14,761 results match your criteria [photodermatitis

A Woman With Solar Urticaria and Heat Urticaria: A Unique Presentation of an Individual With Multiple Physical Urticarias.

Cureus 2021 Aug 6;13(8):e16950. Epub 2021 Aug 6.

Dermatology, San Diego Family Dermatology, National City, USA.

Urticaria is a common group of dermatologic disorders characterized by hives. Solar urticaria and heat urticaria are two rare types of chronic inducible urticarias. Solar urticaria is triggered by exposure to sunlight or ultraviolet radiation. Read More

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Sun-health behaviours and attitudes towards sun safety amongst Australian teenagers: a qualitative update.

BMC Res Notes 2021 Sep 8;14(1):349. Epub 2021 Sep 8.

Telethon Kids Institute, University of Western Australia, 15 Hospital Ave, Nedlands, WA, 6008, Australia.

Objective: This study aimed to explore current attitudes towards sun protection, and sun-seeking behaviour among young Australian adolescents. It was done as part of a larger project aiming to develop a digital resource to support young people in making informed sun-health decisions.

Results: Ten (4 male, 6 female) adolescents (12-13 years of age) living in Perth (Western Australia) were recruited through a social media-based strategy. Read More

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September 2021

Comments on the mechanisms of retinal phototoxicity.

Arch Soc Esp Oftalmol (Engl Ed) 2021 09 12;96(9):505. Epub 2021 Jun 12.

Servicio de Oftalmología, Hospital Universitario del Henares, Madrid, Spain.

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September 2021

Maculopapular Cutaneous Mastocytosis Successfully Treated with Omalizumab.

Acta Dermatovenerol Croat 2021 Apr;291(1):60-61

Theodora Kanni, MD, PhD, Department of Dermatology and Venereology Andreas Sygros Hospital , 5 Ionos Dragoumi Str, 161 21 Athens, Greece;

Dear Editor, Maculopapular cutaneous mastocytosis (MPCM), formerly telangiectasia macularis eruptiva perstans (TMEP), is an uncommon form of cutaneous mastocytosis first described on 1930 (1). It is more frequent in adults, and early diagnosis is crucial since it has been reported to be associated with serious underlying systemic disorders, such as myeloproliferative diseases and severe manifestations like anaphylaxis (2,3). Treatment of MPCM depends on the presence of systemic involvement and/or the clinical symptoms of the disease itself. Read More

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Photodiagnostic services in the UK and Republic of Ireland: a British Photodermatology Group Workshop Report.

J Eur Acad Dermatol Venereol 2021 Aug 30. Epub 2021 Aug 30.

Department of Dermatology, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK.

Background: Photodiagnostic investigations are essential for the accurate diagnosis of abnormal cutaneous photosensitivity and provide important information for the management of patients with photodermatoses (cutaneous photosensitivity disorders). Although photodiagnosis has been undertaken since the early 1970s, specialist services in the United Kingdom (UK) and Republic of Ireland are limited and there is no formal guidance on diagnostic approach. Indeed, there is a limited literature in this area of methodology and diagnostic practice. Read More

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Xeroderma pigmentosum and acute myeloid leukemia: a case report.

J Med Case Rep 2021 Aug 26;15(1):437. Epub 2021 Aug 26.

Hematology and Oncology Pediatric Department, Hospital August 20, 1953, 6 Rue Lahcen Al Arjoun, Casablanca, Morocco.

Background: Xeroderma pigmentosum is a rare inherited disease characterized by extreme hypersensitivity to ultraviolet rays and predisposing to cutaneous malignancies that can appear in childhood. These manifestations are often associated with ocular lesions and sometimes with neurological disorders. The association of xeroderma pigmentosum with internal neoplasms such as acute myeloblastic leukemia is not reported with great frequency, which confirms the rarity of this occurrence. Read More

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Isoconazole and Clemizole Hydrochloride Partially Reverse the Xeroderma Pigmentosum C Phenotype.

Int J Mol Sci 2021 Jul 29;22(15). Epub 2021 Jul 29.

Biomics, IRIG-BGE U1038, INSERM, Univ. Grenoble Alpes, 38000 Grenoble, France.

Xeroderma Pigmentosum protein C (XPC) is involved in recognition and repair of bulky DNA damage such as lesions induced by Ultra Violet (UV) radiation. -mutated cells are, therefore, photosensitive and accumulate UVB-induced pyrimidine dimers leading to increased cancer incidence. Here, we performed a high-throughput screen to identify chemicals capable of normalizing the XP-C phenotype (hyper-photosensitivity and accumulation of photoproducts). Read More

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Prevention of racialized medicine in pediatric dermatology: A call to re-examine skin tone typing.

