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Interactions between chemicals and non-chemical stressors: The modifying effect of life events on the association between triclocarban, phenols and parabens with gestational length in a Puerto Rican cohort.

Sci Total Environ 2020 Mar 31;708:134719. Epub 2019 Oct 31.

Department of Environmental Health Sciences, University of Michigan, School of Public Health, Ann Arbor, MI, USA. Electronic address:

Background: Phenols and parabens are common additives to consumer products. There is evidence of adverse birth outcomes in association with prenatal exposure to these chemicals, in addition to psychosocial factors. We previously reported an increase in gestational length with bisphenol-A, methylparaben and propylparaben, and a decrease in gestational length with triclocarban. Read More

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Insights into the unique torpor of Botrylloides leachi, a colonial urochordate.

Dev Biol 2017 08 25;428(1):101-117. Epub 2017 May 25.

Israel Oceanographic and Limnological Research, National Institute of Oceanography, P.O. Box 8030, Tel Shikmona, Haifa 31080, Israel. Electronic address:

Rough environmental conditions make the survival of many multi-cellular organisms almost impossible, enforcing behavioral, morphological, physiological and reproductive rejoinders that can cope with harsh times and hostile environments, frequently through down-regulation of metabolism into basal states of dormancy, or torpor. This study examines one of the most unique torpor strategies seen within the phylum Chordata, exhibited by the colonial urochordate Botrylloides leachi, which enters a state of hibernation or aestivation in response to thermal stress, during which all of its functional colonial units (zooids) are entirely absorbed and the colony survives as small remnants of the vasculature, lacking both feeding and reproduction organs. Tissue vestiges then regenerate fully functional colony when re-exposed to milder environmental conditions. Read More

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Investigating the correlation between short-term effectiveness of VNS Therapy in reducing the severity of seizures and long-term responsiveness.

Authors:
Maryam Ravan

Epilepsy Res 2017 07 11;133:46-53. Epub 2017 Apr 11.

LivaNova PLC (formerly Cyberonics Inc), 100 Cyberonics Blvd, Houston, TX 77058, United States. Electronic address:

VNS (Vagus Nerve Stimulation) Therapy is an adjunctive therapy for patients with medically refractory epilepsy. The primary metric used to assess response to any treatment for epilepsy is seizure frequency reduction as measured using seizure diaries. In addition to seizure frequency, reduction in seizure severity is clinically meaningful to patients and can be measured objectively. Read More

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Rapid assessment of in vitro expanded human regulatory T cell function.

J Immunol Methods 2011 Sep 18;372(1-2):95-106. Epub 2011 Jul 18.

BD Biosciences, 2350 Qume Drive, San Jose, CA 95131, USA.

Human regulatory T cells (Treg) are able to actively suppress autoreactive immune responses. Phenotypically, they are broadly characterized as CD4+, CD25+, CD127(lo/⁻) and FoxP3+. CD45RA can be used to further differentiate the population into naïve (CD45RA(+)) and induced (CD45RA⁻) Treg. Read More

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September 2011
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