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Predictive model for growth of Clostridium perfringens during cooling of cooked pork supplemented with sodium chloride and sodium pyrophosphate.

Meat Sci 2021 Oct 14;180:108557. Epub 2021 May 14.

Department of Food Science & Technology, University of Georgia, Athens, GA 30602, United States of America.

A dynamic model was developed to predict growth of Clostridium perfringens in cooked ground pork supplemented with salt (0-3% wt/wt) and sodium pyrophosphate (0-0.3% wt/wt) under varying temperatures. C. Read More

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October 2021

Adaptation and Validation of the Dynamic Imaging Grade of Swallowing Toxicity for Flexible Endoscopic Evaluation of Swallowing: DIGEST-FEES.

J Speech Lang Hear Res 2021 Jun 25;64(6):1802-1810. Epub 2021 May 25.

University of Texas MD Anderson Cancer Center, Houston, TX.

Purpose While flexible endoscopic evaluation of swallowing (FEES) is a common clinical procedure used in the head and neck cancer (HNC) population, extant outcome measures for FEES such as bolus-level penetration-aspiration and residue scores are not well suited as global patient-level endpoint measures of dysphagia severity in cooperative group trials or clinical outcomes research. The Dynamic Imaging Grade of Swallowing Toxicity (DIGEST) was initially developed and validated for use during videofluoroscopic evaluations as a way to grade safety, efficiency, and overall pharyngeal swallowing impairment. The purpose of this study was to adapt and validate DIGEST for use with FEES. Read More

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Use of lemongrass essential oil as a feed additive in quail's nutrition: its effect on growth, carcass, blood biochemistry, antioxidant and immunological indices, digestive enzymes and intestinal microbiota.

Poult Sci 2021 Jun 26;100(6):101172. Epub 2021 Mar 26.

Poultry Department, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.

The present study was designed to assess the impact of dietary supplementation of lemongrass essential oil (LGEO) on growth performance, carcass traits, liver and kidney function, immunity, antioxidant indices and caecal microbiota of growing quail. A total of 200 Japanese quails at 1-week-old were haphazardly allotted to 5 groups of 40 chicks in five replicates (8 per replicate). The first group was the control group, while LGEO was added at levels of 150, 300, 450, and 600 mg/kg diet in the 2nd, 3rd, 4th and 5th groups, respectively. Read More

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In vitro efficacy of plant extracts against gastrointestinal nematodes in goats.

Trop Anim Health Prod 2021 Apr 29;53(2):295. Epub 2021 Apr 29.

Animal and Poultry Science, School of Agricultural, Earth and Environmental Sciences, University of KwaZulu-Natal, P Bag X01 Scottsville, Pietermaritzburg, 3209, South Africa.

Farmers use plant extracts as a potential source of anthelmintic compounds against gastrointestinal nematodes in goats. The objective of the study was to investigate the in vitro anthelmintic activity of aqueous (cold and boiled) and methanolic extracts of Cissus quadrangularis Linn., Aloe marlothii A. Read More

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Age and time trends of dairy intake among children and adolescents of the DONALD study.

Eur J Nutr 2021 Apr 21. Epub 2021 Apr 21.

Department of Nutritional and Food Sciences, Nutritional Epidemiology, University of Bonn, DONALD Study Dortmund, Heinstück 11, 44225, Dortmund, Germany.

Purpose: To describe age and time trends in dietary intake of Total Dairy (TD) (g/1000 kcal Total Energy Intake) and types of dairy (weight percent of total dairy intake, w%TD) represented as Low Fat Dairy (LFD), High Sugar Dairy (HSD), Fermented Dairy (FD) and Liquid Dairy (LD) among children and adolescents in Germany.

Methods: Overall, 10,333 3-day dietary records kept between 1985 and 2019 by 1275 DONALD participants (3.5-18. Read More

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Trends in substances involved in polysubstance overdose fatalities in Maryland, USA 2003-2019.

Drug Alcohol Depend 2021 Jun 12;223:108700. Epub 2021 Apr 12.

Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD, 21205, USA.

Background: The substances driving the overdose epidemic in the United States have changed over time. Since 2013, fentanyl-analogues have become the primary opioids driving the epidemic. Recently, polysubstance related deaths have come to the forefront of the epidemic. Read More

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Has the excess risk of acute myocardial infarction in rheumatoid arthritis relative to the general population declined? A population study of trends over time.

