Idiopathic hypereosinophilic syndrome in children: report of a 7-year-old boy with FIP1L1-PDGFRA rearrangement.

J Pediatr Hematol Oncol 2005 Dec;27(12):663-5

Hematology Department, Hospital Sant Joan de Déu, Barcelona, Spain.

Idiopathic hypereosinophilic syndrome (HES) in children is a very rare disorder; certain clinical differences with adult HES have been described, with no pediatric case with the imatinib-responsive FIP1L1-PDGFRA fusion gene reported to date. The authors describe the clinical course of three children with HES in whom FIP1L1-PDGFRA fusion gene was studied and report the first child with this rearrangement.

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http://dx.doi.org/10.1097/01.mph.0000193467.06938.77DOI Listing
December 2005
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