36,154 results match your criteria 2018 editorial

Terminal augmented ureteroplasty with bladder onlay flap technique for recurrent distal ureteral stricture after ureteroneocystostomy: an initial case series.

Transl Androl Urol 2021 Aug;10(8):3332-3339

Department of Urology, Peking University First Hospital, Beijing, China.

Background: Bladder flap has been shown to be a feasible treatment for distal ureteral stenosis; this technique has been improved such that it can be used to address complex urinary tract obstructions. The purpose of the present study was to describe a surgical technique of ureteroplasty with a bladder onlay flap, which consists of a nontransecting and terminal augmented anastomosis, for repairing recurrent distal strictures of the ureter.

Methods: We retrospectively reviewed 6 patients who underwent this procedure between May 2018 and November 2019. Read More

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The human and health costs of failure to implement pro-Tiriti and pro-equity health policies: let's act as if we know this.

Peter Crampton

N Z Med J 2021 Sep 17;134(1542):8-10. Epub 2021 Sep 17.

Professor of Public Health, Kōhatu, Centre for Hauora Māori, University of Otago.

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September 2021

Update from the World Symposium on Pulmonary Hypertension 2018: does the new hemodynamic definition of pediatric pulmonary hypertension have an impact on treatment strategies?

Cardiovasc Diagn Ther 2021 Aug;11(4):1048-1051

Division of Pediatric Cardiology, University Children's Hospital Ulm, Ulm, Germany.

Pediatric pulmonary arterial hypertension (PAH) is a progressive life-threatening disease of the pulmonary vasculature and is defined as an elevation of the mean pulmonary arterial pressure. Before the 6th World Symposium on Pulmonary Hypertension (WSPH) in 2018, pulmonary hypertension (PH) used to be defined as a mean pulmonary artery pressure (mPAP) of ≥25 mmHg. On the WSPH a revised hemodynamic definition of PH was introduced lowering the threshold for a normal mPAP from <25 to <21 mmHg. Read More

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Diagnosis of visceral pleural invasion using confocal laser endomicroscopy during lung cancer surgery.

J Thorac Dis 2021 Aug;13(8):4742-4752

Department of Thoracic, Endocrine Surgery and Oncology, Tokushima University Graduate School of Biomedical Sciences, Kuramotocho, Tokushima, Japan.

Background: Visceral pleural invasion (VPI) in lung cancer is a significant prognostic factor; however, it is difficult to diagnose preoperatively or intraoperatively. In this study, we examined the possibility of intraoperative diagnosis of VPI using confocal laser endomicroscopy (CLE).

Methods: Among patients with primary lung cancer who underwent surgery between April 2018 and August 2019, those in whom the tumor was in contact with the pleura on chest computed tomography and whose pleural changes were intraoperatively confirmed were enrolled in this study. Read More

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Are functional outcomes and reoperation rates really better than those of cementless stems in displaced femoral neck fractures? An updated systematic review and meta-analysis of randomised controlled trials in current-generation stem designs.

J Chin Med Assoc 2021 Sep 9. Epub 2021 Sep 9.

Department of Orthopedic Surgery, Mackay Memorial Hospital, Taipei, Taiwan, ROC Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC Department of Surgery, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC Department of exercise and health science, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan, ROC.

Background: The study aim was to conduct a systematic review and meta-analysis to compare the functional outcomes and reoperation rates of cemented and cementless hip arthroplasty for treating displaced femoral neck fractures in elderly patients.

Methods: Systematic searches were conducted of literature up to December 2018 on PubMed, Embase, Cochrane, and Web of Science for randomised controlled trials (RCTs) concerning current-generation stem designs only. Two reviewers independently determined eligibility, extracted the outcome data and assessed the risk of bias of eligible studies. Read More

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September 2021

The burden of traumatic brain injury from low-energy falls among patients from 18 countries in the CENTER-TBI Registry: A comparative cohort study.

PLoS Med 2021 Sep 14;18(9):e1003761. Epub 2021 Sep 14.

Department of Neurosurgery, Antwerp University Hospital, Edegem, Belgium.

Background: Traumatic brain injury (TBI) is an important global public health burden, where those injured by high-energy transfer (e.g., road traffic collisions) are assumed to have more severe injury and are prioritised by emergency medical service trauma triage tools. Read More

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September 2021

The Performance of in 2020 and the Impact of COVID-19 on the Trend of Manuscript Submissions.

Malays J Med Sci 2021 Aug 26;28(4):1-4. Epub 2021 Aug 26.

Malaysian Journal of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

In this Editorial, we report on the trend of manuscript submissions during the peak of COVID-19 pandemic in 2020. The total monthly new manuscript submissions from 2018 to 2020 were compared to examine the overall trends in submission and publication activities. Apart from that, we also report on the changes in the journal's administration and the external recognition received by the journal. Read More

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Authors' correction for Euro Surveill. 2018;23(33).


