Lymphocytic Hypophysitis Mimicking Pituitary Macroadenoma

JAPI

April 2017 • Vol. 65

Lymphocytic hypophysitis is an inflammatory /autoimmune disorder that primarily involves the pituitary gland and the pituitary stalk. The common clinical presentations include headache, nausea, vomiting, fatigue, features of hypopituitarism and diabetes insipidus as well as diplopia, orbital pain and bitemporal hemianopia. We report a case of lymphocytic hypophysitis which presented as hemichorea. Neuroimaging showed a mass in the sella tursica region which, on histopathological examination was suggestive of lymphocytic hypophysitis. After excision of this mass, patient showed marked improvement in his symptoms albeit he developed panhypopituitarism. The patient was treated with pituitary hormonal replacement therapy and is currently asymptomatic.
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