Anal Chim Acta 2018 Aug 22;1019:74-83. Epub 2018 Mar 22.
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore; National University of Singapore, Environmental Research Institute, T-Lab Building #02-01, 5A Engineering Drive 1, Singapore 117411, Singapore; Tropical Marine Science Institute, National University of Singapore, S2S, 18 Kent Ridge Road, Singapore 119227, Singapore. Electronic address:
An automated bundled hollow fiber array (BHF)-liquid-phase microextraction (LPME) methodology in combination with ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) has been developed for the determination of perfluorinated compounds (PFCs) in environmental aqueous matrices. Eight PFCs were considered, including perfluoroheptanoic acid, perfluorooctanoic acid, perfluorononanoic acid, perfluorodecanoic acid, perfluoroundecanoic acid, perfluorododecanoic acid, perfluorotridecanoic acid, perfluorotetradecanoic acid. Experimental parameters influencing extraction efficiency, such as number of hollow fibers in the BHF extraction device, type of extraction and desorption solvent, extraction conditions (stirring rate, temperature and duration), elution conditions and the salting out effect were examined. Read More