Treatment of acute disseminated encephalomyelitis with intravenous immunoglobulin.

Neurology 2000 Mar;54(6):1370-2

McGill University Health Centre, the Montreal Neurological Hospital, Qu├ębec, Canada.

Acute disseminated encephalomyelitis (ADEM) is a presumed immune-mediated, demyelinating disease of the CNS for which the standard treatment is high-dose steroids. We describe two patients with ADEM in whom treatment with IV methylprednisolone coincided with deterioration in their clinical status. They were subsequently treated with IV immunoglobulin and exhibited dramatic clinical improvement, with return to their previous level of functioning.

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http://dx.doi.org/10.1212/wnl.54.6.1370DOI Listing
March 2000

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