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Spectrochim Acta A Mol Biomol Spectrosc 2022 Nov 22;280:121550. Epub 2022 Jun 22.

CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics and Shenzhen Key Laboratory of Synthetic Genomics. Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic address:

Alkaline phosphatase (ALP) is an important biomarker associated with diabetes, liver dysfunction, bone diseases, and breast cancer. Here we developed a method based on synergetic fluorescence recovery for the sensitive detection of ALP. Cadmium-zinc-selenium (CdZnSe) quantum dots (QDs) were prepared by one-pot water bath method without any complicated and rigorous conditions. Read More

Anal Chem 2022 05 23;94(18):6665-6671. Epub 2022 Apr 23.

The Faculty of Synthetic Biology, Shenzhen Insitute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.

Intracellular pH is an important regulator of cell function, and its subtle changes may greatly affect cell activities and cause diseases. Reliable imaging of intracellular pH remains a huge challenge. Dual-emitting Mn-doped quantum dots (QDs) can be directly used as a ratiometric fluorescent probe without further modification, but they displayed low performance in terms of photoluminescence, stability, and intensity ratio regulation. Read More

Adv Sci (Weinh) 2022 05 3;9(15):e2104488. Epub 2022 Mar 3.

Department of Applied Biology and Chemical Technology, Research Institute for Smart Energy and Guangdong-Hong Kong-Macao Joint Laboratory for Photonic-Thermal-Electrical Energy Materials and Devices, The Hong Kong Polytechnic University (PolyU), Hung Hom, Hong Kong, P. R. China.

A new strategy is developed in which cadmium-doped zinc sulfide (CdZnS) is used as the outermost shell to synthesize red, green, and blue (RGB) quantum dots (QDs) with the core/shell structures of CdZnSe/ZnSe/ZnS/CdZnS, CdZnSe/ZnSe/ZnSeS/CdZnS, and CdZnSe/ZnSeS/ZnS/CdZnS, respectively. Firstly, the inner ZnS and ZnSe shells confine the excitons inside the cores of QDs and provide a better lattice matching with respect to the outermost shell, which ensures high photoluminescence quantum yields of QDs. Secondly, the CdZnS shell affords its QDs with shallow valence bands (VBs). Read More

Anal Chem 2007 Dec 16;79(24):9452-8. Epub 2007 Nov 16.

Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669.

Water-soluble and stable quantum dots (QDs), CdTe and CdZnSe, are applied for ultrasensitive Pb(2+) detection. These QDs are capped with glutathione (GSH) shells. GSH and its polymeric form, phytochelatin, are employed by nature to detoxify heavy metal ions. Read More