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Duplicated Middle Cerebral Artery Aneurysms Treated by Coil Embolization; A Report of Two Cases and Literature Review.

J Stroke Cerebrovasc Dis 2021 Apr 14;30(7):105773. Epub 2021 Apr 14.

Department of Neurosurgery, Nara Medical University, Kashihara, Japan. Electronic address:

Background: Duplication of the middle cerebral artery (DMCA) is an anomalous vessel arising from the internal carotid artery (ICA). Aneurysms at the origin of a DMCA have been reported; however, most have been treated with clipping surgery. Here, we describe two cases of aneurysms at the origin of a DMCA treated with coil embolization. Read More

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Injectable tricalcium phosphate/calcium sulfate granule enhances bone repair by reversible setting reaction.

Biochem Biophys Res Commun 2021 Apr 14;557:151-158. Epub 2021 Apr 14.

Department of Engineering Sciences: Applied Materials Sciences, The Ångström Laboratory, SE-751 21, Uppsala, Sweden. Electronic address:

Towards repairing bone defects, calcium sulfate and calcium phosphate cement have been recognized as promising bone grafts. However, the current bone cements are generally lack of proper porosity for cell migration and new tissue formation. On the other hand, porous scaffold cannot be delivered by injection, which limits its use its clinical use. Read More

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Limb dominance influences energy absorption contribution (EAC) during landing after anterior cruciate ligament reconstruction.

Phys Ther Sport 2021 Apr 5;50:42-49. Epub 2021 Apr 5.

Elite Orthosport Physical Therapy and Performance, 12121 Wilshire Blvd, Unit 100, Los Angeles, CA, 90025, USA.

Objective: To determine the role of limb dominance on energy absorption contribution (EAC) during a jump landing (JL) task at return to sport (RTS) after ACL-R.

Design: Cross-sectional study.

Setting: Clinical Research Laboratory. Read More

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A longitudinal investigation of landing biomechanics following anterior cruciate ligament reconstruction.

Phys Ther Sport 2021 Mar 31;50:36-41. Epub 2021 Mar 31.

School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Australia; OrthoSport Victoria Research Unit, Melbourne, Australia.

Objective: Abnormal movement patterns have been shown during landing in patients who have undergone anterior cruciate ligament (ACL) reconstruction surgery. The purpose of this study was to investigate landing biomechanics over time in this patient group to determine whether asymmetry between limbs reduced with time and after a return to physical activity.

Design: Prospective longitudinal study. Read More

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Trends in substances involved in polysubstance overdose fatalities in Maryland, USA 2003-2019.

Drug Alcohol Depend 2021 Apr 12;223:108700. Epub 2021 Apr 12.

Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD, 21205, USA.

Background: The substances driving the overdose epidemic in the United States have changed over time. Since 2013, fentanyl-analogues have become the primary opioids driving the epidemic. Recently, polysubstance related deaths have come to the forefront of the epidemic. Read More

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High-field solution state DNP using cross-correlations.

J Magn Reson 2021 Feb 18;326:106940. Epub 2021 Feb 18.

School of Chemistry, University of Southampton, Southampton, UK. Electronic address:

At the magnetic fields of common NMR instruments, electron Zeeman frequencies are too high for efficient electron-nuclear dipolar cross-relaxation to occur in solution. The rate of that process fades with the electron Zeeman frequency as ω - in the absence of isotropic hyperfine couplings, liquid state dynamic nuclear polarisation (DNP) in high-field magnets is therefore impractical. However, contact coupling and dipolar cross-relaxation are not the only mechanisms that can move electron magnetisation to nuclei in liquids: multiple cross-correlated (CC) relaxation processes also exist, involving various combinations of interaction tensor anisotropies. Read More

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February 2021

Upper airway stimulation: Fewer complications, ED presentations, readmissions, and increased surgical success.

Am J Otolaryngol 2021 Apr 7;42(5):103035. Epub 2021 Apr 7.

Thomas Jefferson University Hospital, Department of Otolaryngology - Head and Neck Surgery, 925 Chestnut St, Philadelphia, PA 19107, United States of America.

Objectives: Evaluate the rate of complications, readmissions, emergency department presentations, and surgical success rates amongst three standard surgical treatment options for obstructive sleep apnea: upper airway stimulation, transoral robotic surgery, and expansion sphincter pharyngoplasty.

