The aim of this article is to describe our case of metastatic recurrent RCC with sarcomatoid dedifferentiation in a 59 year old male patient cured with nephrectomy and multiple metastasectomies followed by Cabozantinib, while he was judged to be on palliative care, three years ago.
The importance of this case is that the patient was judged to be on palliative care, three years ago, and now he is having a normal life. The use of cabozantinib after Sunitinib failure was successful, but we think that it is the metastasectomy who had a benefic effect on disease free survival of our patient without any recurrence under cabozantinib. No data exists on the effect of metastasectomy before cabozantinib, this is why we think that this case allows us to discuss one more time, the indication of metastasectomy in the management of metastatic RCC.
It's a pleasure to share this case that highlights the important role of surgery in the treatment of renal cancer, despite the imperative role of medical treatment.Dr Johnny Boustany, MD
Boustany J., Abdessater M., Hachem C. El, Khoury Z. El, Khoury W. El, Khoury R. El Recurrent metastatic clear cell renal carcinoma with sarcomatoid dedifferentiation treated with surgery and Cabozantinib. Oncotarget. 2020; 11: 1922-1928. Retrieved from https://www.oncotarget.com/article/27543/