Eur Respir J 2022 Aug 4;60(2). Epub 2022 Aug 4.
INSERM U 1151, Institut Necker Enfants Malades, Paris, France
Sci Rep 2022 02 2;12(1):1740. Epub 2022 Feb 2.
Department of Nuclear Medicine, Santiago de Compostela University Hospital, Santiago de Compostela, Spain.
The lack of a standardized cut-off value in the quantitative method and an inter-observer disagreement in the evaluation of the semiquantitative score in mTc-DPD scintigraphy leaves several patients with cardiac amyloidosis (CA) undiagnosed (grade 1 and H/CL: 1-1.49). This study aims to increase diagnostic productivity of mTc-DPD scintigraphy in CA. Read More
J Cyst Fibros 2022 05 21;21(3):448-455. Epub 2021 Dec 21.
Cystic Fibrosis Department, Institute of Mother and Child, Warsaw, Poland.
Background: Newborn screening for Cystic Fibrosis (CF) is associated with situations where the diagnosis of CF or CFTR related disorders (CFTR-RD) cannot be clearly ruled out.Materials/patients And Methods: We report a case series of 23 children with unconclusive diagnosis after newborn screening for CF and a mean follow-up of 7.7 years (4-13). Read More
Pediatrics 2021 12;148(6)
Respiratory Medicine, Department of Pediatrics.
Background And Objectives: Cystic fibrosis (CF) screen-positive infants with an inconclusive diagnosis (CFSPID) are infants in whom sweat testing and genetic analysis does not resolve a CF diagnosis. Lack of knowledge about the health outcome of these children who require clinical follow-up challenges effective consultation. Early predictive biomarkers to delineate the CF risk would allow a more targeted approach to these children. Read More
Res Microbiol 2015 Feb-Mar;166(2):102-10. Epub 2015 Jan 3.
Laboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Accurate species identification of the Sporothrix schenckii complex is essential, since identification based only on phenotypic characteristics is often inconclusive due to phenotypic variability within the species. We used matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for species identification of 70 environmental and clinical isolates of the Sporothrix complex. A reference database was established for MALDI-TOF MS-based species identification according to minor adjustments in the manufacturer's guidelines. Read More