9,205 results match your criteria 2-year-old male

Case Report: Acute Kidney Failure due to Massive Envenomation of a Two-Year-Old Child Caused by Killer Bee Stings.

Am J Trop Med Hyg 2021 May 10. Epub 2021 May 10.

1Service de Médecine et Chirurgie Pédiatrique, Cayenne Hospital, Cayenne, French Guiana.

A hybrid species of Brazilian bee has proliferated on the South American continent since 1956. We describe a "killer bee" swarm attack on a 2-year-old girl in French Guiana. The patient weighed 10 kg, and approximately hundreds of bees' stingers were removed, that is, 10 stings/kg. Read More

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Posterior cranial vault distraction osteogenesis in the immunocompromised patient.

Childs Nerv Syst 2021 May 10. Epub 2021 May 10.

Division of Plastic Surgery, Department of Surgery, Children's of Mississippi, University of Mississippi Medical Center, 2500 State Street, Jackson, MS, 39216, USA.

Purpose: The treatment of patients with multisuture craniosynostosis is complex and patient-dependent. Cranial distraction osteogenesis is a relatively new procedure for treatment of these patients, with its use increasing in many centers. With this increased use comes an expanding range of indications. Read More

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[Mechanism of hepatocyte mitochondrial NDUFA13 deficiency-induced liver fibrogenesis: the role of abnormal hepatic stellate cell activation].

Nan Fang Yi Ke Da Xue Xue Bao 2021 Apr;41(4):529-535

Pediatrics Research Institute, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; China International Science and Technology Cooperation Base of Child Development and Critical Disorders; Chongqing Key Laboratory of Child Infection and Immunity, Chongqing 400014, China.

Objective: To investigate the role of hepatocyte mitochondrial NDUFA13 loss in the liver fibrogenesis in mice and explore the possible mechanisms.

Objective: We used liver-specific NDUFA13 heterozygous knockout mouse models (NDUFA13; Alb-Cre) established previously by intercrossing NDUFA13 and Alb-Cre mice, with their littermate control NDUFA13 mice as the control (=8). The mice were euthanized at the age of 4 weeks and 2 years, and the liver tissues were collected for HE and Masson staining to observe the pathological changes and fibrosis phenotypes. Read More

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Seromucinous hamartoma of ethmoid sinus in pediatric patient (case report).

Int J Surg Case Rep 2021 Apr 27;82:105915. Epub 2021 Apr 27.

Dar AlUloom University, Riyadh, Saudi Arabia.

Introduction And Importance: Seromucinous hamartoma is a rare benign glandular proliferation arising from the respiratory epithelium, which was originally described by Baillie and Batsakis in 1974. Since this time, case reports started to be published on SH, as a middle aged and elderly disease, here we report a case of a pediatric patient who found to have SH.

Presentation Of The Case: 2-year-old girl, brought by her parent with a complain of a mass at the right medial canthal area for one year. Read More

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Evolving Peri-Anal Mass in 2-Year-Old.

Pediatr Infect Dis J 2020 Sep;39(9):873

From the Division of Medical Education, Department of Pediatrics, UT Southwestern Medical Center, Dallas, Texas.

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September 2020

Identification of a novel homozygous mutation in the gene from a patient with spondylo-meta-epiphyseal dysplasia by whole exome sequencing.

Iran J Basic Med Sci 2021 Feb;24(2):191-195

Ariagene Medical Genetics Laboratory, Mahmoudnejad Ave, Qom, Iran.

Objectives: The spondylo-meta-epiphyseal dysplasia (SMED) short limbs-hand type is a rare autosomal recessive disease, which is characterized by premature calcification leading to severe disproportionate short stature and various skeletal changes. Defective function of a conserved region encoding discoidin domain receptor tyrosine kinase 2 (DDR2 protein) by the discoidin domain-containing receptor 2 ( gene) is cause of this disease. The purpose of present study was to investigate disease-causing mutations on gene in an Iranian family with SMED, and predict the DDR2 protein molecular mechanism in development of SMED. Read More

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February 2021

Choroid plexus cyst causing acute hydrocephalus and transtentorial herniation: report of a rare case and its successful neuroendoscopic treatment.

Childs Nerv Syst 2021 May 4. Epub 2021 May 4.

Neurosurgery Department, Garrahan Hospital, Buenos Aires, Argentina.

Choroid plexus cysts (CPC) are a frequent incidental neuroimaging finding and completely asymptomatic in the vast majority of cases. We hereby describe a rare case of acute hydrocephalus secondary to a CPC, atypical in size, location and presentation, which required urgent neuroendoscopic management. There are very few reported cases of CPC causing obstructive hydrocephalus. Read More

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Aural polyp with facial asymmetry in an unfortunate infant.

Malays Fam Physician 2021 Mar 8;16(1):133-135. Epub 2021 Feb 8.

