Protoplasma 1967 ;64(1):75-88
Phys Med Biol 2021 Jul 22. Epub 2021 Jul 22.
Central Research Laboratory, Hamamatsu Photonics K.K., Hamamatsu, JAPAN.
A multilayer depth-of-interaction positron emission tomography (DOI-PET) detector with an independent readout structure has a potential advantage as a time-of-flight (TOF)-PET detector. To evaluate the potential TOF capabilities of a multilayer DOI-PET detector, which consists of thin layers of a cerium-doped lutetium-yttrium oxyorthosilicate (LYSO:Ce) scintillator coupled to a multi-pixel photon counter (MPPC) array, we examined the detector's CTR performance via Monte Carlo simulations. We used several types of scintillator structures: a monolithic plate, laser-processing array with 3. Read More
J Chem Inf Model 2021 Jul 22. Epub 2021 Jul 22.
iMolecule, Center for Computational and Data-Intensive Science and Engineering, Skolkovo Institute of Science and Technology, Moscow 121205, Russia.
Peptides and peptide-based molecules represent a promising therapeutic modality targeting intracellular protein-protein interactions, potentially combining the beneficial properties of biologics and small-molecule drugs. Protein-peptide complexes occupy a unique niche of interaction interfaces with respect to protein-protein and protein-small molecule complexes. Protein-peptide binding site identification resembles image object detection, a field that had been revolutionalized with computer vision techniques. Read More
J Phys Chem Lett 2021 Jul 22:7100-7105. Epub 2021 Jul 22.
State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130021, China.
The formation of polymer-patch nanoparticles (PNPs) involves a condensation process of grafted chains on a nanoparticle (NP) surface, which is conventionally achieved via a fine-tuning of the solvent quality. However, such a critical solvent condition differs dramatically between polymers, and the formation mechanism of different patchy structures remains under debate. In this study, we demonstrate by a combined simulation and experimental study that such a surface-patterning process can be easily achieved via a simple solvent evaporation process, which creates a natural nonsolvent condition and is, in principle, adaptable for all polymers. Read More
Int J Audiol 2021 Jul 22:1-9. Epub 2021 Jul 22.
Institute for Behavioural Sciences and Learning, Linköping University, Linköping, Sweden.
Objectives: To investigate associations between sensitivity to temporal fine structure (TFS) and performance in cognitive and speech-in-noise recognition tests.Design: A binaural test of TFS sensitivity (the TFS-LF) was used. Measures of cognition included the reading span, Raven's, and text-reception threshold tests. Read More
Mammalia 2020 13;84(3):227-238. Epub 2019 Nov 13.
Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Small mammal communities in the Neotropics are composed largely of sigmodontine rodents. However, many questions regarding these communities remain unanswered, especially those pertaining to fine-scale sympatry and habitat selection. To address this, we examined sigmodontine community structure and vegetation in the western margin of the Upper Paraná Atlantic Forest and the southwestern-most extent of the Cerrado (CE) (an extensive South American savanna ecoregion) of Paraguay. Read More