Study Design: Retrospective cohort.

Setting: Tertiary care center. Read More

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Early enteral nutrition and factors related to in-hospital mortality in people on extracorporeal membrane oxygenation.

Nutrition 2021 Feb 28;89:111222. Epub 2021 Feb 28.

Department of Thoracic and Cardiovascular Surgery, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea. Electronic address:

Objectives: There are concerns about adverse events related to early enteral nutrition (EN) in people receiving extracorporeal membrane oxygenation (ECMO). This was a retrospective study evaluating. This nutritional support of people receiving ECMO, factors that may confer benefits in outcomes. Read More

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February 2021

Use of academic electronic medical records in nurse education: A scoping review.

Nurse Educ Today 2021 Apr 9;101:104889. Epub 2021 Apr 9.

School of Nursing and Midwifery, La Trobe University, Bundoora, Victoria 3086, Australia.

Background: Use of academic electronic medical records is internationally recognised as a means for preparing health professional students for the digital healthcare environment. Reported practice benefits include skills for electronic documentation, health informatics, point-of-care clinical decision support systems, as well as preparation for information technology-enabled clinical settings, while challenges include lack of access to simulation software, faculty-related barriers, limited finances and educational software costs. However, little is known about best practices related to its use within pre-licensure or entry-to-practice nursing curricula and impact on clinical practice outcomes. Read More

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Nursing applicants' reasoning skills and factors related to them: A cross-sectional study.

Nurse Educ Today 2021 Apr 9;101:104890. Epub 2021 Apr 9.

Department of Nursing Science, Hospital District of Satakunta, 20014 University of Turku, Finland. Electronic address:

Background: The assessment of reasoning skills is recommended in undergraduate nursing student selection. Reasoning skills are crucial for sound decision-making, improving patient safety and are necessary from the very beginning of studies. Nursing applicants' reasoning skills based on the reasoning process have not been previously measured. Read More

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Towards standardization of lymph-node ratio classifications: Validation and comparison of different lymph node ratio classifications for predicting prognosis of patients with resected gastric cancer.

Ann Diagn Pathol 2021 Mar 31;52:151738. Epub 2021 Mar 31.

Complutense University of Madrid, Av. Séneca 2, 28040 Madrid, Spain; Hospital General Universitario Gregorio Marañón, c/ Dr. Esquerdo n° 46, 28007 Madrid, Spain.

Introduction: The TNM staging system is the main prognostic tool for GC, but the number of metastatic lymph nodes (LN) can be affected by surgical, pathological, tumor or host factors. Several authors have shown that lymph node ratio (LNR) may be superior to TNM staging in GC. However, cut-off values vary between studies and LNR assessment is not standardized. Read More

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Placenta pathology in recipient versus donor oocyte derivation for in vitro fertilization in a setting of hypertensive disorders of pregnancy and IUGR.

Placenta 2021 Mar 23;108:114-121. Epub 2021 Mar 23.

Department of Pathology, University of Ottawa, Children's Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON K1H 8L1, Canada. Electronic address:

Introduction: Assisted reproductive technology including in vitro fertilization (IVF) and oocyte donation (OD) may increase risk for placenta-mediated diseases. Comprehensive analysis of histopathological placental lesions according to source of oocytes used in the IVF procedure - recipient derived (RD-IVF) vs oocyte donation (OD-IVF), has not been conducted in a population with a hypertensive disorder of pregnancy (HDP) and/or intrauterine growth restriction (IUGR).

Methods: A retrospective cohort study of archived placenta specimens from RD-IVF and OD-IVF pregnancies affected by HDP and/or IUGR was conducted with blinded histopathological placental examination. Read More

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Screening of tick-borne pathogens in argasid ticks in Zambia: Expansion of the geographic distribution of Rickettsia lusitaniae and Rickettsia hoogstraalii and detection of putative novel Anaplasma species.

Ticks Tick Borne Dis 2021 Apr 5;12(4):101720. Epub 2021 Apr 5.

