Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value.

Authors:
Atilgan Yilmaz
Atilgan Yilmaz
Department of Biosystems Science and Engineering
Mordecai Peretz
Mordecai Peretz
The Azrieli Center for Stem Cells and Genetic Research
Ido Sagi
Ido Sagi
Silberman Institute of Life Sciences
Israel
Nissim Benvenisty
Nissim Benvenisty
The Hebrew University
Israel

Cell Stem Cell 2016 11;19(5):569-572

The Azrieli Center for Stem Cells and Genetic Research, Department of Genetics, Silberman Institute of Life Sciences, The Hebrew University, Jerusalem 91904, Israel. Electronic address:

Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.

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Source
http://dx.doi.org/10.1016/j.stem.2016.10.009DOI Listing
November 2016
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