Intercontinental spread of pyrimethamine-resistant malaria.

Science 2004 Aug;305(5687):1124

London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

Here we present molecular evidence demonstrating that malaria parasites bearing high-level pyrimethamine resistance originally arrived in Africa from southeast Asia. The resistance alleles carried by these migrants are now spreading across Africa at an alarming rate, signaling the end of affordable malaria treatment and presenting sub-Saharan Africa with a public health crisis.

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Source
http://www.sciencemag.org/cgi/doi/10.1126/science.1098876
Publisher Site
http://dx.doi.org/10.1126/science.1098876DOI Listing
August 2004

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