Laboratory of Parasitology, Graduate School of Infectious Diseases, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan. Electronic address:

Ticks (Ixodidae and Argasidae) are important arthropod vectors of various pathogens that cause human and animal infectious diseases. Many previously published studies on tick-borne pathogens focused on those transmitted by ixodid ticks. Although there are increasing reports of viral pathogens associated with argasid ticks, information on bacterial pathogens they transmit is scarce. Read More

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Evaluation of pedestrian critical gap and crossing speed at midblock crossing using image processing.

Accid Anal Prev 2021 Apr 14;156:106127. Epub 2021 Apr 14.

University of Central Florida, Department of Civil & Environmental and Construction Engineering, Orlando, FL, 32816, USA.

Pedestrians confront risky situations at midblock sections due to the unyielding behavior of drivers. Thus, pedestrians have to wait for an appropriate gap to cross. This research investigates pedestrians' gap acceptance and crossing speed for midblock crossings by image processing methods in Izmir, Turkey. Read More

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Glycerol as a substrate for actinobacteria of biotechnological interest: Advantages and perspectives in circular economy systems.

Chemosphere 2021 Apr 7;279:130505. Epub 2021 Apr 7.

Planta Piloto de Procesos Industriales Microbiológicos (PROIMI-CONICET), Avenida Belgrano y Pasaje Caseros, 4000, San Miguel de Tucumán, Tucumán, Argentina; Facultad de Ciencias Naturales e Instituto Miguel Lillo, Universidad Nacional de Tucumán, Miguel Lillo 205, 4000, Tucumán, Argentina. Electronic address:

Actinobacteria represent a ubiquitous group of microorganisms widely distributed in ecosystems. They have diverse physiological and metabolic properties, including the production of extracellular enzymes and a variety of secondary bioactive metabolites, such as antibiotics, immunosuppressants, and other compounds of industrial interest. Therefore, actinobacteria have been used for biotechnological purposes for more than three decades. Read More

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Disentangling Cognitive Heterogeneity in Psychotic Spectrum Disorders.

Asian J Psychiatr 2021 Apr 6;60:102651. Epub 2021 Apr 6.

Department of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Neuropsychological impairments represent a central feature of psychosis-spectrum disorders. It is characterized by a great both within- and between-subjects variability (i.e. Read More

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Dynamic characteristics of microbial community and soluble microbial products in partial nitrification biofilm system developed from marine sediments treating high salinity wastewater.

J Environ Manage 2021 Apr 14;290:112586. Epub 2021 Apr 14.

School of Civil Engineering, Shandong University, Jinan, Shandong, 250002, China. Electronic address:

High salinity wastewater generally resulted in microorganism death and low treatment efficiency of nutrient in conventional activity sludge system. Marine sediments, containing a huge amount of natural salt-tolerant microorganisms, provide a feasible option for the rapid construction of halophilic biological treatment system. However, the dynamic of native microorganisms and the fate of soluble microbial products (SMP) in halophilic biofilm system developed from marine sediments needs to be further studied. Read More

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COgnitive enhancement and consumption of psychoactive Substances among Youth Students (COSYS): a cross-sectional study in France.

Public Health 2021 Apr 14;194:75-78. Epub 2021 Apr 14.

Addictovigilance Center, Fernand-Widal Hospital, Paris, France. Electronic address:

Objectives: This descriptive and analytical study investigated the consumption rates of psychoactive substances among individuals aged 18-25 years in France. More specifically, it enabled assessment of the extent of the neuroenhancement (NE) phenomenon among students in France (including study of the misuse of psychostimulant medicines).

Study Design: COgnitive enhancement and consumption of psychoactive Substances among Youth Students (COSYS) is a cross-sectional survey of students in France. Read More

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Biomonitoring of occupational exposure to bisphenol A, bisphenol S and bisphenol F: A systematic review.

Sci Total Environ 2021 Apr 5;783:146905. Epub 2021 Apr 5.

French Research and Safety Institute for the Prevention of Occupational Accidents and Diseases (INRS), 1 rue du Morvan, 54519 Vandœuvre-Lès-Nancy, France.

Bisphenol A (BPA) and its substitutes bisphenol S (BPS) and bisphenol F (BPF) are endocrine disrupting chemicals widely used in the production of polycarbonate plastics, epoxy resins and thermal papers. The aim of the review was to identify occupational studies using human biomonitoring (HBM) as a tool for bisphenol exposure assessment and to characterize research gaps on the topic as part of the HBM4EU project. Hence, a systematic literature search using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology was conducted for articles published between 2000 and 27th March 2020 across three databases (PubMed, Scopus and Web of Science). Read More

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Detection of SARS-CoV-2 RNA in the Danube River in Serbia associated with the discharge of untreated wastewaters.

