776 results match your criteria 2019 figo


The quality of intrapartum cardiotocography in preterm labour.

J Perinat Med 2021 Sep 20. Epub 2021 Sep 20.

Department of Obstetrics and Gynaecology, Amsterdam University Medical Centre Location VUmc, Amsterdam, The Netherlands.

Objectives: The aim of this study is to determine the quality of the foetal heart rate (FHR) recording, defined as signal loss, during preterm labour below 28 weeks gestational age (GA) and contribute to the discussion if cardiotocography (CTG) is of value for the extreme preterm foetus.

Methods: From January 2010 to December 2019 a retrospective study was conducted with data of 95 FHR recordings of singletons born between 24 and 28 weeks GA at the Amsterdam University Medical Centre, location VUmc. FHR tracings had a duration of at least 30 min and were obtained via external ultrasound mode. Read More

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September 2021

[Endocervical adenocarcinomas classified by International Endocervical Adenocarcinoma Criteria and Classification: a clinicopathological and prognostic analysis of 286 cases].

Zhonghua Bing Li Xue Za Zhi 2021 Sep;50(9):1014-1019

Department of Gynecological Oncology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310002, China.

To investigate the clinicopathological and prognostic significance of International Endocervical Adenocarcinoma Criteria and Classification (IECC) in classifying endocervical adenocarcinomas among Chinese women. A total of 286 endocervical adenocarcinomas diagnosed from January 2013 to December 2019 at the Women's Hospital, Zhejiang University School of Medicine were identified and included. The cases were reviewed and reclassified based on IECC. Read More

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September 2021

[Clinicopathological features of malignant mixed mesodermal tumor: analysis of 50 cases].

Zhonghua Bing Li Xue Za Zhi 2021 Sep;50(9):1008-1013

Department of Pathology, the Seventh Medical Center of PLA General Hospital, Beijing 100700, China.

To investigate the clinicpathological, immunohistochemical and molecular genetic features of malignant mixed mesodermal tumor (MMMT) in the female reproductive system. To analyze its histopathological characteristics, we performed a retrospective review of the MMMT cases diagnosed at PLA General Hospital, Beijing, China during 2005-2019 using its surgical and pathological databases. EnVision immunohistochemical staining was used to detect the expression of ER, PR, p16, p53 and MMR proteins. Read More

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September 2021

ConCerv: a prospective trial of conservative surgery for low-risk early-stage cervical cancer.

Int J Gynecol Cancer 2021 Sep 7. Epub 2021 Sep 7.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Objective: The objective of the ConCerv Trial was to prospectively evaluate the feasibility of conservative surgery in women with early-stage, low-risk cervical cancer.

Methods: From April 2010 to March 2019, a prospective, single-arm, multicenter study evaluated conservative surgery in participants from 16 sites in nine countries. Eligibility criteria included: (1) FIGO 2009 stage IA2-IB1 cervical carcinoma; (2) squamous cell (any grade) or adenocarcinoma (grade 1 or 2 only) histology; (3) tumor size 2 cm; (4) no lymphovascular space invasion; (5) depth of invasion 10 mm; (6) negative imaging for metastatic disease; and (7) negative conization margins. Read More

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September 2021

Vulvar cancer in Botswana in women with and without HIV infection: patterns of treatment and survival outcomes.

Int J Gynecol Cancer 2021 Sep 7. Epub 2021 Sep 7.

Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

Objectives: Vulvar cancer is a rare gynecological malignancy. However, the incidence of human papillomavirus (HPV)-associated vulvar disease is increasing, particularly in low- and middle-income countries. HIV infection is associated with an increased risk of HPV-associated vulvar cancer. Read More

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September 2021

Changes in gynecologic and breast cancer diagnoses during the first wave of the COVID-19 pandemic: analysis from a tertiary academic gyneco-oncological center in Germany.

Arch Gynecol Obstet 2021 Sep 7. Epub 2021 Sep 7.

Department of Obstetrics and Gynecology, University Hospital and CCC Munich, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.

Purpose: With the beginning of 2021, the world has been suffering from the COVID-19 pandemic for more than 1 year. More and more, we are able to evaluate side effects of the pandemic in the healthcare sector. A negative impact on cancer diagnoses is one of them. Read More

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September 2021

Radiomic Score as a Potential Imaging Biomarker for Predicting Survival in Patients With Cervical Cancer.