Pediatr Dermatol 2021 Aug 6. Epub 2021 Aug 6.

Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA.

The Fitzpatrick skin phototype (FSPT), a biologic concept originally constructed in light-skinned patients to measure UVA sensitivity, is widely used today across pediatric dermatology as a proxy for race, a social and political construct. We outline why this is problematic and could contribute to racially inequitable care and discuss the broader question of whether skin tone is relevant to measure in all cases. We propose that, instead of indiscriminately measuring skin tone in all clinical cases, pediatric dermatologists choose the skin characterization variable most relevant to their patient's condition. Read More

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Hereditary Chorea Associated With and Aggravated by Systemic Lupus Erythematosus.

Cureus 2021 Jun 28;13(6):e15992. Epub 2021 Jun 28.

Internal Medicine, Sandeman Provincial Hospital, Quetta, PAK.

Chorea is caused by a number of conditions, including genetic, metabolic derangements, infections, drugs, toxins, tumors, and disorders of the immune and inflammatory system of the body. Huntington's disease (HD) is the most common genetic cause of chorea. Systemic lupus erythematosus (SLE) is an autoimmune condition. Read More

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Sunburn, Sun Safety and Indoor Tanning Among Schoolchildren in Ireland.

Int J Public Health 2021 20;66:1604045. Epub 2021 May 20.

Health Promotion Research Centre, National University of Ireland Galway, Galway, Ireland.

We present patterns of sunburn, sun safety behaviors and indoor tanning bed use in a nationally representative sample of schoolchildren aged 10-17. These behaviors were explored across gender, age, and social class groups. Within the Health Behaviour in School-aged Children (HBSC) Ireland study, 10,271 young people (aged 13. Read More

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Clinical and biochemical footprints of inherited metabolic diseases. VI. Metabolic dermatoses.

Mol Genet Metab 2021 Jul 21. Epub 2021 Jul 21.

Division of Metabolism, University Children's Hospital, Zürich, Switzerland. Electronic address:

Cutaneous signs and symptoms may facilitate the diagnosis or can help in identifying complications or side effects of overtreatment of inherited metabolic diseases. The principal manifestations can be grouped into vascular lesions, ichthyosis, papular and nodular skin lesions, abnormal pigmentation, photosensitivity, skin laxity, hair shaft involvement, and nail abnormalities. We have summarized associations of these cutaneous signs and symptoms in 252 inherited metabolic diseases. Read More

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Golfers' Interest in Multilevel Sun-Protection Strategies.

Int J Environ Res Public Health 2021 07 7;18(14). Epub 2021 Jul 7.

Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802, USA.

Active adults accumulate more ultraviolet (UV) radiation exposure and are at greater risk of skin cancer than inactive adults. Golf is a popular sport that increases UV exposure because it is played outdoors in daylight. This study evaluated adult golfers' interest in multilevel sun-protection strategies and characterized differences in interest as a function of golfer characteristics. Read More

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Photodistributed toxic epidermal necrolysis in association with lamotrigine and tanning bed exposure.

JAAD Case Rep 2021 Aug 2;14:68-71. Epub 2021 Jun 2.

Department of Dermatology, Medstar Washington Hospital Center/Georgetown University Hospital, Washington, DC.

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Seven- and 23-year-old Siblings with Papulonodular Lesions after Sun Exposure: A Quiz.

Acta Derm Venereol 2021 Jul 30;101(7):adv00513. Epub 2021 Jul 30.

Department of Dermatology, Venereology and Allergology, Charité Universitätsmedizin, Berlin, Germany.

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No pain, no gain: Sensory neurons heal a sunburn.

Immunity 2021 07;54(7):1374-1376

Center for Immunology & Inflammatory Diseases, Division of Rheumatology, Allergy, & Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

In a recent issue of Nature, Hoeffel et al. describe a novel pathway of sterile tissue repair utilizing a mouse model of sunburn. This wound healing pathway is coordinated by sensory neuron-derived TAFA4 that induces IL-10 production from Tim4 dermal macrophages to prevent sustained inflammation and the emergence of tissue fibrosis. Read More

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Nucleotide Excision Repair: From Molecular Defects to Neurological Abnormalities.

Int J Mol Sci 2021 Jun 9;22(12). Epub 2021 Jun 9.

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.