Sci Total Environ 2021 Apr 8;783:146967. Epub 2021 Apr 8.

University of Belgrade, Institute for Biological Research "Siniša Stanković", National Institute of Republic of Serbia, Department of Hydroecology and Water Protection, Bulevar despota Stefana 142, 11000 Belgrade, Serbia.

In Serbia less than 13% of collected municipal wastewaters is being treated before their release in the environment. This includes all municipal wastewater discharges from Belgrade (capital city of Serbia; population 1,700,000). Previous research has identified the impacts of raw wastewater discharges from Belgrade on the Danube River, and this study investigated if such discharges also provided a pathway for SARS-CoV-2 RNA material. Read More

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Application of crAssphage, F-RNA phage and pepper mild mottle virus as indicators of human faecal and norovirus contamination in shellfish.

Sci Total Environ 2021 Apr 1;783:146848. Epub 2021 Apr 1.

Institute of Environmental Science and Research Ltd (ESR), Porirua 5240, New Zealand. Electronic address:

Shellfish growing waters contaminated with inadequately treated human wastewater is a major source of norovirus in shellfish and poses a significant human health risk to consumers. Microbial source tracking (MST) markers have been widely used to identify the source (s) of faecal contamination in water but data are limited on their use for shellfish safety. This study evaluated the source specificity, sensitivity, occurrence and concentration of three viral MST markers i. Read More

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Modeling a gross motor curve of typically developing Dutch infants from 3.5 to 15.5 months based on the Alberta Infant Motor Scale.

Early Hum Dev 2021 Apr 1;157:105366. Epub 2021 Apr 1.

Faculty of Social and Behavioral Sciences, Department of Pedagogical and Educational Sciences, Utrecht University, Utrecht, the Netherlands.

Background: Interindividual variability in gross motor development of infants is substantial and challenges the interpretation of motor assessments. Longitudinal research can provide insight into variability in individual gross motor trajectories.

Purpose: To model a gross motor growth curve of healthy term-born infants from 3. Read More

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Occurrence, spatiotemporal distribution, seasonal and annual variation, and source apportionment of poly- and perfluoroalkyl substances (PFASs) in the northwest of Tai Lake Basin, China.

J Hazard Mater 2021 Apr 2;416:125784. Epub 2021 Apr 2.

School of Environment, Beijing Key Laboratory for Emerging Organic Contaminants Control, State Key Joint Laboratory of Environment Simulation and Pollution Control (SKLESPC), Tsinghua University, Beijing 100084, PR China; Research Institute for Environmental Innovation (Suzhou), Tsinghu, Building 16, 101 Business Park, No, 158 Jinfeng Road, New District, Suzhou 215163, PR China.

Poly- and perfluoroalkyl substances (PFASs) have attracted mounting attention due to their potential harmful effects and degradation-resistant property. This study continuously monitored the concentration of PFASs for four seasons in two years in the northwest of Tai Lake Basin. The occurrence, spatiotemporal distribution, seasonal and annual variation, and source apportionment of 13 PFASs were investigated in 60 surface water sampling sites and 33 emission sources. Read More

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The radical and non-radical oxidation mechanism of electrochemically activated persulfate process on different cathodes in divided and undivided cell.

J Hazard Mater 2021 Apr 6;416:125804. Epub 2021 Apr 6.

Key Laboratory of Pollution Process and Environmental Criteria, Ministry of Education, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China; Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution, Nankai University, Tianjin 300350, China; Tianjin Key Laboratory of Urban Ecology Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China; Tianjin Advanced Water Treatment Technology International Joint Research Center, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China.

Electrochemically activated persulfate (PS) employing stainless steel (SS), carbon felt (CF) and carbon black modified CF (CB-CF) as the cathode, in the divided and undivided cell, respectively, for degradation of atrazine (ATZ) was first investigated using novel B, Co-doped TiO nanotubes (B, Co-TNT) anode. In undivided cell, ATZ degradation was followed the order of CFRead More

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An induced pluripotent stem cell line (CSUi004-A) from skin fibroblasts of a healthy individual.

