Ugeskr Laeger 1997 Jun;159(25):3965-7
Peace Corps, Madagaskar.
J Drugs Dermatol 2003 Dec;2(6):662-3
Section of Dermatology, Department of Medicine, University of Chicago Hospitals, Chicago, Illinois 60637-1470, USA.
An uncommon manifestation of phototoxicity, photo-onycholysis results in the separation of the distal nail from the nail bed. Photo-onycholysis may follow the use of various medications or may occasionally be idiopathic. We present a case of photo-onycholysis in a patient treated with doxycycline for acne vulgaris. Read More
Ugeskr Laeger 2011 Feb;173(9):661-2
Dermato-venerologisk Afdeling, Bispebjerg Hospital, Denmark.
We present two cases of phototoxic onycholysis secondary to doxycycline treatment as malaria prophylaxis. Onycholysis is a rare side-effect to treatment with doxycycline and other tetracyclines. Some physicians are unaware of this risk. Read More
Pediatrics 2000 Jul;106(1):E13
Division of Biochemical Diseases, Department of Pediatrics, British Columbia's Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Photoonycholysis in association with a generalized phototoxic reaction or as an isolated event is a well-recognized complication of the tetracycline group of antibiotics. We describe a 14-year-old white girl with cystic fibrosis who developed photoonycholysis of all 20 nails while receiving treatment with doxycycline. Pediatricians who prescribe tetracyclines should be aware of this potential complication. Read More
BMJ 2004 Jul;329(7460):265
Netherlands Pharmacovigilance Centre Lareb, Goudsbloemvallei 7, 5327 MH 's-Hertogenbosch, Netherlands.