Nanocomposite-Coated Silk-Based Artificial Conduits


In this study, silk filaments are coated with different concentrations (5, 7.5, and 10% w/w) of carbon nanofibers (CNFs) dispersed in poly-ε-caprolactone. The nanocomposite-coated silk filaments are subjected to knitting, braiding, and twisting. The tubular structures are covered with a silk fibroin/polyvinyl film for the nerve conduit application.


Results suggest that the CNF-based conducting nanocomposite coating in this well-defined architecture of the conduit helps in signal transmission and neural growth during the regeneration of the transected nerve.

Author Comments

Dr. Mamatha M Pillai, PhD
Dr. Mamatha M Pillai, PhD
Indian Institute of Technology, Bombay
Post Doctoral Fellow
Tissue engineering and regenerative medicine
Mumbai, Maharashtra | India
Writing this article was a great pleasure as it has co-authors with whom I have had long standing collaborations. I hope you find this article thought-provoking.Dr. Mamatha M Pillai, PhD



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