Morphol Igazsagugyi Orv Sz 1986 Jul;26(3):181-6
Virchows Arch A Pathol Anat Histol 1980 ;388(1):87-103
Specimens from four cases of sclerema neonatorum were studied by light and electron microscopy. The connective tissue bands of the cutis and subcutis were thickened and alternated with loosely distributed bands in broad, distended areas of basal substance. Extensive areas areas filled with cross-banded structures were observed in the dermis. Read More
Pediatr Dermatol 1987 Aug;4(2):112-22
Department of Pathology, Micheal Reese Hospital and Medical Center, Chicago, IL 60616.
Sclerema neonatorum and subcutaneous fat necrosis are rare disorders affecting the panniculus of the newborn. This review attempts to put into perspective their similarities and differences in light of historical, biochemical, pathologic, and etiologic considerations. Recent therapeutic modalities and the prognosis are discussed. Read More
Indian J Pathol Microbiol 1993 Jan;36(1):45-7
Department of Pathology, R.G. Kar Medical College, Calcutta.
Histopathological study of 10 cases sclerema neonatorum showed subcutaneous fibrosis with lobulation in all the cases. 8 (80 percent) cases showed non-specific chronic inflammation of dermis and thinning of epidermis with atrophy of rete pegs and hypercollgenisation of dermis was evident in 70 percent cases. Fat necrosis with crystallisation of fat content was not a conspicuous feature. Read More