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Evolutionary bioenergetics of ciliates.

Authors:
Michael Lynch Paul E Schavemaker Timothy J Licknack Yue Hao Arianna Pezzano

J Eukaryot Microbiol 2022 Jul 1:e12934. Epub 2022 Jul 1.

Ira A. Fulton Schools of Engineering, School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona, USA.

Understanding why various organisms evolve alternative ways of living requires information on both the fitness advantages of phenotypic modifications and the costs of constructing and operating cellular features. Although the former has been the subject of a myriad of ecological studies, almost no attention has been given to how organisms allocate resources to alternative structures and functions. We address these matters by capitalizing on an array of observations on diverse ciliate species and from the emerging field of evolutionary bioenergetics. A relatively robust and general estimator for the total cost of a cell per cell cycle (in units of ATP equivalents) is provided, and this is then used to understand how the magnitudes of various investments scale with cell size. Among other things, we examine the costs associated with the large macronuclear genomes of ciliates, as well as ribosomes, various internal membranes, osmoregulation, cilia, and swimming activities. Although a number of uncertainties remain, the general approach taken may serve as blueprint for expanding this line of work to additional traits and phylogenetic lineages.

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http://dx.doi.org/10.1111/jeu.12934DOI Listing
July 2022

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