Sporadic amyotrophic lateral sclerosis with extensive neurological involvement.

Acta Neuropathol 1992 ;84(2):211-5

Department of Neurology, Tokyo Women's Medical College, Japan.

We report an autopsy case of respirator-assisted long-survival sporadic amyotrophic lateral sclerosis (ALS) with extensive involvement extending beyond the motor system. The involved areas included the globus pallidus, subthalamic nucleus, red nucleus, substantia nigra, Clarke's column, intermediolateral nucleus, Onuf's (Onufrowicz) nucleus, middle root zone of the posterior column, and the spinocerebellar tract. There was no impairment of ocular movements. Such sporadic ALS cases with extensive involvement extending beyond the motor system may constitute a distinct subgroup of this disease that differs from long-survival ALS (with or without respirator support) in which only the motor system is affected.

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http://dx.doi.org/10.1007/BF00311398DOI Listing
October 1992

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References

(Supplied by CrossRef)

K Akiyama et al.
Byori to Rinshou 1987

H Hayashi et al.
J Neurol Sci 1989

A Hirano et al.
Arch Neurol 1967

A Hirano et al.
J Neuropathol Exp Neurol 1984

H Matsuoka et al.
Neuropathology 1991

I Nakano et al.
Neurol Med Chir (Tokyo) 1981

S Takeda et al.
Neuropathology 1991

Y Toyokura et al.
Jpn J Med 1977

A Tsutsumi et al.
Neuropathology 1985

M Yoshida et al.
Neuropathology 1991

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