Front Oncol 2021 16;11:706043. Epub 2021 Aug 16.

Department of Radiology, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.

Objectives: Accurate prediction of prognosis will help adjust or optimize the treatment of cervical cancer and benefit the patients. We aimed to investigate the incremental value of radiomics when added to the FIGO stage in predicting overall survival (OS) in patients with cervical cancer.

Methods: This retrospective study included 106 patients with cervical cancer (FIGO stage IB1-IVa) between October 2017 and May 2019. Read More

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Friend or foe? The prognostic role of endometriosis in women with clear cell ovarian carcinoma. A UK population-based cohort study.

Arch Gynecol Obstet 2021 Sep 1. Epub 2021 Sep 1.

Department of Gynaecological Oncology, The Pan-Birmingham Gynaecological Cancer Centre, Sandwell and West Birmingham NHS Trust, Dudley Rd, Birmingham, B18 7QH, UK.

Purpose: The prognostic role of endometriosis amongst women with ovarian clear cell carcinoma (OCCC) remains debatable. The aim of this study was to ascertain the effect of endometriosis on the prognosis of OCCC.

Methods: A retrospective review of the medical records of 94 women diagnosed and treated for OCCC at a tertiary gynaecological cancer centre in the UK, spanning the period 2010-2019. Read More

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September 2021

Tumor stiffness measured by 3D magnetic resonance elastography can help predict the aggressiveness of endometrial carcinoma: preliminary findings.

Cancer Imaging 2021 Aug 28;21(1):50. Epub 2021 Aug 28.

Department of Radiology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.

Background: Preoperative evaluation of aggressiveness, including tumor histological subtype, grade of differentiation, Federation International of Gynecology and Obstetrics (FIGO) stage, and depth of myometrial invasion, is significant for treatment planning and prognosis in endometrial carcinoma (EC). The purpose of this study was to evaluate whether three-dimensional (3D) magnetic resonance elastography (MRE) can help predict the aggressiveness of EC.

Methods: From August 2015 to January 2019, 82 consecutive patients with suspected uterine tumors underwent pelvic MRI and MRE scans, and 15 patients with confirmed EC after surgical resection were enrolled. Read More

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Post-Conization FIGO stage IA1 squamous cell cervical carcinoma; is hysterectomy necessary?

Eur J Obstet Gynecol Reprod Biol 2021 Sep 8;264:368-373. Epub 2021 Aug 8.

Gynecology and Obstetrics Department, Women's and Children's University Hospital, Avda. Marítima del Sur s/n, Las Palmas de Gran Canaria 35016, Spain. Electronic address:

Objective: To compare and evaluate the results and suitability of two different approaches to the treatment of post-conization International Federation of Gynaecology and Obstetrics (FIGO) stage IA1 cervical carcinoma: a more radical approach, directly scheduling a second surgery versus a more conservative one, which consists of performing a cotest (PAP plus HPV-test) in a follow-up visit and deciding whether to apply a second surgery on the basis of the results.

Study Design: Retrospective descriptive study including 144 cases of stage IA1 cervical carcinoma diagnosed after a loop electrosurgical excisional procedure (conization), between 1987 and 2019 in the Mother-and-Child University Hospital of Gran Canaria (Spain). Selected patients were split into two groups for analysis: patients directly undergoing a second surgical intervention (hysterectomy or re-conization) after diagnosis and patients who were followed-up before making a decision whether to schedule a second surgery or continue to follow-up. Read More

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September 2021

Prognostic similarity between ovarian mucinous carcinoma with expansile invasion and ovarian mucinous borderline tumor: A retrospective analysis.

Medicine (Baltimore) 2021 Aug;100(32):e26895

Department of Obstetrics and Gynecology, National Defense Medical College Hospital, Saitama, Tokorozawa, Japan.

Abstract: There is a similarity of histological features and survival between ovarian mucinous carcinoma (MC) with expansile invasion and ovarian mucinous borderline tumor (MBT). The aim of this study was to compare the clinical outcomes of MC with expansile invasion with those of MBT based on the 2020 World Health Organization (WHO) criteria.A pathological review was performed on patients with MC, ovarian MBT, and seromucinous borderline tumors that underwent surgery at our hospital between 1984 and 2019. Read More

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Tumor Characteristic Variations between Symptomatic and Asymptomatic Endometrial Cancer.

