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Associations Between Psychological Constructs and Cardiac Biomarkers After Acute Coronary Syndrome.

Psychosom Med 2017 Apr;79(3):318-326

From the Harvard Medical School (Celano, Beach, Suarez, Motiwala, Gandhi, Gaggin, Januzzi, Healy, Huffman), Boston, Massachusetts; Department of Psychiatry (Celano, Beale, Beach, Suarez, Huffman), Massachusetts General Hospital, Boston, Massachusetts, Division of Cardiology, Department of Medicine (Belcher, Gandhi, Gaggin, Januzzi), Massachusetts General Hospital, Boston, Massachusetts; Division of Cardiology, Department of Medicine (Motiwala), Beth Israel Deaconess Medical Center, Boston, Massachusetts; and Biostatistics Center (Healy), Massachusetts General Hospital, Boston, Massachusetts.

Objective: Psychological constructs are associated with cardiovascular health, but the biological mechanisms mediating these relationships are unknown. We examined relationships between psychological constructs and markers of inflammation, endothelial function, and myocardial strain in a cohort of post-acute coronary syndrome (ACS) patients.

Methods: Participants (N = 164) attended study visits 2 weeks and 6 months after ACS. Read More

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