Pflugers Arch 1972 ;332:Suppl 332:R104
Curr Biol 2021 Jul 22. Epub 2021 Jul 22.
Massachusetts Institute of Technology, The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address:
The hippocampus and neocortex are theorized to be crucial partners in the formation of long-term memories. Here, we assess hippocampal involvement in two related forms of experience-dependent plasticity in the primary visual cortex (V1) of mice. Like control animals, those with hippocampal lesions exhibit potentiation of visually evoked potentials after passive daily exposure to a phase-reversing oriented grating stimulus, which is accompanied by long-term habituation of a reflexive behavioral response. Read More
J Neural Eng 2021 Jul 27;18(4). Epub 2021 Jul 27.
Department of Pathology, Keck USC School of Medicine, Los Angeles, CA, United States of America.
Intracortical microelectrode arrays (MEA) can be used as part of a brain-machine interface system to provide sensory feedback control of an artificial limb to assist persons with tetraplegia. Variability in functionality of electrodes has been reported but few studies in humans have examined the impact of chronic brain tissue responses revealed postmortem on electrode performanceIn a tetraplegic man, recording MEAs were implanted into the anterior intraparietal area and Brodmann's area 5 (BA5) of the posterior parietal cortex and a recording and stimulation array was implanted in BA1 of the primary somatosensory cortex (S1). The participant expired from unrelated causes seven months after MEA implantation. Read More
Sci Rep 2021 Jul 26;11(1):15158. Epub 2021 Jul 26.
Institute for Advanced Biomedical Technologies - ITAB, University G. D'Annunzio, Chieti-Pescara, Chieti, Italy.
Inhibitory control is the ability to suppress inappropriate movements and unwanted actions, allowing to regulate impulses and responses. This ability can be measured via the Stop Signal Task, which provides a temporal index of response inhibition, namely the stop signal reaction time (SSRT). At the neural level, Transcranial Magnetic Stimulation (TMS) allows to investigate motor inhibition within the primary motor cortex (M1), such as the cortical silent period (CSP) which is an index of GABA-mediated intracortical inhibition within M1. Read More
Neurosci Biobehav Rev 2021 Jul 23. Epub 2021 Jul 23.
Integrative Model-Based Cognitive Neuroscience Research Unit, University of Amsterdam, Nieuwe Achtergracht 129B, Postbus 15926, 1001 NK, Amsterdam, the Netherlands.
Interacting with our environment requires the selection of appropriate responses and the inhibition of others. Such effortful inhibition is achieved by a number of interference resolution and global inhibition processes. This meta-analysis including 57 studies and 73 contrasts revisits the overlap and differences in brain areas supporting interference resolution and global inhibition in cortical and subcortical brain areas. Read More
Development 2021 Jul 12;148(14). Epub 2021 Jul 12.
School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, SA 5000, Australia.
Bone morphogenetic protein (BMP) signaling is required for early forebrain development and cortical formation. How the endogenous modulators of BMP signaling regulate the structural and functional maturation of the developing brain remains unclear. Here, we show that expression of the BMP antagonist Grem1 marks committed layer V and VI glutamatergic neurons in the embryonic mouse brain. Read More