Healthcare (Basel) 2021 Jul 16;9(7). Epub 2021 Jul 16.

Department of Gynecology and Obstetrics, University Hospital Brno, Masaryk University, 60177 Brno, Czech Republic.

Endometrial cancer is the most common gynecologic malignancy in Europe and usually diagnosed in its initial stage owing to early symptoms of abnormal bleeding. There is no population screening for this disease, although it can sometimes be accidentally diagnosed in asymptomatic patients. Our study aims to determine differences in clinical and tumor characteristics between an asymptomatic and symptomatic group of patients. Read More

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The complex relationship between infertility and female genital tract cancer: A review.

Urologia 2021 Aug 2:3915603211036426. Epub 2021 Aug 2.

Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Istituto di Ricovero e Cura a Carattere Scientifico, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.

Introduction: The link between female infertility and gynecological cancer has always been a debated and challenging topic. Although cervical cancer has the worst impact on female fertility, as it is usually diagnosed in patients of reproductive age, endometrial and ovarian cancer are also diagnosed and treated often in relatively younger patients in which fertility preservation is a relevant issue. The aim of this review is to highlight the correlation between therapy for female infertility and the developing cancer's risk and to describe the fertility sparing treatments in gynecological oncology. Read More

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Analysis of Factors Influencing Relapse and Pregnancy in Patients with Borderline Ovarian Tumors.

J Cancer 2021 2;12(17):5275-5285. Epub 2021 Jul 2.

Department of Gynecology and Obstetrics, Shengjing Hospital Affiliated of China Medical University, Shenyang, Liaoning, China.

This retrospective study analyzed the factors affecting recurrence in patients after surgery with borderline ovarian tumors and postoperative recurrence and pregnancy after fertility-sparing surgery (FSS), to provide guidance for clinical treatment of borderline ovarian tumors and propose a therapeutic strategy for fertility protection. A total of 415 patients with borderline ovarian tumors were initially operated on in the gynecology ward of Shengjing Hospital Affiliated with China Medical University from September 1, 2013, to September 1, 2019. Central pathology review and prospective follow-up were carried out. Read More

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Folinic acid rescue during methotrexate treatment for low-risk gestational trophoblastic neoplasia - How much is just right?

Gynecol Oncol 2021 Sep 13;162(3):638-644. Epub 2021 Jul 13.

New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Objective: To compare the outcomes of patients with low-risk gestational trophoblastic neoplasia (GTN) treated with 8-day methotrexate (MTX) with two different regimens of folinic acid (FA).

Methods: Retrospective cohort study of low-risk GTN followed at Rio de Janeiro Federal University, from January/2000-December/2019 with 8-day MTX with FA at 0.1 mg/kg versus 15 mg fixed dose. Read More

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September 2021

Radical hysterectomy without adjuvant radiotherapy in patients with cervix carcinoma FIGO 2009 IB1, with or without positive Sedlis criteria.

Gynecol Oncol 2021 Sep 10;162(3):539-545. Epub 2021 Jul 10.

Division of Gynaecological Oncology, Department of Gynaecology and Obstetrics, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium. Electronic address:

Introduction: Lymphovascular space invasion (LVSI), deep (>1/3) stromal invasion (DSI) and large tumor size (>4 cm) have been identified as predictors for intermediate risk for recurrence according to Sedlis (at least two of the prior risk factors) in FIGO stage I cervical cancer. Adjuvant radiotherapy (RT) has been advocated in these patients(1,2), but remains controversial.

Method: All consecutive patients (1997-2017) with cervical cancer FIGO (2009) stage IB1 (≤4 cm) were included. Read More

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September 2021

Imaging in gynecological disease: clinical and ultrasound characteristics of ovarian carcinosarcomas.

Ultrasound Obstet Gynecol 2021 Jul 5. Epub 2021 Jul 5.

Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.

Objectives: To describe the clinical and ultrasound characteristics of ovarian carcinosarcoma.

Methods: This is a retrospective multicenter study. From the International Ovarian Tumor Analysis (IOTA) database we identified 24 patients with a histological diagnosis of ovarian carcinosarcoma who had undergone preoperative ultrasound examination between 2010 and 2019. Read More

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The struggle against endometrial cancer: ten years of experience of a tertiary center.

Ginekol Pol 2021 Jun 22. Epub 2021 Jun 22.