Stem Cell Res 2021 Apr 8;53:102336. Epub 2021 Apr 8.

Department of Geriatrics, Xiangya Hospital, Central South University, Changsha 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China; Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China; Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, Hunan 410008, China. Electronic address:

We established an induced pluripotent stem cell (iPSC) reprogrammed from dermal fibroblasts of a 53-year-old healthy man. Retroviruses expressing Yamanaka factors (OCT4, SOX2, KLF4 and c-MYC) were employed to initiate the reprogramming and were silenced in iPSCs. The generated iPSCs were pluripotent as determined by immunostaining and expression of pluripotency markers. Read More

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Spatial distributions and sources of PAHs in soil in chemical industry parks in the Yangtze River Delta, China.

Environ Pollut 2021 Apr 10;283:117121. Epub 2021 Apr 10.

Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; Hangzhou Institute for Advanced Study, UCAS, Hangzhou, 310024, China; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing, 100049, China. Electronic address:

The Yangtze River Delta (YRD) is one of the fastest developing areas in eastern China and contains many chemical industry parks. The profiles and sources of polycyclic aromatic hydrocarbons (PAHs) in soil in chemical industry parks and surrounding areas in the YRD were investigated by analyzing soil samples (n = 64) were collected in the YRD and Rudong chemical park (RD), a typical chemical park in the Yangtze River Delta. The total concentrations of 19 PAHs in the YRD soil samples were 16. Read More

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Implementing practices focused on workplace health and psychological wellbeing: A systematic review.

Soc Sci Med 2021 Apr 1;277:113888. Epub 2021 Apr 1.

Employment Systems and Institutions Group, Norwich Business School, University of East Anglia, NR4 7TJ, United Kingdom.

Rationale: Workplace health and wellbeing practices (WHWPs) often fail to improve psychological health or wellbeing because of implementation failure. Thus, implementation should be evaluated to improve the effectiveness of WHWPs.

Objective: We conducted a systematic review to identify critical success factors for WHWP implementation and gaps in the evidence. Read More

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Effects of substrate temperature on patterns produced by dried droplets of proteins.

Colloids Surf B Biointerfaces 2021 Apr 14;203:111763. Epub 2021 Apr 14.

Facultad de Ciencias en Física y Matemáticas, Universidad Autónoma de Chiapas, Tuxtla Gutiérrez, Chiapas, Mexico. Electronic address:

Rapid diagnosis provides better clinical management of patients, helps control possible outbreaks, and increases survival. The study of deposits produced by the evaporation of droplets is a useful tool in the diagnosis of some health problems. With the aim to improve diagnostic time in clinical practice where we use the evaporation of droplets, we explored the effects of substrate temperature on pattern formation of dried droplets in globular protein solutions. Read More

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Catalytically active peptides affected by self-assembly and residues order.

Colloids Surf B Biointerfaces 2021 Apr 7;203:111751. Epub 2021 Apr 7.

Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and Ilse Katz Institute for Nanoscience and Technology, Ben-Gurion University of the Negev POB 653, Beer-Sheva, 8410501, Israel. Electronic address:

Amphiphilic peptides that induce catalysis are interesting alternatives to natural enzymes thanks to robustness of their synthesis and the ability to induce certain types of conformations by specific motifs of amino acid sequences. Various studies aimed at mimicking the activity of serine proteases by designed peptides. Here we demonstrate that the order by which the catalytic triad residues are positioned along amphiphilic β-strands influences both assembly structures and catalytic activity. Read More

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Interscan measurement error of knee cartilage thickness and projected cartilage area ratio at 9 regions and 45 subregions by fully automatic three-dimensional MRI analysis.

Eur J Radiol 2021 Apr 8;139:109700. Epub 2021 Apr 8.

Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan. Electronic address:

Background: We have developed a fully automatic three-dimensional MRI analysis software program for automatic segmentation of knee cartilage using a deep neural network. The purpose of this study was to use this software to clarify the interscan measurement error of the knee cartilage thickness and projected cartilage area ratio at 9 regions and 45 subregions in the knee.

Methods: Ten healthy volunteers underwent MRI twice in the same day. Read More

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