19 results match your criteria 3d Printing And Additive Manufacturing[Journal]

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Development and Testing of an Ultrasound-Compatible Cardiac Phantom for Interventional Procedure Simulation Using Direct Three-Dimensional Printing.

3D Print Addit Manuf 2020 Dec 16;7(6):269-278. Epub 2020 Dec 16.

School of Biomedical Engineering & Imaging Sciences, St Thomas' Hospital, King's College London, London, United Kingdom.

Organ phantoms are widely used for evaluating medical technologies, training clinical practitioners, as well as surgical planning. In the context of cardiovascular disease, a patient-specific cardiac phantom can play an important role for interventional cardiology procedures. However, phantoms with complicated structures are difficult to fabricate by conventional manufacturing methods. Read More

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December 2020

Oxygen-Permeable Films for Continuous Additive, Subtractive, and Hybrid Additive/Subtractive Manufacturing.

3D Print Addit Manuf 2020 Oct 15;7(5):216-221. Epub 2020 Oct 15.

Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, New York, USA.

In the past 5 years, oxygen-permeable films have been widely used for continuous additive manufacturing. These films create a polymerization inhibition zone that facilitates continuous printing in the additive mode of fabrication. Typically, oxygen-permeable films made out of Teflon are currently used. Read More

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October 2020

Novel Poly(-caprolactone)/Graphene Scaffolds for Bone Cancer Treatment and Bone Regeneration.

3D Print Addit Manuf 2020 Oct 15;7(5):222-229. Epub 2020 Oct 15.

Department of Mechanical, Aerospace and Civil Engineering, School of Engineering, Faculty of Science and Engineering, The University of Manchester, Manchester, United Kingdom.

Scaffold-based bone tissue engineering is the most relevant approach for critical-sized bone defects. It is based on the use of three-dimensional substrates to provide the appropriate biomechanical environment for bone regeneration. Despite some successful results previously reported, scaffolds were never designed for disease treatment applications. Read More

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October 2020

Three-Dimensional Printed Stamps for the Fabrication of Patterned Microwells and High-Throughput Production of Homogeneous Cell Spheroids.

3D Print Addit Manuf 2020 Jun 5;7(3):139-147. Epub 2020 Jun 5.

Department of Biomedical Engineering, University of California, Davis, Davis, California, USA.

Aggregation of cells into spheroids and organoids is a promising tool for regenerative medicine, cancer and cell biology, and drug discovery due to their recapitulation of the cell-cell and cell-matrix interactions found . Traditional approaches for the production of spheroids, such as the hanging drop method, are limited by the lack of reproducibility and the use of labor-intensive and time-consuming techniques. The need for high-throughput approaches allowing for the quick and reproducible formation of cell aggregates has driven the development of soft lithography techniques based on the patterning of microwells into nonadherent hydrogels. Read More

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Three-Dimensional Printing and Electrospinning Dual-Scale Polycaprolactone Scaffolds with Low-Density and Oriented Fibers to Promote Cell Alignment.

3D Print Addit Manuf 2020 Jun 5;7(3):105-113. Epub 2020 Jun 5.

Department of Mechanical, Aerospace, and Civil Engineering and University of Manchester, Manchester, United Kingdom.

Complex and hierarchically functionalized scaffolds composed of micro- and nanoscale structures are a key goal in tissue engineering. The combination of three-dimensional (3D) printing and electrospinning enables the fabrication of these multiscale structures. This study presents a polycaprolactone 3D-printed and electrospun scaffold with multiple mesh layers and fiber densities. Read More

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Agarose Slurry as a Support Medium for Bioprinting and Culturing Freestanding Cell-Laden Hydrogel Constructs

3D Print Addit Manuf 2019 Jun 28;6(3):158-164. Epub 2019 Mar 28.

Department of Pharmacology and Physiology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.

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Three-Dimensional Printing Antimicrobial and Radiopaque Constructs.

3D Print Addit Manuf 2018 Mar 1;5(1):29-35. Epub 2018 Mar 1.

Department of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, Louisiana.

