Int Immunopharmacol 2022 Jun 28:109003. Epub 2022 Jun 28.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India; Mutagenicity Laboratory, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Laboratory Animal Facility, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India. Electronic address:
J Exp Med 1979 Mar;149(3):786-90
Secondary Tc cells generated against Sindbis virus (SIN) are restricted to Dk. All other H-2K or D regions tested show low specific responsiveness. F1 hybrids between low and high responders show dominance of responsiveness but lack complementation. Read More
Am J Psychiatry 1976 Jan;133(1):32-6
The serious long-term complications of maintenance antipsychotic therapy led the authors to undertake a critical review of outpatient withdrawal studies. Key findings included the following: 1) for a least 40% of outpatient schizophrenics, drugs seem to be essential for survival in the community; 2) the majority of patients who relapse after drug withdrawal recompensate fairly rapidly upon reinstitution of antipsychotic drug therapy; 3) placebo survivors seem to function as well as drug survivors--thus the benefit of maintenance drug therapy appears to be prevention of relapse; and 4) some cases of early relapse after drug withdrawal may be due to dyskinesia rather than psychotic decompensation. The authors urge clinicians to evaluate each patient on maintenance antipsychotic therapy in terms of feasibility of drug withdrawal and offer practical guidelines for withdrawal and subsequent management. Read More