Semin Arthritis Rheum 2021 04 2;51(2):442-449. Epub 2021 Mar 2.

Arthritis Research Canada, 5591 Number 3 Rd, Richmond V6X 2C7, British Columbia, Canada; Division of Rheumatology, Department of Medicine, Faculty of Medicine, University of British Columbia, Canada; Experimental Medicine, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada. Electronic address:

Objective: To evaluate secular trend in ten-year risk of incident acute myocardial infarction (AMI) in incident rheumatoid arthritis (RA) relative to the general population.

Methods: We conducted a retrospective study of population-based incident RA cohorts with RA incidence from 1997 to 2004 in British Columbia, Canada, with matched general population comparators, using administrative health data. RA and their matched cohorts were divided according to the year of RA incidence, defined according to the first RA visit of the case definition. Read More

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Growth performance and fertility of Windsnyer boars supplemented with α-tocopherol.

Trop Anim Health Prod 2021 Feb 12;53(1):161. Epub 2021 Feb 12.

Department of Agricultural, Earth and Environmental Science, Animal and Poultry Science, University of KwaZulu-Natal, Private Bag X01, Scottsville, Pietermaritzburg, 3209, South Africa.

The purpose of the present work was to determine the response in growth performance and spermatozoa characteristics of Windsnyer boars supplemented with progressive levels of α-tocopherol. Twenty Windsnyer boars aged 12 weeks with an average body weight of 19.5 ± 2. Read More

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February 2021

Optimisation of Epoxide Ring-Opening Reaction for the Synthesis of Bio-Polyol from Palm Oil Derivative Using Response Surface Methodology.

Molecules 2021 Jan 27;26(3). Epub 2021 Jan 27.

Department of Chemical and Environmental Engineering, Faculty of Engineering, University Putra Malaysia, Serdang 43400, Selangor, Malaysia.

The development of bio-polyol from vegetable oil and its derivatives is gaining much interest from polyurethane industries and academia. In view of this, the availability of methyl oleate derived from palm oil, which is aimed at biodiesel production, provides an excellent feedstock to produce bio-polyol for polyurethane applications. In this recent study, response surface methodology (RSM) with a combination of central composite rotatable design (CCRD) was used to optimise the reaction parameters in order to obtain a maximised hydroxyl value (OHV). Read More

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January 2021

Modelling normal age-related changes in individual retinal layers using location-specific OCT analysis.

Sci Rep 2021 Jan 12;11(1):558. Epub 2021 Jan 12.

Centre for Eye Health, University of New South Wales, Sydney, 2052, Australia.

Current descriptions of retinal thickness across normal age cohorts are mostly limited to global analyses, thus overlooking spatial variation across the retina and limiting spatial analyses of retinal and optic nerve disease. This retrospective cross-sectional study uses location-specific cluster analysis of 8 × 8 macular average grid-wise thicknesses to quantify topographical patterns and rates of normal, age-related changes in all individual retinal layers of 253 eyes of 253 participants across various age cohorts (n = 23-69 eyes per decade). Most retinal layers had concentric spatial cluster patterns except the retinal nerve fibre layer (RNFL) which displayed a nasal, asymmetric radial pattern. Read More

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January 2021

Establishing a Reference Dose-Response Calibration Curve for Dicentric Chromosome Aberrations to Assess Accidental Radiation Exposure in Saudi Arabia.

Front Public Health 2020 15;8:599194. Epub 2020 Dec 15.

Radiation Biology Section, Biomedical Physics Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

In cases of nuclear and radiological accidents, public health and emergency response need to assess the magnitude of radiation exposure regardless of whether they arise from disaster, negligence, or deliberate act. Here we report the establishment of a national reference dose-response calibration curve (DRCC) for dicentric chromosome (DC), prerequisite to assess radiation doses received in accidental exposures. Peripheral blood samples were collected from 10 volunteers (aged 20-40 years, median = 29 years) of both sexes (three females and seven males). Read More

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Efficient derivation of significant results from mechanical processing experiments with mixed solid waste: Coarse-shredding of commercial waste.

Waste Manag 2021 Feb 25;121:164-174. Epub 2020 Dec 25.