Department of Obstetrics and Gynecology, Selcuk University Medicine Faculty, Selçuklu, Konya, Turkey.

Objectives: We aimed to investigate the clinical and pathological factors of our patients who were diagnosed with endometrial cancer in terms of prognosis. With this study, we present our 10 years of surgical experience in endometrial carcinoma cases.

Material And Methods: Four hundred twelve patients with endometrial carcinoma who applied to our center between 2010-2019 and that we followed up were evaluated retrospectively. Read More

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Predictors of chemotherapy resistance & relapse in gestational trophoblastic neoplasia.

Indian J Med Res 2020 Dec;152(6):595-606

Department of Obstetrics & Gynaecology, All India Institute of Medical Sciences, New Delhi, India.

Background & Objectives: Gestational trophoblastic neoplasia (GTN) is a chemosensitive malignancy with an excellent cure rate. The primary objective of the present study was to determine the predictors of chemoresistance and disease relapse, and the secondary objective was to appraise the WHO/FIGO risk scoring and course of disease in women with GTN.

Methods: In this retrospective study, case records of women treated for GTN from January 2011 to June 2019 were reviewed. Read More

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December 2020

Carcinosarcomas of the Uterus: Prognostic Factors and Impact of Adjuvant Treatment.

Cancer Manag Res 2021 10;13:4633-4645. Epub 2021 Jun 10.

Gynaecological Oncology, Royal Adelaide Hospital, Adelaide, Australia.

Background: Uncertainties remain about the most effective treatment for uterine carcinosarcoma (UCS), a rare but aggressive uterine cancer, due to the limited scope for randomized trials. This study investigates whether nodal excision or adjuvant therapies after hysterectomy offer a survival benefit, using multi-institutional clinical registry data from South Australia.

Methods: Data for all consecutive cases of UCS from 1980 to 2019 were extracted from the Clinical Cancer Registry. Read More

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Sentinel node biopsy for diagnosis of lymph node involvement in endometrial cancer.

Cochrane Database Syst Rev 2021 06 9;6:CD013021. Epub 2021 Jun 9.

Department of Gynaecological Oncology, GRACE Centre, Musgrove Park Hospital, Taunton, UK.

Background: Pelvic lymphadenectomy provides prognostic information for those diagnosed with endometrial (womb) cancer and provides information that may influence decisions regarding adjuvant treatment. However, studies have not shown a therapeutic benefit, and lymphadenectomy causes significant morbidity. The technique of sentinel lymph node biopsy (SLNB), allows the first draining node from a cancer to be identified and examined histologically for involvement with cancer cells. Read More

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Initial Ca 125 Value as a Predictive Marker for High-grade Serous Ovarian Cancer.

J Coll Physicians Surg Pak 2021 Jun;30(6):651-656

Department of Medical Oncology, Istanbul Medeniyet University, Goztepe Education and Research Hospital, Istanbul, Turkey.

Objective: To determine the relevance between the cut-off level of cancer antigen 125 (CA 125) level and long-term prognosis in high-grade serous ovarian cancer (HGSCs).

Study Design: Observational study.

Place And Duration Of Study: Departments of Oncology, Medeniyet University Goztepe Education and Research Hospital, and Kartal Lutfi Kirdar Education and Research Hospital, Istanbul, Turkey, from January 2017 to June 2019. Read More

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Risk of venous thromboembolism for ovarian cancer patients during first-line therapy after implementation of an Enhanced Recovery After Surgery (ERAS) protocol.

Gynecol Oncol 2021 Aug 3;162(2):353-359. Epub 2021 Jun 3.

Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States; Division of Gynecologic Oncology, Brigham and Women's Hospital, Boston, MA, United States; Dana-Farber Cancer Institute, Boston, MA, United States. Electronic address:

Objective: To determine incidence and risk factors for VTE for patients with advanced epithelial ovarian cancer undergoing first-line therapy, including cytoreductive surgery, on an Enhanced Recovery After Surgery (ERAS) protocol.

Methods: Medical records were reviewed for patients with FIGO stage IIIA-IVB epithelial ovarian, fallopian tube, or primary peritoneal cancer undergoing primary or interval cytoreductive surgery from March 2017 through September 2019. All patients were enrolled on an ERAS protocol, including 28-day postoperative VTE prophylaxis. Read More

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Five-fraction HDR brachytherapy in locally advanced cervical cancer: A monocentric experience.