Euro Surveill 2021 09;26(36)

European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.

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September 2021

A Phase II Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy, Safety, and Tolerability of Arbaclofen Administered for the Treatment of Social Function in Children and Adolescents With Autism Spectrum Disorders: Study Protocol for AIMS-2-TRIALS-CT1.

Front Psychiatry 2021 24;12:701729. Epub 2021 Aug 24.

Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Autism Spectrum Disorder (ASD or autism) is characterized by difficulties in social communication and interaction, which negatively impact on individuals and their families' quality of life. Currently no pharmacological interventions have been shown to be effective for improving social communication in autism. Previous trials have indicated the potential of arbaclofen for improving social function among autistic children and adolescents with fluent speech. Read More

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Computer-aided X-ray screening for tuberculosis and HIV testing among adults with cough in Malawi (the PROSPECT study): A randomised trial and cost-effectiveness analysis.

PLoS Med 2021 Sep 9;18(9):e1003752. Epub 2021 Sep 9.

Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.

Background: Suboptimal tuberculosis (TB) diagnostics and HIV contribute to the high global burden of TB. We investigated costs and yield from systematic HIV-TB screening, including computer-aided digital chest X-ray (DCXR-CAD).

Methods And Findings: In this open, three-arm randomised trial, adults (≥18 years) with cough attending acute primary services in Malawi were randomised (1:1:1) to standard of care (SOC); oral HIV testing (HIV screening) and linkage to care; or HIV testing and linkage to care plus DCXR-CAD with sputum Xpert for high CAD4TBv5 scores (HIV-TB screening). Read More

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September 2021

Primary Aortic Angiosarcoma: A Review of Two Cases Highlighting Unique Imaging and Clinical Characteristics.

Radiol Cardiothorac Imaging 2021 Aug 29;3(4):e210040. Epub 2021 Jul 29.

School of Medicine (C.H.K.), Department of Diagnostic Radiology (A.P.S.L., C.F.), Knight Cancer Institute (M.W., L.E.D.), and Department of Orthopaedics & Rehabilitation (K.R.G.), Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239; and Operative Care Division, Portland VA Medical Center, Portland, Ore (K.R.G.).

Angiosarcomas are rare vascular connective tissue tumors originating from the tunica intima, media, or adventitia and may arise in large vessels. Here two cases of primary angiosarcoma of the aorta are described that highlight initial manifestations and unique complications from diffuse arterial tumor emboli, which led to delayed cancer diagnosis. In patients with aortic lesions, imaging characteristics must be thoughtfully reconciled with clinical scenarios, particularly in patients with no additional evidence of atherosclerosis or vasculitis. Read More

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The driving forces behind the impressive progression of the journal of cell communication and signaling (JCCS).

Bernard Perbal

J Cell Commun Signal 2021 Sep 8. Epub 2021 Sep 8.

International CCN Society, Marseille, France.

The recent increase of the Journal of Cell Signaling and Communication' 2020 Impact Factor to 5.782, and its growing audience in the scientific community, provides an opportunity to step back and look at different aspects of this indicator's value. The take home message is that the top-ten major contributions to the 2020 ranking originated from North America and Europe followed by India with a high percentage of CCN-related publications and an excellent proportion of Editorial Board members' contributions to the Top10 best citations for the 2018-2019 period. Read More

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September 2021

Immunomodulating Therapy by Picibanil-based Imiquimod and Virotherapy for Advanced Uterine Cancer after Laparoscopic Surgery.

Gynecol Minim Invasive Ther 2021 Jul-Sep;10(3):191-194. Epub 2021 Aug 3.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Linkou Medical Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.

This is a case report of a uterine cancer with the International Federation of Gynecology and Obstetrics staging 3c2 with the initial clinical presentation of postmenopausal vaginal bleeding in August 2015. Endometrium biopsy showed invasive nests of poorly differentiated grade 3 endometrioid adenocarcinoma. The patient received robotic surgery including total hysterectomy, bilateral salpingo-oophorectomy, bilateral pelvic lymph node dissection, para-aortic lymph node dissection, and washing cytology. Read More

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Does the inability of CA1 area to respond to ischemia with early rapid adenosine release contribute to hippocampal vulnerability?: An Editorial Highlight for "Spontaneous, transient adenosine release is not enhanced in the CA1 region of hippocampus during severe ischemia models".

J Neurochem 2021 Sep 3. Epub 2021 Sep 3.

Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia.

