7 results match your criteria σ-factor genes

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Computational Method for Identifying Malonylation Sites by Using Random Forest Algorithm.

Comb Chem High Throughput Screen 2020 ;23(4):304-312

School of Life Sciences, Shanghai University, Shanghai 200444, China.

Background: As a newly uncovered post-translational modification on the ε-amino group of lysine residue, protein malonylation was found to be involved in metabolic pathways and certain diseases. Apart from experimental approaches, several computational methods based on machine learning algorithms were recently proposed to predict malonylation sites. However, previous methods failed to address imbalanced data sizes between positive and negative samples. Read More

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Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood.

J Gerontol A Biol Sci Med Sci 2019 02;74(3):283-289

Division of Geriatrics, Duke University School of Medicine, Durham, North Carolina.

Aging is characterized by deleterious immune and metabolic changes, but the onset of these changes is unknown. We measured immune and metabolic biomarkers in adults beginning at age 30. To our knowledge, this is the first study to evaluate these biomarkers in adults aged 30 to over 80. Read More

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February 2019

Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations.

J Gerontol A Biol Sci Med Sci 2016 11 16;71(11):1507-1513. Epub 2016 Mar 16.

Claude D. Pepper Older Americans Independence Center/Center for the Study of Aging and Human Development.

Background: Older age and obesity are associated with metabolic dysregulation; the mechanism by which these factors impact metabolism across the lifespan is important, but relatively unknown. We evaluated a panel of amino acids (AAs) and acylcarnitines (ACs) to identify effects of age and adiposity (body mass index) on circulating small-molecule metabolites in a meta-analysis of six diverse study populations.

Methods: Targeted metabolic profiling was performed in six independent studies, representing 739 subjects with a broad range of age, body mass index, health states, and ethnic origin. Read More

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November 2016

Validation of a motivation-based typology of angry aggression among antisocial youths in Norway.

Behav Sci Law 2012 Mar-Apr;30(2):167-80. Epub 2012 Mar 4.

Norwegian Center for Child Behavioral Development, Oslo, Norway.

This article describes the validation of the Angry Aggression Scales (AAS), the Behavior Inhibition System and the Behavior Activation System (BIS/BAS) scales, the reactive aggression and proactive power scales in relation to a Norwegian sample of 101 antisocial youths with conduct problems (64 boys, 37 girls, mean age 15 ± 1.3 years) and 101 prosocial controls matched on age, gender, education, ethnicity, and school district. Maximum likelihood exploratory factor analyses with oblique rotation were performed on AAS, BIS/BAS, reactive aggression and proactive power scales as well as computation of Cronbach's alpha and McDonald's omega. Read More

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September 2012

[Identification of the autoagglutination factor of Hms- cells of the plague agent].

Mol Gen Mikrobiol Virusol 2006 (2):25-9

A search for cellular components responsible for autoagglutination (AA) in broth and salt solutions of Hms- cells of the plague agent Yersinia pestis was performed. The AA- mutants were obtained using vaccine strain Y. pestis EV76 derivative containing one species-specific plasmid pYP. Read More

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The amino acid factor in stone formers' and normal urines.

Urol Res 1986 ;14(6):295-8

The composition of amino-acids in kidney stone matrices and inhibitory materials from normal urines, reported in different independent studies has been reviewed. No obvious difference was found between the composition of amino acids from healthy and pathological sources. Studies carried out in this laboratory showed a specific marked effect of glutamic acid on the crystallization of calcium oxalate while aspartic acid and alanine affected the process very slightly. Read More

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HBsAg glomerular deposits in glomerulonephritis: fact or artifact?

Kidney Int 1981 Apr;19(4):579-86

To evaluate the role of the hepatitis B virus infection in the pathogenesis of glomerulonephritis, we screened 136 consecutive patients with various types of glomerular lesions for the presence of HBsAg either in serum or in kidney biopsy specimens by means of radioimmunoassay and direct immunofluorescence technique, respectively. In selected patients, we carried out the search for antiglobulin activity (AA) factor(s) within the renal tissue with a fluoresceinated aggregated human IgG preparation (FITC-IgGagg). Eleven HbsAg seropositive patients were found, none of whom showed HBsAg deposits within their kidney biopsy specimen. Read More

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