Analytical connotations of point-of-care testing.

Analyst 2010 Sep 6;135(9):2220-32. Epub 2010 Aug 6.

Department of Analytical Chemistry, Marie Curie Building (Annex), Campus de Rabanales, University of Cordoba, E-14071 Cordoba, Spain.

The main objective of this Tutorial Review is to approach the modern principles and practices of Analytical Chemistry to Point-of-Care Testing (POCT) systems in order to contribute to improve both the development of new devices and the reliable application of the existing ones. In this article, after contextualization of the topic, POCT systems (POCTs) are fully defined using several approaches. The requirements of a POCT system to be a robust and reliable tool available to patients and medical workers are described as well as their desirable complementary characteristics. In addition, the technical components of POCTs materialized in the implementation of the steps of the analytical processes (sample introduction, sample processing, visual or instrumental detection, and data processing) are outlined. Besides, analytical properties assigned to POCTs and to their quantitative and qualitative results are highlighted. Special emphasis is given to Quality Assurance and Quality Control procedures, which are essential aspects to achieving reliable results. Finally, decision making based on the results obtained with POCTs is discussed as are their benefits and drawbacks.

Download full-text PDF

Source
http://dx.doi.org/10.1039/c0an00307gDOI Listing
September 2010
7 Reads

Publication Analysis

Top Keywords

point-of-care testing
8
poct systems
8
medical workers
4
emphasis quality
4
quality assurance
4
tool patients
4
workers described
4
patients medical
4
special emphasis
4
desirable complementary
4
analytical
4
well desirable
4
assurance quality
4
described well
4
reliable tool
4
outlined analytical
4
control procedures
4
fully defined
4
procedures essential
4
pocts fully
4

References

(Supplied by CrossRef)

Valcárcel et al.
TrAC, Trends Anal. Chem. 2004

Valcárcel et al.
TrAC, Trends Anal. Chem. 1997

Valcárcel et al.
Anal. Chim. Acta 1999

Valcárcel et al.
TrAC, Trends Anal. Chem. 2000

Valcárcel et al.
Crit. Rev. Anal. Chem. 2000

Baena et al.
TrAC, Trends Anal. Chem. 2003

Simonet et al.
TrAC, Trends Anal. Chem. 2006

Valcárcel et al.
TrAC, Trends Anal. Chem. 1999

Valcárcel et al.
TrAC, Trends Anal. Chem. 2005

Valcárcel et al.
Anal. Bioanal. Chem. 2005

Sapsford et al.
Anal. Bioanal. Chem. 2009

Similar Publications