This Editorial highlights a remarkable study in the current issue of the Journal of Neurochemistry in which Ganesana & Venton (2021) report new data showing that brain ischemia does not elicit transient adenosine release in the CA1 hippocampal area. Using fast-scan cyclic voltammetry at a carbon-fiber microelectrode implanted in the CA1 subfield of the hippocampus, it was shown that none of three different ischemia/reperfusion models could increase spontaneous, transient adenosine release, and more severe models even suppressed this presumably neuroprotective release. Since the authors have previously shown that in the caudate putamen, ischemia increased the frequency of spontaneous adenosine release (Ganesana & Venton, 2018), the new data may disclose a mechanism underlying important regional differences in rapid neuroprotective adenosine signaling. Read More

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September 2021

A critical appraisal of the quality of guidelines for radiation protection in interventional radiology using the AGREE II tool: A EuroAIM initiative.

Eur J Radiol 2021 Aug 19;143:109906. Epub 2021 Aug 19.

Department of Biomedical Sciences for Health, Università degli Studi di Milano, Via Mangiagalli 31, 20133 Milano, Italy; Unit of Radiology, IRCCS Policlinico San Donato, Via Rodolfo Morandi 30, San Donato Milanese, Italy. Electronic address:

Purpose: To systematically review and assess the methodological quality of guidelines for radiation protection in interventional radiology.

Materials And Methods: On April 15, 2021, a systematic search for guidelines on radiation protection in interventional radiology was performed using MEDLINE, EMBASE, National Guideline Clearinghouse, and National Institute for Health and Clinical Excellence databases. Among retrieved guidelines, we then excluded those not primarily focused on radiation protection or on interventional radiology. Read More

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When Pathobiont-Carbohydrate Interaction Turns Bittersweet!

Cell Mol Gastroenterol Hepatol 2021 Sep 1. Epub 2021 Sep 1.

Team "Mucosal microbiota in chronic inflammatory diseases," CNRS UMR 8104, INSERM U1016, Université de Paris, Paris, France. Electronic address:

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September 2021

How do Australian general practitioners spend their time? A cross-sectional analysis of Medicine in Australia: Balancing Employment and Life (MABEL) data examining 'non-billable workload'.

Aust J Gen Pract 2021 09;50(9):661-666

MBBS, FRACGP, MFM, PhD, Professor, Primary Care Research, Department of General Practice, Monash University, Vic; Director, Southern Academic Primary Care Research Unit, Faculty of Medicine, Nursing and Health Sciences, Monash University, Vic; Chair, Editorial Advisory Committee, Australian Journal of General Practice.

Background And Objectives: While Australian general practitioners (GPs) gain most of their income from direct patient interactions, they also spend time attending to professional or practice responsibilities. The aim of this study was to determine the time Australian GPs spend on work away from direct patient care ('non-billable work'), and practice and practitioner factors associated with non-billable work.

Method: This study was a cross-sectional analysis of GPs practising >7. Read More

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September 2021

Editorial: Secondary Metabolites and Peptides as Unique Natural Reservoirs of New Therapeutic Leads for Treatment of Cancer and Microbial Infections.

Front Chem 2021 12;9:748180. Epub 2021 Aug 12.

Department of Chemistry and Technology of Drugs, "Department of Excellence 2018-2022", Sapienza University, Rome, Italy.

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Pediatric and Adolescent Fractures of the Acetabulum treated with ORIF: What are their Functional Outcomes?

J Orthop Trauma 2021 Aug 24. Epub 2021 Aug 24.

Department of Orthopaedic Surgery, University of Cincinnati Academic Health Center, Cincinnati, Ohio, USA Division of Pediatric Orthopaedics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA Department of Orthopaedics, Orlando Health Orthopaedic Institute, Orlando, Florida, USA.

Objectives: To evaluate the functional outcomes of pediatric and adolescent patients (<18 years old) who sustained acetabulum fractures that were treated with open reduction internal fixation (ORIF).

Design: Retrospective cohort.

Setting: Level 1 trauma center. Read More

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The application of the "omental wrapping" technique with autologous onlay flap/graft ureteroplasty for the management of long ureteral strictures.

Transl Androl Urol 2021 Jul;10(7):2871-2878

Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, National Urological Cancer Center, Beijing, China.

Background: To present our experience with the "omental wrapping" technique in laparoscopic and robotic ureteroplasty using onlay flaps or grafts for the management of long proximal or middle ureteral strictures.

Methods: This is a retrospective review of 25 patients with long proximal or middle ureteral strictures who underwent laparoscopic and robotic onlay flaps or grafts ureteroplasty using an omental flap to reinforce an anastomosis site between August 2018 and November 2019. Perioperative and follow-up data were collected. Read More

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X-ray Dark-Field Chest Imaging: Qualitative and Quantitative Results in Healthy Humans.

Radiology 2021 Aug 24:210963. Epub 2021 Aug 24.