Cancer Radiother 2021 Jul 19;25(5):463-468. Epub 2021 May 19.

Department of Radiotherapy, Lucien Neuwirth Cancer Institute, Saint-Priest en Jarez, France.

Purpose: The 5-fraction scheme (5×5-5.5Gy) is a common High-Dose Rate (HDR) intracavitary brachytherapy regimen for locally advanced cervical cancer (LACC). Yet, its equivalence with Pulse-Dose rate (PDR) schemes remains unproved. Read More

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[Using Immunohistochemical Markers and Clinicopathological Factors to Predict the Prognostic Survival of Different Types of Endometrial Cancer Recurrence].

Sichuan Da Xue Xue Bao Yi Xue Ban 2021 May;52(3):489-496

Department of Gynecology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400000, China.

Objective: To probe for factors that can be used effectively to predict the prognostic survival of patients with endometrial cancer recurrence.

Methods: The clinicopathological data of 473 patients with stage Ⅰ to Ⅲ endometrial cancer who underwent standard surgical treatment from October 2013 to May 2019 were retrospectively collected, and post-operative recurrence of the patients were followed up. Overall recurrence includes local recurrence and poor prognosis recurrence. Read More

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Adjuvant therapy and prognosis in uterine carcinosarcoma.

J Formos Med Assoc 2021 May 12. Epub 2021 May 12.

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Branch, and Chang Gung University College of Medicine, Taoyuan, Taiwan; Gynecologic Cancer Research Center, Chang Gung Memorial Hospital, Taiwan. Electronic address:

Purpose: To investigate the prognostic factors and impact of adjuvant treatment on uterine carcinosarcoma (UCS).

Methods: A retrospective review of UCS patients treated between 2005 and 2019 was conducted. International Federation of Gynecology and Obstetrics (FIGO) 2009 staging system was used. Read More

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Variables that prolong total operative time for robotic-assisted laparoscopic myomectomy: A 10-year tertiary hospital study in Korea.

Eur J Obstet Gynecol Reprod Biol 2021 Jul 4;262:62-67. Epub 2021 May 4.

Department of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

Study Objective: To identify factors that prolong total operative time (TOT) in robotic-assisted laparoscopic myomectomy (RALM).

Design: Retrospective cohort study.

Setting: Tertiary university hospital. Read More

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Potential prognostic factors in progression-free survival for patients with cervical cancer.

BMC Cancer 2021 May 10;21(1):531. Epub 2021 May 10.

Zhuhai Hospital of Traditional Chinese and Western Medicine, Zhuhai City, Guangdong, People's Republic of China.

Background: Cervical cancer continues to be one of the leading causes of cancer deaths among females in low and middle-income countries. In this study, we aimed to assess the independent prognostic value of clinical and potential prognostic factors in progression-free survival (PFS) in cervical cancer.

Methods: We conducted a retrospective study on 92 cervical cancer patients treated from 2017 to 2019 at the Zhuhai Hospital of Traditional Chinese and Western Medicine. Read More

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Placenta Accreta Spectrum: Correlation between FIGO Clinical Classification and Histopathologic Findings.

Am J Perinatol 2021 May 2. Epub 2021 May 2.

Department of Obstetrics and Gynecology, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.

Objective:  Placenta accreta spectrum (PAS) covers a wide spectrum of placental adherence/invasion with varied clinical significance. Histopathologic examination is considered the confirmatory gold standard, but is only obtained sometime after definitive treatment. The International Federation of Gynecology and Obstetrics (FIGO) has published a new clinical classification that can be assigned at delivery, and we aimed to investigate the association between this new FIGO classification and histopathology and also to assess its correlation with maternal outcomes. Read More

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Retrospective analysis of clinicopathological characteristics of 19 ovarian juvenile granulosa cell tumor cases.

J Obstet Gynaecol Res 2021 Jul 27;47(7):2492-2499. Epub 2021 Apr 27.

Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Aim: To describe the clinical and pathological characteristics, diagnosis, treatment, and outcomes of juvenile granulosa cell tumor (JGCT).

Methods: We retrospectively analyzed the data of 19 patients with histopathologically confirmed juvenile granulosa cell tumors treated in two medical centers in Wuhan city of China between 1999 and 2019.

Results: Totally, 19 patients were included during the period. Read More

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