Three-dimensional (3D) printing holds tremendous potential as a tool for patient-specific devices. This proof-of- concept study demonstrated the feasibility, antimicrobial properties, and computed tomography(CT) imaging characteristics of iodine/polyvinyl alcohol (PVA) 3D meshes and stents. Under scanning electron microscopy, cross-linked PVA displays smoother and more compacted filament arrangements. Read More

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Osseointegration of Coarse and Fine Textured Implants Manufactured by Electron Beam Melting and Direct Metal Laser Sintering.

3D Print Addit Manuf 2017 Jun;4(2):91-97

Department of Biomedical Engineering, University of North Carolina-NC State University, Chapel Hill-Raleigh, North Carolina.

Osseointegrated implants transfer loads from native bone to a synthetic joint and can also function transdermally to provide a stable connection between the skeleton and the prostheses, eliminating many problems associated with socket prostheses. Additive manufacturing provides a cost-effective means to create patient-specific implants and allows for customized textures for integration with bone and other tissues. Our objective was to compare the osseointegration strength of two primary additive manufacturing methods of producing textured implants: electron beam melting (EBM) (mean Ra = 23 μm) and direct metal laser sintering (DMLS) (mean Ra = 10 μm). Read More

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3D Systems' Technology Overview and New Applications in Manufacturing, Engineering, Science, and Education.

3D Print Addit Manuf 2014 Sep;1(3):169-176

NASA Johnson Space Center, Houston, Texas.

Since the inception of 3D printing, an evolutionary process has taken place in which specific user and customer needs have crossed paths with the capabilities of a growing number of machines to create value-added businesses. Even today, over 30 years later, the growth of 3D printing and its utilization for the good of society is often limited by the various users' understanding of the technology for their specific needs. This article presents an overview of current 3D printing technologies and shows numerous examples from a multitude of fields from manufacturing to education. Read More

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September 2014

Computationally Designed 3D Printed Self-Expandable Polymer Stents with Biodegradation Capacity for Minimally Invasive Heart Valve Implantation: A Proof-of-Concept Study.

3D Print Addit Manuf 2017 Mar;4(1):19-29

Department of Biomedical Engineering, Group of Soft Tissue Biomechanics and Tissue Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

The evolution of minimally invasive implantation procedures and the remodeling potential of decellularized tissue-engineered heart valves require stents with growth capacity to make these techniques available for pediatric patients. By means of computational tools and 3D printing technology, this proof-of-concept study demonstrates the design and manufacture of a polymer stent with a mechanical performance comparable to that of conventional nitinol stents used for heart valve implantation in animal trials. A commercially available 3D printing polymer was selected, and crush and crimping tests were conducted to validate the results predicted by the computational model. Read More

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Rapid Prototyping of Inspired Gas Delivery System for Pulmonary MRI Research.

3D Print Addit Manuf 2015 Dec;2(4):196-203

Department of Medicine, University of California, San Diego, La Jolla, California.; Department of Radiology, University of California, San Diego, La Jolla, California.

Specific ventilation imaging (SVI) is a noninvasive magnetic resonance imaging (MRI)-based method for determining the regional distribution of inspired air in the lungs, useful for the assessment of pulmonary function in medical research. This technique works by monitoring the rate of magnetic resonance signal change in response to a series of imposed step changes in inspired oxygen concentration. The current SVI technique requires a complex system of tubes, valves, and electronics that are used to supply and rapidly switch inspired gases while subjects are imaged, which makes the technique difficult to translate into the clinical setting. Read More

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December 2015

Curved Layer Fused Filament Fabrication Using Automated Toolpath Generation.

3D Print Addit Manuf 2016 Dec;3(4):236-243

Department of Mechanical Engineering, University of Bath, Bath, United Kingdom.

An automated method for the generation of curved layer toolpaths is demonstrated to produce 3D printed components with improved aesthetic and structural properties using fused filament fabrication printing. Three case studies are shown, which demonstrate the ability of the G-code generating algorithm to resolve concave and convex structures. The combination of conventionally printed layers and curved layers within a single print is also demonstrated by producing double skin curved layer sandwich structures with static printed cores. Read More

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December 2016

Conformal Robotic Stereolithography.