Nucleotide excision repair (NER) is the most versatile DNA repair pathway, which can remove diverse bulky DNA lesions destabilizing a DNA duplex. NER defects cause several autosomal recessive genetic disorders. Xeroderma pigmentosum (XP) is one of the NER-associated syndromes characterized by low efficiency of the removal of bulky DNA adducts generated by ultraviolet radiation. Read More

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A Case of Concurrent Molybdenosis, Secondary Copper, Cobalt and Selenium Deficiency in a Small Sheep Herd in Northern Germany.

Animals (Basel) 2021 Jun 23;11(7). Epub 2021 Jun 23.

Clinic for Swine and Small Ruminants, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, 30173 Hannover, Germany.

To the author's knowledge this paper describes the first proven report of a combined primary molybdenosis, secondary copper (Cu) deficiency, Ovine White Liver Disease-Cobalt (Co) deficiency, and selenium (Se) deficiency in a small pedigree herd of White Horned Heath sheep in Germany (8 ewes, 2 rams, 3 yearling ewes, 17 lambs) for decades. Clinical signs associated with these mineral deficiencies in a group of pastured ram lambs included emaciation, conjunctivitis, anaemia, growth retardation, discolouration of the wool and photodermatitis. Morbidities and mortalities arose in 4-6-month-old lambs despite intensive veterinary treatment in the summer of 2014 and 2015 ( = 13, 23% died). Read More

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Bioinformatics and expression analysis of the Xeroderma Pigmentosum complementation group C (XPC) of Trypanosoma evansi in Trypanosoma cruzi cells.

Braz J Biol 2021 28;83:e243910. Epub 2021 Jun 28.

Universidade do Estado de Santa Catarina, Departamento de Produção Animal e Alimentos, Lages, SC, Brasil.

Nucleotide excision repair (NER) acts repairing damages in DNA, such as lesions caused by cisplatin. Xeroderma Pigmentosum complementation group C (XPC) protein is involved in recognition of global genome DNA damages during NER (GG-NER) and it has been studied in different organisms due to its importance in other cellular processes. In this work, we studied NER proteins in Trypanosoma cruzi and Trypanosoma evansi, parasites of humans and animals respectively. Read More

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Diffuse Facial Hyperpigmentation as a Presenting Sign of Lupus Erythematosus: Three Cases and Review of the Literature.

Case Rep Dermatol 2021 May-Aug;13(2):263-270. Epub 2021 Jun 8.

Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Lupus erythematosus (LE) is an autoimmune disorder commonly affecting the skin; cutaneous lesions may indicate systemic involvement, warranting further evaluation. Photosensitivity, which may result in hyperpigmentation, is a well-known feature of the disease. In contrast, the prevalence of primary hyperpigmentation as a presenting sign of LE is not well established. Read More

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Prevalence of premalignant and malignant skin lesions in oculocutaneous albinism patients.

Rev Assoc Med Bras (1992) 2021 Jan;67(1):77-82

Hospital Universitário Professor Edgard Santos, Departamento de Dermatologia - Salvador (BA), Brasil.

Objective: Oculocutaneous albinism describes a group of pigmentary disorders that lead to skin sensitivity and predisposition to skin malignances.

Aims: To analyze clinical and epidemiological data in oculocutaneous albinism patients and to determine the prevalence of malignant skin lesions, assessing possible risk factors for skin cancer.

Methods: Cross-sectional study evaluating epidemiological data, habits of sun exposure and sun protection, and clinical examination of albino patients followed in a reference dermatology outpatient clinic in Brasil. Read More

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January 2021

Prochlorperazine-induced photoallergic reaction confirmed by photopatch test.

J Dermatol 2021 Sep 9;48(9):e464-e465. Epub 2021 Jun 9.

Department of Dermatology and Plastic Surgery, Akita University Graduate School of Medicine, Akita, Japan.

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September 2021

Japanese case of classic plaque-like actinic lichen planus.

J Dermatol 2021 Sep 9;48(9):e466-e467. Epub 2021 Jun 9.

Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Japan.

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September 2021

Oral manifestations of Hydroa vacciniforme-like lymphoproliferative disorder: a clinicopathological study of a Peruvian population.

J Oral Pathol Med 2021 Jul 29;50(6):530-539. Epub 2021 Jun 29.

Departamento de Patología, Medicina y Cirugía Oral, Facultad de Estomatología, Universidad Peruana Cayetano Heredia, Lima, Perú.

Background: Hydroa vacciniforme-like lymphoproliferative disorder (HVLPD) is a chronic Epstein-Barr virus (EBV)-positive lymphoproliferative disease which may either present as an indolent condition or progress to a systemic T-cell lymphoma.