From the Department of Diagnostic and Interventional Radiology, School of Medicine & Klinikum Rechts der Isar, Technical University of Munich, Ismaningerstr 22, 81675 Munich, Germany (F.T.G., A.A.F., A.P.S., M.R.M., D.P., F.P.); Department of Physics and Munich School of BioEngineering, Technical University of Munich, Garching, Germany (T.U., M.F., K.W., W.N., P.B., R.S., F.P.); and Philips Research, Hamburg, Germany (T.K., J.v.B.).

Background X-ray dark-field radiography takes advantage of the wave properties of x-rays, with a relatively high signal in the lungs due to the many air-tissue interfaces in the alveoli. Purpose To describe the qualitative and quantitative characteristics of x-ray dark-field images in healthy human subjects. Materials and Methods Between October 2018 and January 2020, patients of legal age who underwent chest CT as part of their diagnostic work-up were screened for study participation. Read More

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A retrospective analysis of pancreas operations in children.

Transl Gastroenterol Hepatol 2021 25;6:39. Epub 2021 Jul 25.

The University of Texas Southwestern Medical Center, Dallas, TX, USA.

Background: Operative intervention for pediatric pancreas diseases is rare. Our goal is to gain a better understanding of the indications and outcomes relating to pancreas surgery in children. We hypothesized that these operations are safe and effective in this population. Read More

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The accuracy of clinical 3D printing in reconstructive surgery: literature review and validation study.

Gland Surg 2021 Jul;10(7):2293-2303

Department of Plastic, Reconstructive and Hand Surgery, Peninsula Health, Frankston, Victoria, Australia.

A growing number of studies demonstrate the benefits of 3D printing in improving surgical efficiency and subsequently clinical outcomes. However, the number of studies evaluating the accuracy of 3D printing techniques remains scarce. All publications appraising the accuracy of 3D printing between 1950 and 2018 were reviewed using well-established databases, including PubMed, Medline, Web of Science and Embase. Read More

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Applying plastic surgery principles to ovarian tissue transplantation.

Gland Surg 2021 Jul;10(7):2266-2274

Reproductive Services, Royal Women's Hospital, Parkville, VIC, Australia.

Ovarian tissue cryopreservation (OTC) and transplantation is an innovative procedure increasingly utilized to help preserve fertility after gonadotoxic treatments especially in cancer patients. Approximately 30% of autotransplanted patients are able to achieve live birth, typically with the help of in-vitro fertilization. Numerous techniques and grafting sites have been described to continue to increase this figure. Read More

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Value-based focused global population health management.

J Gastrointest Oncol 2021 Jul;12(Suppl 2):S275-S289

Thomas Jefferson College of Population Health, Philadelphia, PA, USA.

In 2018, approximately 18 million people worldwide were diagnosed with cancer and are predicted to double by 2040. The global quality chasm in improving health care worldwide requires "systems thinking" as the key to success. Aligning the goal around person-centered care captures the total needs of care of a population and not just disease categories. Read More

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Changes in children's lung function over two decades in relation to socioeconomic, parental and household factors in Wuhan, China.

J Thorac Dis 2021 Jul;13(7):4601-4613

Nicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, USA.

Background: It is important to identify risk and beneficial factors for children's lung function. This study aims to ascertain potential changes in children's lung function in relation to changes in socioeconomic, parental and household factors, based on a comparison between two periods spanning 25 years in Wuhan, the largest metropolis in central China.

Methods: In two cross-sectional studies, lung function measurements and questionnaire surveys were conducted on school-age children in 1993-1996 (Period I) and in 2018 (Period II). Read More

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Household environmental factors and children's respiratory health: comparison of two cross-sectional studies over 25 years in Wuhan, China.

J Thorac Dis 2021 Jul;13(7):4589-4600

School of Energy and Environmental Engineering, Beijing Key Laboratory of Resource-oriented Treatment of Industrial Pollutants, University of Science and Technology Beijing, Beijing, China.

Background: Over the recent decades, residential lifestyle and household environment have changed substantially with rapid development of industrialization and urbanization in China. Whether the prevalence of respiratory diseases changed is still lack of evidence. The objective of this study is to assess potential changes in children's respiratory disease prevalence and associated household environmental factors in Wuhan over a 25-year time interval. Read More

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The effects of indoor and outdoor air pollution on the prevalence of adults' respiratory diseases in four Chinese cities: a comparison between 2017-2018 and 1993-1996.

J Thorac Dis 2021 Jul;13(7):4560-4573

Global Health Research Center, Duke Kunshan University, Kunshan, China.

Background: Over the past decades, both ambient and household air pollution have changed in several aspects, including the emission sources and the concentrations of pollutants, in many Chinese cities. It is unknown whether these changes are associated with changes in health conditions, especially given changes in other factors due to rapid economic growth.

Methods: Two cross-sectional surveys were conducted in two periods spanning more than twenty years (1993-1996 . Read More

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