Department of Environmental and Energy Process Engineering, Chair of Waste Processing Technology and Waste Management, Montanuniversitaet Leoben - Franz-Josef-Straße 18, 8700 Leoben, Austria. Electronic address:

Deriving significant experiment-based conclusions on mechanical processing of mixed solid waste is challenging: the input material cannot be downscaled in a way that enables drawing transferable conclusions from lab-scale experiments. Hence experiments need to be conducted in industry-scale, using real waste. Besides the enormous resulting experimental efforts and costs, which economically limit the number of experimental runs, identifying and quantifying significant effects is complicated by the distortion of the data introduced by the waste's variability. Read More

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February 2021

Evaluating the relationship between fecal egg count, FAMACHA score, and weight in dewormed and non-dewormed Katahdin rams during a parasite challenge.

Transl Anim Sci 2020 Oct 24;4(4):txaa178. Epub 2020 Sep 24.

Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA.

The objective of this study was to evaluate and to estimate the relationship between fecal egg counts (FECs) and FAMACHA score and the body weight of growing Katahdin rams during a parasite challenge. One of the largest factors negatively influencing reproduction and economics in the sheep industry is gastrointestinal nematode (GIN) parasites. Due to anthelmintic resistance of these parasites, animals are selected for parasite resistance using FEC and FAMACHA scores. Read More

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October 2020

Gastric emptying in healthy children using the Spirulina breath test: The impact of gender, body size, and pubertal development.

Neurogastroenterol Motil 2021 Jun 10;33(6):e14063. Epub 2020 Dec 10.

Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: There are no pediatric norms for gastric emptying (GE) measured by nuclear scintigraphy. The C-labeled, stable isotope GE breath test (GEBT) is a non-radioactive alternative. We aimed to determine normative GEBT ranges in a cohort of healthy children and examine the influence of age, gender, puberty, and body surface area (BSA). Read More

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Ten-year risk of cerebrovascular accidents in incident rheumatoid arthritis: a population-based study of trends over time.

Rheumatology (Oxford) 2021 May;60(5):2267-2276

Arthritis Research Canada, Richmond.

Objective: To evaluate secular trends in 10-year risk of incident cerebrovascular accidents (CVA), in incident RA relative to the general population.

Methods: We conducted a retrospective study of a population-based incident cohort with RA onset from 1997 to 2004 in British Columbia, Canada, with matched general population controls (2:1), using administrative health data. RA and general population cohorts were divided according to year of RA onset, defined according to the first RA visit of the case definition. Read More

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The Development of a Regression Model to Predict Object Transfer Power in Older Adults.

J Strength Cond Res 2020 Nov;34(11):3086-3093

Department of Kinesiology and Sports Sciences, University of Miami, Max Orovitz Laboratory of Neuromuscular Research and Active Aging, Coral Gables, Florida.

Castillo, DC, Strand, KL, Oh, J, Eltoukhy, M, Totillo, MC, and Signorile, JF. The development of a regression model to predict object transfer power in older adults. J Strength Cond Res 34(11): 3086-3093, 2020-Declines in mechanical power affect independence in older adults; however, no practical clinical method exists to assess peak power (PP) and average power (AP) during transfer tasks in this population. Read More

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November 2020

Test the Effectiveness of Quantitative Linear-Quadratic-Based (qLQB) Model on Evaluating Irradiation-Induced Liver Injury (ILI) Against Normal Tissue Complication Probability (NTCP).

Dose Response 2020 Jul-Sep;18(3):1559325820961721. Epub 2020 Sep 22.

Department of Radiation Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Kunming, Yunnan, China.

Objectives: To test the effectiveness of quantitative linear-quadratic-based (qLQB) model on evaluating irradiation-induced liver injury (ILI) and establish the relation between the damaged ratio/percent (DRP) in qLQB model and normal tissue complication probility (NTCP).

Materials And Methods: We established the qLQB model to calculate the ratio/percent (RP) between damaged cell/functional subunit (FSU) and entire cell/FSU of liver for radiation dose response, tested the qLQB against the Lyman-Kutcher-Burman (LKB) model, and established relation between the RP and NTCP through analyzing the dose of 32 patients with cancer of abdominal cavity who were treated with radiation therapy at our department. Based on varied α/β and varied parameters for NTCP, we put the calculated results into varied arrays for the next analysis. Read More

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September 2020

An Approach Towards Optimization Appraisal of Thermal Conductivity of Magnetic Thermoplastic Elastomeric Nanocomposites Using Response Surface Methodology.

