Cancer 1965 Oct;18(10):1377-84
Int J Biol Macromol 2021 Jul 20;187:1-8. Epub 2021 Jul 20.
College of Light Industry and Food Engineering, Guangxi University, 100 Daxue Road, Nanning 530004, Guangxi, China; Sugar Industry Collaborative Innovation Center, Guangxi University, 100 Daxue Road, Nanning 530004, Guangxi, China. Electronic address:
The combined catalysis of glucose isomerase (GI) and D-psicose 3-epimerase (DPEase) provided a convenient route for the direct synthesis of D-allulose from d-glucose, whose cost is lower than d-fructose. In the present research, the weak activity of DPEase was the key rate-limiting step and resulted in the accumulation of d-fructose in engineered Bacillus subtilis. Then, the 5'-untranslated region (5'-UTR) structure of the mRNA translational initiation region was optimized for the precise control of DPEase expression. Read More
PLoS One 2021 22;16(7):e0254820. Epub 2021 Jul 22.
School of Economics and Management, Beijing Forestry University, Beijing, China.
The global population is rapidly increasing, the arable land area is losing in a large scale, and the water supply capacity is limited. Meanwhile, China is in a critical period of the transformation of apple industrial structure, and the improvement of apple production efficiency is an important way to increase farmers' output and income, moderate-scale operation is the inevitable trend in agricultural modernization. However, few studies have explored the production efficiency of the apple industry from the perspective of planting scale. Read More
Front Plant Sci 2021 5;12:671134. Epub 2021 Jul 5.
Institute of Agricultural Economics and Information, Jiangxi Academy of Agricultural Sciences, Nanchang, China.
The accurate classification of crop pests and diseases is essential for their prevention and control. However, datasets of pest and disease images collected in the field usually exhibit long-tailed distributions with heavy category imbalance, posing great challenges for a deep recognition and classification model. This paper proposes a novel convolutional rebalancing network to classify rice pests and diseases from image datasets collected in the field. Read More
J Health Serv Res Policy 2021 Jul 21:13558196211021618. Epub 2021 Jul 21.
Professor, Centre for Health Economics, University of York, UK.
Objective: People in disadvantaged areas are more likely to have an avoidable emergency hospital admission. Socio-economic inequality in avoidable emergency hospital admissions is monitored in England. Our aim was to inform local health care purchasing and planning by identifying recent health care system changes (or other factors), as reported by local health system leaders, that might explain narrowing or widening trends. Read More
Immunol Med 2021 Jul 21:1-9. Epub 2021 Jul 21.
Department of Clinical Research, National Hospital Organization Hokkaido Medical Center, Sapporo, Japan.
Since the initial observation of increased immunoglobulin concentrations in the cerebrospinal fluid of multiple sclerosis (MS) patients in the 1940s, B cells have been considered to participate in the pathology of MS through the production of autoantibodies reactive against central nervous system antigens. However, it is now recognized that B cells contribute to MS relapses antibody-independent activities, including the presentation of antigens to T cells and the release of pro-inflammatory cytokines. In addition, the recent identification of B cell-rich follicle-like structures in the meninges of progressive MS patients suggests that the pathogenic roles of B cells also exist at the progressive phase of this disease. Read More