inhibition (HI) tests on prevaccination serum specimens from 7,931 children in the two study areas indicated an overall susceptibility to rubella of nearly 70%. The rates of seroconversion of 5,153 seronegative subjects to HPV-77 DE-5, HPV-77 DK-12, and Cendehill vaccine were 97. Read More

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