Ventroposterolateral pallidotomy can abolish all parkinsonian symptoms.

Stereotact Funct Neurosurg 1992 ;58(1-4):14-21

Department of Neurosurgery, Sophiahemmet Hospital, Stockholm, Sweden.

Stereotactic ventroposterolateral pallidotomy in 46 parkinsonian patients resulted in a complete or almost complete and long-lasting relief of rigidity and hypokinesia in 91% of the patients. Good tremor effect was obtained in 80% of them. The L-dopa-induced dyskinesias, gait and speech improved in most patients. Complications were observed in 7 cases after 51 pallidotomies, i.e. 14% (partial homonymous hemianopia in 6 and transient dysphasia and facial weakness in 1). We believe that the good effect of surgery is based on interruption of some striopallidal or subthalamopallidal pathways.

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http://dx.doi.org/10.1159/000098965DOI Listing
December 1992
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