Adult mammalian neurogenesis and the New Zealand white rabbit.

Vet J 2008 Mar 27;175(3):310-31. Epub 2007 Mar 27.

Department of Veterinary Morphophysiology, University of Turin, Via Leonardo da Vinci 44, Grugliasco (TO), Italy.

Although the central nervous system is unable to undergo spontaneous repair and is hostile to the integration of exogenously delivered cells, various examples of adult structural plasticity have been shown to occur. It is now widely accepted that endogenous proliferative activity leading to the production of new neurons exists, at least within two restricted brain sites: the hippocampal dentate gyrus and the forebrain subventricular zone. A substantial insight into spontaneous neurogenesis within these allocortical regions in rodents has been obtained, but less is known regarding its occurrence in other mammalian brain regions. In this review, differences in the structural and temporal characteristics of protracted neurogenesis in mammals will be considered. Attention will be focused on the rabbit cerebrum and cerebellum, where unexpected features of structural plasticity have been found to occur despite the relative closeness of the Orders Lagomorpha and Rodentia.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tvjl.2007.01.023DOI Listing
March 2008
1 Read

Publication Analysis

Top Keywords

plasticity occur
8
structural plasticity
8
brain sites
4
restricted brain
4
exists restricted
4
will focused
4
attention will
4
sites hippocampal
4
dentate gyrus
4
considered attention
4
neurons exists
4
hippocampal dentate
4
production neurons
4
cerebrum cerebellum
4
endogenous proliferative
4
accepted endogenous
4
structural temporal
4
activity leading
4
gyrus forebrain
4
leading production
4

Similar Publications