Polymers (Basel) 2020 Sep 6;12(9). Epub 2020 Sep 6.

Department of Physics, College of Science, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.

This study investigates the optimization of thermal conductivity of nickel zinc ferrite incorporated thermoplastic natural rubber nanocomposites using response surface methodology (RSM). The experimental runs were based on face-centered central composite design (FCCD) where three levels were designated for both temperature and magnetic filler content. The analysis of variance (ANOVA) results showed that the implemented technique is significant with an F-value of 35. Read More

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September 2020

2-Nitro-1-propanol improved nutrient digestibility and oocyst shedding but not growth performance of Eimeria-challenged broilers.

Poult Sci 2020 Sep 25;99(9):4314-4322. Epub 2020 Jun 25.

Department of Poultry Science, University of Georgia, Athens, GA, USA. Electronic address:

A 2 × 3 factorial arrangement study was conducted to evaluate 3 dosages of 2-nitro-1-propanol (NP; 0, 150, and 200 ppm) on intestinal health of birds with or without Eimeria challenge. A total of 432 thirteen-day-old male broiler chickens were randomly allocated to 6 treatments with 8 replicate cages of 9 birds per cage. All birds were fed with treatment diets from day 13 to 21. Read More

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September 2020

Pathways regulating equine skeletal muscle protein synthesis respond in a dose-dependent manner to graded levels of protein intake.

J Anim Sci 2020 Sep;98(9)

Department of Animal and Food Sciences, University of Kentucky, Lexington, KY.

Activation of the mechanistic target of rapamycin (mTOR)-controlled anabolic signaling pathways in skeletal muscle of rodents and humans is responsive to the level of dietary protein supply, with maximal activation and rates of protein synthesis achieved with 0.2 to 0.4 g protein/kg body weight (BW). Read More

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September 2020

Genotype-phenotype correlation in 667 Chinese families with spinocerebellar ataxia type 3.

Parkinsonism Relat Disord 2020 09 4;78:116-121. Epub 2020 Aug 4.

Department of Neurology and Research Center of Neurology in Second Affiliated Hospital, And Key Laboratory of Medical Neurobiology of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:

Introduction: Due to diverse symptoms of spinocerebellar ataxia type 3 (SCA3) and the high prevalence of SCA3 in China, a more in-depth study of Chinese SCA3 patients in a large cohort is well merited.

Methods: During the last 10 years, 730 patients and 133 premanifest individuals from 667 SCA3 families genetically confirmed to have SCA3 were enrolled from three leading academic hospitals in China. The clinical profile and genotype-phenotype correlation were analyzed. Read More

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September 2020

Effect of tidal volume and end tracheal tube leakage on end-tidal CO in very low birth weight infants.

J Perinatol 2021 01 4;41(1):47-52. Epub 2020 Aug 4.

Division of Pediatrics, Fukuda Hospital, Kumamoto, Japan.

Objective: To examine the extents to which low tidal volume (VT) and endotracheal tube (ETT) leakeage influence the accuracy of ETCO for estimating arterial PCO (PaCO) in very low birth weight (VLBW) infants with mechanical ventilation.

Study Design: An observational study. We evaluated a total of 287 paired ETCO and PaCO values as well as VTs obtained from 22 VLBW infants with ventilation. Read More

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January 2021

Application of diatomite for sorption of Pb, Cu, Cd and Zn from aqueous solutions: kinetic, thermodynamic studies and application of response surface methodology (RSM).

Water Environ Res 2021 May 27;93(5):714-726. Epub 2020 Dec 27.

Department of Food Science and Technology, Faculty of Agriculture, Urmia University, Urmia, Iran.

Contamination of water and soil with toxic metals is a serious environmental issue. To study the Pb, Cu, Cd, and Zn sorption behavior by diatomite, batch experiments were carried out with increasing levels of initial concentration (0-200 mg/L) under different contact times (0-360 min) and temperatures (283, 293, 303, and 313 K). The effects of concentration (0-200 mg/L), pH (3-6), and ionic strength (0. Read More

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Adsorption onto MWCNTs Coupled with Cloud Point Extraction for Dye Removal from Aqueous Solutions: Optimization by Experimental Design.

Comb Chem High Throughput Screen 2021 ;24(2):246-258

Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran.

