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Clustering of trisomy 18 in Kuwait: Genetic predisposition or environmental?

Ann Saudi Med 1999 May-Jun;19(3):197-200

Kuwait Medical Genetic Centre, and Department of Community Medicine, Kuwait University, Kuwait.

Background: This study describes 59 newborns with regular trisomy 18 (EdwardsA centAA syndrome, T18) who were ascertained clinically and cytogenetically at the Kuwait Medical Genetic Centre from 1994 to 1997, out of 118 T18 cases identified from 1980 to 1997.

Materials And Methods: T18 cases were ascertained clinically and cytogenetically shortly after birth. In addition to assessing the T18 birth prevalence rate and confidence limits during the years 1994-1997, we investigated the possible etiological factors by a case-control study with normal healthy newborns. Read More

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October 2012
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