Department of Otorhinolaryngology, Hospital Tuanku Jaafar, Seremban Negeri Sembilan, Malaysia.

Temporal bone rhabdomyosarcoma is an aggressive entity that simulates chronic otitis ear infection. It is the most common soft tissue sarcoma amongst pediatric patients. Herein, we would like to report a case of temporal bone rhabdomyosarcoma involving a 2-year-old boy who presented with a one-month history of otorrhea with facial asymmetry. Read More

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Pediatric cerebral stroke induced by Epstein-Barr virus infection: Role of Interelukin overexpression.

Acta Biomed 2021 Apr 30;92(S1):e2021135. Epub 2021 Apr 30.

Institute of Pediatrics, Fondazione Policlinico A. Gemelli IRCCS - Università Cattolica Sacro Cuore, Rome, Italy .

Introduction: Ischemic stroke is an important cause of death and long-term morbidity in children. Viral respiratory infections are emerging as important risk factors for ischemic stroke in this age group of patients. Direct action of virus against cerebral vessels, autoimmune reactivity, and an increased production of cytokines have all been advocated as main factors in determining ischemic stroke. Read More

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Occurrence of Canker and Wood Rot Pathogens on Stone Fruit Propagation Material and Nursery Trees in the Western Cape of South Africa.

Plant Dis 2021 May 4. Epub 2021 May 4.

Stellenbosch University, Plant Pathology, Private BagX1, Matieland, Stellenbosch, Western Cape, South Africa, 7602.

Dieback and canker of young stone fruit trees can cause suboptimal growth and even death under severe conditions. One source of inoculum of canker pathogens could be through nursery trees harboring latent infections that would not be visible to inspections done according to the deciduous fruit scheme. The objectives of this study were to identify the canker and wood rot fungal pathogens present in nursery stone fruit trees as well as propagation material and to evaluate their pathogenicity. Read More

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Infants recognize words spoken through opaque masks but not through clear masks.

Dev Sci 2021 May 3. Epub 2021 May 3.

Department of Psychological and Brain Sciences, University of Delaware, Newark, Delaware, USA.

COVID-19 has modified numerous aspects of children's social environments. Many children are now spoken to through a mask. There is little empirical evidence attesting to the effects of masked language input on language processing. Read More

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Pulmonary mass-like lesion caused by Toxoplasma gondii in a domestic shorthair cat.

J Vet Intern Med 2021 May 4. Epub 2021 May 4.

Dublin, Ireland.

A 2-year-old male neutered domestic shorthair cat underwent investigations for acute onset of lethargy, hyporexia, and cough. Computed tomography of the thorax identified a large mass-like lesion in the left cranial lung lobe and bilateral pleural effusion. Thoracotomy and left cranial lung lobectomy were performed. Read More

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Kawasaki Disease with Mild Encephalitis/Encephalopathy with Reversible Splenial Lesion in a 2-Year-Old Girl.

Indian J Pediatr 2021 May 3. Epub 2021 May 3.

Department of Pediatrics, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi, 321-0293, Japan.

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The role of magnesium in the management of acute and long-term symptoms caused by tetanus in two dogs.

Top Companion Anim Med 2021 Apr 29:100535. Epub 2021 Apr 29.

Companion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Tetanus in dogs is a relatively uncommon neurological disease caused by the sporogenic bacillus Clostridium tetani. This disease is associated with prolonged hospitalization and mortality rates from 8-50%. A 2-year-old, neutered male King Charles Spaniel and an approximately 8- months-old female Mongrel dog presented to Companion Animal Clinic with symptoms of muscle rigidity and generalized stiffness. Read More

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A 2-Year-Old Girl with Multisystem Inflammatory Syndrome in Children (MIS-C).

R I Med J (2013) 2021 May 3;104(4):49-52. Epub 2021 May 3.

Associate Professor of Emergency Medicine, Clinician Educator; Associate Professor of Pediatrics, Clinician Educator, Alpert Medical School of Brown University, Providence, RI.

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Antioxidation Defenses of Queens and Workers Respond to Imidacloprid in Different Age-Dependent Ways: Old Queens Are Resistant, Foragers Are Not.

Animals (Basel) 2021 Apr 26;11(5). Epub 2021 Apr 26.

Department of Zoology and Animal Ecology, Faculty of Environmental Biology, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland.

We investigated how different antioxidant defenses (ADSs) were shaped by evolution in young/old workers and queens to broaden the limited knowledge on whether ADSs are effective in contemporary pesticide environments and to complete bee oxidative-aging theory. We acquired 1-day-old, 20-day-old, and 2-year-old queens and 1-day-old and 20-day-old workers (foragers) fed 0, 5, or 200 ppb imidacloprid, a pesticide oxidative stressor. The activities of catalase, glutathione peroxidase, glutathione S-transferase, and superoxide dismutase and the level of total antioxidant potential were determined in hemolymph. Read More

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Compound Haplotype Variants in and Genes Determine Clinical Outcome of Atypical Hemolytic Uremic Syndrome (aHUS)-A Series of Cases from a Single Family.