Methods: All HVLPD diagnosed over a 10-year period were retrieved, and clinical data regarding sex, age, oral and systemic manifestations, and clinical follow-up were obtained. Immunohistochemistry was done in order to characterize the lymphoid cells, and in situ hybridization was used to demonstrate the presence of EBV. Read More

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Study of Minimal Erythema Dose in a Series of Solar Urticaria.

Actas Dermosifiliogr 2021 Jun 1;112(6):546-550. Epub 2021 Feb 1.

Departamento de Dermatología, Hospital Universitario de La Princesa, Madrid, Spain.

Background: Reduced minimal erythema dose (MED) is an abnormal erythematous reaction to light according to the skin phototype, which is determined by phototest. MED is reduced or abnormal in some photodermatoses. However, we have not found information about reduced MED in patients with solar urticarial (SU), a condition which causes hives after sun exposure. Read More

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UV Index Does Not Predict Ocular Ultraviolet Exposure.

Transl Vis Sci Technol 2021 06;10(7)

Department of Ophthalmology, School of Medicine, Kanazawa Medical University, Kahoku, Ishikawa, Japan.

Purpose: The ultraviolet index (UVI), available online, is an international linear scale of levels from 0 to 13+ that warns about the risk of sunburn; however, it does not address the risk to eyes. Our purpose was to develop a useful instrument to warn the public against ocular ultraviolet (OUV) exposure and to serve as a tool for researching UV-induced ocular diseases.

Methods: A rotating model head that included ultraviolet B (UVB) sensors documented UV irradiance at the crown and at the eyes spanning eight azimuths from sunrise to sunset under different climatic conditions in each season. Read More

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Linear Hyperpigmentation.

Am Fam Physician 2021 06;103(11):691-692

Patient First Urgent Care, Baltimore, MD, USA.

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Ichthyosis: case report in a Colombian man with genetic alterations in ABCA12 and HRNR genes.

BMC Med Genomics 2021 May 26;14(1):140. Epub 2021 May 26.

Grupo Neurociencia Y Cognición, Facultad de Psicología, Universidad Cooperativa de Colombia, Medellín, Colombia.

Background: Ichthyosis is a heterogeneous group of diseases caused by genetic disorders related to skin formation. They are characterized by generalized dry skin, scaling, hyperkeratosis and frequently associated with erythroderma. Among its different types, harlequin ichthyosis (HI) stands out due to its severity. Read More

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Assessing migraine patients with multifocal pupillographic objective perimetry.

BMC Neurol 2021 May 26;21(1):211. Epub 2021 May 26.

Eccles Institute of Neuroscience, the John Curtin School of Medical Research, Australian National University, Acton, ACT, Australia.

Background: To establish the effects of stimulating intrinsically-photosensitive retinal ganglion cells (ipRGCs) on migraine severity, and to determine if migraine produces objectively-measured visual field defects.

Methods: A randomized, open labelled, crossover study tested migraineurs and normal controls using multifocal pupillographic objective perimetry (mfPOP) with 44 test-regions/eye. A slow blue protocol (BP) stimulated ipRGCs, and a fast yellow protocol (YP) stimulated luminance channels. Read More

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Sensory neuron-derived TAFA4 promotes macrophage tissue repair functions.

Nature 2021 06 19;594(7861):94-99. Epub 2021 May 19.

Aix Marseille Univ., CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.

Inflammation is a defence response to tissue damage that requires tight regulation in order to prevent impaired healing. Tissue-resident macrophages have a key role in tissue repair, but the precise molecular mechanisms that regulate the balance between inflammatory and pro-repair macrophage responses during healing remain poorly understood. Here we demonstrate a major role for sensory neurons in promoting the tissue-repair function of macrophages. Read More

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Health Risks Associated With Excessive Exposure to Solar Ultraviolet Radiation Among Outdoor Workers in South Africa: An Overview.

Front Public Health 2021 28;9:678680. Epub 2021 Apr 28.

Biomedical Sciences, University of Edinburgh Medical School, Edinburgh, United Kingdom.

Exposure of outdoor workers to high levels of solar ultraviolet radiation (UVR) poses significant, well-known health risks including skin cancer and eye diseases. In South Africa, little is known about how many workers are potentially overexposed to solar UVR and what the associated impacts on their health might be. In this overview, the geography and solar UVR environment in South Africa are considered, as well as the different outdoor occupational groups likely to be affected by excessive solar UVR exposure. Read More

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