3D Print Addit Manuf 2016 Dec;3(4):226-235

Department of Mechanical Engineering and Laboratory for Manufacturing and Productivity, Massachusetts Institute of Technology, Cambridge, Massachusetts.

Additive manufacturing by layerwise photopolymerization, commonly called stereolithography (SLA), is attractive due to its high resolution and diversity of materials chemistry. However, traditional SLA methods are restricted to planar substrates and planar layers that are perpendicular to a single-axis build direction. Here, we present a robotic system that is capable of maskless layerwise photopolymerization on curved surfaces, enabling production of large-area conformal patterns and the construction of conformal freeform objects. Read More

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December 2016

Spatial Control of Bacteria Using Screen Printing.

3D Print Addit Manuf 2016 Dec;3(4):194-203

Department of Biomedical Engineering, Columbia University, New York, New York.

Synthetic biology has led to advances in both our understanding and engineering of genetic circuits that affect spatial and temporal behaviors in living cells. A growing array of native and synthetic circuits such as oscillators, pattern generators, and cell-cell communication systems has been studied, which exhibit spatiotemporal properties. To better understand the design principles of these genetic circuits, there is a need for versatile and precise methods for patterning cell populations in various configurations. Read More

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December 2016

Enhanced Osteoblast Response to Porosity and Resolution of Additively Manufactured Ti-6Al-4V Constructs with Trabeculae-Inspired Porosity.

3D Print Addit Manuf 2016 Mar;3(1):10-21

Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, Virginia.

The addition of porosity to the traditionally used solid titanium metal implants has been suggested to more closely mimic the natural mechanical properties of bone and increase osseointegration in dental and orthopedic implants. The objective of this study was to evaluate cellular response to three-dimensional (3D) porous Ti-6Al-4V constructs fabricated by additive manufacturing using laser sintering with low porosity (LP), medium porosity (MP), and high porosity (HP) with low resolution (LR) and high resolution (HR) based on a computed tomography scan of human trabecular bone. After surface processing, construct porosity ranged from 41. Read More

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3D Printing of Personalized Artificial Bone Scaffolds.

3D Print Addit Manuf 2015 Jun;2(2):56-64

Division of Musculoskeletal Sciences, Department of Orthopaedics and Rehabilitation, Penn State College of Medicine, Hershey, Pennsylvania.

Additive manufacturing technologies, including three-dimensional printing (3DP), have unlocked new possibilities for bone tissue engineering. Long-term regeneration of normal anatomic structure, shape, and function is clinically important subsequent to bone trauma, tumor, infection, nonunion after fracture, or congenital abnormality. Due to the great complexity in structure and properties of bone across the population, along with variation in the type of injury or defect, currently available treatments for larger bone defects that support load often fail in replicating the anatomic shape and structure of the lost bone tissue. Read More

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The NIH 3D Print Exchange: A Public Resource for Bioscientific and Biomedical 3D Prints.

3D Print Addit Manuf 2014 Sep;1(3):137-140

Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland.

The National Institutes of Health (NIH) has launched the NIH 3D Print Exchange, an online portal for discovering and creating bioscientifically relevant 3D models suitable for 3D printing, to provide both researchers and educators with a trusted source to discover accurate and informative models. There are a number of online resources for 3D prints, but there is a paucity of scientific models, and the expertise required to generate and validate such models remains a barrier. The NIH 3D Print Exchange fills this gap by providing novel, web-based tools that empower users with the ability to create ready-to-print 3D files from molecular structure data, microscopy image stacks, and computed tomography scan data. Read More

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September 2014

3D-Printed Tissue-Mimicking Phantoms for Medical Imaging and Computational Validation Applications.

3D Print Addit Manuf 2014 Mar;1(1):14-23

Centre for Applied Biomedical Engineering Research, Department of Mechanical, Aeronautical and Biomedical Engineering, University of Limerick, Limerick, Ireland.

in vivo Read More

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