Isolation and structural elucidation of chondrosterins F-H from the marine fungus Chondrostereum sp.

Mar Drugs 2013 Feb 22;11(2):551-8. Epub 2013 Feb 22.

School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China.

The marine fungus Chondrostereum sp. was collected from a soft coral of the species Sarcophyton tortuosum from the South China Sea. Three new compounds, chondrosterins F-H (1, 4 and 5), together with three known compounds, incarnal (2), arthrosporone (3), and (2E)-decene-4,6,8-triyn-1-ol (6), were isolated. Their structures were elucidated primarily based on NMR and MS data. Incarnal (2) exhibited potent cytotoxic activity against various cancer cell lines.

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http://dx.doi.org/10.3390/md11020551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640397PMC
February 2013
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References

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Natural acetylenes. XXII. Trans-Dehydromatricaria ester as a biosynthetic precursor of some fungal polyacetylenes
Hodge et al.
J. Chem. Soc. Perkin Trans. 1 1966

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