J Pers Med 2021 Apr 15;11(4). Epub 2021 Apr 15.

Warsaw Genomics INC, 01-682 Warsaw, Poland.

Atypical hemolytic uremic syndrome (aHUS) is a rare disease triggered by dysregulation of the alternative complement pathway, consisting of a characteristic triad of nonimmune hemolytic anemia, thrombocytopenia, and renal failure. The risk of aHUS onset, recurrence, and allograft loss depends on the genetic background of a patient. We show a series of cases from a single family whose five members were affected by aHUS and presented distinct clinical outcomes. Read More

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A Pilot Study Using Accelerometers to Characterise the Licking Behaviour of Penned Cattle at a Mineral Block Supplement.

Animals (Basel) 2021 Apr 17;11(4). Epub 2021 Apr 17.

Ruminant Research Group (RRG), School of Environmental and Rural Science, University of New England, Armidale, NSW 2351, Australia.

Identifying the licking behaviour in beef cattle may provide a means to measure time spent licking for estimating individual block supplement intake. This study aimed to determine the effectiveness of tri-axial accelerometers deployed in a neck-collar and an ear-tag, to characterise the licking behaviour of beef cattle in individual pens. Four, 2-year-old Angus steers weighing 368 ± 9. Read More

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Multi-directional Cranial Distraction Osteogenesis for Treating Sagittal Synostosis with Frontometaphyseal Dysplasia: A Case Report.

Plast Reconstr Surg Glob Open 2021 Apr 23;9(4):e3551. Epub 2021 Apr 23.

Department of Plastic Surgery, Jichi Children's Medical Center Tochigi, Jichi Medical University, Tochigi, Japan.

Frontometaphyseal dysplasia (FMD), also known as Gorlin-Cohen syndrome, is a rare genetic syndrome. This syndrome affects the skeletal system and connective tissue, and causes a wide spectrum of manifestations of the skull, tubular bones, cardiovascular system, urinary system, and/or gastrointestinal system. Craniofacial findings of FMD are characterized by protruding supraorbital ridge, broad nasal bridge, hypertelorism, down-slanting palpebral fissures, and/or micrognathia. Read More

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[Case report: death of a 2-year-old girl with postmortem diagnosis of a rare coronary artery vasculitis typical for Kawasaki syndrome].

Rechtsmedizin (Berl) 2021 Apr 23:1-5. Epub 2021 Apr 23.

Institut für Rechtsmedizin, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Deutschland.

Coronary artery autoimmune vasculitis (Kawasaki syndrome) is at least in Germany a very rare condition, that typically manifests in childhood. The symptoms are often unspecific and complications with vascular aneurysms, thrombosis and myocardial infarction can occur. Multiple cases of Kawasaki-like symptoms in children with positive SARS-CoV‑2 test results have been reported during the course of the COVID-19 pandemic the past year. Read More

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Optimizing heartworm diagnosis in dogs using multiple test combinations.

Parasit Vectors 2021 Apr 26;14(1):224. Epub 2021 Apr 26.

Maddie's Shelter Medicine Program, College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, Gainesville, FL, 32610, USA.

Background: Various heartworm (HW) diagnostic testing modalities detect products of, or reactions to, different life cycle stages of Dirofilaria immitis. Microfilariae (Mf) can be directly visualized in blood, antigen (Ag) from immature and adult heartworms may be detected on commercial assays, and antibody (Ab) tests detect the host immune response to larval stages. Ag and Mf tests are commonly used in dogs, which frequently carry adult HW infections, but Ab tests have only been validated for use in cats. Read More

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Case Report: Application and Limitations of a Plant-Based Diet Formulated for a Cat With Feline Lower Urinary Tract Disease.

Front Vet Sci 2021 9;8:658265. Epub 2021 Apr 9.

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

A 2-year-old male castrated domestic shorthair cat was presented for recommendations for dietary management of chronic FLUTD using a strictly plant-based diet as per the stipulations of the cat's owner. The cat had a history of urethral obstruction of unknown etiology, persistent marked struvite crystalluria, and persistent inappropriate elimination. Commercial plant-based products meeting the nutritional recommendations for maintenance of adult cats with the lowest concentration of struvite precursors were identified, but the cat would not eat them. Read More

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A-scan biometry, phacoemulsification, and foldable intraocular lens implantation in a young orangutan ().

Open Vet J 2021 Jan-Mar;11(1):121-127. Epub 2021 Feb 13.

Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand.

