Pediatr Infect Dis J 2021 Nov 30. Epub 2021 Nov 30.
From the SolidarMed, Partnerships for Health, Maseru, Lesotho Institute of Global Health, University of Geneva, Geneva, Switzerland Department of Medicine, Swiss Tropical & Public Health Institute, Basel, Switzerland Molecular Virology, Department of Biomedicine, University of Basel, Basel, Switzerland University of Basel, Basel, Switzerland Ministry of Health of Lesotho, Maseru, Lesotho Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland.
Background: Children living with HIV and taking antiretroviral therapy (ART) are a priority group for routine viral load (VL) monitoring. As per Lesotho guidelines, a VL ≥1000 copies/mL ("unsuppressed") should trigger adherence counseling and a follow-up VL; 2 consecutive unsuppressed VLs ("virologic failure") qualify for switching to second-line ART, with some exceptions. Here, we describe the pediatric VL cascade in Lesotho. Read More