Curr Opin Crit Care 2021 Sep 15. Epub 2021 Sep 15.
Department of Critical Care, King's College London, Guy's & St Thomas' NHS Foundation Trust, London, UK Department of Internal Medicine, National Taiwan University Hospital The National Taiwan University Study Group on Acute Renal Failure, Taipei, Taiwan Department of Anesthesiology and Intensive Care Medicine, Pavlov First Saint-Petersburg State Medical University, Saint Petersburg, Russia Division of Nephrology, Department of Internal Medicine and Excellence Center in Critical Care Nephrology, King Chulalongkorn Memorial Hospital Research Unit in Critical Care Nephrology, Chulalongkorn University, Bangkok, Thailand.
Purpose Of Review: The current definition and classification of acute kidney injury (AKI) has limitations and shortcomings, which impact clinical management. The aim of this review is to highlight recent advances in our understanding of the pathophysiology and epidemiology of AKI, which impacts management and offers opportunities.
Recent Findings: Kidney damage varies according to the type of primary insult, secondary effects and mitigating responses and leads to distinct molecular, cellular and functional changes. Read More