Context: Due to its rare incidence, molecular features of PA in young adults are largely unknown. Recently developed targeted mutational analysis identified aldosterone-driver somatic mutations in aldosterone-producing lesions, including aldosterone-producing adenomas (APAs), aldosterone-producing nodules (APNs), and aldosterone-producing micronodules, formerly known as aldosterone-producing cell clusters.Objective: To investigate histologic and genetic characteristics of lateralized PA in young adults.