Aims: The main aim of the study was to examine the feasibility and benefits of adsorption onto multi-walled carbon nanotubes (MWCNTs) coupled with cloud point extraction (CPE) for the removal of Rhodamine B (RB) from aqueous solutions.

Background: MWCNTs offer the particular features of the ideal adsorbents for the organic dyes such as hollow tubular structure and specific surface area. Nevertheless, they suffer from the drawbacks of low dispersion in the aqueous solutions and separation inconvenience from the media. Read More

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January 2021

An Improved Nanoemulsion Formulation Containing Kojic Monooleate: Optimization, Characterization and In Vitro Studies.

Molecules 2020 Jun 4;25(11). Epub 2020 Jun 4.

Department of Bioprocess Technology, Faculty of Biotechnology, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.

Tyrosinase inhibitors have become increasingly important targets for hyperpigmentation disease treatment. Kojic monooleate (KMO), synthesized from the esterification of kojic acid and oleic acid, has shown a better depigmenting effect than kojic acid. In this study, the process parameters include the speed of high shear, the time of high shear and the speed of the stirrer in the production of nanoemulsion containing KMO was optimized using Response Surface Methodology (RSM), as well as evaluated in terms of its physicochemical properties, safety and efficacy. Read More

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A low-cost solvent-free method to synthesize α-FeO nanoparticles with applications to degrade methyl orange in photo-fenton system.

Ecotoxicol Environ Saf 2020 Sep 24;200:110744. Epub 2020 May 24.

School of Chemical Engineering of Sichuan University, Chengdu, 610065, PR China; Engineering Research Center of Comprehensive Utilization and Clean Processing of Phosphorus Resources, Ministry of Education, Chengdu, 610065, PR China.

Hematite nanoparticles (α-FeO NPs) were successfully synthesized by a low-cost solvent-free reaction using Ferrous sulfate waste (FeSO·7HO) and pyrite (FeS) as raw materials and employed for the decolorization of Methyl Orange by the photo-Fenton system. The properties of α-FeO NPs before and after photo-Fenton reaction were characterized by X-ray powder diffraction (XRD), Field emission scanning electron microscopy (FESEM), Fourier transform infrared (FT-IR) spectrum and X-ray photoelectron spectroscopy (XPS), and the optical properties of α-FeO NPs were analyzed by UV-vis diffuse reflectance spectra (UV-vis DRS) and Photoluminescence (PL) spectra. The analytic results showed that the as-formed samples having an average diameter of ~50 nm exhibit pure phase hematite with sphere structure. Read More

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September 2020

Cervical cancer incidence and mortality rates in Kentucky.

Gynecol Oncol 2020 08 23;158(2):446-451. Epub 2020 May 23.

Department of Radiation Oncology, James Graham Brown Cancer Center, University of Louisville School of Medicine, 529 S. Jackson St., Louisville, KY 40202, United States of America.

Objectives: The goal of this study was to assess how the incidence and mortality of cervical cancer in Kentucky has changed from 1995 through 2017. Additionally, trends in incidence and mortality across different geographic areas and between different races were evaluated.

Methods: Age-adjusted annual incidence and mortality rates for cervical cancer were collected from the Kentucky Cancer Registry (KCR). Read More

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Removing methylene blue contained in dye wastewater using a novel liquid-phase plasma discharge process.

J Environ Sci Health A Tox Hazard Subst Environ Eng 2020 20;55(8):1032-1039. Epub 2020 May 20.

Environmental Science Program, University of Idaho, Moscow, ID USA.

In this study, a newly developed liquid-phase plasma discharge (LPPD) process was evaluated for removing methylene blue (MB) in water. Three independent variables, i.e. Read More

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Predicting Knee Joint Instability Using a Tibio-Femoral Statistical Shape Model.

Front Bioeng Biotechnol 2020 17;8:253. Epub 2020 Apr 17.

Orthopaedic and Trauma Department, "Luigi Sacco" Hospital, ASST FBF-Sacco, Milan, Italy.

Statistical shape models (SSMs) are a well established computational technique to represent the morphological variability spread in a set of matching surfaces by means of compact descriptive quantities, traditionally called "modes of variation" (MoVs). SSMs of bony surfaces have been proposed in biomechanics and orthopedic clinics to investigate the relation between bone shape and joint biomechanics. In this work, an SSM of the tibio-femoral joint has been developed to elucidate the relation between MoVs and bone angular deformities causing knee instability. Read More

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