Background: Cataracts are the major cause of visual impairment in animals which can be curable by surgical treatment. Phacoemulsification is the standard technique for cataract treatment that is applied to almost all species with a high success rate.

Case Description: A 2-year-old intact female orangutan () was presented for the study having bilateral opacity of the lenses, for 2 weeks. Read More

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February 2021

A novel heterozygous mutation in the SLC5A2 gene causing severe glycosuria, mild failure to thrive, and subclinical hypoglycemia.

J Diabetes 2021 Apr 24. Epub 2021 Apr 24.

Endocrine Unit, Second Department of Obstetrics and Gynecology, Aretaieion Hospital, Medical School, University of Athens, Athens, Greece.

Highlights A novel heterozygous mutation in the SLC5A2 gene in a 2-year-old girl with severe asymptomatic glycosuria, mild failure to thrive, and subclinical hypoglycemia: Continuous glucose monitoring identified 14% hypoglycemic excursions (< 70 mg/dl), reduced at 1% with 1 g/Kg uncooked cornstarch at bed-time milk and eliminated (0%) adjusting the dose at 1.5 g/Kg, as shown by Flash technology. Read More

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Laparoscopic transposition for crossing vessels (vascular hitch) in pure extrinsic pelvic-ureteric junction obstruction: a successful case report of a 2-year-old infant with horseshoe kidney.

Surg Case Rep 2021 Apr 23;7(1):103. Epub 2021 Apr 23.

Department of Pediatric Surgery, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.

Background: Pediatric hydronephrosis induced by pelvic-ureteric junction obstruction (PUJO) is treated by dismembered pyeloplasty (DP) via open and laparoscopic surgery. The etiology of PUJO involves both intrinsic stenosis and extrinsic compression of crossing vessels (CVs). PUJO owing to CVs is also treated by DP, as there is no consensus concerning this vascular condition. Read More

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Cholangiojejunostomy for multiple biliary ducts in living donor liver transplantation: A case report.

World J Clin Cases 2021 Apr;9(11):2649-2654

Clinical Center for Pediatric Liver Transplantation, Capital Medical University, Beijing 100050, China.

Background: Laparoscopic living donor hepatectomy (LLDH) has been successfully carried out in several transplant centers. Biliary reconstruction is key in living donor liver transplantation (LDLT). Reliable biliary reconstruction can effectively prevent postoperative biliary stricture and leakage. Read More

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Heterozygous missense variant in TRPC6 in a boy with rapidly progressive infantile nephrotic syndrome associated with diffuse mesangial sclerosis.

Am J Med Genet A 2021 Apr 21. Epub 2021 Apr 21.

Department of Medical Genetics, Shinshu University School of Medicine, Matsumoto, Japan.

Transient receptor potential channel C6 encoded by TRPC6 is involved in slit diaphragm formation in podocytes, and abnormalities of the TRPC6 protein cause various glomerular diseases. The first identified pathogenic variant of TRPC6 was found to cause steroid-resistant nephrotic syndrome that typically developed in adulthood and then slowly led to end-stage renal disease, along with a renal pathology of focal segmental glomerulosclerosis. Here, we report a patient with rapidly progressing infantile nephrotic syndrome and a heterozygous missense TRPC6 variant. Read More

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A Clinical Diagnosis of Wiskott Aldrich Syndrome in an Ethiopian Boy with Recurrent Sinopulmonary Infections: A Case Report.

Ethiop J Health Sci 2020 Nov;30(6):1051-1054

St. Paul's Hospital and Millennium Medical College, Addis Ababa, Ethiopia.

Background: Wiskott Aldrich syndrome is a primary immunodeficiency notable for eczema, recurrent infections, bleeding diathesis and microcytic thrombocytopenia.

Case: A 4½ year old boy presented with recurrent sinopulmonary infections, repeated treatment for severe eczema since infancy, thrombocytopenia with low platelet volume. His brother and uncles died during childhood due to repeated illnesses. Read More

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November 2020

Pseudomembranous laryngotracheobronchitis due to coinfection with human bocavirus 1 and Mycoplasma pneumoniae: a case report.

Transl Pediatr 2021 Mar;10(3):673-678

Department of Children's Respiratory Disease, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.

Pseudomembranous laryngotracheobronchitis is rarely reported yet potentially life-threatening infectious cause of airway obstruction in children. The causative organisms of this condition are often considered to promote bacterial superinfection following viral infection. We report a case of pseudomembranous laryngotracheobronchitis in a patient caused by human bocavirus 1 and (). Read More

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Erratum to: Health of 2-year-old children born after vitrified oocyte donation in comparison with peers born after fresh oocyte donation.

Hum Reprod Open 2021 13;2021(2):hoab013. Epub 2021 Apr 13.

Centre for Medical Genetics, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.

[This corrects the article DOI: 10.1093/hropen/hoab002.]. Read More

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